Lingfeng Qin Department of Surgery Yale University School of Medicine Biography Publications Institution JoVE Articles Lingfeng Qin has not added a biography. If you are Lingfeng Qin and would like to personalize this page please email our Author Liaison for assistance. Publications FGFR1 SUMOylation Coordinates Endothelial Angiogenic Signaling in Angiogenesis Proceedings of the National Academy of Sciences of the United States of America. 06, 2022 | Pubmed ID: 35733256 Readily Available Tissue-Engineered Vascular Grafts Derived From Human Induced Pluripotent Stem Cells Circulation Research. 03, 2022 | Pubmed ID: 35189711 Hexarelin Attenuates Abdominal Aortic Aneurysm Formation by Inhibiting SMC Phenotype Switch and Inflammasome Activation Microvascular Research. 03, 2022 | Pubmed ID: 34856183 CCM3 Loss-Induced Lymphatic Defect Is Mediated by the Augmented VEGFR3-ERK1/2 Signaling Arteriosclerosis, Thrombosis, and Vascular Biology. 12, 2021 | Pubmed ID: 34670407 Caveolae-mediated Tie2 Signaling Contributes to CCM Pathogenesis in a Brain Endothelial Cell-specific Pdcd10-deficient Mouse Model Nature Communications. 01, 2021 | Pubmed ID: 33495460 H19/TET1 Axis Promotes TGF-β Signaling Linked to Endothelial-to-mesenchymal Transition FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 06, 2020 | Pubmed ID: 32374060 Smooth Muscle Cell Reprogramming in Aortic Aneurysms Cell Stem Cell. 04, 2020 | Pubmed ID: 32243809 Complement-activated Interferon-γ-primed Human Endothelium Transpresents Interleukin-15 to CD8+ T Cells The Journal of Clinical Investigation. 07, 2020 | Pubmed ID: 32191642 Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human IPSCs Cell Stem Cell. 02, 2020 | Pubmed ID: 31956039 Endothelial Cell-Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production Circulation. 02, 2020 | Pubmed ID: 31744330 Endothelial TGF-β Signalling Drives Vascular Inflammation and Atherosclerosis Nature Metabolism. 09, 2019 | Pubmed ID: 31572976 Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-γ-Primed Human Endothelium Circulation Research. 06, 2019 | Pubmed ID: 31170059 ZFYVE21 is a Complement-induced Rab5 Effector That Activates Non-canonical NF-κB Via Phosphoinosotide Remodeling of Endosomes Nature Communications. 05, 2019 | Pubmed ID: 31113953 AIP1 Suppresses Transplant Arteriosclerosis Through Inhibition of Vascular Smooth Muscle Cell Inflammatory Response to IFNγ Anatomical Record (Hoboken, N.J. : 2007). 09, 2019 | Pubmed ID: 30471213 Integrin Beta3 Regulates Clonality and Fate of Smooth Muscle-derived Atherosclerotic Plaque Cells Nature Communications. 05, 2018 | Pubmed ID: 29802249 Vascular Smooth Muscle Cells Derived from Inbred Swine Induced Pluripotent Stem Cells for Vascular Tissue Engineering Biomaterials. Dec, 2017 | Pubmed ID: 28942128 Ex Vivo Pretreatment of Human Vessels with SiRNA Nanoparticles Provides Protein Silencing in Endothelial Cells Nature Communications. 08, 2017 | Pubmed ID: 28775323 SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling Circulation Research. Sep, 2017 | Pubmed ID: 28760777 MTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2017 | Pubmed ID: 28751568 Improving In vivo Outcomes of Decellularized Vascular Grafts Via Incorporation of a Novel Extracellular Matrix Biomaterials. Oct, 2017 | Pubmed ID: 28667900 The Critical Role of SENP1-mediated GATA2 DeSUMOylation in Promoting Endothelial Activation in Graft Arteriosclerosis Nature Communications. 06, 2017 | Pubmed ID: 28569748 Deficient Circumferential Growth Is the Primary Determinant of Aortic Obstruction Attributable to Partial Elastin Deficiency Arteriosclerosis, Thrombosis, and Vascular Biology. 05, 2017 | Pubmed ID: 28254817 Inhibition of the MTOR Pathway in Abdominal Aortic Aneurysm: Implications of Smooth Muscle Cell Contractile Phenotype, Inflammation, and Aneurysm Expansion American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2017 | Pubmed ID: 28213405 Fibroblast Growth Factor (FGF) Signaling Regulates Transforming Growth Factor Beta (TGFβ)-dependent Smooth Muscle Cell Phenotype Modulation Scientific Reports. 09, 2016 | Pubmed ID: 27634335 Endothelial Exocytosis of Angiopoietin-2 Resulting from CCM3 Deficiency Contributes to Cerebral Cavernous Malformation Nature Medicine. 09, 2016 | Pubmed ID: 27548575 Implantable Tissue-engineered Blood Vessels from Human Induced Pluripotent Stem Cells Biomaterials. Sep, 2016 | Pubmed ID: 27336184 Smooth Muscle FGF/TGFβ Cross Talk Regulates Atherosclerosis Progression EMBO Molecular Medicine. 07, 2016 | Pubmed ID: 27189169 Blocking MHC Class II on Human Endothelium Mitigates Acute Rejection JCI Insight. 2016 | Pubmed ID: 26900601 SENP1-mediated NEMO DeSUMOylation in Adipocytes Limits Inflammatory Responses and Type-1 Diabetes Progression Nature Communications. Nov, 2015 | Pubmed ID: 26596471 Endothelial-to-mesenchymal Transition Drives Atherosclerosis Progression The Journal of Clinical Investigation. Oct, 2015 | Pubmed ID: 26517696 Interferon-γ-mediated Allograft Rejection Exacerbates Cardiovascular Disease of Hyperlipidemic Murine Transplant Recipients Circulation Research. Nov, 2015 | Pubmed ID: 26399469 Complement Membrane Attack Complexes Activate Noncanonical NF-κB by Forming an Akt+ NIK+ Signalosome on Rab5+ Endosomes Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26195760 Fibroblast Growth Factor Receptor 1 is a Key Inhibitor of TGFβ Signaling in the Endothelium Science Signaling. Sep, 2014 | Pubmed ID: 25249657 Interacting Mechanisms in the Pathogenesis of Cardiac Allograft Vasculopathy Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2014 | Pubmed ID: 24903097 The Docking Protein FRS2α is a Critical Regulator of VEGF Receptors Signaling Proceedings of the National Academy of Sciences of the United States of America. Apr, 2014 | Pubmed ID: 24706887 Rapamycin Antagonizes TNF Induction of VCAM-1 on Endothelial Cells by Inhibiting MTORC2 The Journal of Experimental Medicine. Mar, 2014 | Pubmed ID: 24516119 Tgfbr2 Disruption in Postnatal Smooth Muscle Impairs Aortic Wall Homeostasis The Journal of Clinical Investigation. Feb, 2014 | Pubmed ID: 24401272 SOCS1 Prevents Graft Arteriosclerosis by Preserving Endothelial Cell Function Journal of the American College of Cardiology. Jan 7-14, 2014 | Pubmed ID: 23994402 Rapamicina Inibisce La Proliferazione Delle Cellule Muscolari Lisce E Arteriopatia Ostruttiva Attribuibile a Deficit Di Elastina Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2013 | Pubmed ID: 23493289 Cellule Endoteliali Umane Trattate Con Rapamicina Attivano Preferenzialmente Allogeniche Cellule T Regolatorie The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23478407 AIP1 Sopprime L'aterosclerosi, Limitando L'infiammazione Indotta Da Iperlipidemia E Disfunzione Endoteliale Vascolare Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2013 | Pubmed ID: 23413429 FGF Regola La Transizione Endotelio Mesenchimale E Segnalazione Di TGF-β Tramite Controllo Di Espressione Di MiRNA Let-7 Cell Reports. Dec, 2012 | Pubmed ID: 23200853 Attivazione Di Cellule Vascolari Diminuisce La Loro Espressione Di Transforming Growth Factor-beta Atherosclerosis. Dec, 2011 | Pubmed ID: 21862019 Transforming Growth Factor Beta Expression by Human Vascular Cells Inhibits Interferon Gamma Production and Arterial Media Injury by Alloreactive Memory T Cells American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2011 | Pubmed ID: 21812925 AIP1 Impedisce L'innesto Arteriosclerosi Inibendo La Proliferazione Delle Cellule Muscolari Lisce Di Interferone-γ-dipendente Ed Espansione Intimale Circulation Research. Aug, 2011 | Pubmed ID: 21700930 Accumulo CXCR3-dipendente E L'attivazione Dei Macrofagi Perivascolari è Necessario Rimodellamento Arterioso Omeostatica a Stress Emodinamico The Journal of Experimental Medicine. Aug, 2010 | Pubmed ID: 20733031 Sonic Hedgehog Signaling Induce La Proliferazione Delle Cellule Muscolari Lisce Vascolari Tramite Induzione Dell'asse G1 Cyclin-retinoblastoma Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2010 | Pubmed ID: 20720195 IFN-gamma Primes Umani Coronarie Indenni E Cellule Coltivate Muscolo Liscio Coronarico a Risposte Infiammatorie Double-stranded RNA - E Auto-RNA-induced by Upregulating TLR3 E Melanoma Differenziazione-associated Gene 5 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010 | Pubmed ID: 20562257 JAK2 E SHP2 Reciprocamente Regolano La Fosforilazione Della Tirosina E Stabilità Della Proteina Miselli ASK1 The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19287004 Interleuchina (IL) -1 Promuove Infiltrazione Intimale Allogenici Di Cellule T E La Produzione Di IL-17 in Un Modello Di Rifiuto Umano Dell'arteria The Journal of Experimental Medicine. Dec, 2008 | Pubmed ID: 19075290 MyD88-dipendente, Avviate Dal Superossido Infiammazione è Necessario Flusso-mediata Verso L'interno Rimodellamento Delle Arterie Conduit The Journal of Experimental Medicine. Dec, 2008 | Pubmed ID: 19064699 Induzione Di Indoleamine 2,3-diossigenasi Nelle Cellule Muscolari Lisce Vascolari Di Interferone-gamma Contribuisce Alla Immunoprivilege Mediale Journal of Immunology (Baltimore, Md. : 1950). Oct, 2007 | Pubmed ID: 17911610 Interferone Gamma Induce Proliferazione Cellulare Umana Muscolatura Liscia Vascolare Ed Espansione Intimale Fosfatidilinositolo 3-chinasi Dipendente Mammalian Target Di Rapamicina Complesso 1 Attivazione Di Raptor Circulation Research. Sep, 2007 | Pubmed ID: 17656678 Dosaggio multiplo in bolo endovenoso e valutazione emodinamica invasiva in un modello murino di ipertensione arteriosa polmonare indotta da ipossia Lingfeng Qin1, Bo Jiang2, Krisztina Zsebo3, Henricus J. Duckers3, Michael Simons4,5, Pei-Yu Chen4 1Department of Surgery, Yale University School of Medicine, 2Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention, and Therapeutics of Aortic Aneurysm, 3VasoRx Inc., 4Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, 5Department of Cell Biology, Yale University School of Medicine JoVE 63839 의학 Imaging e analisi delle lesioni dell'aorta intera O-macchiata di olio rosso in un modello murino di iperlipidemia da aneurisma Pei-Yu Chen1, Lingfeng Qin2, Michael Simons1,3 1Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, 2Department of Surgery, Yale University School of Medicine, 3Department of Cell Biology, Yale University School of Medicine JoVE 61277 의학 Modelli murini per l'arteriosclerosi Graft Lingfeng Qin1, Luyang Yu2, Wang Min2 1Department of Surgery, Yale University School of Medicine, 2Department of Pathology, Yale University School of Medicine JoVE 50290 의학
Dosaggio multiplo in bolo endovenoso e valutazione emodinamica invasiva in un modello murino di ipertensione arteriosa polmonare indotta da ipossia Lingfeng Qin1, Bo Jiang2, Krisztina Zsebo3, Henricus J. Duckers3, Michael Simons4,5, Pei-Yu Chen4 1Department of Surgery, Yale University School of Medicine, 2Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention, and Therapeutics of Aortic Aneurysm, 3VasoRx Inc., 4Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, 5Department of Cell Biology, Yale University School of Medicine JoVE 63839 의학
Imaging e analisi delle lesioni dell'aorta intera O-macchiata di olio rosso in un modello murino di iperlipidemia da aneurisma Pei-Yu Chen1, Lingfeng Qin2, Michael Simons1,3 1Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, 2Department of Surgery, Yale University School of Medicine, 3Department of Cell Biology, Yale University School of Medicine JoVE 61277 의학
Modelli murini per l'arteriosclerosi Graft Lingfeng Qin1, Luyang Yu2, Wang Min2 1Department of Surgery, Yale University School of Medicine, 2Department of Pathology, Yale University School of Medicine JoVE 50290 의학