Paolo Casali Department of Microbiology, Immunology and Molecular Genetics University of Texas Long School of Medicine at San Antonio Biography Publications Institution JoVE Articles Paolo Casali has not added a biography. If you are Paolo Casali and would like to personalize this page please email our Author Liaison for assistance. Publications Activity of Anthracycline- and Ifosfamide-based Chemotherapy in a Series of Patients Affected by Advanced Myxofibrosarcoma Clinical Sarcoma Research. 2017 | Pubmed ID: 28852467 Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma The Oncologist. Jul, 2017 | Pubmed ID: 28754721 Identifying Critical Steps Towards Improved Access to Innovation in Cancer Care: a European CanCer Organisation Position Paper European Journal of Cancer (Oxford, England : 1990). Sep, 2017 | Pubmed ID: 28692951 Radiomic Analysis of Soft Tissues Sarcomas Can Distinguish Intermediate from High-grade Lesions Journal of Magnetic Resonance Imaging : JMRI. Jun, 2017 | Pubmed ID: 28653477 Human Equilibrative Nucleoside Transporter 1 Gene Expression is Associated with Gemcitabine Efficacy in Advanced Leiomyosarcoma and Angiosarcoma British Journal of Cancer. Jul, 2017 | Pubmed ID: 28641307 Histotype-tailored Neoadjuvant Chemotherapy Versus Standard Chemotherapy in Patients with High-risk Soft-tissue Sarcomas (ISG-STS 1001): an International, Open-label, Randomised, Controlled, Phase 3, Multicentre Trial The Lancet. Oncology. Jun, 2017 | Pubmed ID: 28499583 Neoadjuvant Treatment: a Novel Standard? Current Opinion in Oncology. Jul, 2017 | Pubmed ID: 28426465 Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis Cancer Journal (Sudbury, Mass.). Mar/Apr, 2017 | Pubmed ID: 28410293 Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group Annals of Surgery. Apr, 2017 | Pubmed ID: 28394870 Improving Treatment Results with Reference Centres For rare Cancers: Where Do We Stand? European Journal of Cancer (Oxford, England : 1990). May, 2017 | Pubmed ID: 28384534 HSPA8 As a Novel Fusion Partner of NR4A3 in Extraskeletal Myxoid Chondrosarcoma Genes, Chromosomes & Cancer. Jul, 2017 | Pubmed ID: 28383167 Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointestinal Trials Group Intergroup Phase III Randomized Trial on Imatinib at Two Dose Levels Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2017 | Pubmed ID: 28362562 Correction: Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination PloS One. 2017 | Pubmed ID: 28296964 How a Clinical Trial Unit Can Improve Independent Clinical Research in Rare Tumors: the Italian Sarcoma Group Experience Clinical Sarcoma Research. 2017 | Pubmed ID: 28261443 Rad52 Competes with Ku70/Ku86 for Binding to S-region DSB Ends to Modulate Antibody Class-switch DNA Recombination Nature Communications. Feb, 2017 | Pubmed ID: 28176781 Post-relapse Outcomes After Primary Extended Resection of Retroperitoneal Sarcoma: A Report from the Trans-Atlantic RPS Working Group Cancer. Jun, 2017 | Pubmed ID: 28152173 Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST Molecular Cancer Research : MCR. May, 2017 | Pubmed ID: 28130400 ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A Critical Review Critical Reviews in Oncology/hematology. Feb, 2017 | Pubmed ID: 28109409 Advances and Controversies in the Management of Soft Tissue Sarcomas Future Oncology (London, England). Jan, 2017 | Pubmed ID: 27918199 (Neo)adjuvant Treatment in Localised Soft Tissue Sarcoma: The Unsolved Affair European Journal of Cancer (Oxford, England : 1990). Jan, 2017 | Pubmed ID: 27866094 Morcellation Worsens Survival Outcomes in Patients with Undiagnosed Uterine Leiomyosarcomas: A Retrospective MITO Group Study Gynecologic Oncology. Jan, 2017 | Pubmed ID: 27817933 Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment The Journal of Investigative Dermatology. Feb, 2017 | Pubmed ID: 27608549 Biosimilars: a Position Paper of the European Society for Medical Oncology, with Particular Reference to Oncology Prescribers ESMO Open. 2016 | Pubmed ID: 28848668 Career Opportunities and Benefits for Young Oncologists in the European Society for Medical Oncology (ESMO) ESMO Open. 2016 | Pubmed ID: 28255451 ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016 ESMO Open. 2016 | Pubmed ID: 27843641 Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus Journal of Immunology (Baltimore, Md. : 1950). Nov, 2016 | Pubmed ID: 27742832 Epithelioid Peritoneal Mesothelioma: a Hybrid Phenotype Within a Mesenchymal-epithelial/epithelial-mesenchymal Transition Framework Oncotarget. 11, 2016 | Pubmed ID: 27705913 Current Status and Unanswered Questions on the Use of Denosumab in Giant Cell Tumor of Bone Clinical Sarcoma Research. 2016 | Pubmed ID: 27651889 Solitary Fibrous Tumour Presenting with a Single Bone Metastasis: Report of Six Cases and Literature Review Clinical Sarcoma Research. 2016 | Pubmed ID: 27588167 Vascular Resection En-bloc with Tumor Removal and Graft Reconstruction is Safe and Effective in Soft Tissue Sarcoma (STS) of the Extremities and Retroperitoneum Surgical Oncology. Sep, 2016 | Pubmed ID: 27566012 Sirolimus in Advanced Epithelioid Hemangioendothelioma: A Retrospective Case-Series Analysis from the Italian Rare Cancer Network Database Annals of Surgical Oncology. Sep, 2016 | Pubmed ID: 27334221 Systemic Therapy for Selected Skull Base Sarcomas: Chondrosarcoma, Chordoma, Giant Cell Tumour and Solitary Fibrous Tumour/hemangiopericytoma Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. Jul-Aug, 2016 | Pubmed ID: 27330421 Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss Molecular Cancer Research : MCR. Sep, 2016 | Pubmed ID: 27256159 Development and External Validation of Two Nomograms to Predict Overall Survival and Occurrence of Distant Metastases in Adults After Surgical Resection of Localised Soft-tissue Sarcomas of the Extremities: a Retrospective Analysis The Lancet. Oncology. May, 2016 | Pubmed ID: 27068860 Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers Spine. Jun, 2016 | Pubmed ID: 27054448 External Validation of a Multi-institutional Retroperitoneal Sarcoma Nomogram Cancer. May, 2016 | Pubmed ID: 26916507 Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group Annals of Surgery. May, 2016 | Pubmed ID: 26727100 Adjuvant Imatinib for GI Stromal Tumors: When and For How Long? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2016 | Pubmed ID: 26644523 Imatinib Dose Escalation Versus Sunitinib As a Second Line Treatment in KIT Exon 11 Mutated GIST: a Retrospective Analysis Oncotarget. 10, 2016 | Pubmed ID: 26416414 Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP) Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2016 | Pubmed ID: 26261104 Editorial: Epigenetics of B Cells and Antibody Responses Frontiers in Immunology. 2015 | Pubmed ID: 26793194 Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response Frontiers in Immunology. 2015 | Pubmed ID: 26697022 Genome-Wide Analysis Reveals Selective Modulation of MicroRNAs and MRNAs by Histone Deacetylase Inhibitor in B Cells Induced to Undergo Class-Switch DNA Recombination and Plasma Cell Differentiation Frontiers in Immunology. 2015 | Pubmed ID: 26697020 Hormonal Manipulation with Toremifene in Sporadic Desmoid-type Fibromatosis European Journal of Cancer (Oxford, England : 1990). Dec, 2015 | Pubmed ID: 26602014 Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and MicroRNAs: Role in the Antibody Response Frontiers in Immunology. 2015 | Pubmed ID: 26579118 Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomized Trial in Collaboration With the Australasian Gastro-Intestinal Trials Group, UNICANCER, French Sarcoma Group, Italian Sarcoma Group, and Spanish Group for Research on Sarcomas Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2015 | Pubmed ID: 26573069 Feasibility of Preoperative Chemotherapy With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and Superficial Trunk in the Italian Sarcoma Group/Grupo Español De Investigación En Sarcomas Randomized Clinical Trial: Three Versus Five Cycles of Full-Dose Epirubicin Plus Ifosfamide Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2015 | Pubmed ID: 26351345 Imatinib in Advanced Chordoma: A Retrospective Case Series Analysis European Journal of Cancer (Oxford, England : 1990). Nov, 2015 | Pubmed ID: 26283036 Understanding Deviations from Clinical Practice Guidelines in Adult Soft Tissue Sarcoma Studies in Health Technology and Informatics. 2015 | Pubmed ID: 26262055 The GOLD ReGISTry: a Global, Prospective, Observational Registry Collecting Longitudinal Data on Patients with Advanced and Localised Gastrointestinal Stromal Tumours European Journal of Cancer (Oxford, England : 1990). Nov, 2015 | Pubmed ID: 26248685 Hope in Cancer Patients: the Relational Domain As a Crucial Factor Tumori. Jul-Aug, 2015 | Pubmed ID: 26045106 Adjuvant Chemotherapy for Soft Tissue Sarcoma American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Meeting. 2015 | Pubmed ID: 25993233 KIT, PDGFRA, and BRAF Mutational Spectrum Impacts on the Natural History of Imatinib-naive Localized GIST: a Population-based Study The American Journal of Surgical Pathology. Jul, 2015 | Pubmed ID: 25970686 Melan-A/MART-1 Immunity in a EWS-ATF1 Translocated Clear Cell Sarcoma Patient Treated with Sunitinib: a Case Report BMC Cancer. Feb, 2015 | Pubmed ID: 25880253 Development and Validation of Prognostic Nomograms for Metastatic Gastrointestinal Stromal Tumour Treated with Imatinib European Journal of Cancer (Oxford, England : 1990). May, 2015 | Pubmed ID: 25801699 Response of Conventional Chondrosarcoma to Gemcitabine Alone: a Case Report Clinical Sarcoma Research. 2015 | Pubmed ID: 25793102 Trabectedin in Advanced Synovial Sarcomas: a Multicenter Retrospective Study from Four European Institutions and the Italian Rare Cancer Network Anti-cancer Drugs. Jul, 2015 | Pubmed ID: 25763543 B Cell Rab7 Mediates Induction of Activation-induced Cytidine Deaminase Expression and Class-switching in T-dependent and T-independent Antibody Responses Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25740947 Management of Gastrointestinal Stromal Tumour: Current Practices and Visions for the Future Oncology. 2015 | Pubmed ID: 25720422 Myogenic Differentiation and Histologic Grading Are Major Prognostic Determinants in Retroperitoneal Liposarcoma The American Journal of Surgical Pathology. Mar, 2015 | Pubmed ID: 25581729 B Cell TLR1/2, TLR4, TLR7 and TLR9 Interact in Induction of Class Switch DNA Recombination: Modulation by BCR and CD40, and Relevance to T-independent Antibody Responses Autoimmunity. Feb, 2015 | Pubmed ID: 25536171 Sorafenib and Everolimus for Patients with Unresectable High-grade Osteosarcoma Progressing After Standard Treatment: a Non-randomised Phase 2 Clinical Trial The Lancet. Oncology. Jan, 2015 | Pubmed ID: 25498219 Tenosynovial Giant Cell Tumour/pigmented Villonodular Synovitis: Outcome of 294 Patients Before the Era of Kinase Inhibitors European Journal of Cancer (Oxford, England : 1990). Jan, 2015 | Pubmed ID: 25465190 Personalizing the Approach to Retroperitoneal Soft Tissue Sarcoma: Histology-specific Patterns of Failure and Postrelapse Outcome After Primary Extended Resection Annals of Surgical Oncology. May, 2015 | Pubmed ID: 25300609 Folate-related Polymorphisms in Gastrointestinal Stromal Tumours: Susceptibility and Correlation with Tumour Characteristics and Clinical Outcome European Journal of Human Genetics : EJHG. Jun, 2015 | Pubmed ID: 25227144 High-dose Continuous-infusion Ifosfamide in Advanced Well-differentiated/dedifferentiated Liposarcoma Clinical Sarcoma Research. 2014 | Pubmed ID: 25628856 Histone Deacetylase Inhibitors Upregulate B Cell MicroRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses Journal of Immunology (Baltimore, Md. : 1950). Dec, 2014 | Pubmed ID: 25392531 Identification of a Gene Expression Driven Progression Pathway in Myxoid Liposarcoma Oncotarget. Aug, 2014 | Pubmed ID: 25115389 Type II Toxoplasma Gondii Induction of CD40 on Infected Macrophages Enhances Interleukin-12 Responses Infection and Immunity. Oct, 2014 | Pubmed ID: 25024369 Ewing Sarcoma of the Small Bowel: a Study of Seven Cases, Including One with the Uncommonly Reported EWSR1-FEV Translocation Histopathology. Jun, 2014 | Pubmed ID: 24898918 MicroRNAs in Lupus Autoimmunity. Jun, 2014 | Pubmed ID: 24826805 Successes and Limitations of Targeted Cancer Therapy in Gastrointestinal Stromal Tumors Progress in Tumor Research. 2014 | Pubmed ID: 24727986 Emerging Therapies for Adult Soft Tissue Sarcoma Expert Review of Anticancer Therapy. Jun, 2014 | Pubmed ID: 24555529 Desmoid-type Fibromatosis and Pregnancy: a Multi-institutional Analysis of Recurrence and Obstetric Risk Annals of Surgery. May, 2014 | Pubmed ID: 24477160 Policy Statement on Multidisciplinary Cancer Care European Journal of Cancer (Oxford, England : 1990). Feb, 2014 | Pubmed ID: 24321260 Preoperative Chemo-radiation Therapy for Localised Retroperitoneal Sarcoma: a Phase I-II Study from the Italian Sarcoma Group European Journal of Cancer (Oxford, England : 1990). Mar, 2014 | Pubmed ID: 24316063 MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-risk Soft Tissue Sarcoma of Limbs and Trunk Wall: an ISG/GEIS Study Molecular Cancer Therapeutics. Jan, 2014 | Pubmed ID: 24145283 Efficacy and Safety of Trabectedin As an Early Treatment for Advanced or Metastatic Liposarcoma and Leiomyosarcoma Future Oncology (London, England). Jan, 2014 | Pubmed ID: 23987833 Anthracycline-based Chemotherapy in Extraskeletal Myxoid Chondrosarcoma: a Retrospective Study Clinical Sarcoma Research. Dec, 2013 | Pubmed ID: 24345066 Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination PloS One. 2013 | Pubmed ID: 24282540 TSPAN33 is a Novel Marker of Activated and Malignant B Cells Clinical Immunology (Orlando, Fla.). Dec, 2013 | Pubmed ID: 24211713 Combinatorial H3K9acS10ph Histone Modification in IgH Locus S Regions Targets 14-3-3 Adaptors and AID to Specify Antibody Class-switch DNA Recombination Cell Reports. Nov, 2013 | Pubmed ID: 24209747 Targeted Therapies in Rare Sarcomas: IMT, ASPS, SFT, PEComa, and CCS Hematology/oncology Clinics of North America. Oct, 2013 | Pubmed ID: 24093175 Induction of Activation-induced Cytidine Deaminase-targeting Adaptor 14-3-3γ is Mediated by NF-κB-dependent Recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ Promoter and is Sustained by E2A Journal of Immunology (Baltimore, Md. : 1950). Aug, 2013 | Pubmed ID: 23851690 Adjuvant Therapy for High-risk Soft Tissue Sarcoma in the Adult Current Treatment Options in Oncology. Sep, 2013 | Pubmed ID: 23775297 Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors (GIST): the EORTC STBSG Experience Annals of Surgical Oncology. Sep, 2013 | Pubmed ID: 23760587 Localised Thoracic Sarcomas: Outcome Improvement over Time at a Single Institution European Journal of Cancer (Oxford, England : 1990). Aug, 2013 | Pubmed ID: 23683891 Myxoid Liposarcoma and the Mammalian Target of Rapamycin Pathway Current Opinion in Oncology. Jul, 2013 | Pubmed ID: 23673410 Response to Imatinib in Villonodular Pigmented Synovitis (PVNS) Resistant to Nilotinib Clinical Sarcoma Research. May, 2013 | Pubmed ID: 23668619 Epigenetics of the Antibody Response Trends in Immunology. Sep, 2013 | Pubmed ID: 23643790 The Intriguing Patterns of Tumor Response to Trabectedin Expert Review of Anticancer Therapy. Jun, 2013 | Pubmed ID: 23638727 Solitary Fibrous Tumor of All Sites: Outcome of Late Recurrences in 14 Patients Clinical Sarcoma Research. 2013 | Pubmed ID: 23551825 Analyzing the "CareGap": Assessing Gaps in Adherence to Clinical Guidelines in Adult Soft Tissue Sarcoma Studies in Health Technology and Informatics. 2013 | Pubmed ID: 23542965 Improving Methodology to Go Beyond Histology in Rare Cancers The Lancet. Oncology. Apr, 2013 | Pubmed ID: 23477834 Role of Macrophage Targeting in the Antitumor Activity of Trabectedin Cancer Cell. Feb, 2013 | Pubmed ID: 23410977 Regulation of Aicda Expression and AID Activity Autoimmunity. Mar, 2013 | Pubmed ID: 23181381 APRIL Stimulates NF-κB-mediated HoxC4 Induction for AID Expression in Mouse B Cells Cytokine. Feb, 2013 | Pubmed ID: 23178148 Efficacy and Safety of Regorafenib for Advanced Gastrointestinal Stromal Tumours After Failure of Imatinib and Sunitinib (GRID): an International, Multicentre, Randomised, Placebo-controlled, Phase 3 Trial Lancet (London, England). Jan, 2013 | Pubmed ID: 23177515 Polymorphisms in OCTN1 and OCTN2 Transporters Genes Are Associated with Prolonged Time to Progression in Unresectable Gastrointestinal Stromal Tumours Treated with Imatinib Therapy Pharmacological Research. Feb, 2013 | Pubmed ID: 23127916 Rev1 Recruits Ung to Switch Regions and Enhances Du Glycosylation for Immunoglobulin Class Switch DNA Recombination Cell Reports. Nov, 2012 | Pubmed ID: 23140944 Extraskeletal Myxoid Chondrosarcoma: Tumor Response to Sunitinib Clinical Sarcoma Research. Oct, 2012 | Pubmed ID: 23058004 Automatic Detection of Inconsistencies Between Free Text and Coded Data in Sarcoma Discharge Letters Studies in Health Technology and Informatics. 2012 | Pubmed ID: 22874274 Evicase: an Evidence-based Case Structuring Approach for Personalized Healthcare Studies in Health Technology and Informatics. 2012 | Pubmed ID: 22874262 A Retrospective Analysis of Antitumour Activity with Trabectedin in Translocation-related Sarcomas European Journal of Cancer (Oxford, England : 1990). Nov, 2012 | Pubmed ID: 22749255 Adjuvant Therapy of Gastrointestinal Stromal Tumors (GIST) Current Treatment Options in Oncology. Sep, 2012 | Pubmed ID: 22743760 Immunoglobulin Class-switch DNA Recombination: Induction, Targeting and Beyond Nature Reviews. Immunology. Jun, 2012 | Pubmed ID: 22728528 Outcome of Patients with Platelet-derived Growth Factor Receptor Alpha-mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2012 | Pubmed ID: 22718859 Complete Longitudinal Analyses of the Randomized, Placebo-controlled, Phase III Trial of Sunitinib in Patients with Gastrointestinal Stromal Tumor Following Imatinib Failure Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2012 | Pubmed ID: 22661587 B Cell TLRs and Induction of Immunoglobulin Class-switch DNA Recombination Frontiers in Bioscience (Landmark Edition). Jun, 2012 | Pubmed ID: 22652800 Tumor Response Assessment by Modified Choi Criteria in Localized High-risk Soft Tissue Sarcoma Treated with Chemotherapy Cancer. Dec, 2012 | Pubmed ID: 22605504 Pazopanib for Metastatic Soft-tissue Sarcoma (PALETTE): a Randomised, Double-blind, Placebo-controlled Phase 3 Trial Lancet (London, England). May, 2012 | Pubmed ID: 22595799 Iron Inhibits Activation-induced Cytidine Deaminase Enzymatic Activity and Modulates Immunoglobulin Class Switch DNA Recombination The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22556412 Leiomyosarcoma and Sarcoma with Myogenic Differentiation: Two Different Entities or 2 Faces of the Same Disease? Cancer. Nov, 2012 | Pubmed ID: 22517186 BCR-signalling Synergizes with TLR-signalling for Induction of AID and Immunoglobulin Class-switching Through the Non-canonical NF-κB Pathway Nature Communications. Apr, 2012 | Pubmed ID: 22473011 Phase II Study of Imatinib in Advanced Chordoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2012 | Pubmed ID: 22331945 Short, Full-dose Adjuvant Chemotherapy in High-risk Adult Soft Tissue Sarcomas: a Randomized Clinical Trial from the Italian Sarcoma Group and the Spanish Sarcoma Group Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2012 | Pubmed ID: 22312103 Patterns of Care, Prognosis, and Survival in Patients with Metastatic Gastrointestinal Stromal Tumors (GIST) Refractory to First-line Imatinib and Second-line Sunitinib Annals of Surgical Oncology. May, 2012 | Pubmed ID: 22065192 Receptor Tyrosine Kinase Pathway Analysis Sheds Light on Similarities Between Clear-cell Sarcoma and Metastatic Melanoma Genes, Chromosomes & Cancer. Feb, 2012 | Pubmed ID: 22045652 Surgical Technique, Morbidity, and Outcome of Primary Retroperitoneal Sarcoma Involving Inferior Vena Cava Annals of Surgical Oncology. Feb, 2012 | Pubmed ID: 21792507 PML Expression in Soft Tissue Sarcoma: Prognostic and Predictive Value in Alkylating Agents/antracycline-based First Line Therapy Journal of Cellular Physiology. Apr, 2012 | Pubmed ID: 21678421 A New Journal... on Spindle Cells Clinical Sarcoma Research. Jul, 2011 | Pubmed ID: 22613678 Rare Cancers Are Not So Rare: the Rare Cancer Burden in Europe European Journal of Cancer (Oxford, England : 1990). Nov, 2011 | Pubmed ID: 22033323 Natural History of Imatinib-naive GISTs: a Retrospective Analysis of 929 Cases with Long-term Follow-up and Development of a Survival Nomogram Based on Mitotic Index and Size As Continuous Variables The American Journal of Surgical Pathology. Nov, 2011 | Pubmed ID: 21997685 Uterine Sarcomas: a Multidisciplinary Challenge European Journal of Cancer (Oxford, England : 1990). Sep, 2011 | Pubmed ID: 21944001 Trabectedin in Advanced Uterine Leiomyosarcomas: a Retrospective Case Series Analysis from Two Reference Centers Gynecologic Oncology. Dec, 2011 | Pubmed ID: 21917307 AID Dysregulation in Lupus-prone MRL/Fas(lpr/lpr) Mice Increases Class Switch DNA Recombination and Promotes Interchromosomal C-Myc/IgH Loci Translocations: Modulation by HoxC4 Autoimmunity. Dec, 2011 | Pubmed ID: 21585311 Systemic Therapy Options for Unresectable and Metastatic Chordomas Current Oncology Reports. Aug, 2011 | Pubmed ID: 21584646 ERCC5/XPG, ERCC1, and BRCA1 Gene Status and Clinical Benefit of Trabectedin in Patients with Soft Tissue Sarcoma Cancer. Aug, 2011 | Pubmed ID: 21287534 Dermatofibrosarcoma Protuberans-derived Fibrosarcoma: Clinical History, Biological Profile and Sensitivity to Imatinib International Journal of Cancer. Oct, 2011 | Pubmed ID: 21128251 Endonuclease G Plays a Role in Immunoglobulin Class Switch DNA Recombination by Introducing Double-strand Breaks in Switch Regions Molecular Immunology. Jan, 2011 | Pubmed ID: 21111482 A Phase 2 Trial of Imatinib Mesylate in Patients with Recurrent Nonresectable Chondrosarcomas Expressing Platelet-derived Growth Factor Receptor-α or -β: An Italian Sarcoma Group Study Cancer. Feb, 2011 | Pubmed ID: 20925044 Myxofibrosarcoma: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution Annals of Surgical Oncology. Mar, 2011 | Pubmed ID: 20878245 Imatinib Response in Two GIST Patients Carrying Two Hitherto Functionally Uncharacterized PDGFRA Mutations: an Imaging, Biochemical and Molecular Modeling Study International Journal of Cancer. Feb, 2011 | Pubmed ID: 20473908 Fluorescence in Situ Hybridization Analysis and Immunophenotyping of C-Kit/PDGFRA and Bcl-2 Expression in Gastrointestinal Stromal Tumors Analytical and Quantitative Cytology and Histology. Aug, 2010 | Pubmed ID: 21434524 Molecular and Clinicopathologic Characterization of Gastrointestinal Stromal Tumors (GISTs) of Small Size The American Journal of Surgical Pathology. Oct, 2010 | Pubmed ID: 20861712 Estrogen Receptors Bind to and Activate the HOXC4/HoxC4 Promoter to Potentiate HoxC4-mediated Activation-induced Cytosine Deaminase Induction, Immunoglobulin Class Switch DNA Recombination, and Somatic Hypermutation The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20855884 Specific Cross-reaction of Anti-dsDNA Antibody with Platelet Integrin GPIIIa49-66 Autoimmunity. Dec, 2010 | Pubmed ID: 20828249 Novel Models of Myxoid Liposarcoma Xenografts Mimicking the Biological and Pharmacologic Features of Human Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2010 | Pubmed ID: 20732964 14-3-3 Adaptor Proteins Recruit AID to 5'-AGCT-3'-rich Switch Regions for Class Switch Recombination Nature Structural & Molecular Biology. Sep, 2010 | Pubmed ID: 20729863 Alveolar Soft Part Sarcoma: Clinical Presentation, Treatment, and Outcome in a Series of 33 Patients at a Single Institution Annals of Surgical Oncology. Dec, 2010 | Pubmed ID: 20593242 PML Down-regulation in Soft Tissue Sarcomas Journal of Cellular Physiology. Sep, 2010 | Pubmed ID: 20578240 Do Rare Cancers Deserve Specific Strategies for Cancer Research? The Lancet. Oncology. Jun, 2010 | Pubmed ID: 20522374 Trabectedin Therapy for Sarcomas Current Opinion in Oncology. Jul, 2010 | Pubmed ID: 20489618 Sunitinib Malate and Figitumumab in Solitary Fibrous Tumor: Patterns and Molecular Bases of Tumor Response Molecular Cancer Therapeutics. May, 2010 | Pubmed ID: 20457621 Aggressive Surgery in Retroperitoneal Soft Tissue Sarcoma Carried out at High-volume Centers is Safe and is Associated with Improved Local Control Annals of Surgical Oncology. Jun, 2010 | Pubmed ID: 20393803 Toll-like Receptors and B-cell Receptors Synergize to Induce Immunoglobulin Class-switch DNA Recombination: Relevance to Microbial Antibody Responses Critical Reviews in Immunology. 2010 | Pubmed ID: 20370617 Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells Cancer Research. Mar, 2010 | Pubmed ID: 20215499 Histology-specific Nomogram for Primary Retroperitoneal Soft Tissue Sarcoma Cancer. May, 2010 | Pubmed ID: 20209615 Analysis of Receptor Tyrosine Kinases (RTKs) and Downstream Pathways in Chordomas Neuro-oncology. Aug, 2010 | Pubmed ID: 20164240 Extremity Soft Tissue Sarcoma in a Series of Patients Treated at a Single Institution: Local Control Directly Impacts Survival Annals of Surgery. Mar, 2010 | Pubmed ID: 20130465 Chordoma of the Mobile Spine and Sacrum: a Retrospective Analysis of a Series of Patients Surgically Treated at Two Referral Centers Annals of Surgical Oncology. Jan, 2010 | Pubmed ID: 19847568 International Collaborations in Cancer Control and the Third International Cancer Control Congress Tumori. Sep-Oct, 2009 | Pubmed ID: 19999949 A Phase I Study of Single-agent Nilotinib or in Combination with Imatinib in Patients with Imatinib-resistant Gastrointestinal Stromal Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2009 | Pubmed ID: 19723647 Translocation-related Sarcomas Seminars in Oncology. Aug, 2009 | Pubmed ID: 19664492 Absence of Progression As Assessed by Response Evaluation Criteria in Solid Tumors Predicts Survival in Advanced GI Stromal Tumors Treated with Imatinib Mesylate: the Intergroup EORTC-ISG-AGITG Phase III Trial Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2009 | Pubmed ID: 19620483 Desmoid-type Fibromatosis: a Front-line Conservative Approach to Select Patients for Surgical Treatment Annals of Surgical Oncology. Sep, 2009 | Pubmed ID: 19568815 HoxC4 Binds to the Promoter of the Cytidine Deaminase AID Gene to Induce AID Expression, Class-switch DNA Recombination and Somatic Hypermutation Nature Immunology. May, 2009 | Pubmed ID: 19363484 Adjuvant Treatment of GIST with Imatinib: Solid Ground or Still Quicksand? A Comment on Behalf of the EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group, the NCRI Sarcoma Clinical Studies Group (UK), the Japanese Study Group on GIST, the French Sarcoma Group and the Spanish Sarcoma Group (GEIS) European Journal of Cancer (Oxford, England : 1990). May, 2009 | Pubmed ID: 19286368 Resection of Uninvolved Adjacent Organs Can Be Part of Surgery for Retroperitoneal Soft Tissue Sarcoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2009 | Pubmed ID: 19273692 High-grade Soft-tissue Sarcomas: Tumor Response Assessment--pilot Study to Assess the Correlation Between Radiologic and Pathologic Response by Using RECIST and Choi Criteria Radiology. May, 2009 | Pubmed ID: 19261927 Trabectedin (ET-743) Promotes Differentiation in Myxoid Liposarcoma Tumors Molecular Cancer Therapeutics. Feb, 2009 | Pubmed ID: 19190116 Response to Sunitinib Malate in Advanced Alveolar Soft Part Sarcoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2009 | Pubmed ID: 19188185 Lupus-prone MRL/faslpr/lpr Mice Display Increased AID Expression and Extensive DNA Lesions, Comprising Deletions and Insertions, in the Immunoglobulin Locus: Concurrent Upregulation of Somatic Hypermutation and Class Switch DNA Recombination Autoimmunity. Feb, 2009 | Pubmed ID: 19156553 Aggressive Surgical Policies in a Retrospectively Reviewed Single-institution Case Series of Retroperitoneal Soft Tissue Sarcoma Patients Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2009 | Pubmed ID: 19047283 Stem Cell Transplantation in Autoimmune Diseases. Foreword Autoimmunity. Dec, 2008 | Pubmed ID: 19117173 Is Autophagy Rather Than Apoptosis the Regression Driver in Imatinib-treated Gastrointestinal Stromal Tumors? Translational Oncology. Dec, 2008 | Pubmed ID: 19043528 AID- and Ung-dependent Generation of Staggered Double-strand DNA Breaks in Immunoglobulin Class Switch DNA Recombination: a Post-cleavage Role for AID Molecular Immunology. Nov, 2008 | Pubmed ID: 18760480 Nature and Functions of Autoantibodies Nature Clinical Practice. Rheumatology. Sep, 2008 | Pubmed ID: 18756274 The Consensus Statement on the Locoregional Treatment of Abdominal Sarcomatosis Journal of Surgical Oncology. Sep, 2008 | Pubmed ID: 18726899 The Prognostic Impact of Dedifferentiation in Retroperitoneal Liposarcoma: a Series of Surgically Treated Patients at a Single Institution Cancer. Oct, 2008 | Pubmed ID: 18704991 A Role for DRAK2 in the Germinal Center Reaction and the Antibody Response Autoimmunity. Aug, 2008 | Pubmed ID: 18568639 Molecular Mechanisms of Autoimmunity Autoimmunity. Mar, 2008 | Pubmed ID: 18324481 Regulation of Aicda Expression and AID Activity: Relevance to Somatic Hypermutation and Class Switch DNA Recombination Critical Reviews in Immunology. 2007 | Pubmed ID: 18197815 Combined Modalities Approach for Localized Adult Extremity Soft-tissue Sarcoma Expert Review of Anticancer Therapy. Aug, 2007 | Pubmed ID: 18028022 Epithelioid Sarcoma: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution Annals of Surgical Oncology. Dec, 2007 | Pubmed ID: 17909905 NCCN Task Force Report: Management of Patients with Gastrointestinal Stromal Tumor (GIST)--update of the NCCN Clinical Practice Guidelines Journal of the National Comprehensive Cancer Network : JNCCN. Jul, 2007 | Pubmed ID: 17624289 A Novel Tyrosine-kinase Selective Inhibitor, Sunitinib, Induces Transient Hypothyroidism by Blocking Iodine Uptake The Journal of Clinical Endocrinology and Metabolism. Sep, 2007 | Pubmed ID: 17595247 Efficacy of Trabectedin (ecteinascidin-743) in Advanced Pretreated Myxoid Liposarcomas: a Retrospective Study The Lancet. Oncology. Jul, 2007 | Pubmed ID: 17586092 Chordoma Current Opinion in Oncology. Jul, 2007 | Pubmed ID: 17545801 Myxoid/round Cell and Pleomorphic Liposarcomas: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution Cancer. Jun, 2007 | Pubmed ID: 17510918 Postoperative Radiotherapy for Synovial Sarcoma of the Head and Neck During Pregnancy: Clinical and Technical Management and Fetal Dose Estimates Tumori. Jan-Feb, 2007 | Pubmed ID: 17455871 C-Kit/PDGFRA Gene Status Alterations Possibly Related to Primary Imatinib Resistance in Gastrointestinal Stromal Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17438095 Surgery of Residual Disease Following Molecular-targeted Therapy with Imatinib Mesylate in Advanced/metastatic GIST Annals of Surgery. Mar, 2007 | Pubmed ID: 17435538 Crystal Structure of a Human Autoimmune Complex Between IgM Rheumatoid Factor RF61 and IgG1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation Journal of Molecular Biology. May, 2007 | Pubmed ID: 17395205 DNA Replication to Aid Somatic Hypermutation Advances in Experimental Medicine and Biology. 2007 | Pubmed ID: 17338180 Imatinib Does Not Induce Cardiac Left Ventricular Failure in Gastrointestinal Stromal Tumours Patients: Analysis of EORTC-ISG-AGITG Study 62005 European Journal of Cancer (Oxford, England : 1990). Apr, 2007 | Pubmed ID: 17336514 Extremity Soft Tissue Sarcoma: Adding to the Prognostic Meaning of Local Failure Annals of Surgical Oncology. May, 2007 | Pubmed ID: 17260106 Advanced Extremity Soft Tissue Sarcoma: Prognostic Effect of Isolated Limb Perfusion in a Series of 88 Patients Treated at a Single Institution Annals of Surgical Oncology. Feb, 2007 | Pubmed ID: 17122991 Molecular and Biochemical Analyses of Platelet-derived Growth Factor Receptor (PDGFR) B, PDGFRA, and KIT Receptors in Chordomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2006 | Pubmed ID: 17145809 Efficacy and Safety of Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumour After Failure of Imatinib: a Randomised Controlled Trial Lancet (London, England). Oct, 2006 | Pubmed ID: 17046465 Malignant Peripheral Nerve Sheath Tumors: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution Cancer. Sep, 2006 | Pubmed ID: 16881077 Predicting Toxicities for Patients with Advanced Gastrointestinal Stromal Tumours Treated with Imatinib: a Study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Trials Group (EORTC-ISG-AGITG) European Journal of Cancer (Oxford, England : 1990). Sep, 2006 | Pubmed ID: 16876399 DNA Repair in Antibody Somatic Hypermutation Trends in Immunology. Jul, 2006 | Pubmed ID: 16737852 Reduced Tetanus Antibody Titers in Overweight Children Autoimmunity. Mar, 2006 | Pubmed ID: 16698670 KIT Mutations and Dose Selection for Imatinib in Patients with Advanced Gastrointestinal Stromal Tumours European Journal of Cancer (Oxford, England : 1990). May, 2006 | Pubmed ID: 16624552 A Role for the MutL Mismatch Repair Mlh3 Protein in Immunoglobulin Class Switch DNA Recombination and Somatic Hypermutation Journal of Immunology (Baltimore, Md. : 1950). May, 2006 | Pubmed ID: 16622010 Prognostic Analysis of Clinicopathologic Factors in 49 Patients with Diffuse Malignant Peritoneal Mesothelioma Treated with Cytoreductive Surgery and Intraperitoneal Hyperthermic Perfusion Annals of Surgical Oncology. Feb, 2006 | Pubmed ID: 16444562 Biased DA/dT Somatic Hypermutation As Regulated by the Heavy Chain Intronic IEmu Enhancer and 3'Ealpha Enhancers in Human Lymphoblastoid B Cells Molecular Immunology. Apr, 2006 | Pubmed ID: 16412510 Prognostic Effect of Re-excision in Adult Soft Tissue Sarcoma of the Extremity Annals of Surgical Oncology. Jan, 2006 | Pubmed ID: 16372156 Dermatofibrosarcoma Protuberans Treated at a Single Institution: a Surgical Disease with a High Cure Rate Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2005 | Pubmed ID: 16234529 Genoma-largo mediada por análise de inibidor HDAC modulação de microRNAs e mRNAs em B células induzidas a recombinação de DNA de classe-interruptor sofrem e diferenciação de células plasmáticas Helia N. Sanchez1, Tian Shen1,2, Dawn Garcia1,3, Zhao Lai1,3, Paolo Casali1, Hong Zan1 1Department of Microbiology, Immunology and Molecular Genetics, University of Texas Long School of Medicine at San Antonio, 2Xiangya School of Medicine, Cental South University, 3Greehey Children’s Cancer Research Institute, University of Texas Long School of Medicine at San Antonio JoVE 55135 면역학 및 감염병학
Genoma-largo mediada por análise de inibidor HDAC modulação de microRNAs e mRNAs em B células induzidas a recombinação de DNA de classe-interruptor sofrem e diferenciação de células plasmáticas Helia N. Sanchez1, Tian Shen1,2, Dawn Garcia1,3, Zhao Lai1,3, Paolo Casali1, Hong Zan1 1Department of Microbiology, Immunology and Molecular Genetics, University of Texas Long School of Medicine at San Antonio, 2Xiangya School of Medicine, Cental South University, 3Greehey Children’s Cancer Research Institute, University of Texas Long School of Medicine at San Antonio JoVE 55135 면역학 및 감염병학
