Mark W. Dewhirst Department of Radiation Oncology Duke University Medical Center Biography Publications Institution JoVE Articles Mark W. Dewhirst has not added a biography. If you are Mark W. Dewhirst and would like to personalize this page please email our Author Liaison for assistance. Publications Radioprotection of the Brain White Matter by Mn(III) N-butoxyethylpyridylporphyrin-based Superoxide Dismutase Mimic, MnTnBuOE-2-PyP5+ Molecular Cancer Therapeutics. Oct, 2014 | Pubmed ID: 25319393 Systemic Anti-tumour Effects of Local Thermally Sensitive Liposome Therapy International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2014 | Pubmed ID: 25164143 Two Phase I Dose-escalation/pharmacokinetics Studies of Low Temperature Liposomal Doxorubicin (LTLD) and Mild Local Hyperthermia in Heavily Pretreated Patients with Local Regionally Recurrent Breast Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Aug, 2014 | Pubmed ID: 25144817 Verification of a Novel Method for Tube Voltage Constancy Measurement of Orthovoltage X-ray Irradiators Medical Physics. Aug, 2014 | Pubmed ID: 25086562 Comparison of the Hypoxia PET Tracer 18F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2014 | Pubmed ID: 24854792 Linking the History of Radiation Biology to the Hallmarks of Cancer Radiation Research. Jun, 2014 | Pubmed ID: 24811865 The Additive Damage Model: a Mathematical Model for Cellular Responses to Drug Combinations Journal of Theoretical Biology. Sep, 2014 | Pubmed ID: 24799130 Thermal Dosimetry Characteristics of Deep Regional Heating of Non-muscle Invasive Bladder Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2014 | Pubmed ID: 24669804 Targeting N-cadherin Increases Vascular Permeability and Differentially Activates AKT in Melanoma Annals of Surgery. Mar, 2014 | Pubmed ID: 24646553 Therapeutic Properties of Aerobic Training After a Cancer Diagnosis: More Than a One-trick Pony? Journal of the National Cancer Institute. Apr, 2014 | Pubmed ID: 24627274 Toward an Organ Based Dose Prescription Method for the Improved Accuracy of Murine Dose in Orthovoltage X-ray Irradiators Medical Physics. Mar, 2014 | Pubmed ID: 24593746 A Pilot Clinical Trial of Intravesical Mitomycin-C and External Deep Pelvic Hyperthermia for Non-muscle-invasive Bladder Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2014 | Pubmed ID: 24490762 Rationalization of Thermal Injury Quantification Methods: Application to Skin Burns Burns : Journal of the International Society for Burn Injuries. Aug, 2014 | Pubmed ID: 24418648 Imaging Tumor Hypoxia to Advance Radiation Oncology Antioxidants & Redox Signaling. Jul, 2014 | Pubmed ID: 24329000 Hypoxia in Melanoma: Using Optical Spectroscopy and EF5 to Assess Tumor Oxygenation Before and During Regional Chemotherapy for Melanoma Annals of Surgical Oncology. May, 2014 | Pubmed ID: 23982250 Measuring Tumor Cycling Hypoxia and Angiogenesis Using a Side-firing Fiber Optic Probe Journal of Biophotonics. Jul, 2014 | Pubmed ID: 23242854 Temperature Matters! And Why It Should Matter to Tumor Immunologists Cancer Immunology Research. Oct, 2013 | Pubmed ID: 24490177 Delivery Rate Affects Uptake of a Fluorescent Glucose Analog in Murine Metastatic Breast Cancer PloS One. 2013 | Pubmed ID: 24204635 PET with 62Cu-ATSM and 62Cu-PTSM is a Useful Imaging Tool for Hypoxia and Perfusion in Pulmonary Lesions AJR. American Journal of Roentgenology. Nov, 2013 | Pubmed ID: 24147499 Catabolism of Exogenous Lactate Reveals It As a Legitimate Metabolic Substrate in Breast Cancer PloS One. 2013 | Pubmed ID: 24069390 Magnetic Fluid Hyperthermia for Bladder Cancer: a Preclinical Dosimetry Study International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Dec, 2013 | Pubmed ID: 24050253 Understanding the Tumor Microenvironment and Radioresistance by Combining Functional Imaging with Global Gene Expression Seminars in Radiation Oncology. Oct, 2013 | Pubmed ID: 24012344 Introduction: Tumor As an Organ Seminars in Radiation Oncology. Oct, 2013 | Pubmed ID: 24012336 Tumor Cells Upregulate Normoxic HIF-1α in Response to Doxorubicin Cancer Research. Oct, 2013 | Pubmed ID: 23959856 A Method to Convert MRI Images of Temperature Change into Images of Absolute Temperature in Solid Tumours International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2013 | Pubmed ID: 23957326 Actively Targeting Solid Tumours with Thermoresponsive Drug Delivery Systems That Respond to Mild Hyperthermia International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2013 | Pubmed ID: 23924317 A Role for the Copper Transporter Ctr1 in the Synergistic Interaction Between Hyperthermia and Cisplatin Treatment International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2013 | Pubmed ID: 23879689 Modulation of Circulating Angiogenic Factors and Tumor Biology by Aerobic Training in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy Cancer Prevention Research (Philadelphia, Pa.). Sep, 2013 | Pubmed ID: 23842792 Preclinical Dosimetry of Magnetic Fluid Hyperthermia for Bladder Cancer Proceedings of SPIE. Feb, 2013 | Pubmed ID: 23837123 Quantitative Mapping of Hemodynamics in the Lung, Brain, and Dorsal Window Chamber-grown Tumors Using a Novel, Automated Algorithm Microcirculation (New York, N.Y. : 1994). Nov, 2013 | Pubmed ID: 23781901 18F-EF5 PET Imaging As an Early Response Biomarker for the Hypoxia-activated Prodrug SN30000 Combined with Radiation Treatment in a Non-small Cell Lung Cancer Xenograft Model Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2013 | Pubmed ID: 23740105 A Network of Substrates of the E3 Ubiquitin Ligases MDM2 and HUWE1 Control Apoptosis Independently of P53 Science Signaling. May, 2013 | Pubmed ID: 23652204 Novel Approaches to Treatment of Hepatocellular Carcinoma and Hepatic Metastases Using Thermal Ablation and Thermosensitive Liposomes Surgical Oncology Clinics of North America. Jul, 2013 | Pubmed ID: 23622079 Endothelial Colony Forming Cells (ECFCs) As a Model for Studying Effects of Low-dose Ionizing Radiation: Growth Inhibition by a Single Dose Cancer Investigation. Jun, 2013 | Pubmed ID: 23621632 Angiogenesis: an Adaptive Dynamic Biological Patterning Problem PLoS Computational Biology. 2013 | Pubmed ID: 23555218 CEM43°C Thermal Dose Thresholds: a Potential Guide for Magnetic Resonance Radiofrequency Exposure Levels? European Radiology. Aug, 2013 | Pubmed ID: 23553588 Radiation Induces Aerobic Glycolysis Through Reactive Oxygen Species Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Mar, 2013 | Pubmed ID: 23541363 The Impact of Temperature and Urinary Constituents on Urine Viscosity and Its Relevance to Bladder Hyperthermia Treatment International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2013 | Pubmed ID: 23489163 Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response PloS One. 2013 | Pubmed ID: 23326340 Resveratrol Worsens Survival in SCID Mice with Prostate Cancer Xenografts in a Cell-line Specific Manner, Through Paradoxical Effects on Oncogenic Pathways The Prostate. May, 2013 | Pubmed ID: 23192356 Effects and Potential Mechanisms of Exercise Training on Cancer Progression: a Translational Perspective Brain, Behavior, and Immunity. Mar, 2013 | Pubmed ID: 22610066 Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors Cancer Research. Nov, 2012 | Pubmed ID: 22952218 Thermal Dose Fractionation Affects Tumour Physiological Response International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 22804741 A Simplified Synthesis of the Hypoxia Imaging Agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[(18)F]pentafluoropropyl)-acetamide ([18F]EF5) Nuclear Medicine and Biology. Oct, 2012 | Pubmed ID: 22727821 High-resolution in Vivo Imaging of Fluorescent Proteins Using Window Chamber Models Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22700402 Miniature Microwave Applicator for Murine Bladder Hyperthermia Studies International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012 | Pubmed ID: 22690856 A Multi-institution Experience Comparing the Clinical and Physiologic Differences Between Upper Extremity and Lower Extremity Melphalan-based Isolated Limb Infusion Cancer. Dec, 2012 | Pubmed ID: 22674423 Exercise Modulation of the Host-tumor Interaction in an Orthotopic Model of Murine Prostate Cancer Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2012 | Pubmed ID: 22604887 Bevacizumab-induced Alterations in Vascular Permeability and Drug Delivery: a Novel Approach to Augment Regional Chemotherapy for In-transit Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2012 | Pubmed ID: 22496203 Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-induced HIF-1 Activation and Tumor Angiogenesis PloS One. 2012 | Pubmed ID: 22428047 Carbohydrate Restriction and Lactate Transporter Inhibition in a Mouse Xenograft Model of Human Prostate Cancer BJU International. Oct, 2012 | Pubmed ID: 22394625 Utility of Treatment Planning for Thermochemotherapy Treatment of Nonmuscle Invasive Bladder Carcinoma Medical Physics. Mar, 2012 | Pubmed ID: 22380348 Application of Optical Imaging and Spectroscopy to Radiation Biology Radiation Research. Apr, 2012 | Pubmed ID: 22360397 Introduction to the Special Issue on Molecular Imaging in Radiation Biology Radiation Research. Apr, 2012 | Pubmed ID: 22332930 Structural Adaptation of Normal and Tumour Vascular Networks Basic & Clinical Pharmacology & Toxicology. Jan, 2012 | Pubmed ID: 21995550 ErbB1/2 Tyrosine Kinase Inhibitor Mediates Oxidative Stress-induced Apoptosis in Inflammatory Breast Cancer Cells Breast Cancer Research and Treatment. Feb, 2012 | Pubmed ID: 21559822 Design of Mn Porphyrins for Treating Oxidative Stress Injuries and Their Redox-based Regulation of Cellular Transcriptional Activities Amino Acids. Jan, 2012 | Pubmed ID: 20473774 Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer The Open Nanomedicine Journal. Jan, 2011 | Pubmed ID: 23807899 IL-6 Trans-signaling Licenses Mouse and Human Tumor Microvascular Gateways for Trafficking of Cytotoxic T Cells The Journal of Clinical Investigation. Oct, 2011 | Pubmed ID: 21926464 In Vivo Optical Molecular Imaging and Analysis in Mice Using Dorsal Window Chamber Models Applied to Hypoxia, Vasculature and Fluorescent Reporters Nature Protocols. Sep, 2011 | Pubmed ID: 21886101 Cytotoxic Effects of Mn(III) N-alkylpyridylporphyrins in the Presence of Cellular Reductant, Ascorbate Free Radical Research. Nov, 2011 | Pubmed ID: 21859376 In Vivo Tumor Targeting by a NGR-decorated Micelle of a Recombinant Diblock Copolypeptide Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2011 | Pubmed ID: 21763734 Analysis of Tumor Environmental Response and Oncogenic Pathway Activation Identifies Distinct Basal and Luminal Features in HER2-related Breast Tumor Subtypes Breast Cancer Research : BCR. 2011 | Pubmed ID: 21672245 Diverse Functions of Cationic Mn(III) N-substituted Pyridylporphyrins, Recognized As SOD Mimics Free Radical Biology & Medicine. Sep, 2011 | Pubmed ID: 21616142 Thresholds for Thermal Damage to Normal Tissues: an Update International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2011 | Pubmed ID: 21591897 Formulation and Characterisation of Magnetic Resonance Imageable Thermally Sensitive Liposomes for Use with Magnetic Resonance-guided High Intensity Focused Ultrasound International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2011 | Pubmed ID: 21314334 Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2011 | Pubmed ID: 21292819 Cellular Redox Modulator, Ortho Mn(III) Meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the Treatment of Brain Tumors Anti-cancer Agents in Medicinal Chemistry. Feb, 2011 | Pubmed ID: 21291403 Molecular Imaging of Hypoxia Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2011 | Pubmed ID: 21233176 Bioavailability of Metalloporphyrin-based SOD Mimics is Greatly Influenced by a Single Charge Residing on a Mn Site Free Radical Research. Feb, 2011 | Pubmed ID: 20942564 Individual Responses to Chemotherapy-induced Oxidative Stress Breast Cancer Research and Treatment. Jan, 2011 | Pubmed ID: 20830514 Optical Imaging of Tumor Hypoxia Dynamics Journal of Biomedical Optics. Nov-Dec, 2010 | Pubmed ID: 21198195 Durable Palliation of Breast Cancer Chest Wall Recurrence with Radiation Therapy, Hyperthermia, and Chemotherapy Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Dec, 2010 | Pubmed ID: 21074876 NADPH Oxidase-mediated Reactive Oxygen Species Production Activates Hypoxia-inducible Factor-1 (HIF-1) Via the ERK Pathway After Hyperthermia Treatment Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21059928 Magnetic Resonance Imaging: a Potential Tool in Assessing the Addition of Hyperthermia to Neoadjuvant Therapy in Patients with Locally Advanced Breast Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20849258 Hyperthermia for Locally Advanced Breast Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20849257 Hyperthermia Combined with Radiation Therapy for Superficial Breast Cancer and Chest Wall Recurrence: a Review of the Randomised Data International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20849256 Novel MRI and Fluorescent Probes Responsive to the Factor XIII Transglutaminase Activity Contrast Media & Molecular Imaging. Jul-Aug, 2010 | Pubmed ID: 20812289 Low-carbohydrate Diets and Prostate Cancer: How Low is "low Enough"? Cancer Prevention Research (Philadelphia, Pa.). Sep, 2010 | Pubmed ID: 20716631 Stereocomplexed Poly(lactic Acid)-poly(ethylene Glycol) Nanoparticles with Dual-emissive Boron Dyes for Tumor Accumulation ACS Nano. Sep, 2010 | Pubmed ID: 20704337 A Feasibility Study Using Radiochromic Films for Fast Neutron 2D Passive Dosimetry Physics in Medicine and Biology. Sep, 2010 | Pubmed ID: 20693612 The Shunt Problem: Control of Functional Shunting in Normal and Tumour Vasculature Nature Reviews. Cancer. Aug, 2010 | Pubmed ID: 20631803 Comparative Effects of Thermosensitive Doxorubicin-containing Liposomes and Hyperthermia in Human and Murine Tumours International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20597627 Effect of Pazopanib on Tumor Microenvironment and Liposome Delivery Molecular Cancer Therapeutics. Jun, 2010 | Pubmed ID: 20515941 Effective Learning Strategies for Real-time Image-guided Adaptive Control of Multiple-source Hyperthermia Applicators Medical Physics. Mar, 2010 | Pubmed ID: 20384266 Mathematical Formulation and Analysis of the Nonlinear System Reconstruction of the Online Image-guided Adaptive Control of Hyperthermia Medical Physics. Mar, 2010 | Pubmed ID: 20384234 A Phase I/II Study of Neoadjuvant Liposomal Doxorubicin, Paclitaxel, and Hyperthermia in Locally Advanced Breast Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20377362 Application of Mixed Spin IMQCs for Temperature and Chemical-selective Imaging Journal of Magnetic Resonance (San Diego, Calif. : 1997). Jun, 2010 | Pubmed ID: 20303808 Longitudinal Optical Imaging of Tumor Metabolism and Hemodynamics Journal of Biomedical Optics. Jan-Feb, 2010 | Pubmed ID: 20210438 Utility of Functional Imaging in Prediction or Assessment of Treatment Response and Prognosis Following Thermotherapy International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2010 | Pubmed ID: 20170362 Tumor Metabolism of Lactate: the Influence and Therapeutic Potential for MCT and CD147 Regulation Future Oncology (London, England). Jan, 2010 | Pubmed ID: 20021214 Effect of Aerobic Exercise on Tumor Physiology in an Animal Model of Human Breast Cancer Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2010 | Pubmed ID: 19959769 Non-invasive Monitoring of Intra-tumor Drug Concentration and Therapeutic Response Using Optical Spectroscopy Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2010 | Pubmed ID: 19896999 Phosphorylated Epidermal Growth Factor Receptor and Cyclooxygenase-2 Expression in Localized Non-small Cell Lung Cancer Medical Oncology (Northwood, London, England). Mar, 2010 | Pubmed ID: 19235531 Control Time Reduction Using Virtual Source Projection for Treating a Leg Sarcoma with Nonlinear Perfusion Proceedings of SPIE. Feb, 2009 | Pubmed ID: 24392195 Accuracy of Real Time Noninvasive Temperature Measurements Using Magnetic Resonance Thermal Imaging in Patients Treated for High Grade Extremity Soft Tissue Sarcomas Medical Physics. Nov, 2009 | Pubmed ID: 19994492 Relationships Between Cycling Hypoxia, HIF-1, Angiogenesis and Oxidative Stress Radiation Research. Dec, 2009 | Pubmed ID: 19929412 Quantitative Optical Spectroscopy Can Identify Long-term Local Tumor Control in Irradiated Murine Head and Neck Xenografts Journal of Biomedical Optics. Sep-Oct, 2009 | Pubmed ID: 19895152 Using Optical Spectroscopy to Longitudinally Monitor Physiological Changes Within Solid Tumors Neoplasia (New York, N.Y.). Sep, 2009 | Pubmed ID: 19724683 A Dual-emissive-materials Design Concept Enables Tumour Hypoxia Imaging Nature Materials. Sep, 2009 | Pubmed ID: 19668206 Characterization of a 137Cs Irradiator from a New Perspective with Modern Dosimetric Tools Health Physics. Sep, 2009 | Pubmed ID: 19667802 DCE-MRI Parameters Have Potential to Predict Response of Locally Advanced Breast Cancer Patients to Neoadjuvant Chemotherapy and Hyperthermia: a Pilot Study International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2009 | Pubmed ID: 19657852 Dynamic Contrast-enhanced Magnetic Resonance Imaging As a Predictor of Clinical Outcome in Canine Spontaneous Soft Tissue Sarcomas Treated with Thermoradiotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2009 | Pubmed ID: 19622579 Antiangiogenic Action of Redox-modulating Mn(III) Meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), Via Suppression of Oxidative Stress in a Mouse Model of Breast Tumor Free Radical Biology & Medicine. Oct, 2009 | Pubmed ID: 19591920 Increased Skin Carcinogenesis in Caspase-activated DNase Knockout Mice Carcinogenesis. Oct, 2009 | Pubmed ID: 19541853 Novel Imaging Provides New Insights into Mechanisms of Oxygen Transport in Tumors Current Molecular Medicine. May, 2009 | Pubmed ID: 19519401 Structural Adaptation and Heterogeneity of Normal and Tumor Microvascular Networks PLoS Computational Biology. May, 2009 | Pubmed ID: 19478883 Analysis of HIF-1 Inhibition by Manassantin A and Analogues with Modified Tetrahydrofuran Configurations Bioorganic & Medicinal Chemistry Letters. Jul, 2009 | Pubmed ID: 19423348 Quantitative Diffuse Reflectance and Fluorescence Spectroscopy: Tool to Monitor Tumor Physiology in Vivo Journal of Biomedical Optics. Mar-Apr, 2009 | Pubmed ID: 19405740 Lipophilicity of Potent Porphyrin-based Antioxidants: Comparison of Ortho and Meta Isomers of Mn(III) N-alkylpyridylporphyrins Free Radical Biology & Medicine. Jul, 2009 | Pubmed ID: 19361553 The Performance of a Reduced-order Adaptive Controller when Used in Multi-antenna Hyperthermia Treatments with Nonlinear Temperature-dependent Perfusion Physics in Medicine and Biology. Apr, 2009 | Pubmed ID: 19265209 Hyperthermia Classic Commentary: 'Arrhenius Relationships from the Molecule and Cell to the Clinic' by William Dewey, Int. J. Hyperthermia, 10:457-483, 1994 International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Feb, 2009 | Pubmed ID: 19219696 Combined Hyperspectral and Spectral Domain Optical Coherence Tomography Microscope for Noninvasive Hemodynamic Imaging Optics Letters. Feb, 2009 | Pubmed ID: 19183634 Nucleophilic Addition of Organozinc Reagents to 2-sulfonyl Cyclic Ethers: Stereoselective Synthesis of Manassantins A and B Organic Letters. Jan, 2009 | Pubmed ID: 19111058 Her2/neu Signaling Blockade Improves Tumor Oxygenation in a Multifactorial Fashion in Her2/neu+ Tumors Cancer Chemotherapy and Pharmacology. Jan, 2009 | Pubmed ID: 18365198 Elevated CAIX Expression is Associated with an Increased Risk of Distant Failure in Early-Stage Cervical Cancer Biomarker Insights. 2008 | Pubmed ID: 19578493 Targeting Lactate-fueled Respiration Selectively Kills Hypoxic Tumor Cells in Mice The Journal of Clinical Investigation. Dec, 2008 | Pubmed ID: 19033663 In Vivo Bioluminescence Imaging Monitoring of Hypoxia-inducible Factor 1alpha, a Promoter That Protects Cells, in Response to Chemotherapy AJR. American Journal of Roentgenology. Dec, 2008 | Pubmed ID: 19020250 Estrogen-related Receptor Alpha is Critical for the Growth of Estrogen Receptor-negative Breast Cancer Cancer Research. Nov, 2008 | Pubmed ID: 18974123 Hyperthermia and Nanotechnology - a Note from the Editor-in-chief International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2008 | Pubmed ID: 18923988 The Pervasive Presence of Fluctuating Oxygenation in Tumors Cancer Research. Jul, 2008 | Pubmed ID: 18632635 Radiofrequency Ablation: the Effect of Distance and Baseline Temperature on Thermal Dose Required for Coagulation International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Nov, 2008 | Pubmed ID: 18608586 Tumor Microvascular Permeability is a Key Determinant for Antivascular Effects of Doxorubicin Encapsulated in a Temperature Sensitive Liposome International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Sep, 2008 | Pubmed ID: 18608573 Low-intensity Alternating Electric Fields: a Potentially Safe and Effective Treatment of Cancer? Onkologie. Jul, 2008 | Pubmed ID: 18596380 Induction of the Human Heat Shock Promoter HSP70B by Nutritional Stress: Implications for Cancer Gene Therapy Cancer Investigation. Jul, 2008 | Pubmed ID: 18584345 Cycling Hypoxia and Free Radicals Regulate Angiogenesis and Radiotherapy Response Nature Reviews. Cancer. Jun, 2008 | Pubmed ID: 18500244 Bromelain Treatment Decreases Neutrophil Migration to Sites of Inflammation Clinical Immunology (Orlando, Fla.). Jul, 2008 | Pubmed ID: 18482869 One-stop-shop Tumor Imaging: Buy Hypoxia, Get Lactate Free The Journal of Clinical Investigation. May, 2008 | Pubmed ID: 18431517 Spectral Imaging Facilitates Visualization and Measurements of Unstable and Abnormal Microvascular Oxygen Transport in Tumors Journal of Biomedical Optics. Jan-Feb, 2008 | Pubmed ID: 18315384 Analytic Solution to Steady-state Radial Diffusion of a Substrate with First-order Reaction Kinetics in the Tissue of a Krogh's Cylinder Radiation Research. Mar, 2008 | Pubmed ID: 18302491 Rationale for and Measurement of Liposomal Drug Delivery with Hyperthermia Using Non-invasive Imaging Techniques International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Feb, 2008 | Pubmed ID: 18214771 PET of Hypoxia and Perfusion with 62Cu-ATSM and 62Cu-PTSM Using a 62Zn/62Cu Generator AJR. American Journal of Roentgenology. Feb, 2008 | Pubmed ID: 18212229 Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated with Bevacizumab and Irinotecan Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2008 | Pubmed ID: 18182667 Inhibition of in Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-specific RNA Aptamer The Journal of Surgical Research. May, 2008 | Pubmed ID: 17950331 RNA Aptamer-targeted Inhibition of NF-kappa B Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2008 | Pubmed ID: 17912235 Radiation and a Metalloporphyrin Radioprotectant in a Mouse Prostate Tumor Model Anticancer Research. Sep-Oct, 2007 | Pubmed ID: 17970050 Low Molecular Weight Catalytic Metalloporphyrin Antioxidant AEOL 10150 Protects Lungs from Fractionated Radiation Free Radical Research. Nov, 2007 | Pubmed ID: 17957541 Predicting Lung Radiotherapy-induced Pneumonitis Using a Model Combining Parametric Lyman Probit with Nonparametric Decision Trees International Journal of Radiation Oncology, Biology, Physics. Jul, 2007 | Pubmed ID: 17637394 Epinephrine-induced Activation of LW-mediated Sickle Cell Adhesion and Vaso-occlusion in Vivo Blood. Oct, 2007 | Pubmed ID: 17609430 Erythropoietin Blockade Inhibits the Induction of Tumor Angiogenesis and Progression PloS One. 2007 | Pubmed ID: 17579721 The Potential Role of Intrinsic Hypoxia Markers As Prognostic Variables in Cancer Antioxidants & Redox Signaling. Aug, 2007 | Pubmed ID: 17571959 Exploring the Role of HIF-1 in Early Angiogenesis and Response to Radiotherapy Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Jun, 2007 | Pubmed ID: 17560674 Requirements for T Lymphocyte Migration in Explanted Lymph Nodes Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17548612 In Memoriam: Edward L Gillette (1932-2006) Radiation Research. Jun, 2007 | Pubmed ID: 17523854 Angiostatin-like Activity of a Monoclonal Antibody to the Catalytic Subunit of F1F0 ATP Synthase Cancer Research. May, 2007 | Pubmed ID: 17510399 Targeting the Molecular Effects of a Hypoxic Tumor Microenvironment Frontiers in Bioscience : a Journal and Virtual Library. 2007 | Pubmed ID: 17485359 Thermal Cycling Enhances the Accumulation of a Temperature-sensitive Biopolymer in Solid Tumors Cancer Research. May, 2007 | Pubmed ID: 17483356 Hypoxia and Radiotherapy: Opportunities for Improved Outcomes in Cancer Treatment Cancer Metastasis Reviews. Jun, 2007 | Pubmed ID: 17440683 Systemic Overexpression of Angiopoietin-2 Promotes Tumor Microvessel Regression and Inhibits Angiogenesis and Tumor Growth Cancer Research. Apr, 2007 | Pubmed ID: 17440098 Regulation of HIF-1alpha Stability Through S-nitrosylation Molecular Cell. Apr, 2007 | Pubmed ID: 17434127 An in Vitro System to Evaluate the Effects of Ischemia on Survival of Cells Used for Cell Therapy Annals of Biomedical Engineering. Aug, 2007 | Pubmed ID: 17417737 Intermittent Hypoxia Furthers the Rationale for Hypoxia-inducible Factor-1 Targeting Cancer Research. Feb, 2007 | Pubmed ID: 17283112 Multiple Etiologies of Tumor Hypoxia Require Multifaceted Solutions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2007 | Pubmed ID: 17255256 A Phase I Trial of Hyperthermia-induced Interleukin-12 Gene Therapy in Spontaneously Arising Feline Soft Tissue Sarcomas Molecular Cancer Therapeutics. Jan, 2007 | Pubmed ID: 17237297 Effects of Fluctuating Oxygenation on Tirapazamine Efficacy: Theoretical Predictions International Journal of Radiation Oncology, Biology, Physics. Feb, 2007 | Pubmed ID: 17236974 Long-term Administration of a Small Molecular Weight Catalytic Metalloporphyrin Antioxidant, AEOL 10150, Protects Lungs from Radiation-induced Injury International Journal of Radiation Oncology, Biology, Physics. Feb, 2007 | Pubmed ID: 17236973 Magnetic Resonance Imaging of Temperature-sensitive Liposome Release: Drug Dose Painting and Antitumor Effects Journal of the National Cancer Institute. Jan, 2007 | Pubmed ID: 17202113 Tumor Necrosis Factor-alpha is a Potent Endogenous Mutagen That Promotes Cellular Transformation Cancer Research. Dec, 2006 | Pubmed ID: 17178846 A Tracer Dose of Technetium-99m-labeled Liposomes Can Estimate the Effect of Hyperthermia on Intratumoral Doxil Extravasation Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2006 | Pubmed ID: 17121901 Anti-angiogenic Effects of Interleukin-12 Delivered by a Novel Hyperthermia Induced Gene Construct International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Nov, 2006 | Pubmed ID: 17079216 Glioma Stem Cells Promote Radioresistance by Preferential Activation of the DNA Damage Response Nature. Dec, 2006 | Pubmed ID: 17051156 Chemodosimetry of in Vivo Tumor Liposomal Drug Concentration Using MRI Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Nov, 2006 | Pubmed ID: 17029236 Extracellular PH and P-31 Magnetic Resonance Spectroscopic Variables Are Related to Outcome in Canine Soft Tissue Sarcomas Treated with Thermoradiotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2006 | Pubmed ID: 17020978 Alternative Inclusion of Fibroblast Growth Factor Receptor 2 Exon IIIc in Dunning Prostate Tumors Reveals Unexpected Epithelial Mesenchymal Plasticity Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16963563 Use of Three-dimensional Tissue Cultures to Model Extravascular Transport and Predict in Vivo Activity of Hypoxia-targeted Anticancer Drugs Journal of the National Cancer Institute. Aug, 2006 | Pubmed ID: 16912264 Assessing the Ability of the Antiangiogenic and Anticytokine Agent Thalidomide to Modulate Radiation-induced Lung Injury International Journal of Radiation Oncology, Biology, Physics. Oct, 2006 | Pubmed ID: 16904841 Phase I Trial of Doxorubicin-containing Low Temperature Sensitive Liposomes in Spontaneous Canine Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2006 | Pubmed ID: 16818699 Intra-peritoneal Cisplatin and Whole Abdomen Hyperthermia for Relapsed Ovarian Carcinoma International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2006 | Pubmed ID: 16754599 Characterization of a Recombinant Adenovirus Vector Encoding Heat-inducible Feline Interleukin-12 for Use in Hyperthermia-induced Gene-therapy International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Mar, 2006 | Pubmed ID: 16754596 Prospective Thermal Dosimetry: the Key to Hyperthermia's Future International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2006 | Pubmed ID: 16754346 Hyperthermia Mediated Liposomal Drug Delivery International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. May, 2006 | Pubmed ID: 16754340 Intertumoral Differences in Hypoxia Selectivity of the PET Imaging Agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2006 | Pubmed ID: 16741309 The G12 Family of Heterotrimeric G Proteins Promotes Breast Cancer Invasion and Metastasis Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16705036 Quantitative Comparison of the Inhibitory Effects of GW5638 and Tamoxifen on Angiogenesis in the Cornea Pocket Assay Angiogenesis. 2006 | Pubmed ID: 16622786 The Effect of Darbepoetin Alfa on Growth, Oxygenation and Radioresponsiveness of a Breast Adenocarcinoma Radiation Research. Feb, 2006 | Pubmed ID: 16518899 Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers Journal of the National Cancer Institute. Mar, 2006 | Pubmed ID: 16507830 Erythropoietin Inhibits Apoptosis in Breast Cancer Cells Via an Akt-dependent Pathway Without Modulating in Vivo Chemosensitivity Molecular Cancer Therapeutics. Feb, 2006 | Pubmed ID: 16505109 Direct Demonstration of Instabilities in Oxygen Concentrations Within the Extravascular Compartment of an Experimental Tumor Cancer Research. Feb, 2006 | Pubmed ID: 16489024 Gene Expression Profiles of Multiple Breast Cancer Phenotypes and Response to Neoadjuvant Chemotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2006 | Pubmed ID: 16467094 A Unique Role of the DNA Fragmentation Factor in Maintaining Genomic Stability Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16432220 Erythropoietin Biology in Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006 | Pubmed ID: 16428469 New PEG-ylated Mn(III) Porphyrins Approaching Catalytic Activity of SOD Enzyme Dalton Transactions (Cambridge, England : 2003). Jan, 2006 | Pubmed ID: 16402149 Optimizing a Novel Regional Chemotherapeutic Agent Against Melanoma: Hyperthermia-induced Enhancement of Temozolomide Cytotoxicity Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006 | Pubmed ID: 16397054 Preferential Extravasation and Accumulation of Liposomal Vincristine in Tumor Comparing to Normal Tissue Enhances Antitumor Activity Cancer Chemotherapy and Pharmacology. Aug, 2006 | Pubmed ID: 16341532 A Comparison of Antiangiogenic Therapies for the Prevention of Liver Metastases The Journal of Surgical Research. Mar, 2006 | Pubmed ID: 16242720 Camptothecin Analogs with Enhanced Activity Against Human Breast Cancer Cells. II. Impact of the Tumor PH Gradient Cancer Chemotherapy and Pharmacology. Jan, 2006 | Pubmed ID: 16001167 Monitoring Metabolite Gradients in the Blood, Liver, and Tumor After Induced Hyperglycemia in Rats with R3230 Flank Tumors Using Microdialysis and Bioluminescence Imaging Advances in Experimental Medicine and Biology. 2005 | Pubmed ID: 16594171 Re-setting the Biologic Rationale for Thermal Therapy International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Dec, 2005 | Pubmed ID: 16338861 Thermal Medicine, Heat Shock Proteins and Cancer International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Dec, 2005 | Pubmed ID: 16338847 Improved Magnetic Resonance Thermal Imaging by Combining Proton Resonance Frequency Shift (PRFS) and Apparent Diffusion Coefficient (ADC) Data International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. Nov, 2005 | Pubmed ID: 16278169 In Regard to Arvold Et Al. (Int J Radiat Oncol Biol Phys 2005;62:207-212) International Journal of Radiation Oncology, Biology, Physics. Nov, 2005 | Pubmed ID: 16199328 Hyperspectral Imaging of Hemoglobin Saturation in Tumor Microvasculature and Tumor Hypoxia Development Journal of Biomedical Optics. Jul-Aug, 2005 | Pubmed ID: 16178638 In Regard to Vasanathan Et Al. (Int J Radiat Oncol Biol Phys 2005;61:145-153) International Journal of Radiation Oncology, Biology, Physics. Oct, 2005 | Pubmed ID: 16168856 A Manganese Porphyrin Superoxide Dismutase Mimetic Enhances Tumor Radioresponsiveness International Journal of Radiation Oncology, Biology, Physics. Oct, 2005 | Pubmed ID: 16168847 Pleiotropic Effects of HIF-1 Blockade on Tumor Radiosensitivity Cancer Cell. Aug, 2005 | Pubmed ID: 16098463 Thermal Dose is Related to Duration of Local Control in Canine Sarcomas Treated with Thermoradiotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2005 | Pubmed ID: 16033838 Method for Improved Accuracy in Endogenous Urea Recovery Marker Calibrations for Microdialysis in Tumors Journal of Pharmacological and Toxicological Methods. Nov-Dec, 2005 | Pubmed ID: 15996879 Observation of Incipient Tumor Angiogenesis That is Independent of Hypoxia and Hypoxia Inducible Factor-1 Activation Cancer Research. Jul, 2005 | Pubmed ID: 15994919 Spatial Heterogeneity and Oxygen Dependence of Glucose Consumption in R3230Ac and Fibrosarcomas of the Fischer 344 Rat Cancer Research. Jun, 2005 | Pubmed ID: 15958560 Overexpression of Extracellular Superoxide Dismutase Reduces Acute Radiation Induced Lung Toxicity BMC Cancer. 2005 | Pubmed ID: 15949035 القياس الآلي من الأوعية الدقيقة سرعة تدفق الدم في الرئة الانبثاث من الجرذان Gert Blueschke*1, Gabi Hanna*2, Andrew N. Fontanella2, Gregory M. Palmer2, Alina Boico2, Hooney Min2, Mark W. Dewhirst2, David C. Irwin3, Yulin Zhao2, Thies Schroeder4 1Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, 2Department of Radiation Oncology, Duke University Medical Center, 3Department of Cardiology, University of Colorado Denver, 4Department of Physical Chemistry, University of Mainz 의학
القياس الآلي من الأوعية الدقيقة سرعة تدفق الدم في الرئة الانبثاث من الجرذان Gert Blueschke*1, Gabi Hanna*2, Andrew N. Fontanella2, Gregory M. Palmer2, Alina Boico2, Hooney Min2, Mark W. Dewhirst2, David C. Irwin3, Yulin Zhao2, Thies Schroeder4 1Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, 2Department of Radiation Oncology, Duke University Medical Center, 3Department of Cardiology, University of Colorado Denver, 4Department of Physical Chemistry, University of Mainz 의학