Patricia B. Hoyer Department of Physiology University of Arizona Biography Publications Institution JoVE Articles Patricia B. Hoyer has not added a biography. If you are Patricia B. Hoyer and would like to personalize this page please email our Author Liaison for assistance. Publications Involvement of a Volatile Metabolite During Phosphoramide Mustard-induced Ovotoxicity Toxicology and Applied Pharmacology. Mar, 2014 | Pubmed ID: 24642057 Acute 7,12-dimethylbenz[a]anthracene Exposure Causes Differential Concentration-dependent Follicle Depletion and Gene Expression in Neonatal Rat Ovaries Toxicology and Applied Pharmacology. Feb, 2014 | Pubmed ID: 24576726 Xenobiotic Effects in the Ovary: Temporary Versus Permanent Infertility Expert Opinion on Drug Metabolism & Toxicology. Apr, 2014 | Pubmed ID: 24450963 In Vivo Time-serial Multi-modality Optical Imaging in a Mouse Model of Ovarian Tumorigenesis Cancer Biology & Therapy. Jan, 2014 | Pubmed ID: 24145178 7,12-dimethylbenz[a]anthracene-induced Malignancies in a Mouse Model of Menopause Comparative Medicine. Feb, 2013 | Pubmed ID: 23561932 Postnatal Exposure to Chromium Through Mother's Milk Accelerates Follicular Atresia in F1 Offspring Through Increased Oxidative Stress and Depletion of Antioxidant Enzymes Free Radical Biology & Medicine. Mar, 2013 | Pubmed ID: 23470461 Two-photon Excited Fluorescence Imaging of Endogenous Contrast in a Mouse Model of Ovarian Cancer Lasers in Surgery and Medicine. Mar, 2013 | Pubmed ID: 23362124 Glutathione S-transferase Class μ Regulation of Apoptosis Signal-regulating Kinase 1 Protein During VCD-induced Ovotoxicity in Neonatal Rat Ovaries Toxicology and Applied Pharmacology. Feb, 2013 | Pubmed ID: 23274565 Analysis of Second-harmonic-generation Microscopy in a Mouse Model of Ovarian Carcinoma Journal of Biomedical Optics. Jul, 2012 | Pubmed ID: 22894485 Modeling Perimenopause in Sprague-Dawley Rats by Chemical Manipulation of the Transition to Ovarian Failure Comparative Medicine. Jun, 2012 | Pubmed ID: 22776052 4-vinylcyclohexene Diepoxide: a Model Chemical for Ovotoxicity Systems Biology in Reproductive Medicine. Feb, 2012 | Pubmed ID: 22239082 Ovarian Expressed Microsomal Epoxide Hydrolase: Role in Detoxification of 4-vinylcyclohexene Diepoxide and Regulation by Phosphatidylinositol-3 Kinase Signaling Toxicology and Applied Pharmacology. Jan, 2012 | Pubmed ID: 22061827 Xenobiotic Effects on Ovarian Preantral Follicles Biology of Reproduction. Nov, 2011 | Pubmed ID: 21697514 Inhibition of Ovarian KIT Phosphorylation by the Ovotoxicant 4-vinylcyclohexene Diepoxide in Rats Biology of Reproduction. Oct, 2011 | Pubmed ID: 21677306 4-Vinylcyclohexene Diepoxide (VCD) Inhibits Mammary Epithelial Differentiation and Induces Fibroadenoma Formation in Female Sprague Dawley Rats Reproductive Toxicology (Elmsford, N.Y.). Jul, 2011 | Pubmed ID: 21621605 Hexavalent Chromium-induced Apoptosis of Granulosa Cells Involves Selective Sub-cellular Translocation of Bcl-2 Members, ERK1/2 and P53 Toxicology and Applied Pharmacology. Mar, 2011 | Pubmed ID: 21262251 Inhibition of PIK3 Signaling Pathway Members by the Ovotoxicant 4-vinylcyclohexene Diepoxide in Rats Biology of Reproduction. Apr, 2011 | Pubmed ID: 21076081 Midkine, a Heparin-binding Protein, is Increased in the Diabetic Mouse Kidney Postmenopause American Journal of Physiology. Renal Physiology. Jan, 2011 | Pubmed ID: 21048029 Experimental Induction of Reduced Ovarian Reserve in a Nonhuman Primate Model (Macaca Fascicularis) Comparative Medicine. Oct, 2010 | Pubmed ID: 21262124 Simultaneous Optical Coherence Tomography and Laser Induced Fluorescence Imaging in Rat Model of Ovarian Carcinogenesis Cancer Biology & Therapy. Sep, 2010 | Pubmed ID: 21108515 A Longitudinal Study of the Effect of Genistein on Bone in Two Different Murine Models of Diminished Estrogen-producing Capacity Journal of Osteoporosis. 2010 | Pubmed ID: 20948578 Retaining Residual Ovarian Tissue Following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice Journal of Osteoporosis. 2010 | Pubmed ID: 20948577 Distribution and Responsiveness of Rat Anti-Müllerian Hormone During Ovarian Development and VCD-induced Ovotoxicity Toxicology and Applied Pharmacology. Nov, 2010 | Pubmed ID: 20816688 Dual Protective Role for Glutathione S-transferase Class Pi Against VCD-induced Ovotoxicity in the Rat Ovary Toxicology and Applied Pharmacology. Sep, 2010 | Pubmed ID: 20542051 The Effect of Diet and Cardiovascular Risk on Ovarian Aging in Cynomolgus Monkeys (Macaca Fascicularis) Menopause (New York, N.Y.). Jul, 2010 | Pubmed ID: 20458254 7,12-dimethylbenz[a]anthracene Induces Sertoli-leydig-cell Tumors in the Follicle-depleted Ovaries of Mice Treated with 4-vinylcyclohexene Diepoxide Comparative Medicine. Feb, 2010 | Pubmed ID: 20158943 Effect of Phosphatidylinositol-3 Kinase Inhibition on Ovotoxicity Caused by 4-vinylcyclohexene Diepoxide and 7, 12-dimethylbenz[a]anthracene in Neonatal Rat Ovaries Toxicology and Applied Pharmacology. Dec, 2009 | Pubmed ID: 19695275 Current Methods in Investigating the Development of the Female Reproductive System Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19495701 Loss of Ovarian Function in the VCD Mouse-model of Menopause Leads to Insulin Resistance and a Rapid Progression into the Metabolic Syndrome American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2009 | Pubmed ID: 19439618 Effects of 4-vinylcyclohexene Diepoxide on Peripubertal and Adult Sprague-Dawley Rats: Ovarian, Clinical, and Pathologic Outcomes Comparative Medicine. Feb, 2009 | Pubmed ID: 19295054 Serum Antimüllerian Hormone Predicts Ovarian Reserve in a Monkey Model Menopause (New York, N.Y.). May-Jun, 2009 | Pubmed ID: 19188851 Evaluation of Ovotoxicity Induced by 7, 12-dimethylbenz[a]anthracene and Its 3,4-diol Metabolite Utilizing a Rat in Vitro Ovarian Culture System Toxicology and Applied Pharmacology. Feb, 2009 | Pubmed ID: 19027032 Steroidogenic Capacity of Residual Ovarian Tissue in 4-vinylcyclohexene Diepoxide-treated Mice Biology of Reproduction. Feb, 2009 | Pubmed ID: 18829706 Effect of CYP2E1 Gene Deletion in Mice on Expression of Microsomal Epoxide Hydrolase in Response to VCD Exposure Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2008 | Pubmed ID: 18622027 Involvement of the KIT/KITL Signaling Pathway in 4-vinylcyclohexene Diepoxide-induced Ovarian Follicle Loss in Rats Biology of Reproduction. Aug, 2008 | Pubmed ID: 18448842 Expression of Ovarian Microsomal Epoxide Hydrolase and Glutathione S-transferase During Onset of VCD-induced Ovotoxicity in B6C3F(1) Mice Toxicology and Applied Pharmacology. Jul, 2008 | Pubmed ID: 18407309 Comparison of Skeletal Effects of Ovariectomy Versus Chemically Induced Ovarian Failure in Mice Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Aug, 2008 | Pubmed ID: 18348702 Behavioral Consequences of Ovarian Atrophy and Estrogen Replacement in the APPswe Mouse Neurobiology of Aging. Oct, 2008 | Pubmed ID: 17451844 Drinking Water with Uranium Below the U.S. EPA Water Standard Causes Estrogen Receptor-dependent Responses in Female Mice Environmental Health Perspectives. Dec, 2007 | Pubmed ID: 18087588 Effects of Impending Ovarian Failure Induced by 4-vinylcyclohexene Diepoxide on Fertility in C57BL/6 Female Mice Comparative Medicine. Oct, 2007 | Pubmed ID: 17974126 Multidetector Computed Tomographic Morphology of Ovaries in Cynomolgus Macaques (Macaca Fascicularis) Journal of the American Association for Laboratory Animal Science : JAALAS. Sep, 2007 | Pubmed ID: 17877330 Involvement of CYP 2E1 Enzyme in Ovotoxicity Caused by 4-vinylcyclohexene and Its Metabolites Toxicology and Applied Pharmacology. Jun, 2007 | Pubmed ID: 17462685 Hormonal Status Affects the Progression of STZ-induced Diabetes and Diabetic Renal Damage in the VCD Mouse Model of Menopause American Journal of Physiology. Renal Physiology. Jul, 2007 | Pubmed ID: 17389681 Development of an Animal Model for Ovotoxicity Using 4-vinylcyclohexene: a Case Study Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Apr, 2007 | Pubmed ID: 17342769 BAX is Involved in Regulating Follicular Growth, but is Dispensable for Follicle Atresia in Adult Mouse Ovaries Reproduction (Cambridge, England). Jan, 2007 | Pubmed ID: 17244737 Involvement of Microsomal Epoxide Hydrolase Enzyme in Ovotoxicity Caused by 7,12-dimethylbenz[a]anthracene Toxicological Sciences : an Official Journal of the Society of Toxicology. Apr, 2007 | Pubmed ID: 17204581 NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Genistein Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Dec, 2006 | Pubmed ID: 17186522 NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Soy Formula Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Aug, 2006 | Pubmed ID: 16998908 Dual Modality Imaging of a Novel Rat Model of Ovarian Carcinogenesis Journal of Biomedical Optics. Jul-Aug, 2006 | Pubmed ID: 16965151 Destruction of Primordial Ovarian Follicles in Adult Cynomolgus Macaques After Exposure to 4-vinylcyclohexene Diepoxide: a Nonhuman Primate Model of the Menopausal Transition Fertility and Sterility. Oct, 2006 | Pubmed ID: 16952357 Effect of Duration of Dosing on Onset of Ovarian Failure in a Chemical-induced Mouse Model of Perimenopause Menopause (New York, N.Y.). May-Jun, 2006 | Pubmed ID: 16735946 Effect of Bcl-2 Overexpression in Mice on Ovotoxicity Caused by 4-vinylcyclohexene Toxicology and Applied Pharmacology. Aug, 2006 | Pubmed ID: 16631218 Characterization of Cyclicity and Hormonal Profile with Impending Ovarian Failure in a Novel Chemical-induced Mouse Model of Perimenopause Comparative Medicine. Dec, 2005 | Pubmed ID: 16422148 Atherosclerotic Lesion Development in a Novel Ovary-intact Mouse Model of Perimenopause Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2005 | Pubmed ID: 15994440 Damage to Ovarian Development and Function Cell and Tissue Research. Oct, 2005 | Pubmed ID: 15856308 Differences Between Rats and Mice in the Involvement of the Aryl Hydrocarbon Receptor in 4-vinylcyclohexene Diepoxide-induced Ovarian Follicle Loss Toxicology and Applied Pharmacology. Mar, 2005 | Pubmed ID: 15710172 Initiation of Delayed Ovotoxicity by in Vitro and in Vivo Exposures of Rat Ovaries to 4-vinylcyclohexene Diepoxide Reproductive Toxicology (Elmsford, N.Y.). Nov, 2004 | Pubmed ID: 15336714 Can the Clock Be Turned Back on Ovarian Aging? Science of Aging Knowledge Environment : SAGE KE. Mar, 2004 | Pubmed ID: 15014203 The Follicle-deplete Mouse Ovary Produces Androgen Biology of Reproduction. Jul, 2004 | Pubmed ID: 14998904 Expression and Activity of Cytochromes P450 2E1, 2A, and 2B in the Mouse Ovary: the Effect of 4-vinylcyclohexene and Its Diepoxide Metabolite Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2003 | Pubmed ID: 12700394 Characterization of a Rat in Vitro Ovarian Culture System to Study the Ovarian Toxicant 4-vinylcyclohexene Diepoxide Toxicology and Applied Pharmacology. Oct, 2002 | Pubmed ID: 12408955 Long-term Effects of Ovarian Follicular Depletion in Rats by 4-vinylcyclohexene Diepoxide Reproductive Toxicology (Elmsford, N.Y.). Nov-Dec, 2002 | Pubmed ID: 12401505 Activation of Mitogen-activated Protein Kinases and AP-1 Transcription Factor in Ovotoxicity Induced by 4-vinylcyclohexene Diepoxide in Rats Biology of Reproduction. Sep, 2002 | Pubmed ID: 12193377 In Vitro Ovarian Tissue and Organ Culture: a Review Frontiers in Bioscience : a Journal and Virtual Library. Sep, 2002 | Pubmed ID: 12161346 Expression and Activity of Microsomal Epoxide Hydrolase in Follicles Isolated from Mouse Ovaries Toxicological Sciences : an Official Journal of the Society of Toxicology. Jul, 2002 | Pubmed ID: 12075107 Mdr1a Deficiency Corrects Sterility in Niemann-Pick C1 Protein Deficient Female Mice Molecular Reproduction and Development. Jun, 2002 | Pubmed ID: 11984826 17beta-estradiol Affords Protection Against 4-vinylcyclohexene Diepoxide-induced Ovarian Follicle Loss in Fischer-344 Rats Endocrinology. Mar, 2002 | Pubmed ID: 11861533 A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice Hao Chen1, Jessica N. Perez1, Eleni Constantopoulos1, Laurel McKee1, Jessica Regan1, Patricia B. Hoyer1, Heddwen L. Brooks1, John Konhilas1 1Department of Physiology, University of Arizona JoVE 51083 의학
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice Hao Chen1, Jessica N. Perez1, Eleni Constantopoulos1, Laurel McKee1, Jessica Regan1, Patricia B. Hoyer1, Heddwen L. Brooks1, John Konhilas1 1Department of Physiology, University of Arizona JoVE 51083 의학