Lei Wu Core Facility of West China Hospital Sichuan University Biography Publications Institution JoVE Articles Lei Wu has not added a biography. If you are Lei Wu and would like to personalize this page please email our Author Liaison for assistance. Publications Evolving Landscape of Treatments Targeting the Microenvironment of Liver Metastases in Non-small Cell Lung Cancer Chinese Medical Journal. Jan, 2024 | Pubmed ID: 38251678 Antibacterial and DNA-Based Hydrogels In Situ Block TNF-α to Promote Diabetic Alveolar Bone Rebuilding Macromolecular Rapid Communications. Nov, 2023 | Pubmed ID: 38014713 Multifunctional DNA-Based Hydrogel Promotes Diabetic Alveolar Bone Defect Reconstruction Small (Weinheim an Der Bergstrasse, Germany). Nov, 2023 | Pubmed ID: 37919857 Low-Temperature Assembling Strategy of a Nacre-Inspired Lamellar Configuration to Upcycling Biaxially Oriented Polypropylene Film Waste ACS Omega. Aug, 2023 | Pubmed ID: 37663481 A Robust Mixed-charge Zwitterionic Polyurethane Coating Integrated with Antibacterial and Anticoagulant Functions for Interventional Blood-contacting Devices Journal of Materials Chemistry. B. Aug, 2023 | Pubmed ID: 37530181 Identification of Priority Pathogens for Aetiological Diagnosis in Adults with Community-acquired Pneumonia in China: a Multicentre Prospective Study BMC Infectious Diseases. Apr, 2023 | Pubmed ID: 37059987 Sustained Delivery of IL-10 by Self-assembling Peptide Hydrogel to Reprogram Macrophages and Promote Diabetic Alveolar Bone Defect Healing Dental Materials : Official Publication of the Academy of Dental Materials. Apr, 2023 | Pubmed ID: 36931990 Efficacy and Safety of Neoadjuvant Immunotherapy in Resectable Esophageal or Gastroesophageal Junction Carcinoma: A Pooled Analysis of Prospective Clinical Trials Frontiers in Immunology. 2022 | Pubmed ID: 36591306 Mimicking Natural Cholesterol Assimilation to Elevate the Oral Delivery of Liraglutide for Type II Diabetes Therapy Asian Journal of Pharmaceutical Sciences. Aug, 2022 | Pubmed ID: 36382301 CT-based Transformer Model for Non-invasively Predicting the Fuhrman Nuclear Grade of Clear Cell Renal Cell Carcinoma Frontiers in Oncology. 2022 | Pubmed ID: 36249050 Treatment Outcomes of Injectable Thermosensitive Hydrogel Containing Bevacizumab in Intervertebral Disc Degeneration Frontiers in Bioengineering and Biotechnology. 2022 | Pubmed ID: 36213074 Milk-derived Exosomes Exhibit Versatile Effects for Improved Oral Drug Delivery Acta Pharmaceutica Sinica. B. Apr, 2022 | Pubmed ID: 35847507 Physically Cross-Linked DNA Hydrogel-Based Sustained Cytokine Delivery for Diabetic Alveolar Bone Rebuilding ACS Applied Materials & Interfaces. Jun, 2022 | Pubmed ID: 35638566 A Multi-Scale Simulation Study of Irradiation Swelling of Silicon Carbide Materials (Basel, Switzerland). Apr, 2022 | Pubmed ID: 35591343 Pulsed Electromagnetic Fields Attenuate Glucocorticoid-induced Bone Loss by Targeting Senescent LepR Bone Marrow Mesenchymal Stromal Cells Biomaterials Advances. Feb, 2022 | Pubmed ID: 35527160 An Extension of the RIGHT Statement for Introductions and Interpretations of Clinical Practice Guidelines: RIGHT for INT Journal of Evidence-based Medicine. Mar, 2022 | Pubmed ID: 35416438 A DNA Nanoraft-Based Cytokine Delivery Platform for Alleviation of Acute Kidney Injury ACS Nano. Nov, 2021 | Pubmed ID: 34723467 Identification of MDM2, YTHDF2 and DDX21 As Potential Biomarkers and Targets for Treatment of Type 2 Diabetes Biochemical and Biophysical Research Communications. Dec, 2021 | Pubmed ID: 34688145 Self-Stabilized Supramolecular Assemblies Constructed from PEGylated Dendritic Peptide Conjugate for Augmenting Tumor Retention and Therapy Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Nov, 2021 | Pubmed ID: 34623034 Halogen-Free Flame Retardant Polypropylene Fibers with Modified Intumescent Flame Retardant: Preparation, Characterization, Properties and Mode of Action Polymers. Jul, 2021 | Pubmed ID: 34372156 Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Frontiers in Neurology. 2021 | Pubmed ID: 33897605 A Chromosome-scale Reference Genome of Lobularia Maritima, an Ornamental Plant with High Stress Tolerance Horticulture Research. Dec, 2020 | Pubmed ID: 33328471 A Novel in Silico Antimicrobial Peptide DP7 Combats MDR Pseudomonas Aeruginosa and Related Biofilm Infections The Journal of Antimicrobial Chemotherapy. Nov, 2020 | Pubmed ID: 32737484 Promoting Apical-to-basolateral Unidirectional Transport of Nanoformulations by Manipulating the Nutrient-absorption Pathway Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2020 | Pubmed ID: 32277961 Nanoparticles with Surface Features of Dendritic Oligopeptides As Potential Oral Drug Delivery Systems Journal of Materials Chemistry. B. Apr, 2020 | Pubmed ID: 32129375 Structure and Properties of Halogen-free Flame Retardant and Phosphorus-containing Aromatic Poly(1,3,4-oxadiazole)s Fiber RSC Advances. Mar, 2019 | Pubmed ID: 35519946 Prevotella Copri is Associated with Carboplatin-induced Gut Toxicity Cell Death & Disease. Sep, 2019 | Pubmed ID: 31558709 Iron-mimic Peptide Converts Transferrin from Foe to Friend for Orally Targeting Insulin Delivery Journal of Materials Chemistry. B. Jan, 2018 | Pubmed ID: 32254488 Multifunctional Nanoparticles Enable Efficient Oral Delivery of Biomacromolecules Via Improving Payload Stability and Regulating the Transcytosis Pathway ACS Applied Materials & Interfaces. Oct, 2018 | Pubmed ID: 30207680 Novel Self-Assembled Micelles Based on Cholesterol-Modified Antimicrobial Peptide (DP7) for Safe and Effective Systemic Administration in Animal Models of Bacterial Infection Antimicrobial Agents and Chemotherapy. Nov, 2018 | Pubmed ID: 30201818 Transport Mechanisms of Butyrate Modified Nanoparticles: Insight into "Easy Entry, Hard Transcytosis" of Active Targeting System in Oral Administration Molecular Pharmaceutics. Sep, 2018 | Pubmed ID: 30102863 Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity Are Related to Immune Response and Gut Microbiota EBioMedicine. Jul, 2018 | Pubmed ID: 30049384 Novel Solid Lipid Nanoparticle with Endosomal Escape Function for Oral Delivery of Insulin ACS Applied Materials & Interfaces. Mar, 2018 | Pubmed ID: 29484890 The Combination of Endolysosomal Escape and Basolateral Stimulation to Overcome the Difficulties of "easy Uptake Hard Transcytosis" of Ligand-modified Nanoparticles in Oral Drug Delivery Nanoscale. Jan, 2018 | Pubmed ID: 29303184 Engineering Nanomaterials to Overcome the Mucosal Barrier by Modulating Surface Properties Advanced Drug Delivery Reviews. Jan, 2018 | Pubmed ID: 28989056 Enhanced Nuclear Delivery of Anti-cancer Drugs Using Micelles Containing Releasable Membrane Fusion Peptide and Nuclear-targeting Retinoic Acid Journal of Materials Chemistry. B. Sep, 2017 | Pubmed ID: 32263908 A Strategy for Developing Effective Orally-delivered Nanoparticles Through Modulation of the Surface "hydrophilicity/hydrophobicity Balance" Journal of Materials Chemistry. B. Feb, 2017 | Pubmed ID: 32263598 Bioinspired Butyrate-functionalized Nanovehicles for Targeted Oral Delivery of Biomacromolecular Drugs Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2017 | Pubmed ID: 28774842 Systematic Evaluation of the Toxicity and Biodistribution of Virus Mimicking Mucus-penetrating DLPC-NPs As Oral Drug Delivery System International Journal of Pharmaceutics. Sep, 2017 | Pubmed ID: 28743553 Lipid Nanovehicles with Adjustable Surface Properties for Overcoming Multiple Barriers Simultaneously in Oral Administration International Journal of Pharmaceutics. Mar, 2017 | Pubmed ID: 28185960 Subcellular Co-delivery of Two Different Site-oriented Payloads for Tumor Therapy Nanoscale. Jan, 2017 | Pubmed ID: 28067924 A PH-responsive Sequential-disassembly Nanohybrid for Mitochondrial Targeting Nanoscale. Jan, 2017 | Pubmed ID: 27910990 Core-shell Stability of Nanoparticles Plays an Important Role for Overcoming the Intestinal Mucus and Epithelium Barrier Journal of Materials Chemistry. B. Sep, 2016 | Pubmed ID: 32263756 Highly Efficient Extraction of Actinides with Pillar[5]arene-derived Diglycolamides in Ionic Liquids Via a Unique Mechanism Involving Competitive Host-guest Interactions Dalton Transactions (Cambridge, England : 2003). Dec, 2016 | Pubmed ID: 27872927 Enhanced Oral Delivery of Protein Drugs Using Zwitterion-Functionalized Nanoparticles to Overcome Both the Diffusion and Absorption Barriers ACS Applied Materials & Interfaces. Sep, 2016 | Pubmed ID: 27588330 Role of Reactive Oxygen Species-mediated MAPK and NF-κB Activation in Polygonatum Cyrtonema Lectin-induced Apoptosis and Autophagy in Human Lung Adenocarcinoma A549 Cells Journal of Biochemistry. Dec, 2016 | Pubmed ID: 27318358 Rheological Properties of Glutaraldehyde-crosslinked Collagen Solutions Analyzed Quantitatively Using Mechanical Models Materials Science & Engineering. C, Materials for Biological Applications. Jun, 2016 | Pubmed ID: 27040190 Polygonatum Odoratum Lectin Induces Apoptosis and Autophagy by Regulation of MicroRNA-1290 and MicroRNA-15a-3p in Human Lung Adenocarcinoma A549 Cells International Journal of Biological Macromolecules. Apr, 2016 | Pubmed ID: 26562549 Human Eukaryotic Elongation Factor 1A Forms Oligomers Through Specific Cysteine Residues Acta Biochimica Et Biophysica Sinica. Dec, 2015 | Pubmed ID: 26515794 A Non-symmetric Pillar[5]arene Based on Triazole-linked 8-oxyquinolines As a Sequential Sensor for Thorium(IV) Followed by Fluoride Ions Dalton Transactions (Cambridge, England : 2003). Sep, 2015 | Pubmed ID: 25689727 Ditopic CMPO-pillar[5]arenes As Unique Receptors for Efficient Separation of Americium(III) and Europium(III) Chemical Communications (Cambridge, England). Mar, 2015 | Pubmed ID: 25671799 Pillar[5]arene-based Diglycolamides for Highly Efficient Separation of Americium(III) and Europium(III) Dalton Transactions (Cambridge, England : 2003). Mar, 2014 | Pubmed ID: 24434919 Anti-tumor and Anti-viral Activities of Galanthus Nivalis Agglutinin (GNA)-related Lectins Glycoconjugate Journal. Apr, 2013 | Pubmed ID: 22893111 Identification of CK2 Inhibitors with New Scaffolds by a Hybrid Virtual Screening Approach Based on Bayesian Model; Pharmacophore Hypothesis and Molecular Docking Journal of Molecular Graphics & Modelling. Jun, 2012 | Pubmed ID: 22516037 Combined SVM-based and Docking-based Virtual Screening for Retrieving Novel Inhibitors of C-Met European Journal of Medicinal Chemistry. Sep, 2011 | Pubmed ID: 21641696 Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues (Video) | JoVE Lin Bai1,2, Yaping Wu2, Wenshu Dai1, Qiuxiao Shi2, Lei Wu2, Jie Zhang1,2, Lily Zheng3 1Key Laboratory of Transplant Engineering and Immunology, NHFPC, West China Hospital, Sichuan University, 2Core Facility of West China Hospital, Sichuan University, 3Regenerative Medicine Research Center, West China Hospital, Sichuan University JoVE 65973 생물학
Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues (Video) | JoVE Lin Bai1,2, Yaping Wu2, Wenshu Dai1, Qiuxiao Shi2, Lei Wu2, Jie Zhang1,2, Lily Zheng3 1Key Laboratory of Transplant Engineering and Immunology, NHFPC, West China Hospital, Sichuan University, 2Core Facility of West China Hospital, Sichuan University, 3Regenerative Medicine Research Center, West China Hospital, Sichuan University JoVE 65973 생물학