Robert H. Edwards Departments of Neurology and Physiology University of California School of Medicine, San Francisco Biography Publications Institution JoVE Articles Robert H. Edwards has not added a biography. If you are Robert H. Edwards and would like to personalize this page please email our Author Liaison for assistance. Publications Dopamine Dysregulation in a Mouse Model of Paroxysmal Nonkinesigenic Dyskinesia The Journal of Clinical Investigation. Feb, 2012 | Pubmed ID: 22214848 Vesicular and Plasma Membrane Transporters for Neurotransmitters Cold Spring Harbor Perspectives in Biology. 2012 | Pubmed ID: 22199021 Neurotransmitter Corelease: Mechanism and Physiological Role Annual Review of Physiology. Mar, 2012 | Pubmed ID: 22054239 Presynaptic Regulation of Quantal Size: K+/H+ Exchange Stimulates Vesicular Glutamate Transport Nature Neuroscience. Oct, 2011 | Pubmed ID: 21874016 Genetic Targeting and Physiological Features of VGLUT3+ Amacrine Cells Visual Neuroscience. Sep, 2011 | Pubmed ID: 21864449 V-SNARE Composition Distinguishes Synaptic Vesicle Pools Neuron. Aug, 2011 | Pubmed ID: 21835344 Expression of Vesicular Glutamate Transporters Type 1 and 2 in Sensory and Autonomic Neurons Innervating the Mouse Colorectum The Journal of Comparative Neurology. Nov, 2011 | Pubmed ID: 21800314 Pathway-specific Genetic Attenuation of Glutamate Release Alters Select Features of Competition-based Visual Circuit Refinement Neuron. Jul, 2011 | Pubmed ID: 21791283 Cholinergic Interneurons Mediate Fast VGluT3-dependent Glutamatergic Transmission in the Striatum PloS One. 2011 | Pubmed ID: 21544206 Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein Alpha-synuclein The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21489994 RNAi Screen Identifies a Role for Adaptor Protein AP-3 in Sorting to the Regulated Secretory Pathway The Journal of Cell Biology. Dec, 2010 | Pubmed ID: 21149569 VGLUT2 Expression in Primary Afferent Neurons is Essential for Normal Acute Pain and Injury-induced Heat Hypersensitivity Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21135246 Metabolic Control of Vesicular Glutamate Transport and Release Neuron. Oct, 2010 | Pubmed ID: 20920794 Dopaminergic Terminals in the Nucleus Accumbens but Not the Dorsal Striatum Corelease Glutamate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20554874 Vesicular Monoamine and Glutamate Transporters Select Distinct Synaptic Vesicle Recycling Pathways The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20534840 Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease in Vivo Neuron. Mar, 2010 | Pubmed ID: 20223200 The Behavior of Alpha-synuclein in Neurons Movement Disorders : Official Journal of the Movement Disorder Society. 2010 | Pubmed ID: 20187244 Increased Expression of Alpha-synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering After Endocytosis Neuron. Jan, 2010 | Pubmed ID: 20152114 Localized Topological Changes of the Plasma Membrane Upon Exocytosis Visualized by Polarized TIRFM The Journal of Cell Biology. Feb, 2010 | Pubmed ID: 20142424 Glutamate Co-release at GABA/glycinergic Synapses is Crucial for the Refinement of an Inhibitory Map Nature Neuroscience. Feb, 2010 | Pubmed ID: 20081852 Injury-induced Mechanical Hypersensitivity Requires C-low Threshold Mechanoreceptors Nature. Dec, 2009 | Pubmed ID: 19915548 Fluorescent False Neurotransmitters Visualize Dopamine Release from Individual Presynaptic Terminals Science (New York, N.Y.). Jun, 2009 | Pubmed ID: 19423778 Synaptic and Extrasynaptic Factors Governing Glutamatergic Retinal Waves Neuron. Apr, 2009 | Pubmed ID: 19409268 Interplay Between Cytosolic Dopamine, Calcium, and Alpha-synuclein Causes Selective Death of Substantia Nigra Neurons Neuron. Apr, 2009 | Pubmed ID: 19409267 Vesicular Glutamate and GABA Transporters Sort to Distinct Sets of Vesicles in a Population of Presynaptic Terminals Cerebral Cortex (New York, N.Y. : 1991). Jan, 2009 | Pubmed ID: 18502731 Optical Reporters for the Conformation of Alpha-synuclein Reveal a Specific Interaction with Mitochondria The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008 | Pubmed ID: 19020024 Fast Subplasma Membrane Ca2+ Transients Control Exo-endocytosis of Synaptic-like Microvesicles in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2008 | Pubmed ID: 18784293 Vesicular Glutamate Transporter 3-immunoreactive Pericellular Baskets Ensheath a Distinct Population of Neurons in the Lateral Septum Journal of Chemical Neuroanatomy. Dec, 2008 | Pubmed ID: 18611437 Expression and Function of the Rat Vesicular Monoamine Transporter 2 American Journal of Physiology. Cell Physiology. Apr, 2008 | Pubmed ID: 18287335 Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3 Neuron. Jan, 2008 | Pubmed ID: 18215623 Pharmacology of Neurotransmitter Transport into Secretory Vesicles Handbook of Experimental Pharmacology. 2008 | Pubmed ID: 18064412 Vesicular Neurotransmitter Transporters As Targets for Endogenous and Exogenous Toxic Substances Annual Review of Pharmacology and Toxicology. 2008 | Pubmed ID: 17883368 The Neurotransmitter Cycle and Quantal Size Neuron. Sep, 2007 | Pubmed ID: 17880890 Physiology Versus Pathology in Parkinson's Disease Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17623781 Vesicular Glutamate Transporter 1 is Required for Photoreceptor Synaptic Signaling but Not for Intrinsic Visual Functions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2007 | Pubmed ID: 17611277 Thyronamines Inhibit Plasma Membrane and Vesicular Monoamine Transport ACS Chemical Biology. Jun, 2007 | Pubmed ID: 17530732 Do Different Endocytic Pathways Make Different Synaptic Vesicles? Current Opinion in Neurobiology. Jun, 2007 | Pubmed ID: 17449236 Alpha-synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2006 | Pubmed ID: 17108165 Secretion of L-glutamate from Osteoclasts Through Transcytosis The EMBO Journal. Sep, 2006 | Pubmed ID: 16957773 Alpha-synuclein Overexpression Increases Cytosolic Catecholamine Concentration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2006 | Pubmed ID: 16957086 Synaptic Vesicles: Half Full or Half Empty? Neuron. Sep, 2006 | Pubmed ID: 16950150 Distinct Endocytic Pathways Control the Rate and Extent of Synaptic Vesicle Protein Recycling Neuron. Jul, 2006 | Pubmed ID: 16815333 Distribution of Vesicular Glutamate Transporters 1 and 2 in the Rat Spinal Cord, with a Note on the Spinocervical Tract The Journal of Comparative Neurology. Aug, 2006 | Pubmed ID: 16786558 Vesicular Glutamate Transporter 3 (VGLUT3) Identifies Spatially Segregated Excitatory Terminals in the Rat Substantia Nigra The European Journal of Neuroscience. Feb, 2006 | Pubmed ID: 16519671 PharmGKB Submission Update: VI. PMT Submissions of Genetic Variations in Neurotransmitter Transporters (SLC6, SLC17, and SLC18) to the PharmGKB Network Pharmacological Reviews. Mar, 2006 | Pubmed ID: 16507879 Structural Variants in the Vesicular Monoamine Transporter Do Not Contribute to Sporadic Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2006 | Pubmed ID: 16450345 Changes in Purinergic Signaling After Cerebral Injury -- Involvement of Glutamatergic Mechanisms? International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Apr-May, 2006 | Pubmed ID: 16387466 Functional Implications of Neurotransmitter Co-release: Glutamate and GABA Share the Load Current Opinion in Pharmacology. Feb, 2006 | Pubmed ID: 16359920 Neural Activity Controls the Synaptic Accumulation of Alpha-synuclein The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2005 | Pubmed ID: 16306404 Sorting of Vesicular Monoamine Transporter 2 to the Regulated Secretory Pathway Confers the Somatodendritic Exocytosis of Monoamines Neuron. Nov, 2005 | Pubmed ID: 16301178 A Combinatorial Code for the Interaction of Alpha-synuclein with Membranes The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 16020543 Antidepressants and the Monoamine Masquerade Neuron. Apr, 2005 | Pubmed ID: 15820686 Normal Biogenesis and Cycling of Empty Synaptic Vesicles in Dopamine Neurons of Vesicular Monoamine Transporter 2 Knockout Mice Molecular Biology of the Cell. Jan, 2005 | Pubmed ID: 15496457 Expression of the Vesicular Glutamate Transporters During Development Indicates the Widespread Corelease of Multiple Neurotransmitters The Journal of Comparative Neurology. Dec, 2004 | Pubmed ID: 15515175 The Effect of Rare Human Sequence Variants on the Function of Vesicular Monoamine Transporter 2 Pharmacogenetics. Sep, 2004 | Pubmed ID: 15475732 Evidence That Certain Retinal Bipolar Cells Use Both Glutamate and GABA The Journal of Comparative Neurology. Oct, 2004 | Pubmed ID: 15368537 Vesicular Glutamate Transporter 3 Expression Identifies Glutamatergic Amacrine Cells in the Rodent Retina The Journal of Comparative Neurology. Sep, 2004 | Pubmed ID: 15329888 Lipid Rafts Mediate the Synaptic Localization of Alpha-synuclein The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004 | Pubmed ID: 15282274 Endocannabinoid-independent Retrograde Signaling at Inhibitory Synapses in Layer 2/3 of Neocortex: Involvement of Vesicular Glutamate Transporter 3 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004 | Pubmed ID: 15163690 Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites Science (New York, N.Y.). Jun, 2004 | Pubmed ID: 15118123 VGLUTs Define Subsets of Excitatory Neurons and Suggest Novel Roles for Glutamate Trends in Neurosciences. Feb, 2004 | Pubmed ID: 15102489 Electrochemical Monitoring of Transport by a Vesicular Monoamine Transporter Expressed in Xenopus Oocytes Journal of Neuroscience Methods. Feb, 2004 | Pubmed ID: 14757360 Organic Anion Transport is the Primary Function of the SLC17/type I Phosphate Transporter Family Pflügers Archiv : European Journal of Physiology. Feb, 2004 | Pubmed ID: 12811560 Complementary Distribution of Type 1 Cannabinoid Receptors and Vesicular Glutamate Transporter 3 in Basal Forebrain Suggests Input-specific Retrograde Signalling by Cholinergic Neurons The European Journal of Neuroscience. Oct, 2003 | Pubmed ID: 14622230 Expression of Plasma Membrane GABA Transporters but Not of the Vesicular GABA Transporter in Dentate Granule Cells After Kainic Acid Seizures Hippocampus. 2003 | Pubmed ID: 14620876 Plasma Membrane and Vesicular Glutamate Transporter MRNAs/proteins in Hypothalamic Neurons That Regulate Body Weight The European Journal of Neuroscience. Sep, 2003 | Pubmed ID: 12956725 Complementary Distribution of Vesicular Glutamate Transporters 1 and 2 in the Nucleus Accumbens of Rat: Relationship to Calretinin-containing Extrinsic Innervation and Calbindin-immunoreactive Neurons The Journal of Comparative Neurology. Oct, 2003 | Pubmed ID: 12926012 Cellular Localization of Three Vesicular Glutamate Transporter MRNAs and Proteins in Rat Spinal Cord and Dorsal Root Ganglia Synapse (New York, N.Y.). Nov, 2003 | Pubmed ID: 12923814 The H+-coupled Electrogenic Lysosomal Amino Acid Transporter LYAAT1 Localizes to the Axon and Plasma Membrane of Hippocampal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2003 | Pubmed ID: 12598615 Postnatal Development of the Glutamate Vesicular Transporter VGLUT1 in Rat Cerebral Cortex Brain Research. Developmental Brain Research. Feb, 2003 | Pubmed ID: 12586437 Vesicular Neurotransmitter Transporter Expression in Developing Postnatal Rodent Retina: GABA and Glycine Precede Glutamate The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003 | Pubmed ID: 12533612 The Identification of Vesicular Glutamate Transporter 3 Suggests Novel Modes of Signaling by Glutamate Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12388773 Methamphetamine-induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002 | Pubmed ID: 12388602 Cell-specific Expression of the Glutamine Transporter SN1 Suggests Differences in Dependence on the Glutamine Cycle The European Journal of Neuroscience. May, 2002 | Pubmed ID: 12059969 The Glutamine Commute: Take the N Line and Transfer to the A The Journal of Cell Biology. Apr, 2002 | Pubmed ID: 11980913 Regulation of the Glutamine Transporter SN1 by Extracellular PH and Intracellular Sodium Ions The Journal of Physiology. Feb, 2002 | Pubmed ID: 11850497 Glutamine Uptake by Neurons: Interaction of Protons with System a Transporters The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756489 متصور النسخة الدوبامين في محطات قبل المشبكي فردية مع FFNs Hui Zhang1,2, Niko G. Gubernator3,4, Minerva Yue1, Roland G. W. Staal1, Eugene V. Mosharov1, Daniela Pereira1, Vojtech Balsanek3, Paul A. Vadola3, Bipasha Mukherjee5, Robert H. Edwards5, David Sulzer1,2,6, Dalibor Sames3 1Departments of Neurology, Columbia University, 2Departments of Psychiatry and Pharmacology, Columbia University, 3Department of Chemistry, Columbia University, 4eMolecules, Inc., 5Departments of Neurology and Physiology, University of California School of Medicine, San Francisco, 6Division of Molecular Therapeutics, New York Psychiatric Institute JoVE 1562 생물학
متصور النسخة الدوبامين في محطات قبل المشبكي فردية مع FFNs Hui Zhang1,2, Niko G. Gubernator3,4, Minerva Yue1, Roland G. W. Staal1, Eugene V. Mosharov1, Daniela Pereira1, Vojtech Balsanek3, Paul A. Vadola3, Bipasha Mukherjee5, Robert H. Edwards5, David Sulzer1,2,6, Dalibor Sames3 1Departments of Neurology, Columbia University, 2Departments of Psychiatry and Pharmacology, Columbia University, 3Department of Chemistry, Columbia University, 4eMolecules, Inc., 5Departments of Neurology and Physiology, University of California School of Medicine, San Francisco, 6Division of Molecular Therapeutics, New York Psychiatric Institute JoVE 1562 생물학