Michael A. Hill Division of Cardiovascular Medicine University of Missouri Biography Publications Institution JoVE Articles Michael A. Hill has not added a biography. If you are Michael A. Hill and would like to personalize this page please email our Author Liaison for assistance. Publications Sexual Dimorphism in Obesity-Associated Endothelial ENaC Activity and Stiffening in Mice Endocrinology. 12, 2019 | Pubmed ID: 31617909 Epithelial Sodium Channels in Endothelial Cells Mediate Diet-induced Endothelium Stiffness and Impaired Vascular Relaxation in Obese Female Mice Metabolism: Clinical and Experimental. 10, 2019 | Pubmed ID: 31302199 Mineralocorticoid Antagonists and ENaC Inhibitors in Hyperaldosteronism Journal of Clinical Hypertension (Greenwich, Conn.). Jul, 2019 | Pubmed ID: 31169977 TRPV4 Increases Cardiomyocyte Calcium Cycling and Contractility Yet Contributes to Damage in the Aged Heart Following Hypoosmotic Stress Cardiovascular Research. 01, 2019 | Pubmed ID: 29931225 A Calcium Mediated Mechanism Coordinating Vascular Smooth Muscle Cell Adhesion During KCl Activation Frontiers in Physiology. 2018 | Pubmed ID: 30618822 PAI-1 Exacerbates White Adipose Tissue Dysfunction and Metabolic Dysregulation in High Fat Diet-Induced Obesity Frontiers in Pharmacology. 2018 | Pubmed ID: 30319420 Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness Hypertension (Dallas, Tex. : 1979). 09, 2018 | Pubmed ID: 29987104 Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction Hypertension (Dallas, Tex. : 1979). 09, 2018 | Pubmed ID: 29987101 Alpha -adrenergic Stimulation Selectively Enhances Endothelium-mediated Vasodilation in Rat Cremaster Arteries Physiological Reports. 05, 2018 | Pubmed ID: 29756401 Arteriolar Vasodilation Involves Actin Depolymerization American Journal of Physiology. Heart and Circulatory Physiology. 08, 2018 | Pubmed ID: 29727217 Chronic Interval Exercise Training Prevents BK Channel-mediated Coronary Vascular Dysfunction in Aortic-banded Miniswine Journal of Applied Physiology (Bethesda, Md. : 1985). 07, 2018 | Pubmed ID: 29596016 Depletion of Dendritic Cells in Perivascular Adipose Tissue Improves Arterial Relaxation Responses in Type 2 Diabetic Mice Metabolism: Clinical and Experimental. 08, 2018 | Pubmed ID: 29530798 Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity Circulation Research. 02, 2018 | Pubmed ID: 29449364 Enhanced Endothelium Epithelial Sodium Channel Signaling Prompts Left Ventricular Diastolic Dysfunction in Obese Female Mice Metabolism: Clinical and Experimental. 01, 2018 | Pubmed ID: 28920862 Interaction of IL-6 and TNF-α Contributes to Endothelial Dysfunction in Type 2 Diabetic Mouse Hearts PloS One. 2017 | Pubmed ID: 29095915 Angiotensin II Type 1 Receptor Mechanoactivation Involves RGS5 (Regulator of G Protein Signaling 5) in Skeletal Muscle Arteries: Impaired Trafficking of RGS5 in Hypertension Hypertension (Dallas, Tex. : 1979). 12, 2017 | Pubmed ID: 29061726 N-Cadherin, a Novel and Rapidly Remodelling Site Involved in Vasoregulation of Small Cerebral Arteries The Journal of Physiology. 03, 2017 | Pubmed ID: 28008617 Nonenzymatic Glycation Interferes with Fibronectin-integrin Interactions in Vascular Smooth Muscle Cells Microcirculation (New York, N.Y. : 1994). 04, 2017 | Pubmed ID: 28005306 Oxidant Signaling Underlies PKGIα Modulation of Ca2+ Sparks and BKCa in Myogenically Active Arterioles Science Signaling. 10, 2016 | Pubmed ID: 27729549 Vascular Mineralocorticoid Receptor Regulates MicroRNA-155 to Promote Vasoconstriction and Rising Blood Pressure with Aging JCI Insight. Sep, 2016 | Pubmed ID: 27683672 Small Artery Mechanobiology: Roles of Cellular and Non-cellular Elements Microcirculation (New York, N.Y. : 1994). 11, 2016 | Pubmed ID: 27681605 Mechanical Activation of Angiotensin II Type 1 Receptors Causes Actin Remodelling and Myogenic Responsiveness in Skeletal Muscle Arterioles The Journal of Physiology. 12, 2016 | Pubmed ID: 27531064 Arterial Stiffening in Western Diet-Fed Mice Is Associated with Increased Vascular Elastin, Transforming Growth Factor-β, and Plasma Neuraminidase Frontiers in Physiology. 2016 | Pubmed ID: 27458385 Small Artery Elastin Distribution and Architecture-Focus on Three Dimensional Organization Microcirculation (New York, N.Y. : 1994). 11, 2016 | Pubmed ID: 27362628 Inherent Rhythm of Smooth Muscle Cells in Rat Mesenteric Arterioles: An Eigensystem Formulation Physical Review. E. 04, 2016 | Pubmed ID: 27176337 Adiponectin Receptor Agonist, AdipoRon, Causes Vasorelaxation Predominantly Via a Direct Smooth Muscle Action Microcirculation (New York, N.Y. : 1994). Apr, 2016 | Pubmed ID: 26728950 Brief Serotonin Exposure Initiates Arteriolar Inward Remodeling Processes in Vivo That Involve Transglutaminase Activation and Actin Cytoskeleton Reorganization American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2016 | Pubmed ID: 26566730 Regulation of Coronary Endothelial Function by Interactions Between TNF-α, LOX-1 and Adiponectin in Apolipoprotein E Knockout Mice Journal of Vascular Research. 2015 | Pubmed ID: 27050429 Disconnect Between Adipose Tissue Inflammation and Cardiometabolic Dysfunction in Ossabaw Pigs Obesity (Silver Spring, Md.). Dec, 2015 | Pubmed ID: 26524201 Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood Pressure Hypertension (Dallas, Tex. : 1979). Nov, 2015 | Pubmed ID: 26351033 Lymphatic Vascular Integrity is Disrupted in Type 2 Diabetes Due to Impaired Nitric Oxide Signalling Cardiovascular Research. Jul, 2015 | Pubmed ID: 25852084 Inhibition of Myogenic Tone in Rat Cremaster and Cerebral Arteries by SKA-31, an Activator of Endothelial KCa2.3 and KCa3.1 Channels Journal of Cardiovascular Pharmacology. Jul, 2015 | Pubmed ID: 25815673 Heterogeneity in Kv7 Channel Function in the Cerebral and Coronary Circulation Microcirculation (New York, N.Y. : 1994). Feb, 2015 | Pubmed ID: 25476662 Augmented Vascular Smooth Muscle Cell Stiffness and Adhesion when Hypertension is Superimposed on Aging Hypertension (Dallas, Tex. : 1979). Feb, 2015 | Pubmed ID: 25452471 Large Conductance Ca2+-activated K+ Channel (BKCa) α-subunit Splice Variants in Resistance Arteries from Rat Cerebral and Skeletal Muscle Vasculature PloS One. 2014 | Pubmed ID: 24921651 Autoimmune Basis for Postural Tachycardia Syndrome Journal of the American Heart Association. Feb, 2014 | Pubmed ID: 24572257 N-cadherin, a Vascular Smooth Muscle Cell-cell Adhesion Molecule: Function and Signaling for Vasomotor Control Microcirculation (New York, N.Y. : 1994). Apr, 2014 | Pubmed ID: 24521477 Vasoactive Agonists Exert Dynamic and Coordinated Effects on Vascular Smooth Muscle Cell Elasticity, Cytoskeletal Remodelling and Adhesion The Journal of Physiology. Mar, 2014 | Pubmed ID: 24445320 Aldosterone and Vascular Mineralocorticoid Receptors: Regulators of Ion Channels Beyond the Kidney Hypertension (Dallas, Tex. : 1979). Apr, 2014 | Pubmed ID: 24379184 Should We Be Sympathetic to Angiotensin II Infusion? The Journal of Physiology. Nov, 2013 | Pubmed ID: 24187078 Vascular Transcriptional Alterations Produced by Juvenile Obesity in Ossabaw Swine Physiological Genomics. Jun, 2013 | Pubmed ID: 23592636 Mechanisms Underlying Regional Differences in the Ca2+ Sensitivity of BK(Ca) Current in Arteriolar Smooth Muscle The Journal of Physiology. Mar, 2013 | Pubmed ID: 23297302 Does C-reactive Protein Contribute to Atherothrombosis Via Oxidant-mediated Release of Pro-thrombotic Factors and Activation of Platelets? Frontiers in Physiology. 2012 | Pubmed ID: 23162475 수동 압력 직경 관계 및 쥐 Mesenteric Lymphangions의 구조 구성 Lymphatic Research and Biology. Nov, 2012 | Pubmed ID: 23145980 Direct Regulation of Blood Pressure by Smooth Muscle Cell Mineralocorticoid Receptors Nature Medicine. Sep, 2012 | Pubmed ID: 22922412 Arteriolar Vascular Smooth Muscle Cells: Mechanotransducers in a Complex Environment The International Journal of Biochemistry & Cell Biology. Sep, 2012 | Pubmed ID: 22677491 Temporal Analysis of Vascular Smooth Muscle Cell Elasticity and Adhesion Reveals Oscillation Waveforms That Differ with Aging Aging Cell. Oct, 2012 | Pubmed ID: 22639979 Adiponectin Abates Diabetes-induced Endothelial Dysfunction by Suppressing Oxidative Stress, Adhesion Molecules, and Inflammation in Type 2 Diabetic Mice American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012 | Pubmed ID: 22561304 Orthostatic 저 혈압에서 혈관으로 Agonistic 자가: 새로운 메커니즘 Hypertension. Feb, 2012 | Pubmed ID: 22215709 Autoantibody Activation of Beta-adrenergic and Muscarinic Receptors Contributes to an "autoimmune" Orthostatic Hypotension Journal of the American Society of Hypertension : JASH. Jan-Feb, 2012 | Pubmed ID: 22130180 Hydrogen Sulfide Preconditioning or Neutrophil Depletion Attenuates Ischemia-reperfusion-induced Mitochondrial Dysfunction in Rat Small Intestine American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2012 | Pubmed ID: 21921289 Spatial Distribution and Mechanical Function of Elastin in Resistance Arteries: a Role in Bearing Longitudinal Stress Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2011 | Pubmed ID: 21979438 N-cadherin and Integrin Blockade Inhibit Arteriolar Myogenic Reactivity but Not Pressure-induced Increases in Intracellular Ca Frontiers in Physiology. 2010 | Pubmed ID: 21423400 Development of an Image-based System for Measurement of Membrane Potential, Intracellular Ca(2+) and Contraction in Arteriolar Smooth Muscle Cells Microcirculation (New York, N.Y. : 1994). Nov, 2010 | Pubmed ID: 21044217 Antecedent Hydrogen Sulfide Elicits an Anti-inflammatory Phenotype in Postischemic Murine Small Intestine: Role of BK Channels American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2010 | Pubmed ID: 20833953 Large Conductance, Ca2+-activated K+ Channels (BKCa) and Arteriolar Myogenic Signaling FEBS Letters. May, 2010 | Pubmed ID: 20178789 Therapeutic Potential of Pharmacologically Targeting Arteriolar Myogenic Tone Trends in Pharmacological Sciences. Jul, 2009 | Pubmed ID: 19541373 Heterogeneity in Function of Small Artery Smooth Muscle BKCa: Involvement of the Beta1-subunit The Journal of Physiology. Jun, 2009 | Pubmed ID: 19359368 The Plastic Nature of the Vascular Wall: a Continuum of Remodeling Events Contributing to Control of Arteriolar Diameter and Structure Physiology (Bethesda, Md.). Feb, 2009 | Pubmed ID: 19196651 Extracellular Matrix-specific Focal Adhesions in Vascular Smooth Muscle Produce Mechanically Active Adhesion Sites American Journal of Physiology. Cell Physiology. Jul, 2008 | Pubmed ID: 18495809 Decreased Activity of the Smooth Muscle Na+/Ca2+ Exchanger Impairs Arteriolar Myogenic Reactivity The Journal of Physiology. Mar, 2008 | Pubmed ID: 18218677 New Technologies for Dissecting the Arteriolar Myogenic Response Trends in Pharmacological Sciences. Jul, 2007 | Pubmed ID: 17573129 Coupling a Change in Intraluminal Pressure to Vascular Smooth Muscle Depolarization: Still Stretching for an Explanation American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2007 | Pubmed ID: 17384129 복부 대동맥류 마우스 모델에서 맥박 전파 속도, 감도 및 변형률 측정 Neekun Sharma*1,3, Zhe Sun*2,3, Michael A. Hill1,2,3, Chetan P. Hans1,2,3 1Division of Cardiovascular Medicine, University of Missouri, 2Medical Pharmacology and Physiology, University of Missouri, 3Dalton Cardiovascular Research Center, University of Missouri JoVE 60515 면역학 및 감염병학
복부 대동맥류 마우스 모델에서 맥박 전파 속도, 감도 및 변형률 측정 Neekun Sharma*1,3, Zhe Sun*2,3, Michael A. Hill1,2,3, Chetan P. Hans1,2,3 1Division of Cardiovascular Medicine, University of Missouri, 2Medical Pharmacology and Physiology, University of Missouri, 3Dalton Cardiovascular Research Center, University of Missouri JoVE 60515 면역학 및 감염병학