Marc Bracke Department of Radiation Oncology and Experimental Cancer Research Ghent University Biography Publications Institution JoVE Articles Marc Bracke has not added a biography. If you are Marc Bracke and would like to personalize this page please email our Author Liaison for assistance. Publications Selective Modulation of the Glucocorticoid Receptor Can Distinguish Between Transrepression of NF-κB and AP-1 Cellular and Molecular Life Sciences : CMLS. Jun, 2013 | Pubmed ID: 23784308 Radiation-induced Myosin IIA Expression Stimulates Collagen Type I Matrix Reorganization Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Jun, 2013 | Pubmed ID: 23742963 Targeted Liposome-Loaded Microbubbles for Cell-Specific Ultrasound-Triggered Drug Delivery Small (Weinheim an Der Bergstrasse, Germany). Jun, 2013 | Pubmed ID: 23737360 Unraveling the Mechanisms Behind the Enhanced MTT Conversion by Irradiated Breast Cancer Cells Radiation Research. Apr, 2013 | Pubmed ID: 23465060 Vacuolar H+ ATPase Expression and Activity is Required for Rab27B-dependent Invasive Growth and Metastasis of Breast Cancer International Journal of Cancer. Journal International Du Cancer. Aug, 2013 | Pubmed ID: 23390068 Frondoside a Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis PloS One. 2013 | Pubmed ID: 23308143 Differential Secretome Analysis of Cancer-associated Fibroblasts and Bone Marrow-derived Precursors to Identify Microenvironmental Regulators of Colon Cancer Progression Proteomics. Jan, 2013 | Pubmed ID: 23175172 ER Stress in Diffuse Large B Cell Lymphoma: GRP94 is a Possible Biomarker in Germinal Center Versus Activated B-cell Type Leukemia Research. Jan, 2013 | Pubmed ID: 22938940 Bone Marrow-derived Mesenchymal Stem Cells Promote Colorectal Cancer Progression Through Paracrine Neuregulin 1/HER3 Signalling Gut. Apr, 2013 | Pubmed ID: 22535374 An Immobilized Antibody Targeting N-cadherin Facilitates Spread of N-cadherin-positive Tumour Cells Anticancer Research. Nov, 2012 | Pubmed ID: 23155239 Prenylated Chalcone Xanthohumol Associates with Histones in Breast Cancer Cells--a Novel Target Identified by a Monoclonal Antibody Molecular Nutrition & Food Research. Nov, 2012 | Pubmed ID: 23001824 Tumor Grafts Derived from Sarcoma Patients Retain Tumor Morphology, Viability, and Invasion Potential and Indicate Disease Outcomes in the Chick Chorioallantoic Membrane Model Cancer Letters. Dec, 2012 | Pubmed ID: 22841668 An Immunohistochemical Analysis of Rab27B Distribution in Fetal and Adult Tissue The International Journal of Developmental Biology. 2012 | Pubmed ID: 22811270 Exploration of the SAR of Anti-invasive Chalcones: Synthesis and Biological Evaluation of Conformationally Restricted Analogues Bioorganic & Medicinal Chemistry. Aug, 2012 | Pubmed ID: 22743088 DNA Methylation-based Biomarkers in Serum of Patients with Breast Cancer Mutation Research. Oct-Dec, 2012 | Pubmed ID: 22698615 Development of a Nanocrystalline Paclitaxel Formulation for HIPEC Treatment Pharmaceutical Research. Sep, 2012 | Pubmed ID: 22555379 Identification of a GαGβγ, AKT and PKCα Signalome Associated with Invasive Growth in Two Genetic Models of Human Breast Cancer Cell Epithelial-to-mesenchymal Transition International Journal of Oncology. Jul, 2012 | Pubmed ID: 22552300 Angiopoietin-like Protein 4: Health Effects, Modulating Agents and Structure-function Relationships Expert Review of Proteomics. Apr, 2012 | Pubmed ID: 22462789 N-cadherin in Neuroblastoma Disease: Expression and Clinical Significance PloS One. 2012 | Pubmed ID: 22355346 The Role of Non-muscle Myosin IIA in Aggregation and Invasion of Human MCF-7 Breast Cancer Cells The International Journal of Developmental Biology. 2011 | Pubmed ID: 22161839 Developmental and Cancer Research on the Mammary Gland Nowadays The International Journal of Developmental Biology. 2011 | Pubmed ID: 22161823 Bioavailability of Hop-derived Iso-α-acids and Reduced Derivatives Food & Function. Jul, 2011 | Pubmed ID: 21894329 The Tumor Ecosystem Regulates the Roads for Invasion and Metastasis Clinics and Research in Hepatology and Gastroenterology. Nov, 2011 | Pubmed ID: 21676670 Production of Monoclonal Antibodies Against Hop-derived (Humulus Lupulus L.) Prenylflavonoids and the Development of Immunoassays Talanta. Jul, 2011 | Pubmed ID: 21645689 Priming and Potentiation of DNA Damage Response by Fibronectin in Human Colon Cancer Cells and Tumor-derived Myofibroblasts International Journal of Oncology. Aug, 2011 | Pubmed ID: 21567080 Bacterial Monocultures, Propionate, Butyrate and H2O2 Modulate the Expression, Secretion and Structure of the Fasting-induced Adipose Factor in Gut Epithelial Cell Lines Environmental Microbiology. Jul, 2011 | Pubmed ID: 21518214 P-cadherin Expression Reduces Melanoma Growth, Invasion, and Responsiveness to Growth Factors in Nude Mice European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). May, 2011 | Pubmed ID: 21445019 Adherence and Viability of Intestinal Bacteria to Differentiated Caco-2 Cells Quantified by Flow Cytometry Journal of Microbiological Methods. Jul, 2011 | Pubmed ID: 21443910 EGFR in Melanoma: Clinical Significance and Potential Therapeutic Target Journal of Cutaneous Pathology. Jun, 2011 | Pubmed ID: 21352258 Overall Welfare Assessment of Laying Hens: Comparing Science-based, Environment-based and Animal-based Assessments Animal Science Journal = Nihon Chikusan GakkaihÅ. Feb, 2011 | Pubmed ID: 21269374 Inhibition of Cell Survival, Invasion, Tumor Growth and Histone Deacetylase Activity by the Dietary Flavonoid Luteolin in Human Epithelioid Cancer Cells European Journal of Pharmacology. Jan, 2011 | Pubmed ID: 21074525 P-cadherin in Adhesion and Invasion: Opposite Roles in Colon and Bladder Carcinoma International Journal of Cancer. Journal International Du Cancer. Mar, 2011 | Pubmed ID: 20473917 The Secretory Small GTPase Rab27B As a Marker for Breast Cancer Progression Oncotarget. Aug, 2010 | Pubmed ID: 21304180 An Ex(o)citing Machinery for Invasive Tumor Growth Cancer Research. Dec, 2010 | Pubmed ID: 21098711 P-cadherin Counteracts Myosin II-B Function: Implications in Melanoma Progression Molecular Cancer. 2010 | Pubmed ID: 20860798 Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells Cancer Research. Oct, 2010 | Pubmed ID: 20841469 Disposition of Hop Prenylflavonoids in Human Breast Tissue Molecular Nutrition & Food Research. Jul, 2010 | Pubmed ID: 20486208 Effect of the Secretory Small GTPase Rab27B on Breast Cancer Growth, Invasion, and Metastasis Journal of the National Cancer Institute. Jun, 2010 | Pubmed ID: 20484105 Opioids Affect Focal Contact-mediated Cell-substrate Adhesion European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). May, 2010 | Pubmed ID: 20361424 Transport of Hop Bitter Acids Across Intestinal Caco-2 Cell Monolayers Journal of Agricultural and Food Chemistry. Apr, 2010 | Pubmed ID: 20329731 Resident and Bone Marrow-derived Mesenchymal Stem Cells in Head and Neck Squamous Cell Carcinoma Oral Oncology. May, 2010 | Pubmed ID: 20219413 From Clinical Observations of Intensity-modulated Radiotherapy to Dedicated in Vitro Designs Mutation Research. Apr-Jun, 2010 | Pubmed ID: 20178859 Disposition of Soy Isoflavones in Normal Human Breast Tissue The American Journal of Clinical Nutrition. Apr, 2010 | Pubmed ID: 20164315 Direct Effects of Delta Opioid Receptor Agonists on Invasion-associated Activities of HCT-8/E11 Colon Cancer Cells Anticancer Research. Jan, 2010 | Pubmed ID: 20150612 The Flavonoid Tangeretin Activates the Unfolded Protein Response and Synergizes with Imatinib in the Erythroleukemia Cell Line K562 Molecular Nutrition & Food Research. Jun, 2010 | Pubmed ID: 20077418 Modeling and Quantification of Cancer Cell Invasion Through Collagen Type I Matrices The International Journal of Developmental Biology. 2010 | Pubmed ID: 19757378 Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma with Wild-type P53 Journal of the National Cancer Institute. Nov, 2009 | Pubmed ID: 19903807 Cosupplementation of Isoflavones, Prenylflavonoids, and Lignans Alters Human Exposure to Phytoestrogen-derived 17beta-estradiol Equivalents The Journal of Nutrition. Dec, 2009 | Pubmed ID: 19864398 Xanthohumol Activates the Proapoptotic Arm of the Unfolded Protein Response in Chronic Lymphocytic Leukemia Anticancer Research. Oct, 2009 | Pubmed ID: 19846911 Down-regulation of Myopodin Expression Reduces Invasion and Motility of PC-3 Prostate Cancer Cells International Journal of Oncology. May, 2009 | Pubmed ID: 19360353 The Extracellular Matrix Regulates Cancer Progression and Therapy Response: Implications for Prognosis and Treatment Current Pharmaceutical Design. 2009 | Pubmed ID: 19355975 Steroid Effects on ZAP-70 and SYK in Relation to Apoptosis in Poor Prognosis Chronic Lymphocytic Leukemia Leukemia Research. Oct, 2009 | Pubmed ID: 19297020 Cell Aggregation on Agar As an Indicator for Cell-matrix Adhesion: Effects of Opioids In Vitro Cellular & Developmental Biology. Animal. Sep, 2009 | Pubmed ID: 19247723 Peritoneal Minimal Residual Disease in Colorectal Cancer: Mechanisms, Prevention, and Treatment The Lancet Oncology. Jan, 2009 | Pubmed ID: 19111247 TRIP6, a Novel Molecular Partner of the MAGI-1 Scaffolding Molecule, Promotes Invasiveness FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2009 | Pubmed ID: 19017743 Stromal Myofibroblasts Are Drivers of Invasive Cancer Growth International Journal of Cancer. Journal International Du Cancer. Nov, 2008 | Pubmed ID: 18777559 Molecular Signature and Therapeutic Perspective of the Epithelial-to-mesenchymal Transitions in Epithelial Cancers Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Aug-Oct, 2008 | Pubmed ID: 18718806 Molecular and Pathological Signatures of Epithelial-mesenchymal Transitions at the Cancer Invasion Front Histochemistry and Cell Biology. Sep, 2008 | Pubmed ID: 18648847 Expert Opinion As 'validation' of Risk Assessment Applied to Calf Welfare Acta Veterinaria Scandinavica. 2008 | Pubmed ID: 18625048 Pollutant Effects on Genotoxic Parameters and Tumor-associated Protein Levels in Adults: a Cross Sectional Study Environmental Health : a Global Access Science Source. 2008 | Pubmed ID: 18522717 Differential Impact of TGF-beta and EGF on Fibroblast Differentiation and Invasion Reciprocally Promotes Colon Cancer Cell Invasion Cancer Letters. Aug, 2008 | Pubmed ID: 18423981 The Microbial PhIP Metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium Chloride (PhIP-M1) Induces DNA Damage, Apoptosis and Cell Cycle Arrest Towards Caco-2 Cells Toxicology Letters. Apr, 2008 | Pubmed ID: 18375078 Enhancement of PDGF-BB Mitogenic Activity on Human Dermal Fibroblasts by Biospecific Dextran Derivatives Biomaterials. May, 2008 | Pubmed ID: 18276000 Role of WISP-2/CCN5 in the Maintenance of a Differentiated and Noninvasive Phenotype in Human Breast Cancer Cells Molecular and Cellular Biology. Feb, 2008 | Pubmed ID: 18070926 Soluble Cadherins As Cancer Biomarkers Clinical & Experimental Metastasis. 2007 | Pubmed ID: 17952616 Microbial and Dietary Factors Are Associated with the Equol Producer Phenotype in Healthy Postmenopausal Women The Journal of Nutrition. Oct, 2007 | Pubmed ID: 17885005 Estrogen Receptor Signaling is an Unstable Feature of the Gonadotropic LbetaT2 Cell Line Molecular and Cellular Endocrinology. Jul, 2007 | Pubmed ID: 17561339 Microbial and Dietary Factors Associated with the 8-prenylnaringenin Producer Phenotype: a Dietary Intervention Trial with Fifty Healthy Post-menopausal Caucasian Women The British Journal of Nutrition. Nov, 2007 | Pubmed ID: 17521469 Downregulation of Gelsolin Family Proteins Counteracts Cancer Cell Invasion in Vitro Cancer Letters. Sep, 2007 | Pubmed ID: 17493746 Estrogen Receptor Alpha (ERalpha) and Insulin-like Growth Factor I Receptor (IGF-IR) Cross-talk in the Gonadotropic AlphaT3-1 Cell Line Journal of Cellular Physiology. Sep, 2007 | Pubmed ID: 17458895 The Tandem PDZ Domains of Syntenin Promote Cell Invasion Experimental Cell Research. May, 2007 | Pubmed ID: 17451681 Review. The Endoplasmic Reticulum: a Target for New Anticancer Drugs In Vivo (Athens, Greece). Mar-Apr, 2007 | Pubmed ID: 17436569 Growth Factor Modulation of Fibroblast Proliferation, Differentiation, and Invasion: Implications for Tissue Valve Engineering Tissue Engineering. Oct, 2006 | Pubmed ID: 17518640 Anti-invasive/anti-metastasis Strategies: New Roads, New Tools and New Hopes Current Cancer Drug Targets. Dec, 2006 | Pubmed ID: 17168676 Soluble N-cadherin in Human Biological Fluids International Journal of Cancer. Journal International Du Cancer. Dec, 2006 | Pubmed ID: 16998833 QSAR Modeling of Anti-invasive Activity of Organic Compounds Using Structural Descriptors Bioorganic & Medicinal Chemistry. Oct, 2006 | Pubmed ID: 16908166 Differences in Tumor-associated Protein Levels Among Middle-age Flemish Women in Association with Area of Residence and Exposure to Pollutants Environmental Health Perspectives. Jun, 2006 | Pubmed ID: 16759990 Colon Cancer Cells: Pro-invasive Signalling The International Journal of Biochemistry & Cell Biology. 2006 | Pubmed ID: 16513408 A First Prospective, Randomized, Double-blind, Placebo-controlled Study on the Use of a Standardized Hop Extract to Alleviate Menopausal Discomforts Maturitas. May, 2006 | Pubmed ID: 16321485 Molecular Targets of Growth, Differentiation, Tissue Integrity, and Ectopic Cell Death in Cancer Cells Cancer Biotherapy & Radiopharmaceuticals. Dec, 2005 | Pubmed ID: 16398610 P-cadherin Promotes Cell-cell Adhesion and Counteracts Invasion in Human Melanoma Cancer Research. Oct, 2005 | Pubmed ID: 16204047 Nerve Growth Factor Mediates Its Pro-invasive Effect in Parallel with the Release of a Soluble E-cadherin Fragment from Breast Cancer MCF-7/AZ Cells The Journal of Dairy Research. 2005 | Pubmed ID: 16180717 Xanthohumol Kills B-chronic Lymphocytic Leukemia Cells by an Apoptotic Mechanism Molecular Nutrition & Food Research. Sep, 2005 | Pubmed ID: 16144030 Commutators of PAR-1 Signaling in Cancer Cell Invasion Reveal an Essential Role of the Rho-Rho Kinase Axis and Tumor Microenvironment Oncogene. Dec, 2005 | Pubmed ID: 16091733 Antiinvasive Effect of Xanthohumol, a Prenylated Chalcone Present in Hops (Humulus Lupulus L.) and Beer International Journal of Cancer. Journal International Du Cancer. Dec, 2005 | Pubmed ID: 15986430 Unrecognized or Potential Risk Factors for Childhood Cancer International Journal of Occupational and Environmental Health. Apr-Jun, 2005 | Pubmed ID: 15875896 A Safety Study of Oral Tangeretin and Xanthohumol Administration to Laboratory Mice In Vivo (Athens, Greece). Jan-Feb, 2005 | Pubmed ID: 15796161 Tangeretin Inhibits Extracellular-signal-regulated Kinase (ERK) Phosphorylation FEBS Letters. Mar, 2005 | Pubmed ID: 15757658 The Cancer Chemopreventive Agent Resveratrol Induces Tensin, a Cell-matrix Adhesion Protein with Signaling and Antitumor Activities Oncogene. May, 2005 | Pubmed ID: 15735708 Implication of STAT3 Signaling in Human Colonic Cancer Cells During Intestinal Trefoil Factor 3 (TFF3) -- and Vascular Endothelial Growth Factor-mediated Cellular Invasion and Tumor Growth Cancer Research. Jan, 2005 | Pubmed ID: 15665295 Bowes Melanoma Cells Secrete Heregulin, Which Can Promote Aggregation and Counteract Invasion of Human Mammary Cancer Cells International Journal of Cancer. Journal International Du Cancer. Apr, 2005 | Pubmed ID: 15609326 Roles for Neuregulins in Human Cancer Clinical & Experimental Metastasis. 2004 | Pubmed ID: 16035612 P-cadherin is Up-regulated by the Antiestrogen ICI 182,780 and Promotes Invasion of Human Breast Cancer Cells Cancer Research. Nov, 2004 | Pubmed ID: 15548699 N-cadherin in the Spotlight of Cell-cell Adhesion, Differentiation, Embryogenesis, Invasion and Signalling The International Journal of Developmental Biology. 2004 | Pubmed ID: 15349821 Critical Role of N-cadherin in Myofibroblast Invasion and Migration in Vitro Stimulated by Colon-cancer-cell-derived TGF-beta or Wounding Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331629 Dual Activities of Galectin-3 in Human Prostate Cancer: Tumor Suppression of Nuclear Galectin-3 Vs Tumor Promotion of Cytoplasmic Galectin-3 Oncogene. Sep, 2004 | Pubmed ID: 15326483 Distribution of Soy-derived Phytoestrogens in Human Breast Tissue and Biological Fluids Obstetrics and Gynecology. May, 2004 | Pubmed ID: 15121562 Melanoma Cells Secrete Follistatin, an Antagonist of Activin-mediated Growth Inhibition Oncogene. Jul, 2004 | Pubmed ID: 15064726 Tenascin-C and SF/HGF Produced by Myofibroblasts in Vitro Provide Convergent Pro-invasive Signals to Human Colon Cancer Cells Through RhoA and Rac FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2004 | Pubmed ID: 15059978 Alpha-catenin is Required for IGF-I-induced Cellular Migration but Not Invasion in Human Colonic Cancer Cells Oncogene. Feb, 2004 | Pubmed ID: 14961074 The Heregulin/human Epidermal Growth Factor Receptor As a New Growth Factor System in Melanoma with Multiple Ways of Deregulation The Journal of Investigative Dermatology. Oct, 2003 | Pubmed ID: 14632199 Synthesis, Characterization and in Vitro Anti-invasive Activity Screening of Polyphenolic and Heterocyclic Compounds Bioorganic & Medicinal Chemistry. Mar, 2003 | Pubmed ID: 12614877 Quantitation of Soy-derived Phytoestrogens in Human Breast Tissue and Biological Fluids by High-performance Liquid Chromatography Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Jan, 2003 | Pubmed ID: 12504192 Role of the IGF-I Receptor in the Regulation of Cell-cell Adhesion: Implications in Cancer Development and Progression Journal of Cellular Physiology. Feb, 2003 | Pubmed ID: 12494449 Plasmin Produces an E-cadherin Fragment That Stimulates Cancer Cell Invasion Biological Chemistry. Jan, 2002 | Pubmed ID: 11928810 The In ovo CAM-assay as a Xenograft Model for Sarcoma Gwen M.L. Sys1, Lore Lapeire2, Nikita Stevens1, Herman Favoreel3, Ramses Forsyth4, Marc Bracke2, Olivier De Wever2 1Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, 2Department of Radiation Oncology and Experimental Cancer Research, Ghent University, 3Department of Virology, Parasitology, and Immunology, Ghent University, 4Pathlicon JoVE 50522 의학
The In ovo CAM-assay as a Xenograft Model for Sarcoma Gwen M.L. Sys1, Lore Lapeire2, Nikita Stevens1, Herman Favoreel3, Ramses Forsyth4, Marc Bracke2, Olivier De Wever2 1Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, 2Department of Radiation Oncology and Experimental Cancer Research, Ghent University, 3Department of Virology, Parasitology, and Immunology, Ghent University, 4Pathlicon JoVE 50522 의학