Robert L. Medcalf Australian Centre for Blood Diseases Monash University Biography Publications Institution JoVE Articles Robert L. Medcalf has not added a biography. If you are Robert L. Medcalf and would like to personalize this page please email our Author Liaison for assistance. Publications Tissue-type Plasminogen Activator is an Extracellular Mediator of Purkinje Cell Damage and Altered Gait Experimental Neurology. Nov, 2013 | Pubmed ID: 23939410 Plasminogen-stimulated Inflammatory Cytokine Production by Airway Smooth Muscle Cells is Regulated by Annexin A2 American Journal of Respiratory Cell and Molecular Biology. Nov, 2013 | Pubmed ID: 23721211 Nucleocytoplasmic Coagulation: an Injury-induced Aggregation Event That Disulfide Crosslinks Proteins and Facilitates Their Removal by Plasmin Cell Reports. Oct, 2012 | Pubmed ID: 23041318 Tissue Plasminogen Activator Does Not Alter Development of Acquired Epilepsy Epilepsia. Nov, 2012 | Pubmed ID: 22957978 The Tissue-type Plasminogen Activator-plasminogen Activator Inhibitor 1 Complex Promotes Neurovascular Injury in Brain Trauma: Evidence from Mice and Humans Brain : a Journal of Neurology. Nov, 2012 | Pubmed ID: 22822039 Tissue-type Plasminogen Activator Regulates the Neuronal Uptake of Glucose in the Ischemic Brain The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012 | Pubmed ID: 22815500 Plasminogen Activation and Thrombolysis for Ischemic Stroke International Journal of Stroke : Official Journal of the International Stroke Society. Jul, 2012 | Pubmed ID: 22463085 Role of Histone Acetylation in the Stimulatory Effect of Valproic Acid on Vascular Endothelial Tissue-type Plasminogen Activator Expression PloS One. 2012 | Pubmed ID: 22363677 T-PA-specific Modulation of a Human Blood-brain Barrier Model Involves Plasmin-mediated Activation of the Rho Kinase Pathway in Astrocytes Blood. May, 2012 | Pubmed ID: 22262761 Desmoteplase: Discovery, Insights and Opportunities for Ischaemic Stroke British Journal of Pharmacology. Jan, 2012 | Pubmed ID: 21627637 Plasminogen Activation-based Thrombolysis for Ischaemic Stroke: the Diversity of Targets May Demand New Approaches Current Drug Targets. Nov, 2011 | Pubmed ID: 21707475 Plasminogen Activator Inhibitor Type 2: Still an Enigmatic Serpin but a Model for Gene Regulation Methods in Enzymology. 2011 | Pubmed ID: 21683251 Novel Role of Platelets in Mediating Inflammatory Responses and Ventricular Rupture or Remodeling Following Myocardial Infarction Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2011 | Pubmed ID: 21252067 Thrombin-induced Activation of Astrocytes in Mixed Rat Hippocampal Cultures is Inhibited by Soluble Thrombomodulin Brain Research. Mar, 2011 | Pubmed ID: 21241677 The Plasminogen Activator Inhibitor 2 Transcript is Destabilized Via a Multi-component 3' UTR Localized Adenylate and Uridylate-rich Instability Element in an Analogous Manner to Cytokines and Oncogenes The FEBS Journal. Mar, 2010 | Pubmed ID: 20392207 Reduced Phosphoinositide 3-kinase (p110alpha) Activation Increases the Susceptibility to Atrial Fibrillation The American Journal of Pathology. Sep, 2009 | Pubmed ID: 19679877 A Nonfibrin Macromolecular Cofactor for TPA-mediated Plasmin Generation Following Cellular Injury Blood. Aug, 2009 | Pubmed ID: 19584397 Tissue-type Plasminogen Activator Requires a Co-receptor to Enhance NMDA Receptor Function Journal of Neurochemistry. Nov, 2008 | Pubmed ID: 18796005 Desmoteplase-mediated Plasminogen Activation and Clot Lysis Are Inhibited by the Lysine Analogue Tranexamic Acid Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Jun, 2008 | Pubmed ID: 18469556 Two Conserved Regions Within the Tissue-type Plasminogen Activator Gene Promoter Mediate Regulation by Brain-derived Neurotrophic Factor The FEBS Journal. May, 2007 | Pubmed ID: 17419735 Stage Specific Gene Expression of Serpins and Their Cognate Proteases During Myeloid Differentiation British Journal of Haematology. Dec, 2006 | Pubmed ID: 17107353 Oncostatin M is a Neuroprotective Cytokine That Inhibits Excitotoxic Injury in Vitro and in Vivo FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2006 | Pubmed ID: 17023520 SerpinB2 is an Inducible Host Factor Involved in Enhancing HIV-1 Transcription and Replication The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16923810 Tissue-type Plasminogen Activator: a Multifaceted Modulator of Neurotransmission and Synaptic Plasticity Neuron. Jun, 2006 | Pubmed ID: 16731507 The Undecided Serpin. The Ins and Outs of Plasminogen Activator Inhibitor Type 2 The FEBS Journal. Oct, 2005 | Pubmed ID: 16176260 Meet the Serpins The FEBS Journal. Oct, 2005 | Pubmed ID: 16176257 Regulation of Protease and Protease Inhibitor Gene Expression: the Role of the 3'-UTR and Lessons from the Plasminogen Activating System Progress in Nucleic Acid Research and Molecular Biology. 2005 | Pubmed ID: 16164975 Vampire Bat Salivary Plasminogen Activator (desmoteplase) Inhibits Tissue-type Plasminogen Activator-induced Potentiation of Excitotoxic Injury Stroke; a Journal of Cerebral Circulation. Jun, 2005 | Pubmed ID: 15879331 Transcriptional and Posttranscriptional Regulation of the Plasminogen Activator System Thrombosis and Haemostasis. Apr, 2005 | Pubmed ID: 15841310 The Relationship Between the Prothrombin Upstream Sequence Element and the G20210A Polymorphism: the Influence of a Competitive Environment for MRNA 3'-end Formation Nucleic Acids Research. 2005 | Pubmed ID: 15718300 The T-PA -7351C>T Enhancer Polymorphism Decreases Sp1 and Sp3 Protein Binding Affinity and Transcriptional Responsiveness to Retinoic Acid Blood. Feb, 2005 | Pubmed ID: 15466927 The Structure of the Zinc Finger Domain from Human Splicing Factor ZNF265 Fold The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12657633 Inherent Instability of Plasminogen Activator Inhibitor Type 2 MRNA is Regulated by Tristetraprolin The Journal of Biological Chemistry. Apr, 2003 | Pubmed ID: 12578825 Vampire Bat Salivary Plasminogen Activator (desmoteplase): a Unique Fibrinolytic Enzyme That Does Not Promote Neurodegeneration Stroke; a Journal of Cerebral Circulation. Feb, 2003 | Pubmed ID: 12574572 Prothrombin G20210A is a Bifunctional Gene Polymorphism Thrombosis and Haemostasis. May, 2002 | Pubmed ID: 12038788 Plasminogen Activator Inhibitor Type 2: a Regulator of Monocyte Proliferation and Differentiation Blood. Apr, 2002 | Pubmed ID: 11929770 Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier Be'eri Niego1, Robert L. Medcalf1 1Australian Centre for Blood Diseases, Monash University JoVE 50934 생체공학
Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier Be'eri Niego1, Robert L. Medcalf1 1Australian Centre for Blood Diseases, Monash University JoVE 50934 생체공학