Peter ten Dijke Dept. Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Peter ten Dijke has not added a biography. If you are Peter ten Dijke and would like to personalize this page please email our Author Liaison for assistance. Publications A Comprehensive Enhancer Screen Identifies TRAM2 As a Key and Novel Mediator of YAP Oncogenesis Genome Biology. Jan, 2021 | Pubmed ID: 33514403 E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33418880 Targeting TGFβ Signal Transduction for Cancer Therapy Signal Transduction and Targeted Therapy. Jan, 2021 | Pubmed ID: 33414388 Therapeutic Targeting of TGF-β in Cancer: Hacking a Master Switch of Immune Suppression Clinical Science (London, England : 1979). Jan, 2021 | Pubmed ID: 33399850 Uncovering the Deubiquitinase Activity Landscape of Breast Cancer Oncoscience. Nov, 2020 | Pubmed ID: 33457450 TGF-β Signaling in Liver Metastasis Clinical and Translational Medicine. Nov, 2020 | Pubmed ID: 33252863 Designed Nanomolar Small-molecule Inhibitors of Ena/VASP EVH1 Interaction Impair Invasion and Extravasation of Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33184177 Current Perspectives on Inhibitory SMAD7 in Health and Disease Critical Reviews in Biochemistry and Molecular Biology. Oct, 2020 | Pubmed ID: 33081543 Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos Journal of the American Chemical Society. Sep, 2020 | Pubmed ID: 32886496 Mechanotransduction is a Context-dependent Activator of TGF-β Signaling in Mesenchymal Stem Cells Biomaterials. Nov, 2020 | Pubmed ID: 32836056 Cercosporamide Inhibits Bone Morphogenetic Protein Receptor Type I Kinase Activity in Zebrafish Disease Models & Mechanisms. Sep, 2020 | Pubmed ID: 32820031 Reactivation of BMP Signaling by Suboptimal Concentrations of MEK Inhibitor and FK506 Reduces Organ-specific Breast Cancer Metastasis Cancer Letters. Nov, 2020 | Pubmed ID: 32768522 On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges? Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32733895 Role of Glycosylation in TGF-β Signaling and Epithelial-to-mesenchymal Transition in Cancer Protein & Cell. Jun, 2020 | Pubmed ID: 32583064 Differential - and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior Frontiers in Oncology. 2020 | Pubmed ID: 32582529 MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension International Journal of Molecular Sciences. Jun, 2020 | Pubmed ID: 32531895 Bone Morphogenetic Protein Receptors: Structure, Function and Targeting by Selective Small Molecule Kinase Inhibitors Bone. Sep, 2020 | Pubmed ID: 32522605 Secreted BMP Antagonists and Their Role in Cancer and Bone Metastases Bone. Aug, 2020 | Pubmed ID: 32473315 TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32373613 TGFβ and EGF Signaling Orchestrates the AP-1- and P63 Transcriptional Regulation of Breast Cancer Invasiveness Oncogene. May, 2020 | Pubmed ID: 32350443 Development of a 96-well Plate Sample Preparation Method for Integrated N- and O-glycomics Using Porous Graphitized Carbon Liquid Chromatography-mass Spectrometry Molecular Omics. 08, 2020 | Pubmed ID: 32281997 Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses Trends in Immunology. 05, 2020 | Pubmed ID: 32223932 A Signaling Crosstalk Between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival Cells. 03, 2020 | Pubmed ID: 32204446 Controlling Smad4 Signaling with a Wip EMBO Reports. 05, 2020 | Pubmed ID: 32189449 Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas Cancer Cell. 03, 2020 | Pubmed ID: 32142668 THG-1 Suppresses SALL4 Degradation to Induce Stemness Genes and Tumorsphere Formation Through Antagonizing NRBP1 in Squamous Cell Carcinoma Cells Biochemical and Biophysical Research Communications. 03, 2020 | Pubmed ID: 31864704 TGFβ-induced Metabolic Reprogramming During Epithelial-to-mesenchymal Transition in Cancer Cellular and Molecular Life Sciences : CMLS. Jun, 2020 | Pubmed ID: 31822964 Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure Diabetes. 02, 2020 | Pubmed ID: 31732500 VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells JBMR Plus. Nov, 2019 | Pubmed ID: 31768489 JNK-Dependent CJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses Cells. 11, 2019 | Pubmed ID: 31766464 A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment Biomolecules. 11, 2019 | Pubmed ID: 31744193 Author Correction: C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. Nov, 2019 | Pubmed ID: 31704935 GREM1 is Associated with Metastasis and Predicts Poor Prognosis in ER-negative Breast Cancer Patients Cell Communication and Signaling : CCS. 11, 2019 | Pubmed ID: 31694641 C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. 09, 2019 | Pubmed ID: 31554791 Cancer-associated Fibroblast-derived Gremlin 1 Promotes Breast Cancer Progression Breast Cancer Research : BCR. 09, 2019 | Pubmed ID: 31533776 In Vivo Imaging of TGFβ Signalling Components Using Positron Emission Tomography Drug Discovery Today. 12, 2019 | Pubmed ID: 31494189 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Prevention of Progression of Pulmonary Hypertension by the Nur77 Agonist 6-mercaptopurine: Role of BMP Signalling The European Respiratory Journal. 09, 2019 | Pubmed ID: 31273046 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 Generation of Non-standard Macrocyclic Peptides Specifically Binding TSC-22 Homologous Gene-1 Biochemical and Biophysical Research Communications. 08, 2019 | Pubmed ID: 31227214 TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis International Journal of Molecular Sciences. Jun, 2019 | Pubmed ID: 31195692 Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer Cancers. May, 2019 | Pubmed ID: 31137748 Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models Cells. 04, 2019 | Pubmed ID: 30959852 TGF-β Family Signaling Pathways in Cellular Dormancy Trends in Cancer. 01, 2019 | Pubmed ID: 30616757 Inflammation Induces Endothelial-to-mesenchymal Transition and Promotes Vascular Calcification Through Downregulation of BMPR2 The Journal of Pathology. 03, 2019 | Pubmed ID: 30430573 Bone Morphogenetic Protein Receptor Signal Transduction in Human Disease The Journal of Pathology. 01, 2019 | Pubmed ID: 30246251 The Therapeutic Potential of Targeting the Endothelial-to-mesenchymal Transition Angiogenesis. 02, 2019 | Pubmed ID: 30076548 Epithelial-mesenchymal-transition-inducing Transcription Factors: New Targets for Tackling Chemoresistance in Cancer? Oncogene. 11, 2018 | Pubmed ID: 30002444 Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 12, 2018 | Pubmed ID: 29945992 Bone Morphogenetic Protein 9 As a Key Regulator of Liver Progenitor Cells in DDC-induced Cholestatic Liver Injury Liver International : Official Journal of the International Association for the Study of the Liver. 09, 2018 | Pubmed ID: 29751359 TGF-β Family Co-receptor Function and Signaling Acta Biochimica Et Biophysica Sinica. Jan, 2018 | Pubmed ID: 29293886 JUNB Governs a Feed-forward Network of TGFβ Signaling That Aggravates Breast Cancer Invasion Nucleic Acids Research. 02, 2018 | Pubmed ID: 29186616 Endothelial-to-mesenchymal Transition in Cardiovascular Diseases: Developmental Signaling Pathways Gone Awry Developmental Dynamics : an Official Publication of the American Association of Anatomists. 03, 2018 | Pubmed ID: 28891150 Breast Cancer Metastasis Suppressor OTUD1 Deubiquitinates SMAD7 Nature Communications. 12, 2017 | Pubmed ID: 29235476 TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases International Journal of Molecular Sciences. Oct, 2017 | Pubmed ID: 29039786 Disparate Phospho-Smad2 Levels in Advanced Type 2 Diabetes Patients with Diabetic Nephropathy and Early Experimental Db/db Mouse Model Renal Failure. Nov, 2017 | Pubmed ID: 28805484 Bone Morphogenetic Protein 9 Protects Against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation Frontiers in Physiology. 2017 | Pubmed ID: 28751863 Targeting TGF-β Signaling in Cancer Trends in Cancer. 01, 2017 | Pubmed ID: 28718426 SUMO-triggered Ubiquitination of NR4A1 Controls Macrophage Cell Death Cell Death and Differentiation. 09, 2017 | Pubmed ID: 28622293 TGFβ1-induced SMAD2/3 and SMAD1/5 Phosphorylation Are Both ALK5-kinase-dependent in Primary Chondrocytes and Mediated by TAK1 Kinase Activity Arthritis Research & Therapy. May, 2017 | Pubmed ID: 28569204 Erratum To: BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28536788 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28447104 FAF1 Phosphorylation by AKT Accumulates TGF-β Type II Receptor and Drives Breast Cancer Metastasis Nature Communications. 04, 2017 | Pubmed ID: 28443643 Bone Morphogenetic Proteins in Vascular Homeostasis and Disease Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348038 TGF-β Signaling in Control of Cardiovascular Function Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348036 BMP-9 Interferes with Liver Regeneration and Promotes Liver Fibrosis Gut. May, 2017 | Pubmed ID: 28336518 Fluid Shear Stress-induced TGF-β/ALK5 Signaling in Renal Epithelial Cells is Modulated by MEK1/2 Cellular and Molecular Life Sciences : CMLS. Feb, 2017 | Pubmed ID: 28168444 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-β Family Members Nephron. 2017 | Pubmed ID: 28064277 New Function of the Myostatin/activin Type I Receptor (ALK4) As a Mediator of Muscle Atrophy and Muscle Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2017 | Pubmed ID: 27733450 Fish Tales: The Use of Zebrafish Xenograft Human Cancer Cell Models Histology and Histopathology. Dec, 2016 | Pubmed ID: 27933602 Immunoregulation by Members of the TGFβ Superfamily Nature Reviews. Immunology. 11, 2016 | Pubmed ID: 27885276 Towards a Cure for Fibrodysplasia Ossificans Progressiva Annals of Translational Medicine. Oct, 2016 | Pubmed ID: 27867996 Mutational Activation of BRAF Confers Sensitivity to Transforming Growth Factor Beta Inhibitors in Human Cancer Cells Oncotarget. Dec, 2016 | Pubmed ID: 27835901 Targeting Tumour Vasculature by Inhibiting Activin Receptor-like Kinase (ALK)1 Function Biochemical Society Transactions. Aug, 2016 | Pubmed ID: 27528762 A Current Perspective on Applications of Macrocyclic-peptide-based High-affinity Ligands Biopolymers. Nov, 2016 | Pubmed ID: 27352774 C-Myb Enhances Breast Cancer Invasion and Metastasis Through the Wnt/β-Catenin/Axin2 Pathway Cancer Research. Jun, 2016 | Pubmed ID: 27197202 Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression The American Journal of Pathology. Jul, 2016 | Pubmed ID: 27171900 Regulation of the TGF-β Pathway by Deubiquitinases in Cancer The International Journal of Biochemistry & Cell Biology. Jul, 2016 | Pubmed ID: 27155333 Smad6 Determines BMP-regulated Invasive Behaviour of Breast Cancer Cells in a Zebrafish Xenograft Model Scientific Reports. Apr, 2016 | Pubmed ID: 27113436 Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease Journal of the American Society of Nephrology : JASN. Dec, 2016 | Pubmed ID: 27020852 Emerging Regulators of BMP Bioavailability Bone. Dec, 2016 | Pubmed ID: 26825814 The Rationale for Targeting TGF-β in Chronic Liver Diseases European Journal of Clinical Investigation. Apr, 2016 | Pubmed ID: 26823073 TGF-β Signalling and Liver Disease The FEBS Journal. Jun, 2016 | Pubmed ID: 26807763 Interrogating TGF-β Function and Regulation in Endothelial Cells Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520125 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 In Brief: Endothelial-to-mesenchymal Transition The Journal of Pathology. Feb, 2016 | Pubmed ID: 26446982 Regulatory RNAs Controlling Vascular (dys)function by Affecting TGF-ß Family Signalling EXCLI Journal. 2015 | Pubmed ID: 26862319 Signal Transduction: Gain of Activin Turns Muscle into Bone Current Biology : CB. Dec, 2015 | Pubmed ID: 26654374 Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva Stem Cell Reports. Dec, 2015 | Pubmed ID: 26626181 Targeting BMP Signalling in Cardiovascular Disease and Anaemia Nature Reviews. Cardiology. Oct, 2015 | Pubmed ID: 26461965 Bone Morphogenetic Protein 6 and Oxidized Low-density Lipoprotein Synergistically Recruit Osteogenic Differentiation in Endothelial Cells Cardiovascular Research. Nov, 2015 | Pubmed ID: 26410368 Heterozygous Disruption of Activin Receptor-like Kinase 1 is Associated with Increased Arterial Pressure in Mice Disease Models & Mechanisms. Nov, 2015 | Pubmed ID: 26398936 Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2015 | Pubmed ID: 26373572 Bone Morphogenetic Protein Signaling in Bone Homeostasis Bone. Nov, 2015 | Pubmed ID: 26051467 A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins Journal of Virology. Aug, 2015 | Pubmed ID: 26041291 Genetic Depletion and Pharmacological Targeting of αv Integrin in Breast Cancer Cells Impairs Metastasis in Zebrafish and Mouse Xenograft Models Breast Cancer Research : BCR. Feb, 2015 | Pubmed ID: 25849225 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 14-3-3ζ Turns TGF-β to the Dark Side Cancer Cell. Feb, 2015 | Pubmed ID: 25670073 SLUG is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2015 | Pubmed ID: 25633317 Clinical Utility Gene Card For: Fibrodysplasia Ossificans Progressiva European Journal of Human Genetics : EJHG. Oct, 2015 | Pubmed ID: 25604857 Inhibition of TGFβ Type I Receptor Activity Facilitates Liver Regeneration Upon Acute CCl4 Intoxication in Mice Archives of Toxicology. Jan, 2015 | Pubmed ID: 25566828 Ter94/VCP is a Novel Component Involved in BMP Signaling PloS One. 2014 | Pubmed ID: 25469707 Wild-type P53 Inhibits Pro-invasive Properties of TGF-β3 in Breast Cancer, in Part Through Regulation of EPHB2, a New TGF-β Target Gene Breast Cancer Research and Treatment. Nov, 2014 | Pubmed ID: 25257729 Assessment of Functional Competence of Endothelial Cells from Human Pluripotent Stem Cells in Zebrafish Embryos Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25173378 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 Generation, Expansion and Functional Analysis of Endothelial Cells and Pericytes Derived from Human Pluripotent Stem Cells Nature Protocols. 2014 | Pubmed ID: 24874816 Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis Via Activation of Rho and ROCK Gastroenterology. Jul, 2014 | Pubmed ID: 24704720 Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor Molecular Therapy. Nucleic Acids. Apr, 2014 | Pubmed ID: 24691207 Nuclear Receptor NR4A1 Promotes Breast Cancer Invasion and Metastasis by Activating TGF-β Signalling Nature Communications. 2014 | Pubmed ID: 24584437 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides Molecular Therapy. Nucleic Acids. 2014 | Pubmed ID: 24448195 Functionality of Endothelial Cells and Pericytes from Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158517 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Signaling Interplay Between Transforming Growth Factor-β Receptor and PI3K/AKT Pathways in Cancer Trends in Biochemical Sciences. Dec, 2013 | Pubmed ID: 24239264 Transforming Growth Factor-β Signalling Controls Human Breast Cancer Metastasis in a Zebrafish Xenograft Model Breast Cancer Research : BCR. Nov, 2013 | Pubmed ID: 24196484 Activin Receptor-like Kinase 1 As a Target for Anti-angiogenesis Therapy Expert Opinion on Investigational Drugs. Nov, 2013 | Pubmed ID: 24053899 Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation The Journal of Biological Chemistry. Oct, 2013 | Pubmed ID: 24005672 TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis Molecular Cell. Sep, 2013 | Pubmed ID: 23973329 FK506 Activates BMPR2, Rescues Endothelial Dysfunction, and Reverses Pulmonary Hypertension The Journal of Clinical Investigation. Aug, 2013 | Pubmed ID: 23867624 Antisense-oligonucleotide Mediated Exon Skipping in Activin-receptor-like Kinase 2: Inhibiting the Receptor That is Overactive in Fibrodysplasia Ossificans Progressiva PloS One. 2013 | Pubmed ID: 23861958 Three-dimensional Co-cultures of Human Endothelial Cells and Embryonic Stem Cell-derived Pericytes Inside a Microfluidic Device Lab on a Chip. Sep, 2013 | Pubmed ID: 23702711 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 Snail and Slug, Key Regulators of TGF-β-induced EMT, Are Sufficient for the Induction of Single-cell Invasion Biochemical and Biophysical Research Communications. May, 2013 | Pubmed ID: 23618854 Preventive and Therapeutic Effects of Smad7 on Radiation-induced Oral Mucositis Nature Medicine. Apr, 2013 | Pubmed ID: 23475202 Fine-tuning BMP7 Signalling in Adipogenesis by UBE2O/E2-230K-mediated Monoubiquitination of SMAD6 The EMBO Journal. Apr, 2013 | Pubmed ID: 23455153 Deficiency for Endoglin in Tumor Vasculature Weakens the Endothelial Barrier to Metastatic Dissemination The Journal of Experimental Medicine. Mar, 2013 | Pubmed ID: 23401487 UBE2O Negatively Regulates TRAF6-mediated NF-κB Activation by Inhibiting TRAF6 Polyubiquitination Cell Research. Mar, 2013 | Pubmed ID: 23381138 Endoglin for Tumor Imaging and Targeted Cancer Therapy Expert Opinion on Therapeutic Targets. Apr, 2013 | Pubmed ID: 23327677 Overactive Bone Morphogenetic Protein Signaling in Heterotopic Ossification and Duchenne Muscular Dystrophy Cellular and Molecular Life Sciences : CMLS. Feb, 2013 | Pubmed ID: 22752156 Soluble Fms-like Tyrosine Kinase 1 and Soluble Endoglin Are Elevated Circulating Anti-angiogenic Factors in Pre-eclampsia Pregnancy Hypertension. Oct, 2012 | Pubmed ID: 26105603 MicroRNA-155 Functions As a Negative Regulator of RhoA Signaling in TGF-β-induced Endothelial to Mesenchymal Transition MicroRNA (Shariqah, United Arab Emirates). 2012 | Pubmed ID: 25048084 慢性肝疾患の動物モデル。 American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2012 | Pubmed ID: 23275613 MED12 Controls the Response to Multiple Cancer Drugs Through Regulation of TGF-β Receptor Signaling Cell. Nov, 2012 | Pubmed ID: 23178117 The Activities of Smad and Gli Mediated Signalling Pathways in High-grade Conventional Osteosarcoma European Journal of Cancer (Oxford, England : 1990). Dec, 2012 | Pubmed ID: 22868198 Fas-associated Factor 1 is a Scaffold Protein That Promotes β-transducin Repeat-containing Protein (β-TrCP)-mediated β-catenin Ubiquitination and Degradation The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22730322 TGF-β Signalling and Its Role in Cancer Progression and Metastasis Cancer Metastasis Reviews. Dec, 2012 | Pubmed ID: 22714591 BMP Signaling in Vascular Diseases FEBS Letters. Jul, 2012 | Pubmed ID: 22710160 USP4 is Regulated by AKT Phosphorylation and Directly Deubiquitylates TGF-β Type I Receptor Nature Cell Biology. Jun, 2012 | Pubmed ID: 22706160 TGFβ Signaling in Liver Regeneration Current Pharmaceutical Design. 2012 | Pubmed ID: 22630085 Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva Current Pharmaceutical Design. 2012 | Pubmed ID: 22630080 Role of Endoglin in Fibrosis and Scleroderma International Review of Cell and Molecular Biology. 2012 | Pubmed ID: 22608563 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation Molecular Cell. Jun, 2012 | Pubmed ID: 22560923 Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22493445 Shear Induced Collateral Artery Growth Modulated by Endoglin but Not by ALK1 Journal of Cellular and Molecular Medicine. Oct, 2012 | Pubmed ID: 22436015 Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer Cancer Research. Apr, 2012 | Pubmed ID: 22396497 TGF-β Signaling in Endothelial-to-mesenchymal Transition: the Role of Shear Stress and Primary Cilia Science Signaling. Feb, 2012 | Pubmed ID: 22355187 ユビキチン蛋白質修飾 TGFβ シグナル伝達に重要な役割。 Upsala Journal of Medical Sciences. Feb, 2012 | Pubmed ID: 22335355 Wnt/β-カテニン シグナル伝達 C2C12 筋芽細胞の増殖と分化を Id3 式を誘導することによって変更します。 Biochemical and Biophysical Research Communications. Feb, 2012 | Pubmed ID: 22326917 乳腺の開発と癌のノードをシグナリング キー: 上皮細胞の可塑性における Smad 信号統合。 Breast Cancer Research : BCR. Feb, 2012 | Pubmed ID: 22315972 共有結合二量化した組換えひと骨形成タンパク質 15 バリアント骨形成タンパク質受容体タイプ 1 B 卵巣顆粒膜細胞上キー細胞表面受容体として識別します。 Endocrinology. Jan, 2012 | Pubmed ID: 22294741 SMAD6 遺伝子における非同義のバリアントは、先天性心血管奇形にし向けます。 Human Mutation. Jan, 2012 | Pubmed ID: 22275001 ユビキチン固有プロテアーゼ 4 通行料のような/インターロイキン 1 受容体シグナリングを軽減し、生得的免疫活性化を調節します。 The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22262844 TGFβ シグナリングと心血管疾患。 International Journal of Biological Sciences. 2012 | Pubmed ID: 22253564 肝疾患の進行における TGF-β。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 22006249 BMP-7は、インテグリンβ(3)の発現の阻害を介して乳癌細胞のTGF-β誘導侵入を阻害する Cellular Oncology (Dordrecht). Feb, 2012 | Pubmed ID: 21935711 血管内皮細胞の可塑性 TGF-β の規制。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21866313 変形性関節症 TGF-β シグナル伝達の年齢依存性の改変。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21638205 TGF-β による内皮バリア機能の規制タイプ I 受容体 ALK5: 潜在的な役割の収縮のメカニズムと熱ショックタンパク質 90。 Journal of Cellular Physiology. Feb, 2012 | Pubmed ID: 21465483 ミオスタチン シグナル伝達細胞型特定の規制。 The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2011 | Pubmed ID: 22202673 マウス表皮における時空 Smad7 Transgene 誘発皮膚創傷治癒を加速します。 The American Journal of Pathology. Oct, 2011 | Pubmed ID: 21944279 GSK3β不活化は、C-MYBの機能を抑制することにより白血病細胞のアポトーシスを誘導 Molecular Biology of the Cell. Sep, 2011 | Pubmed ID: 21795403 2 つのユニークな TGF-β による制御血管新生タイプ I 受容体のシグナル伝達経路。 Histology and Histopathology. Sep, 2011 | Pubmed ID: 21751154 抗 TGF-β 療法の癌と線維化の探求。 Growth Factors (Chur, Switzerland). Aug, 2011 | Pubmed ID: 21718111 高架トランスフォーミング増殖因子 β およびマイトジェン活性化タンパク質キナーゼ経路デュピュイトラン病線維芽細胞の線維化の特徴を仲介します。 Fibrogenesis & Tissue Repair. 2011 | Pubmed ID: 21711521 シグナル伝達経路血管新生における TGF-β 受容体;抗血管新生療法のための新興ターゲット。 Current Pharmaceutical Biotechnology. May, 2011 | Pubmed ID: 21619534 骨形成タンパク質誘導骨芽細胞分化に及ぼす成長因子 β 変換の二相性効果。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2011 | Pubmed ID: 21611961 Tgfβ/Alk5 シグナリング胚大動脈内皮細胞におけるせん断応力誘起 Klf2 式が必要です。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2011 | Pubmed ID: 21604321 デュアル エクソン ミオスタチンとジストロフィン デュシェンヌ型筋ジストロフィーのスキップします。 BMC Medical Genomics. 2011 | Pubmed ID: 21507246 TGF-β シグナリング乳房癌細胞侵襲と骨転移の。 Journal of Mammary Gland Biology and Neoplasia. Jun, 2011 | Pubmed ID: 21494783 TGF β 1/ALK5 誘発単球移行 PI3K と P38 経路を含み、糖尿病によって否定的に影響はありません。 Cardiovascular Research. Aug, 2011 | Pubmed ID: 21478266 Fas関連因子1は、β-カテニンの分解を促進することによって、Wntシグナル伝達を拮抗 Molecular Biology of the Cell. May, 2011 | Pubmed ID: 21411632 一次繊毛の素数の欠如は、せん断誘発内皮から間葉移行 Circulation Research. Apr, 2011 | Pubmed ID: 21393577 Endoglin TGF-β/Smad1 強皮の繊維芽細胞のシグナル伝達を促進します。 Journal of Cellular Physiology. Dec, 2011 | Pubmed ID: 21344387 ALK2 変異患者にダウン症候群と先天性心臓欠陥します。 European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 Tgf β に対するストレス P38map 蛋白質キナーゼ-1 (MSK1) 細胞死を減衰するアクティブになります。 The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 TGF-β の動的役割がんで。 The Journal of Pathology. Jan, 2011 | Pubmed ID: 20957627 アクチビン a は非線維化の表現型平滑筋細胞の TGF-β とは対照的に誘導します。 Experimental Cell Research. Jan, 2011 | Pubmed ID: 20955695 BMPアンタゴニストは、筋原性分化を促進し、DMDモデルマウスにおけるジストロフィー表現型を改善する Neurobiology of Disease. Feb, 2011 | Pubmed ID: 20940052 TGF-β/Smad 経路マトリックスメタロプロテアーゼ 2 と 9 のアップ規制による乳房癌細胞浸潤回転楕円体浸潤モデル系に誘導します。 Breast Cancer Research and Treatment. Aug, 2011 | Pubmed ID: 20821046 二相性効果の成長因子 β タンパク質誘導骨形成に及ぼす骨芽細胞分化を変換します。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2010 | Pubmed ID: 21162084 BMP の構成活動の測定タイプ I 受容体。 Methods in Enzymology. 2010 | Pubmed ID: 21036238 Sclerostin 骨形成タンパク質と Wnt シグナル伝達経路の阻害の異なるモード。 The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20952383 血管の形態形成と疾患における TGF ベータ家族のメンバーによってシグナル。 Trends in Cell Biology. Sep, 2010 | Pubmed ID: 20656490 腫瘍細胞侵襲フロントで転写信号の統合。 Cell Cycle (Georgetown, Tex.). Jul, 2010 | Pubmed ID: 20647778 高架 Tgf β に対する Smad 実験 Pkd1 モデルと嚢胞腎の人間の患者でシグナリング。 The Journal of Pathology. Sep, 2010 | Pubmed ID: 20549648 In Situ 近接結紮検出 C 淳/AP 1 ダイマーの C-Jun/Fra1 錯体の積極的な乳がんがん細胞 in Vitro および in Vivo の増加レベルを明らかにします。 Molecular & Cellular Proteomics : MCP. Sep, 2010 | Pubmed ID: 20511396 マトリックス マトリックスメタロプロテアーゼ-14 (MT1 MMP)-仲介された Endoglin を流して腫瘍血管新生を阻害します。 Cancer Research. May, 2010 | Pubmed ID: 20424116 A1 アネキシン TGF-β のシグナル伝達を調節して基底様乳癌細胞の転移形成を促進します。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308542 TMEPAI 膜貫通型 TGF-β-誘導タンパク質、TGF β シグナリングに積極的に参加からの Smad 蛋白質治療中隔離します。 Molecular Cell. Jan, 2010 | Pubmed ID: 20129061 遺伝的および薬理学的にアクチビン受容体様キナーゼ 1 のターゲットと腫瘍の増殖および血管新生を損ないます。 The Journal of Experimental Medicine. Jan, 2010 | Pubmed ID: 20065063 骨形成因子 (BMP)-6 媒介キー残基の同定 Noggin 阻害に抵抗できます組み換え Bmp の優れたアゴニスト活性を。 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 雑種骨化性進行性にリンクされた ALK2 R206H 突然変異を与える構成アクティビティ BMP にタイプ I 受容体および BMP 誘導骨芽細胞分化および骨形成する間葉系細胞の感受性を高めます。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 5-アミノサリチル酸 TGF ベータ 1 大腸癌細胞のシグナル伝達を阻害します。 Cancer Letters. Jan, 2010 | Pubmed ID: 19541409 オートクリン骨形成タンパク質 9 アクチビン受容体様キナーゼ-2/Smad1/Smad4 を介して卵巣癌細胞の増殖を促進する信号します。 Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGFとTGFbeta I型受容体キナーゼの阻害剤は、相乗的にALPHA5インテグリンの発現を誘導することによって血管形成を促進 Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 Smad3 Nme マウス乳腺上皮細胞のシグナル伝達因子 β のキー非冗長調停者です。 Molecular Cancer Research : MCR. Aug, 2009 | Pubmed ID: 19671686 Endoglin ハプロ放射線誘発マウス腎臓における線維と毛細血管拡張症形成を低減します。 Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Sep, 2009 | Pubmed ID: 19576647 ドミナント ネガティブ ALK2 アレル先天性心臓欠陥を関連付けます。 Circulation. Jun, 2009 | Pubmed ID: 19506109 成長因子 β シグナリングと腫瘍血管新生の変換。 Frontiers in Bioscience : a Journal and Virtual Library. 2009 | Pubmed ID: 19482591 貧しい血管形成 ALK5 L45 ループ変異 Smad の活性化に欠陥を表現するノックイン マウスから胚では。 Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2009 | Pubmed ID: 19398960 電離放射線 PAI-1/ID-1 バランスをシフトし、内皮細胞の Notch をアクティブにします。 International Journal of Radiation Oncology, Biology, Physics. Feb, 2009 | Pubmed ID: 19147015 TGF-β シグナリング血管生物学および機能不全。 Cell Research. Jan, 2009 | Pubmed ID: 19114994 スキー内体コリプレッサー錯体 TGF ベータ ターゲット遺伝子、SMAD7、HDAC3 と PRMT5 を介しての基底の抑圧された状態を維持します。 Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jan, 2009 | Pubmed ID: 19032343 増殖因子ベータ誘導内皮間葉転換の変換: 心筋線維化への切り替えですか? Trends in Cardiovascular Medicine. Nov, 2008 | Pubmed ID: 19345316 Smad1 経路は全身性線維芽細胞が活性化され、イマチニブによる対象としています。 Arthritis and Rheumatism. Aug, 2008 | Pubmed ID: 18668566 骨形成タンパク質パスウェイ散発性大腸癌の大部分で不活化されます。 Gastroenterology. May, 2008 | Pubmed ID: 18471510 VE カドヘリン TGF β シグナリングの重要な内皮レギュレータです。 The EMBO Journal. Apr, 2008 | Pubmed ID: 18337748 び ALK1 ALK5/Smad3 シグナル伝達と細胞外マトリックス成分ひと軟骨細胞での発現を反対しています。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2008 | Pubmed ID: 18333754 L と S Endoglin は、差動 TGFbeta1 び ALK1 と ALK5 の L6E9 筋芽細胞を介したシグナル伝達を変調します。 Journal of Cell Science. Mar, 2008 | Pubmed ID: 18303046 Sclerostin 骨細胞由来骨形成を阻害する: 骨形成タンパク質および Wnt シグナル伝達におけるその役割。 The Journal of Bone and Joint Surgery. American Volume. Feb, 2008 | Pubmed ID: 18292354 Endoglin の血管新生と血管疾患では。 Angiogenesis. 2008 | Pubmed ID: 18283546 2 つの新しいタイプ II 受容体 BMP シグナル伝達を仲介し、ゼブラフィッシュの左右非対称性を確立する必要があります。 Developmental Biology. Mar, 2008 | Pubmed ID: 18222420 成長因子 β と創傷治癒人間真珠腫の変換。 The Laryngoscope. Jan, 2008 | Pubmed ID: 17989584 代償的なシグナリング卵黄嚢の血管系で削除マウスによる Tgf β 受容体の誘導。 Journal of Cell Science. Dec, 2007 | Pubmed ID: 18029401 腫瘍の進行と骨転移における TGF ベータと BMP7 相互作用 Clinical & Experimental Metastasis. 2007 | Pubmed ID: 18008174 Tgf β に対する血管の開発と病気のシグナルの細胞外のコントロール。 Nature Reviews. Molecular Cell Biology. Nov, 2007 | Pubmed ID: 17895899 迅速・高感度なバイオアッセイ骨形成タンパク質活性を測定します。 BMC Cell Biology. 2007 | Pubmed ID: 17880711 骨形成タンパク質 7 の開発と乳癌骨転移治療の。 Cancer Research. Sep, 2007 | Pubmed ID: 17875715 BMP7 推定レギュレータ、ひと前立腺上皮の恒常性の前立腺癌の骨転移の in Vivo での強力な阻害剤です。 The American Journal of Pathology. Sep, 2007 | Pubmed ID: 17724140 成長因子 β 変換による音波のハリネズミ メディエーターの誘導: Gli2 と Gli1 の発現 in Vitro および in Vivo の Smad3 依存性活性。 Cancer Research. Jul, 2007 | Pubmed ID: 17638910 ALK5 によるシグナル伝達を仲介する内皮細胞における TGF β 誘発 ET 1 式: 移行と増殖のための役割。 Journal of Cell Science. Apr, 2007 | Pubmed ID: 17376964 成長因子 β 受容体の種類に依存する石綿遺伝子プログラム Smad1 と ERK1/2 経路の活性化を介して媒介される変換。 The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17317656 TGF β 受容体/Smad シグナル伝達の負調節。 Current Opinion in Cell Biology. Apr, 2007 | Pubmed ID: 17317136 Aberrant Bmp Signaling and Notochord Delamination in the Pathogenesis of Esophageal Atresia Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2007 | Pubmed ID: 17260385 SOST 式萌芽期・新生児の心臓血管の開発中には大きな動脈に制限されています。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2007 | Pubmed ID: 17195180 KLF2 TGF-β Smad7 の誘導と AP 1 の阻害による内皮機能のシグナリングを抑制します。 Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2007 | Pubmed ID: 17194892 Wnt シグナルがない BMP シグナル Sclerostin BMP 誘導骨形成の阻害作用に関与しています。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2007 | Pubmed ID: 17032150 Smad6 のメチル化によるタンパク質アルギニン - N-メチルトランスフェラーゼ 1。 FEBS Letters. Dec, 2006 | Pubmed ID: 17118358 Endoglin に重要な役割血細胞による血管の修理でがあります。 Circulation. Nov, 2006 | Pubmed ID: 17088457 動力学および TGF ベータ経路の堅牢性を解明するために、レート方程式アプローチ。 Biophysical Journal. Dec, 2006 | Pubmed ID: 17012329 Smad7 誘起 β-カテニン劣化表皮付属物開発を変更します。 Developmental Cell. Sep, 2006 | Pubmed ID: 16950122 Id1 重要なメディエーター TGF β 誘発ラット肝星細胞の分化であります。 Hepatology (Baltimore, Md.). May, 2006 | Pubmed ID: 16628634 Smad7 とタンパク質ホスファターゼ 1 α は重要な決定要因 TGF-β が ALK1 内皮細胞内シグナリングの期間です。 BMC Cell Biology. 2006 | Pubmed ID: 16571110 腫瘍のサプレッサー細胞: Smad4 変換成長因子 β 誘発上皮間葉に転移と骨転移乳癌細胞のために必要です。 Cancer Research. Feb, 2006 | Pubmed ID: 16489022 成長因子 β シグナル伝達の血管新生と血管障害に変換します。 Chest. Dec, 2005 | Pubmed ID: 16373850 脱ユビキチン化酵素 UCH37 は、Smads と対話し、TGF-β のシグナル伝達を調節します。 Oncogene. Dec, 2005 | Pubmed ID: 16027725 生きたマウスの Smad2/3 依存型 TGF-β シグナル伝達のグローバル解析著名な組織特異応答傷害を明らかにします。 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 15972691 成長因子-beta1 骨に変換します。 Endocrine Reviews. Oct, 2005 | Pubmed ID: 15901668 SOST/sclerostin、骨形成の骨細胞由来の負レギュレータ。 Cytokine & Growth Factor Reviews. Jun, 2005 | Pubmed ID: 15869900 皮膚の自然免疫の新しいメカニズム: ASK1 を介したヒトケラチノ サイトの分化は、β デフェンシン, LL37, TLR2 の発現を調節します。 European Journal of Immunology. Jun, 2005 | Pubmed ID: 15864780 TGF β 受容体機能で内皮。 Cardiovascular Research. Feb, 2005 | Pubmed ID: 15664386 Endoglin 変異マウスの卵黄嚢の血管系でによる Tgf β に対するシグナル伝達不良のパラクリン: 遺伝性出血性毛細血管拡張症のためのパラダイム。 Development (Cambridge, England). Dec, 2004 | Pubmed ID: 15548578 Endoglin は、内皮細胞の増殖および TGF-β が ALK1 シグナル伝達を促進します。 The EMBO Journal. Oct, 2004 | Pubmed ID: 15385967 結合組織成長因子の発現とマウス間のシグナリング Smad 開発と心筋梗塞を心します。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2004 | Pubmed ID: 15376321 Smad1 と Smad5 in Vivo での時空間的活性化: Smad 蛋白質の転写活性を監視します。 Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331632 RLP 小説 Ras 様タンパク質悪影響 TGF-β によって誘導される転写活性を調節する、即時早期の変形成長因子 β (TGF ベータ版) ターゲット遺伝子です。 The Biochemical Journal. Oct, 2004 | Pubmed ID: 15239668 TGF ベータ Smad シグナル伝達の新しい洞察力。 Trends in Biochemical Sciences. May, 2004 | Pubmed ID: 15130563 Sclerostin は、骨の形成がない古典的な BMP 拮抗薬の骨細胞を表明したの負レギュレータです。 The Journal of Experimental Medicine. Mar, 2004 | Pubmed ID: 15024046 神経成長因子 PC12 細胞における Smad 経路の活性化を仲介します。 European Journal of Biochemistry / FEBS. Mar, 2004 | Pubmed ID: 15009204 による骨形成タンパク質受容体細胞の運命を制御します。 Molecular and Cellular Endocrinology. Dec, 2003 | Pubmed ID: 14656483 アクチビン受容体様キナーゼ (アルク) 1 横 Tgf β に対する/ALK5 シグナリングは拮抗メディエーターです。 Molecular Cell. Oct, 2003 | Pubmed ID: 14580334 Tgf β に対する家族による間葉系幹細胞分化を制御します。 Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association. 2003 | Pubmed ID: 14557946 骨芽細胞分化における骨形成タンパク質のシグナル伝達。 The Journal of Bone and Joint Surgery. American Volume. 2003 | Pubmed ID: 12925607 遺伝子配列解析における骨形成タンパク質受容体による骨芽細胞分化を型します。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2003 | Pubmed ID: 12854827 Smad7 肝星細胞およびラットにおける肝線維化の活性化を防ぎます。 Gastroenterology. Jul, 2003 | Pubmed ID: 12851882 核因子 YY1 変換増殖因子ベータと骨形成タンパク質による細胞分化を抑制します。 Molecular and Cellular Biology. Jul, 2003 | Pubmed ID: 12808092 リン酸化 Smad2 の分布 TGF ベータ配位子マウス開発の標的組織を識別します。 Gene Expression Patterns : GEP. Jun, 2003 | Pubmed ID: 12799085 DSmurf が選択的にモロッコ ディルハム、decapentaplegic 活性が低下し、その過剰発現脚成虫原基の発達を中断します。 The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12754252 Smad タンパク質および TGF ベータで血管におけるシグナル平滑筋細胞。 International Journal of Molecular Medicine. May, 2003 | Pubmed ID: 12684705 合成トリテルペノイド変換増殖因子ベータ/Smad シグナリングを強化します。 Cancer Research. Mar, 2003 | Pubmed ID: 12649201 成長因子-beta1 (TGF ベータ版) の変換-前立腺癌細胞のアポトーシス誘導は、TGF ベータ活性化キナーゼ 1 とマイトジェン活性化タンパク質キナーゼのキナーゼ 3 による P38 の Smad7 依存性の活性化を伴います。 Molecular Biology of the Cell. Feb, 2003 | Pubmed ID: 12589052 成長分化因子 9 Smad2 活性とひと顆粒膜黄体細胞におけるインヒビン B 生産を誘導します。 The Journal of Clinical Endocrinology and Metabolism. Feb, 2003 | Pubmed ID: 12574210 成長因子 β 1 の変異 Camurati エンゲルマン病リード増加活性化または変異タンパク質の分泌を変えることによって信号に変換します。 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12493741 成長因子 β 変換における Smad 要件の解明は受容体による応答を入力します。 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12446693 BMP 経路は、耳のカプセル形成に関与して上皮間葉で発展途上の鶏の内耳の信号です。 Developmental Biology. Nov, 2002 | Pubmed ID: 12435365 刺激による骨形成タンパク質 Id1 発現の十分なと骨形成タンパク質誘起活性内皮細胞のために必要です。 Circulation. Oct, 2002 | Pubmed ID: 12390958 原性タンパク質 (OP-1) とその受容体でのウサギ関節軟骨の局在。 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2002 | Pubmed ID: 12364567 インヒビン B 生産卵巣顆粒膜細胞の誘導における経路 Smad 蛋白質シグナリング アクチビンと骨形成タンパク質の関与。 Molecular and Cellular Endocrinology. Sep, 2002 | Pubmed ID: 12354674 骨形成タンパク質/気管支の上皮細胞の中に気道炎症シグナル Smad の活性化。 American Journal of Respiratory Cell and Molecular Biology. Aug, 2002 | Pubmed ID: 12151307 Smad7 の過剰発現は、複数の上皮組織における重度病理学的変化の結果します。 The EMBO Journal. Jun, 2002 | Pubmed ID: 12032071 成長因子 β のシグナル伝達を変換します。 Journal of Leukocyte Biology. May, 2002 | Pubmed ID: 11994497 内皮細胞を介して 2 つの個別のアクティベーションの状態を分散 TGF-β 型受容体。 The EMBO Journal. Apr, 2002 | Pubmed ID: 11927558 Smad タンパク質による細胞増殖の制御。 Journal of Cellular Physiology. Apr, 2002 | Pubmed ID: 11920677 欠乏の Smad7 式: 強皮症の推定される分子欠陥。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904440 行動範囲の BMP その N 末端塩基性アミノ酸コアによって定義されます。 Current Biology : CB. Feb, 2002 | Pubmed ID: 11839272 ガータ 3 と Smad3 の物理的および機能的なインタラクション ガータ標的遺伝子の TGF-β 調節できます。 Current Biology : CB. Jan, 2002 | Pubmed ID: 11790301 オートクリン TGF β シグナリングの一時的な中断は、強化された生存と単一のプリミティブ人間造血前駆細胞の潜在的な増殖に します。 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777969 同定と機能解析 Id1 プロモーター内の個別の批判的に重要な骨形成タンパク質固有の応答要素の。 The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11729207 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 TGF β媒介性間葉転移(EndMT)およびCRISPR/Cas9遺伝子編集を用いたEndMTエフェクターの機能評価 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 생물학 乳がんおよび正常細胞におけるTGF-βシグナル伝達とTGF β誘発性上皮間葉間質転移の研究 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 암 연구학 胚ゼブラフィッシュにおけるヒト乳癌細胞の浸潤挙動 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 암 연구학 TGF -β誘発性浸潤を測定する回転楕円体アッセイ Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 의학
TGF β媒介性間葉転移(EndMT)およびCRISPR/Cas9遺伝子編集を用いたEndMTエフェクターの機能評価 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 생물학
乳がんおよび正常細胞におけるTGF-βシグナル伝達とTGF β誘発性上皮間葉間質転移の研究 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 암 연구학
胚ゼブラフィッシュにおけるヒト乳癌細胞の浸潤挙動 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 암 연구학
TGF -β誘発性浸潤を測定する回転楕円体アッセイ Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 의학