Katrin Marcus Medizinisches Proteom-Center, Medical Faculty Ruhr-University Bochum Biography Publications Institution JoVE Articles Katrin Marcus has not added a biography. If you are Katrin Marcus and would like to personalize this page please email our Author Liaison for assistance. Publications Nematode CDC-37 and DNJ-13 Form Complexes and Can Interact with HSP-90 Scientific Reports. Nov, 2021 | Pubmed ID: 34725424 CSF Diagnostics: A Potentially Valuable Tool in Neurodegenerative and Inflammatory Disorders Involving Motor Neurons: A Review Diagnostics (Basel, Switzerland). Aug, 2021 | Pubmed ID: 34573864 N471D WASH Complex Subunit Strumpellin Knock-in Mice Display Mild Motor and Cardiac Abnormalities and BPTF and KLHL11 Dysregulation in Brain Tissue Neuropathology and Applied Neurobiology. Jul, 2021 | Pubmed ID: 34312900 The β-Subunit of Voltage-Gated Calcium Channels Regulates Cardiomyocyte Hypertrophy Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34307509 FLNC-Associated Myofibrillar Myopathy: New Clinical, Functional, and Proteomic Data Neurology. Genetics. Jun, 2021 | Pubmed ID: 34235269 Rat Retinae Data for Use As Spectral Library, for Pathway Remodeling As Well As Protein Mapping Data in Brief. Aug, 2021 | Pubmed ID: 34222568 Advanced Fiber Type-Specific Protein Profiles Derived from Adult Murine Skeletal Muscle Proteomes. Jun, 2021 | Pubmed ID: 34201234 HSP-90/kinase Complexes Are Stabilized by the Large PPIase FKB-6 Scientific Reports. 06, 2021 | Pubmed ID: 34117308 Establishing a Custom-Fit Data-Independent Acquisition Method for Label-Free Proteomics Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950500 Quantitative Mass Spectrometry-Based Proteomics: An Overview Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950486 Differential Proteome Analysis Using 2D-DIGE Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950485 Proteome Analysis with Classical 2D-PAGE Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950483 Protein Quantification Using the "Rapid Western Blot" Approach Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950481 Good Old-Fashioned Protein Concentration Determination by Amino Acid Analysis Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33950480 MicroRNAs from Extracellular Vesicles As a Signature for Parkinson's Disease Clinical and Translational Medicine. 04, 2021 | Pubmed ID: 33931970 Lysine 53 Acetylation of Cytochrome in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis Cells. 04, 2021 | Pubmed ID: 33916826 MaCPepDB: A Database to Quickly Access All Tryptic Peptides of the UniProtKB Journal of Proteome Research. 04, 2021 | Pubmed ID: 33724838 New Approaches to Critical Illness Polyneuromyopathy: High-Resolution Neuromuscular Ultrasound Characteristics and Cytokine Profiling Neurocritical Care. 08, 2021 | Pubmed ID: 33236290 The Process of Somatic Hypermutation Increases Polyreactivity for Central Nervous System Antigens in Primary Central Nervous System Lymphoma Haematologica. 03, 2021 | Pubmed ID: 32193251 Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson's Disease Cells. 12, 2020 | Pubmed ID: 33276480 The First Versatile Human IPSC-based Model of Ectopic Virus Induction Allows New Insights in RNA-virus Disease Scientific Reports. 10, 2020 | Pubmed ID: 33033381 A Patient-based Model of RNA Mis-splicing Uncovers Treatment Targets in Parkinson's Disease Science Translational Medicine. 09, 2020 | Pubmed ID: 32908004 How Do the Different Proteomic Strategies Cope with the Complexity of Biological Regulations in a Multi-Omic World? Critical Appraisal and Suggestions for Improvements Proteomes. Sep, 2020 | Pubmed ID: 32899323 Homozygous Expression of the Myofibrillar Myopathy-associated P.W2710X Filamin C Variant Reveals Major Pathomechanisms of Sarcomeric Lesion Formation Acta Neuropathologica Communications. 09, 2020 | Pubmed ID: 32887649 What Room for Two-Dimensional Gel-Based Proteomics in a Shotgun Proteomics World? Proteomes. Aug, 2020 | Pubmed ID: 32781532 Human Cerebrospinal Fluid Data for Use As Spectral Library, for Biomarker Research Data in Brief. Oct, 2020 | Pubmed ID: 32775566 Glucocorticoid Receptor Complexes Form Cooperatively with the Hsp90 Co-chaperones Pp5 and FKBPs Scientific Reports. 07, 2020 | Pubmed ID: 32612187 MiR-129-5p and MiR-130a-3p Regulate VEGFR-2 Expression in Sensory and Motor Neurons During Development International Journal of Molecular Sciences. May, 2020 | Pubmed ID: 32481647 Multiomic Elucidation of a Coding 99-mer Repeat-expansion Skeletal Muscle Disease Acta Neuropathologica. 08, 2020 | Pubmed ID: 32451610 CalibraCurve: A Tool for Calibration of Targeted MS-Based Measurements Proteomics. 06, 2020 | Pubmed ID: 32086983 Blood Contamination in CSF and Its Impact on Quantitative Analysis of Alpha-Synuclein Cells. 02, 2020 | Pubmed ID: 32033488 The Product PACRG Promotes TNF Signaling by Stabilizing LUBAC Science Signaling. 02, 2020 | Pubmed ID: 32019898 Reproducibility, Specificity and Accuracy of Relative Quantification Using Spectral Library-based Data-independent Acquisition Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699904 Chaperones in Sporadic Inclusion Body Myositis-Validation of Proteomic Data Muscle & Nerve. 01, 2020 | Pubmed ID: 31644823 Let Me Infuse This for You - A Way to Solve the First YPIC Challenge EuPA Open Proteomics. Mar, 2019 | Pubmed ID: 31890549 A Metastable Subproteome Underlies Inclusion Formation in Muscle Proteinopathies Acta Neuropathologica Communications. 12, 2019 | Pubmed ID: 31796104 A Spiked Human Proteomic Dataset from Human Osteogenic Differentiated BMSCs and ASCs for Use As a Spectral Library, for Modelling Pathways As Well As Protein Mapping Data in Brief. Dec, 2019 | Pubmed ID: 31763404 CRN2 Binds to TIMP4 and MMP14 and Promotes Perivascular Invasion of Glioblastoma Cells European Journal of Cell Biology. Dec, 2019 | Pubmed ID: 31677819 Co-extraction for Metabolomics and Proteomics from a Single CSF Sample Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31432423 CSF Sample Preparation for Data-Independent Acquisition Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31432406 Human Tear Fluid Proteome Dataset for Usage As a Spectral Library and for Protein Modeling Data in Brief. Apr, 2019 | Pubmed ID: 31372408 IgA Autoantibodies Against Native Myelin Basic Protein in a Patient with MS Neurology(R) Neuroimmunology & Neuroinflammation. 07, 2019 | Pubmed ID: 31355305 Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men Nutrients. May, 2019 | Pubmed ID: 31091754 The MicroRNA MiR-375-3p and the Tumor Suppressor NDRG2 Are Involved in Sporadic Amyotrophic Lateral Sclerosis Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2019 | Pubmed ID: 31075191 Noninvasive Diagnosis of Urothelial Cancer in Urine Using DNA Hypermethylation Signatures-Gender Matters International Journal of Cancer. 11, 2019 | Pubmed ID: 31008534 Integrated Fourier Transform Infrared Imaging and Proteomics for Identification of a Candidate Histochemical Biomarker in Bladder Cancer The American Journal of Pathology. 03, 2019 | Pubmed ID: 30770125 Quantifying Changes in the Bacterial Thiol Redox Proteome During Host-pathogen Interaction Redox Biology. 02, 2019 | Pubmed ID: 30682706 Protein Inference Using PIA Workflows and PSI Standard File Formats Journal of Proteome Research. 02, 2019 | Pubmed ID: 30474983 Landscape of Pain in Parkinson's Disease: Impact of Gender Differences Neurological Research. Jan, 2019 | Pubmed ID: 30311863 Intricate Crosstalk Between Lipopolysaccharide, Phospholipid and Fatty Acid Metabolism in Modulates Proteolysis of LpxC Frontiers in Microbiology. 2018 | Pubmed ID: 30692974 Protein Variability in Cerebrospinal Fluid and Its Possible Implications for Neurological Protein Biomarker Research PloS One. 2018 | Pubmed ID: 30496192 Characterization of Cerebrospinal Fluid Via Data-Independent Acquisition Mass Spectrometry Journal of Proteome Research. 10, 2018 | Pubmed ID: 30207155 Label-free Identification of Myopathological Features with Coherent Anti-Stokes Raman Scattering Muscle & Nerve. 09, 2018 | Pubmed ID: 29663456 Editorial: Breakthroughs in Top-down Proteomics Journal of Proteomics. 03, 2018 | Pubmed ID: 29275042 Autophagy Inhibition Promotes SNCA/alpha-synuclein Release and Transfer Via Extracellular Vesicles with a Hybrid Autophagosome-exosome-like Phenotype Autophagy. 2018 | Pubmed ID: 29198173 Molecularly Imprinted Polymers Synthesized Via Template Immobilization on Fumed Silica Nanoparticles for the Enrichment of Phosphopeptides Journal of Molecular Recognition : JMR. 03, 2018 | Pubmed ID: 29024117 Hsp90-downregulation Influences the Heat-shock Response, Innate Immune Response and Onset of Oocyte Development in Nematodes PloS One. 2017 | Pubmed ID: 29078207 One Gene, Two Proteins: Coordinated Production of a Copper Chaperone by Differential Transcript Formation And translational Frameshifting in Escherichia Coli Molecular Microbiology. Nov, 2017 | Pubmed ID: 28925527 Distinct Metabolomic Signature in Cerebrospinal Fluid in Early Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2017 | Pubmed ID: 28843022 Protective Effects on the Retina After Ranibizumab Treatment in an Ischemia Model PloS One. 2017 | Pubmed ID: 28800629 BioInfra.Prot: A Comprehensive Proteomics Workflow Including Data Standardization, Protein Inference, Expression Analysis and Data Publication Journal of Biotechnology. Nov, 2017 | Pubmed ID: 28606611 Spatial and Molecular Resolution of Diffuse Malignant Mesothelioma Heterogeneity by Integrating Label-free FTIR Imaging, Laser Capture Microdissection and Proteomics Scientific Reports. 03, 2017 | Pubmed ID: 28358042 Strategies in Relative and Absolute Quantitative Mass Spectrometry Based Proteomics Biological Chemistry. 05, 2017 | Pubmed ID: 28282288 Metabolic Profiling of Body Fluids and Multivariate Data Analysis MethodsX. 2017 | Pubmed ID: 28275554 Morphological Plasticity of Emerging Purkinje Cells in Response to Exogenous VEGF Frontiers in Molecular Neuroscience. 2017 | Pubmed ID: 28194096 Proteomics of Rimmed Vacuoles Define New Risk Allele in Inclusion Body Myositis Annals of Neurology. Feb, 2017 | Pubmed ID: 28009083 Proteomic Characterization of Neuromelanin Granules Isolated from Human Substantia Nigra by Laser-microdissection Scientific Reports. 11, 2016 | Pubmed ID: 27841354 Validation of Molecularly Imprinted Polymers for Side Chain Selective Phosphopeptide Enrichment Journal of Chromatography. A. Nov, 2016 | Pubmed ID: 27765418 Membrane Tethering of APP C-terminal Fragments is a Prerequisite for T668 Phosphorylation Preventing Nuclear Sphere Generation Cellular Signalling. 11, 2016 | Pubmed ID: 27534516 Mutant Desmin Substantially Perturbs Mitochondrial Morphology, Function and Maintenance in Skeletal Muscle Tissue Acta Neuropathologica. 09, 2016 | Pubmed ID: 27393313 Key Players in Neurodegenerative Disorders in Focus-New Insights into the Proteomic Profile of Alzheimer's Disease, Schizophrenia, ALS, and Multiple Sclerosis-24th HUPO BPP Workshop: September 29, 2015, Vancouver, Canada Proteomics. Apr, 2016 | Pubmed ID: 26872682 PAA: an R/bioconductor Package for Biomarker Discovery with Protein Microarrays Bioinformatics (Oxford, England). 05, 2016 | Pubmed ID: 26803161 Nuclear Spheres Modulate the Expression of BEST1 and GADD45G Cellular Signalling. Jan, 2016 | Pubmed ID: 26521045 Myofibrillar Instability Exacerbated by Acute Exercise in Filaminopathy Human Molecular Genetics. Dec, 2015 | Pubmed ID: 26472074 Amyloid-β As a Biomarker for Alzheimer's Disease: Quantification Methods in Body Fluids Expert Review of Proteomics. Aug, 2015 | Pubmed ID: 26153725 Low-bias Phosphopeptide Enrichment from Scarce Samples Using Plastic Antibodies Scientific Reports. Jul, 2015 | Pubmed ID: 26126808 Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015 | Pubmed ID: 26116512 Indirect Protein Quantification of Drug-transforming Enzymes Using Peptide Group-specific Immunoaffinity Enrichment and Mass Spectrometry Scientific Reports. Mar, 2015 | Pubmed ID: 25737130 The Challenge of On-tissue Digestion for MALDI MSI- a Comparison of Different Protocols to Improve Imaging Experiments Analytical and Bioanalytical Chemistry. Mar, 2015 | Pubmed ID: 25687681 Identification of a Novel Human LAP1 Isoform That is Regulated by Protein Phosphorylation PloS One. 2014 | Pubmed ID: 25461922 Chromophore Composition of the Phycobiliprotein Cr-PC577 from the Cryptophyte Hemiselmis Pacifica Photosynthesis Research. Dec, 2014 | Pubmed ID: 25134685 Frontiers in Neurodegeneration--new Insights and Prospects--20th HUPO BPP Workshop: 15 September 2013, Yokohama, Japan Proteomics. Jun, 2014 | Pubmed ID: 24903697 Internal Ribosomal Entry Site (IRES) Activity Generates Endogenous Carboxyl-terminal Domains of Cx43 and is Responsive to Hypoxic Conditions The Journal of Biological Chemistry. Jul, 2014 | Pubmed ID: 24872408 Overexpression of the Calpain-specific Inhibitor Calpastatin Reduces Human Alpha-Synuclein Processing, Aggregation and Synaptic Impairment in [A30P]αSyn Transgenic Mice Human Molecular Genetics. Aug, 2014 | Pubmed ID: 24619358 Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 2 (SERCA2) As New Binding Proteins in the Human Brain Molecular & Cellular Proteomics : MCP. Feb, 2014 | Pubmed ID: 24284412 Not So Pseudo: the Evolutionary History of Protein Phosphatase 1 Regulatory Subunit 2 and Related Pseudogenes BMC Evolutionary Biology. Nov, 2013 | Pubmed ID: 24195737 Early Diagnosis of Neurodegenerative Diseases - the Long Awaited Holy Grail and Bottleneck of Modern Brain Research - 19th HUPO BPP Workshop: May 22-24, 2013, Dortmund, Germany Proteomics. Oct, 2013 | Pubmed ID: 24108682 FE65 Regulates and Interacts with the Bloom Syndrome Protein in Dynamic Nuclear Spheres - Potential Relevance to Alzheimer's Disease Journal of Cell Science. Jun, 2013 | Pubmed ID: 23572515 Identification and Characterization of Two Distinct PPP1R2 Isoforms in Human Spermatozoa BMC Cell Biology. Mar, 2013 | Pubmed ID: 23506001 Changes in Interleukin-1 Alpha Serum Levels After Transplantation of Umbilical Cord Blood Cells in a Model of Perinatal Hypoxic-ischemic Brain Damage Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Mar, 2013 | Pubmed ID: 23123184 A Combined Laser Microdissection and Mass Spectrometry Approach Reveals New Disease Relevant Proteins Accumulating in Aggregates of Filaminopathy Patients Molecular & Cellular Proteomics : MCP. Jan, 2013 | Pubmed ID: 23115302 A Ternary Complex Consisting of AICD, FE65, and TIP60 Down-regulates Stathmin1 Biochimica Et Biophysica Acta. Jan, 2013 | Pubmed ID: 22902274 Proteomic Analysis of Alterations Induced by Perinatal Hypoxic-ischemic Brain Injury Journal of Proteome Research. Dec, 2012 | Pubmed ID: 23153068 Stepwise Isolation of Human Peripheral Erythrocytes, T Lymphocytes, and Monocytes for Blood Cell Proteomics Proteomics. Clinical Applications. Oct, 2012 | Pubmed ID: 22930584 The Amyloid Precursor Protein (APP) Family Members Are Key Players in S-adenosylmethionine Formation by MAT2A and Modify BACE1 and PSEN1 Gene Expression-relevance for Alzheimer's Disease Molecular & Cellular Proteomics : MCP. Nov, 2012 | Pubmed ID: 22879628 La Transplantation De Cellules De Sang De Cordon Ombilical Humain Médiée Par Des Effets Bénéfiques Sur L'apoptose, L'angiogenèse Et La Survie Des Neurones Après Une Lésion Cérébrale Hypoxique-ischémique Chez Les Rats Cell and Tissue Research. Jun, 2012 | Pubmed ID: 22526623 A53T-alpha-synuclein-overexpression in the Mouse Nigrostriatal Pathway Leads to Early Increase of 14-3-3 Epsilon and Late Increase of GFAP Journal of Neural Transmission (Vienna, Austria : 1996). Mar, 2012 | Pubmed ID: 21960009 Sense and Nonsense of Pathway Analysis Software in Proteomics Journal of Proteome Research. Dec, 2011 | Pubmed ID: 21978018 A Systems Biology Approach to Dynamic Modeling and Inter-subject Variability of Statin Pharmacokinetics in Human Hepatocytes BMC Systems Biology. 2011 | Pubmed ID: 21548957 Keratin 23, a Novel DPC4/Smad4 Target Gene Which Binds 14-3-3ε BMC Cancer. Apr, 2011 | Pubmed ID: 21492476 The Amyloid Precursor Protein Intracellular Domain (AICD) As Modulator of Gene Expression, Apoptosis, and Cytoskeletal Dynamics-relevance for Alzheimer's Disease Progress in Neurobiology. Aug, 2008 | Pubmed ID: 18603345 A New Fast Method for NanoLC-MALDI-TOF/TOF-MS Analysis Using Monolithic Columns for Peptide Preconcentration and Separation in Proteomic Studies Journal of Proteome Research. Feb, 2007 | Pubmed ID: 17269720 Multidimensional Chromatography: a Powerful Tool for the Analysis of Membrane Proteins in Mouse Brain Journal of Proteome Research. Jan, 2007 | Pubmed ID: 17203954 Pilot Study of the Human Proteome Organisation Brain Proteome Project: Applying Different 2-DE Techniques to Monitor Proteomic Changes During Murine Brain Development Proteomics. Sep, 2006 | Pubmed ID: 16927428 5th HUPO BPP Bioinformatics Meeting at the European Bioinformatics Institute in Hinxton, UK--Setting the Analysis Frame Proteomics. Sep, 2005 | Pubmed ID: 16167371 HUPO BPP Workshop on Mouse Models for Neurodegeneration--Choosing the Right Models Proteomics. Sep, 2005 | Pubmed ID: 16127735 Application of Fluorescence Difference Gel Electrophoresis Saturation Labelling for the Analysis of Microdissected Precursor Lesions of Pancreatic Ductal Adenocarcinoma Proteomics. Jul, 2005 | Pubmed ID: 15924292 Tryptic Transpeptidation Products Observed in Proteome Analysis by Liquid Chromatography-tandem Mass Spectrometry Proteomics. Mar, 2005 | Pubmed ID: 15759313 Two-dimensional Polyacrylamide Gel Electrophoresis for Platelet Proteomics Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15308816 "Does Understanding the Brain Need Proteomics and Does Understanding Proteomics Need Brains?"--Second HUPO HBPP Workshop Hosted in Paris Proteomics. Jul, 2004 | Pubmed ID: 15221752 Differential Analysis of Phosphorylated Proteins in Resting and Thrombin-stimulated Human Platelets Analytical and Bioanalytical Chemistry. Aug, 2003 | Pubmed ID: 12904942 Protocole basé sur la microdissection laser pour l’analyse LC-MS/MS du profil protéomique des granules de neuromélanine Maximilian Wulf1,2, Katalin Barkovits-Boeddinghaus1,2, Paula Sommer1,2, Karin Schork1,2, Martin Eisenacher1,2, Peter Riederer3,4, Manfred Gerlach5, Steffen Kösters1,2, Britta Eggers*1,2, Katrin Marcus*1,2 1Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, 2Medical Proteome Analysis, Center for Proteindiagnostics (PRODI), Ruhr-University Bochum, 3Center of Mental Health; Clinic and Policlinic for Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, 4Psychiatry Department of Clinical Research, University of Southern Denmark Odense University Hospital, 5Center of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, University of Wuerzburg JoVE 63289 신경과학
Protocole basé sur la microdissection laser pour l’analyse LC-MS/MS du profil protéomique des granules de neuromélanine Maximilian Wulf1,2, Katalin Barkovits-Boeddinghaus1,2, Paula Sommer1,2, Karin Schork1,2, Martin Eisenacher1,2, Peter Riederer3,4, Manfred Gerlach5, Steffen Kösters1,2, Britta Eggers*1,2, Katrin Marcus*1,2 1Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, 2Medical Proteome Analysis, Center for Proteindiagnostics (PRODI), Ruhr-University Bochum, 3Center of Mental Health; Clinic and Policlinic for Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, 4Psychiatry Department of Clinical Research, University of Southern Denmark Odense University Hospital, 5Center of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, University of Wuerzburg JoVE 63289 신경과학