Kai Sen Tan Department of Otolaryngology, Yong Loo Lin School of Medicine National University of Singapore Biography Publications Institution JoVE Articles Kai Sen Tan has not added a biography. If you are Kai Sen Tan and would like to personalize this page please email our Author Liaison for assistance. Publications Role of Yes-associated Protein in Interleukin-13 Induced Nasal Remodeling of Chronic Rhinosinusitis with Nasal Polyps Allergy. 02, 2021 | Pubmed ID: 33301614 Vaping and Respiratory Viruses: The End for ENDS? American Journal of Respiratory Cell and Molecular Biology. 01, 2021 | Pubmed ID: 33217237 Type 2-low Asthma Phenotypes by Integration of Sputum Transcriptomics and Serum Proteomics Allergy. 01, 2021 | Pubmed ID: 32865817 Hypoxia-induced Factor-1α Induces NLRP3 Expression by M1 Macrophages in Noneosinophilic Chronic Rhinosinusitis with Nasal Polyps Allergy. 02, 2021 | Pubmed ID: 32854144 Host Antiviral Response Suppresses Ciliogenesis and Motile Ciliary Functions in the Nasal Epithelium Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33409274 Infection of Human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt Deletion Isolate Lacking ORF8 Reveals Similar Viral Kinetics and Host Transcriptional Profiles PLoS Pathogens. 12, 2020 | Pubmed ID: 33284849 Interleukin-13 Alters Tight Junction Proteins Expression Thereby Compromising Barrier Function and Dampens Rhinovirus Induced Immune Responses in Nasal Epithelium Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33102478 Enteroviral 3C Protease Activates the Human NLRP1 Inflammasome in Airway Epithelia Science (New York, N.Y.). 12, 2020 | Pubmed ID: 33093214 P63Krt5 Basal Cells Are Increased in the Squamous Metaplastic Epithelium of Patients with Radiation-induced Chronic Rhinosinusitis Radiation Oncology (London, England). Sep, 2020 | Pubmed ID: 32977822 Long-term Defects of Nasal Epithelium Barrier Functions in Patients with Nasopharyngeal Carcinoma Post Chemo-radiotherapy Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Jul, 2020 | Pubmed ID: 32353641 FGF2, an Immunomodulatory Factor in Asthma and Chronic Obstructive Pulmonary Disease (COPD) Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32300593 The Origin, Transmission and Clinical Therapies on Coronavirus Disease 2019 (COVID-19) Outbreak - an Update on the Status Military Medical Research. 03, 2020 | Pubmed ID: 32169119 Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32161756 Proteomics Profiling of Epithelium-derived Exosomes from Nasal Polyps Revealed Signaling Functions Affecting Cellular Proliferation Respiratory Medicine. 02, 2020 | Pubmed ID: 32056672 Microarray Assay Reveals Ciliary Abnormalities of the Allergic Nasal Mucosa American Journal of Rhinology & Allergy. Jan, 2020 | Pubmed ID: 31450948 An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps Frontiers in Genetics. 2019 | Pubmed ID: 31798623 RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications Cells. 08, 2019 | Pubmed ID: 31461941 Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics Cells. 08, 2019 | Pubmed ID: 31455003 Whole-transcriptome Sequencing Reveals Heightened Inflammation and Defective Host Defence Responses in Chronic Rhinosinusitis with Nasal Polyps The European Respiratory Journal. 11, 2019 | Pubmed ID: 31439685 Upregulation of Cell-surface Mucin MUC15 in Human Nasal Epithelial Cells Upon Influenza A Virus Infection BMC Infectious Diseases. Jul, 2019 | Pubmed ID: 31307416 Distribution and Determinants of Dermatophagoides Mites Sensitization OfAllergic Rhinitis and Allergic Asthma in China International Archives of Allergy and Immunology. 2019 | Pubmed ID: 31104060 Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures Frontiers in Microbiology. 2018 | Pubmed ID: 30487780 A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium Frontiers in Immunology. 2018 | Pubmed ID: 30467502 Aberrant Localization of FOXJ1 Correlates with the Disease Severity and Comorbidities in Patients with Nasal Polyps Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 2018 | Pubmed ID: 30459817 Decreased Hospital Charges and Postoperative Pain in Septoplasty by Application of Enhanced Recovery After Surgery Therapeutics and Clinical Risk Management. 2018 | Pubmed ID: 30323609 H3N2 Influenza Virus Infection Enhances Oncostatin M Expression in Human Nasal Epithelium Experimental Cell Research. 10, 2018 | Pubmed ID: 30142324 Motile Ciliary Disorders in Chronic Airway Inflammatory Diseases: Critical Target for Interventions Current Allergy and Asthma Reports. 07, 2018 | Pubmed ID: 30046922 Sinus Computed Tomography Predicts Clinical Response to Corticosteroids in Chronic Rhinosinusitis with Nasal Polyps Clinical and Translational Allergy. 2018 | Pubmed ID: 29988550 Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa International Archives of Allergy and Immunology. 2018 | Pubmed ID: 29635245 CD151, a Novel Host Factor of Nuclear Export Signaling in Influenza Virus Infection The Journal of Allergy and Clinical Immunology. 05, 2018 | Pubmed ID: 29274410 In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses The Journal of Infectious Diseases. 03, 2018 | Pubmed ID: 29228279 Absence or Mislocalization of DNAH5 is a Characteristic Marker for Motile Ciliary Abnormality in Nasal Polyps The Laryngoscope. 03, 2018 | Pubmed ID: 29148098 Impact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis Current Allergy and Asthma Reports. Apr, 2017 | Pubmed ID: 28389843 MicroRNA-146a Induction During Influenza H3N2 Virus Infection Targets and Regulates TRAF6 Levels in Human Nasal Epithelial Cells (hNECs) Experimental Cell Research. 03, 2017 | Pubmed ID: 28131813 Human Nasal Epithelial Cells Derived from Multiple Subjects Exhibit Differential Responses to H3N2 Influenza Virus Infection In vitro The Journal of Allergy and Clinical Immunology. 07, 2016 | Pubmed ID: 26806046 Micro-RNAs in Regenerating Lungs: an Integrative Systems Biology Analysis of Murine Influenza Pneumonia BMC Genomics. 2014 | Pubmed ID: 25015185 Investigating the Efficacy of Pamidronate, a Chemical Inhibitor of Farnesyl Pyrophosphate Synthase, in the Inhibition of Influenza Virus Infection In vitro and In vivo Molecular Medicine Reports. Jan, 2014 | Pubmed ID: 24154548 In Vivo and in Vitro Studies on the Antiviral Activities of Viperin Against Influenza H1N1 Virus Infection The Journal of General Virology. Jun, 2012 | Pubmed ID: 22377585 用于研究呼吸道病毒感染期间先天免疫细胞活化的非接触式共培养模型 Zhe Zhang Ryan Lew*1, Jing Liu*1, Hsiao Hui Ong1, Vivian Jiayi Tan2, Annika Luukkainen3, Yew Kwang Ong1,4, Mark Thong1,4, Kia Joo Puan5, Vincent Tak Kwong Chow2,6, Kai Sen Tan1,2,6, De Yun Wang1,6 1Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 2Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 3Haartman Institute, Medicum, University of Helsinki, 4Department of Otolaryngology, Head and Neck Surgery, National University Hospital, National University Health System, 5Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network (SIgN), 6NUHS Infectious Diseases Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore JoVE 62115 면역학 및 감염병학
用于研究呼吸道病毒感染期间先天免疫细胞活化的非接触式共培养模型 Zhe Zhang Ryan Lew*1, Jing Liu*1, Hsiao Hui Ong1, Vivian Jiayi Tan2, Annika Luukkainen3, Yew Kwang Ong1,4, Mark Thong1,4, Kia Joo Puan5, Vincent Tak Kwong Chow2,6, Kai Sen Tan1,2,6, De Yun Wang1,6 1Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 2Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 3Haartman Institute, Medicum, University of Helsinki, 4Department of Otolaryngology, Head and Neck Surgery, National University Hospital, National University Health System, 5Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network (SIgN), 6NUHS Infectious Diseases Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore JoVE 62115 면역학 및 감염병학