Odete A. B. da Cruz e Silva Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences University of Aveiro Biography Publications Institution JoVE Articles Odete A. B. da Cruz e Silva has not added a biography. If you are Odete A. B. da Cruz e Silva and would like to personalize this page please email our Author Liaison for assistance. Publications Monitoring Clusterin and Fibrillar Structures in Aging and Dementia Aging Brain. 2023 | Pubmed ID: 37346145 Bioinformatic Analysis of the SPs and NFTs Proteomes Unravel Putative Biomarker Candidates for Alzheimer's Disease Proteomics. Apr, 2023 | Pubmed ID: 37062942 Mitochondria Dysfunction and Impaired Response to Oxidative Stress Promotes Proteostasis Disruption in Aged Human Cells Mitochondrion. Mar, 2023 | Pubmed ID: 36273801 Novel Therapeutic Strategies Targeting Mitochondria As a Gateway in Neurodegeneration Neural Regeneration Research. May, 2023 | Pubmed ID: 36254979 Editorial: Digital Health and Neuroscience: Recent History, Current Trends, and Future Developments Frontiers in Integrative Neuroscience. 2022 | Pubmed ID: 36452883 A Bioinformatics Approach Toward Unravelling the Synaptic Molecular Crosstalk Between Alzheimer's Disease and Diabetes Journal of Alzheimer's Disease : JAD. 2022 | Pubmed ID: 35253743 Novel Exosome Biomarker Candidates for Alzheimer's Disease Unravelled Through Mass Spectrometry Analysis Molecular Neurobiology. May, 2022 | Pubmed ID: 35212939 Revisiting APP Secretases: an Overview on the Holistic Effects of Retinoic Acid Receptor Stimulation in APP Processing Cellular and Molecular Life Sciences : CMLS. Jan, 2022 | Pubmed ID: 35089425 Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35008948 The Role of the Integral Type II Transmembrane Protein BRI2 in Health and Disease Cellular and Molecular Life Sciences : CMLS. Nov, 2021 | Pubmed ID: 34480585 Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33920336 Fourier-Transform Infrared Spectroscopy As a Discriminatory Tool for Myotonic Dystrophy Type 1 Metabolism: A Pilot Study International Journal of Environmental Research and Public Health. Apr, 2021 | Pubmed ID: 33917301 The Impact of the Early Phase of the COVID-19 Pandemic on Mental-health Services in Europe The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. Sep, 2021 | Pubmed ID: 33143529 APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis Molecular Neurobiology. Feb, 2021 | Pubmed ID: 33009641 Diagnostic and Therapeutic Potential of Exosomes in Alzheimer's Disease Journal of Neurochemistry. Jan, 2021 | Pubmed ID: 32618370 IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity Current Alzheimer Research. 2020 | Pubmed ID: 33256579 Nuclear Accumulation of LAP1:TRF2 Complex During DNA Damage Response Uncovers a Novel Role for LAP1 Cells. Jul, 2020 | Pubmed ID: 32751253 In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells Cells. Apr, 2020 | Pubmed ID: 32357578 Nuclear Envelope Dysfunction and Its Contribution to the Aging Process Aging Cell. May, 2020 | Pubmed ID: 32291910 Potential of FTIR Spectroscopy Applied to Exosomes for Alzheimer's Disease Discrimination: A Pilot Study Journal of Alzheimer's Disease : JAD. 2020 | Pubmed ID: 32039849 Monitoring Plasma Protein Aggregation During Aging Using Conformation-specific Antibodies and FTIR Spectroscopy Clinica Chimica Acta; International Journal of Clinical Chemistry. Mar, 2020 | Pubmed ID: 31790700 Development of a Library of Thiophene-Based Drug-Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and Cytotoxicity Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2020 | Pubmed ID: 31696989 NMR Metabolomics to Study the Metabolic Response of Human Osteoblasts to Non-poled and Poled Poly (L-lactic) Acid Magnetic Resonance in Chemistry : MRC. Nov, 2019 | Pubmed ID: 31058384 Capacitive Technologies for Highly Controlled and Personalized Electrical Stimulation by Implantable Biomedical Systems Scientific Reports. Mar, 2019 | Pubmed ID: 30899061 Unravelling Protein Aggregation As an Ageing Related Process or a Neuropathological Response Ageing Research Reviews. May, 2019 | Pubmed ID: 30763619 Nuclear Envelope Dynamics During Mammalian Spermatogenesis: New Insights on Male Fertility Biological Reviews of the Cambridge Philosophical Society. Aug, 2019 | Pubmed ID: 30701647 TorsinA Is Functionally Associated with Spermatogenesis Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Feb, 2019 | Pubmed ID: 30246678 Exosome Isolation from Distinct Biofluids Using Precipitation and Column-based Approaches PloS One. 2018 | Pubmed ID: 29889903 Identification and Characterization of the BRI2 Interactome in the Brain Scientific Reports. Feb, 2018 | Pubmed ID: 29476059 ABC Transporters Are Key Players in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29171999 Putative Dementia Cases Fluctuate As a Function of Mini-Mental State Examination Cut-Off Points Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29125486 Toward Neuroproteomics in Biological Psychiatry: A Systems Approach Unravels Okadaic Acid-Induced Alterations in the Neuronal Phosphoproteome Omics : a Journal of Integrative Biology. Sep, 2017 | Pubmed ID: 28934028 Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2017 | Pubmed ID: 28527217 Descriptive Analysis of LAP1 Distribution and That of Associated Proteins Throughout Spermatogenesis Membranes. Apr, 2017 | Pubmed ID: 28387711 Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks Current Alzheimer Research. 2017 | Pubmed ID: 28317487 BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing Journal of Cellular Biochemistry. Sep, 2017 | Pubmed ID: 28176357 Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance Dementia and Geriatric Cognitive Disorders. 2017 | Pubmed ID: 27907913 Altered Protein Phosphorylation As a Resource for Potential AD Biomarkers Scientific Reports. Jul, 2016 | Pubmed ID: 27466139 New Cosurface Capacitive Stimulators for the Development of Active Osseointegrative Implantable Devices Scientific Reports. Jul, 2016 | Pubmed ID: 27456818 Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features Membranes. Jan, 2016 | Pubmed ID: 26784240 Genetic Mutations Strengthen Functional Association of LAP1 with DYT1 Dystonia and Muscular Dystrophy Mutation Research. Reviews in Mutation Research. 2015 | Pubmed ID: 26596547 Amyloid-β Modulates Both AβPP and Tau Phosphorylation Journal of Alzheimer's Disease : JAD. 2015 | Pubmed ID: 25589714 Aβ Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer's Disease Molecular Neurobiology. Dec, 2015 | Pubmed ID: 25344315 LAP1 is a Crucial Protein for the Maintenance of the Nuclear Envelope Structure and Cell Cycle Progression Molecular and Cellular Biochemistry. Jan, 2015 | Pubmed ID: 25323962 RanBP9 Modulates AICD Localization and Transcriptional Activity Via Direct Interaction with Tip60 Journal of Alzheimer's Disease : JAD. 2014 | Pubmed ID: 25024339 Flavonoids As Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer's Disease ACS Chemical Neuroscience. Feb, 2014 | Pubmed ID: 24328060 An Intriguing Shift Occurs in the Novel Protein Phosphatase 1 Binding Partner, TCTEX1D4: Evidence of Positive Selection in a Pika Model PloS One. 2013 | Pubmed ID: 24130861 TCTEX1D4, a Novel Protein Phosphatase 1 Interactor: Connecting the Phosphatase to the Microtubule Network Biology Open. May, 2013 | Pubmed ID: 23789093 Identification and Characterization of Two Distinct PPP1R2 Isoforms in Human Spermatozoa BMC Cell Biology. Mar, 2013 | Pubmed ID: 23506001 Protein Phosphatase 1γ Isoforms Linked Interactions in the Brain Journal of Molecular Neuroscience : MN. May, 2013 | Pubmed ID: 23080069 Attitudes of Portuguese Health Professionals Toward Adverse Drug Reaction Reporting International Journal of Clinical Pharmacy. Oct, 2012 | Pubmed ID: 22936287 Protein Phosphatase 1α Interacting Proteins in the Human Brain Omics : a Journal of Integrative Biology. 2012 | Pubmed ID: 22321011 Identification and Characterization of a Neuronal Enriched Novel Transcript Encoding the Previously Described P60Fe65 Isoform Journal of Neurochemistry. Dec, 2011 | Pubmed ID: 21824145 Identification of the Human Testis Protein Phosphatase 1 Interactome Biochemical Pharmacology. Nov, 2011 | Pubmed ID: 21382349 Protein Phosphatase 1 Complexes Modulate Sperm Motility and Present Novel Targets for Male Infertility Molecular Human Reproduction. Aug, 2011 | Pubmed ID: 21257602 Wnt Signalling is a Relevant Pathway Contributing to Amyloid Beta- Peptide-mediated Neuropathology in Alzheimer's Disease CNS & Neurological Disorders Drug Targets. Dec, 2010 | Pubmed ID: 20942790 Retrieval of the Alzheimer's Amyloid Precursor Protein from the Endosome to the TGN is S655 Phosphorylation State-dependent and Retromer-mediated Molecular Neurodegeneration. Oct, 2010 | Pubmed ID: 20937087 Enhanced Generation of Alzheimer's Amyloid-beta Following Chronic Exposure to Phorbol Ester Correlates with Differential Effects on Alpha and Epsilon Isozymes of Protein Kinase C Journal of Neurochemistry. Jan, 2009 | Pubmed ID: 19012746 Differential Distribution of Alzheimer's Amyloid Precursor Protein Family Variants in Human Sperm Annals of the New York Academy of Sciences. Jan, 2007 | Pubmed ID: 17405931 Altered Subcellular Distribution of the Alzheimer's Amyloid Precursor Protein Under Stress Conditions Annals of the New York Academy of Sciences. Jan, 2007 | Pubmed ID: 17405930 Alternatively Spliced Protein Variants As Potential Therapeutic Targets for Male Infertility and Contraception Annals of the New York Academy of Sciences. Dec, 2004 | Pubmed ID: 15659832 Amyloid Precursor Protein Interaction Network in Human Testis: Sentinel Proteins for Male Reproduction BMC Bioinformatics. | Pubmed ID: 25591988 Author Spotlight: An Optimized Automated Method for Investigating Retinoic Acid Receptors in Neuronal Mitochondria José J. M. Vitória1, Vinícius de Paula1, Odete A. B. da Cruz e Silva1, Diogo Trigo1 1Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro JoVE 65452 신경과학
Author Spotlight: An Optimized Automated Method for Investigating Retinoic Acid Receptors in Neuronal Mitochondria José J. M. Vitória1, Vinícius de Paula1, Odete A. B. da Cruz e Silva1, Diogo Trigo1 1Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro JoVE 65452 신경과학