Rohini Kuner Institute for Pharmacology University of Heidelberg Biography Publications Institution JoVE Articles Rohini Kuner has not added a biography. If you are Rohini Kuner and would like to personalize this page please email our Author Liaison for assistance. Publications Sources of Individual Variability: MiRNAs That Predispose to Neuropathic Pain Identified Using Genome-wide Sequencing Molecular Pain. Mar, 2014 | Pubmed ID: 24642266 Genetic Dissection of Plexin Signaling in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24469813 BKCa Channels Expressed in Sensory Neurons Modulate Inflammatory Pain in Mice Pain. Mar, 2014 | Pubmed ID: 24333777 Gq Rather Than G11 Preferentially Mediates Nociceptor Sensitization Molecular Pain. 2013 | Pubmed ID: 24156378 MicroRNAs in Nociceptive Circuits As Predictors of Future Clinical Applications Frontiers in Molecular Neuroscience. 2013 | Pubmed ID: 24151455 Transcriptional Mechanisms Underlying Sensitization of Peripheral Sensory Neurons by Granulocyte-/granulocyte-macrophage Colony Stimulating Factors Molecular Pain. 2013 | Pubmed ID: 24067145 Genome-wide Identification and Functional Analyses of MicroRNA Signatures Associated with Cancer Pain EMBO Molecular Medicine. Nov, 2013 | Pubmed ID: 24039159 A Novel Biological Role for the Phospholipid Lysophosphatidylinositol in Nociceptive Sensitization Via Activation of Diverse G-protein Signalling Pathways in Sensory Nerves in Vivo Pain. Dec, 2013 | Pubmed ID: 23973358 Pain Hypersensitivity Mechanisms at a Glance Disease Models & Mechanisms. Jul, 2013 | Pubmed ID: 23828645 Cannabinoid 1 Receptors in Keratinocytes Modulate Proinflammatory Chemokine Secretion and Attenuate Contact Allergic Inflammation Journal of Immunology (Baltimore, Md. : 1950). May, 2013 | Pubmed ID: 23585676 Nuclear Calcium Signaling in Spinal Neurons Drives a Genomic Program Required for Persistent Inflammatory Pain Neuron. Jan, 2013 | Pubmed ID: 23312515 Pain in Experimental Autoimmune Encephalitis: a Comparative Study Between Different Mouse Models Journal of Neuroinflammation. 2012 | Pubmed ID: 23039175 Dynamin 2 Mutations in Charcot-Marie-Tooth Neuropathy Highlight the Importance of Clathrin-mediated Endocytosis in Myelination Brain : a Journal of Neurology. May, 2012 | Pubmed ID: 22451505 Presynaptically Localized Cyclic GMP-dependent Protein Kinase 1 is a Key Determinant of Spinal Synaptic Potentiation and Pain Hypersensitivity PLoS Biology. 2012 | Pubmed ID: 22427743 Gα(q/11) Signaling Tonically Modulates Nociceptor Function and Contributes to Activity-dependent Sensitization Pain. Jan, 2012 | Pubmed ID: 22071319 Presynaptic Alpha2-GABAA Receptors in Primary Afferent Depolarization and Spinal Pain Control The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21632935 Homer1a Signaling in the Amygdala Counteracts Pain-related Synaptic Plasticity, MGluR1 Function and Pain Behaviors Molecular Pain. 2011 | Pubmed ID: 21595930 Peripheral Calcium-permeable AMPA Receptors Regulate Chronic Inflammatory Pain in Mice The Journal of Clinical Investigation. Apr, 2011 | Pubmed ID: 21383497 Follistatin-like 1 Suppresses Sensory Afferent Transmission by Activating Na+,K+-ATPase Neuron. Mar, 2011 | Pubmed ID: 21382556 Genetic Evidence for Involvement of Neuronally Expressed S1P₁ Receptor in Nociceptor Sensitization and Inflammatory Pain PloS One. 2011 | Pubmed ID: 21359147 Hematopoietic Colony-stimulating Factors: New Players in Tumor-nerve Interactions Journal of Molecular Medicine (Berlin, Germany). Apr, 2011 | Pubmed ID: 21079906 Central Mechanisms of Pathological Pain Nature Medicine. Nov, 2010 | Pubmed ID: 20948531 R-flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids PloS One. 2010 | Pubmed ID: 20498712 An Improved Behavioural Assay Demonstrates That Ultrasound Vocalizations Constitute a Reliable Indicator of Chronic Cancer Pain and Neuropathic Pain Molecular Pain. 2010 | Pubmed ID: 20346101 Dissecting the Functional Significance of Endothelin A Receptors in Peripheral Nociceptors in Vivo Via Conditional Gene Deletion Pain. Feb, 2010 | Pubmed ID: 19879049 Conditional Gene Deletion Reveals Functional Redundancy of GABAB Receptors in Peripheral Nociceptors in Vivo Molecular Pain. 2009 | Pubmed ID: 19925671 A Key Role for Gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19864560 Inhibitor KappaB Kinase Beta Deficiency in Primary Nociceptive Neurons Increases TRP Channel Sensitivity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19828806 The Semaphorin 4D-plexin-B Signalling Complex Regulates Dendritic and Axonal Complexity in Developing Neurons Via Diverse Pathways The European Journal of Neuroscience. Oct, 2009 | Pubmed ID: 19788569 Mice Lacking Plexin-B3 Display Normal CNS Morphology and Behaviour Molecular and Cellular Neurosciences. Dec, 2009 | Pubmed ID: 19699796 Roles of the AMPA Receptor Subunit GluA1 but Not GluA2 in Synaptic Potentiation and Activation of ERK in the Anterior Cingulate Cortex Molecular Pain. 2009 | Pubmed ID: 19664265 Hematopoietic Colony-stimulating Factors Mediate Tumor-nerve Interactions and Bone Cancer Pain Nature Medicine. Jul, 2009 | Pubmed ID: 19525966 Activity-dependent Potentiation of Calcium Signals in Spinal Sensory Networks in Inflammatory Pain States Pain. Nov, 2008 | Pubmed ID: 18926636 A Functional Role for Semaphorin 4D/plexin B1 Interactions in Epithelial Branching Morphogenesis During Organogenesis Development (Cambridge, England). Oct, 2008 | Pubmed ID: 18799546 Genetic Deletion of Synapsin II Reduces Neuropathic Pain Due to Reduced Glutamate but Increased GABA in the Spinal Cord Dorsal Horn Pain. Oct, 2008 | Pubmed ID: 18701217 Mechanisms of Compartmentalized Expression of Mrg Class G-protein-coupled Sensory Receptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2008 | Pubmed ID: 18171930 Cannabinoids Mediate Analgesia Largely Via Peripheral Type 1 Cannabinoid Receptors in Nociceptors Nature Neuroscience. Jul, 2007 | Pubmed ID: 17558404 Plexin-B2, but Not Plexin-B1, Critically Modulates Neuronal Migration and Patterning of the Developing Nervous System in Vivo The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2007 | Pubmed ID: 17554007 Cannabinoids Ameliorate Pain and Reduce Disease Pathology in Cerulein-induced Acute Pancreatitis Gastroenterology. May, 2007 | Pubmed ID: 17484889 A Molecular Basis of Analgesic Tolerance to Cannabinoids The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2007 | Pubmed ID: 17428994 Cyclin-dependent Kinase 5 Modulates Nociceptive Signaling Through Direct Phosphorylation of Transient Receptor Potential Vanilloid 1 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17194758 Synaptic Scaffolding Protein Homer1a Protects Against Chronic Inflammatory Pain Nature Medicine. Jun, 2006 | Pubmed ID: 16715092 Regulation of Motor Performance and Striatal Function by Synaptic Scaffolding Proteins of the Homer1 Family Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16407107 Mechanisms of Disease: Motoneuron Disease Aggravated by Transgenic Expression of a Functionally Modified AMPA Receptor Subunit Annals of the New York Academy of Sciences. Aug, 2005 | Pubmed ID: 16179532 Late-onset Motoneuron Disease Caused by a Functionally Modified AMPA Receptor Subunit Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15827116 Nitric Oxide Synthase (NOS)-interacting Protein Interacts with Neuronal NOS and Regulates Its Distribution and Activity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2004 | Pubmed ID: 15548660 The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain Neuron. Nov, 2004 | Pubmed ID: 15541312 Plexin-B1/RhoGEF-mediated RhoA Activation Involves the Receptor Tyrosine Kinase ErbB-2 The Journal of Cell Biology. Jun, 2004 | Pubmed ID: 15210733 Plexin-B Family Members Demonstrate Non-redundant Expression Patterns in the Developing Mouse Nervous System: an Anatomical Basis for Morphogenetic Effects of Sema4D During Development The European Journal of Neuroscience. May, 2004 | Pubmed ID: 15147296 Conditional Gene Deletion in Primary Nociceptive Neurons of Trigeminal Ganglia and Dorsal Root Ganglia Genesis (New York, N.Y. : 2000). Mar, 2004 | Pubmed ID: 15048809 Identification of Regulated Genes During Permanent Focal Cerebral Ischaemia: Characterization of the Protein Kinase 9b5/MARKL1/MARK4 Journal of Neurochemistry. Mar, 2004 | Pubmed ID: 15009667 TorsinA, the Gene Linked to Early-onset Dystonia, is Upregulated by the Dopaminergic Toxin MPTP in Mice Neuroscience Letters. Jan, 2004 | Pubmed ID: 14729251 TorsinA Protects Against Oxidative Stress in COS-1 and PC12 Cells Neuroscience Letters. Oct, 2003 | Pubmed ID: 14550917 Spinal Upregulation of the Nitric Oxide Synthase-interacting Protein NOSIP in a Rat Model of Inflammatory Pain Neuroscience Letters. Oct, 2003 | Pubmed ID: 12962906 Plexin-B1 Directly Interacts with PDZ-RhoGEF/LARG to Regulate RhoA and Growth Cone Morphology Neuron. Jul, 2002 | Pubmed ID: 12123608 Importance of the Gamma-aminobutyric Acid(B) Receptor C-termini for G-protein Coupling Molecular Pharmacology. May, 2002 | Pubmed ID: 11961124 In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice Christian Njoo1, Celine Heinl1, Rohini Kuner1 1Institute for Pharmacology, University of Heidelberg JoVE 51229 생물학
In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice Christian Njoo1, Celine Heinl1, Rohini Kuner1 1Institute for Pharmacology, University of Heidelberg JoVE 51229 생물학