Roland Tisch Department of Microbiology and Immunology University of North Carolina at Chapel Hill Biography Publications Institution JoVE Articles Roland Tisch has not added a biography. If you are Roland Tisch and would like to personalize this page please email our Author Liaison for assistance. Publications Reestablishing T Cell Tolerance by Antibody-Based Therapy in Type 1 Diabetes Archivum Immunologiae Et Therapiae Experimentalis. Mar, 2015 | Pubmed ID: 25790749 IL-2 Protects Lupus-prone Mice from Multiple End-organ Damage by Limiting CD4-CD8- IL-17-producing T Cells Journal of Immunology (Baltimore, Md. : 1950). Sep, 2014 | Pubmed ID: 25063876 Cutting Edge: Antigen-specific Thymocyte Feedback Regulates Homeostatic Thymic Conventional Dendritic Cell Maturation Journal of Immunology (Baltimore, Md. : 1950). Jul, 2014 | Pubmed ID: 24890722 Thymic Development of Autoreactive T Cells in NOD Mice is Regulated in an Age-dependent Manner Journal of Immunology (Baltimore, Md. : 1950). Dec, 2013 | Pubmed ID: 24198282 β-cell-specific IL-2 Therapy Increases Islet Foxp3+Treg and Suppresses Type 1 Diabetes in NOD Mice Diabetes. Nov, 2013 | Pubmed ID: 23884888 Manipulating T Cell-mediated Pathology: Targets and Functions of Monoclonal Antibody Immunotherapy Clinical Immunology (Orlando, Fla.). Jul, 2013 | Pubmed ID: 23688653 Kinetics of Adeno-associated Virus Serotype 2 (AAV2) and AAV8 Capsid Antigen Presentation in Vivo Are Identical Human Gene Therapy. May, 2013 | Pubmed ID: 23534873 Autoreactive Effector/memory CD4+ and CD8+ T Cells Infiltrating Grafted and Endogenous Islets in Diabetic NOD Mice Exhibit Similar T Cell Receptor Usage PloS One. 2012 | Pubmed ID: 23251685 IFN-γ Receptor Deficiency Prevents Diabetes Induction by Diabetogenic CD4+, but Not CD8+, T Cells European Journal of Immunology. Aug, 2012 | Pubmed ID: 22865049 Long-term Remission of Diabetes in NOD Mice is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies Diabetes. Nov, 2012 | Pubmed ID: 22751694 Cumulative Autoimmunity: T Cell Clones Recognizing Several Self-epitopes Exhibit Enhanced Pathogenicity Frontiers in Immunology. 2011 | Pubmed ID: 22566837 Reduced IL-2 Expression in NOD Mice Leads to a Temporal Increase in CD62Llo FoxP3+ CD4+ T Cells with Limited Suppressor Activity European Journal of Immunology. May, 2011 | Pubmed ID: 21469091 Inducible Adeno-associated Virus-mediated IL-2 Gene Therapy Prevents Autoimmune Diabetes Journal of Immunology (Baltimore, Md. : 1950). Mar, 2011 | Pubmed ID: 21317396 Genetic Vaccination for Re-establishing T-cell Tolerance in Type 1 Diabetes Human Vaccines. Jan, 2011 | Pubmed ID: 21157183 Dysregulation of Thymic Clonal Deletion and the Escape of Autoreactive T Cells Archivum Immunologiae Et Therapiae Experimentalis. Dec, 2010 | Pubmed ID: 20872284 Adiponectin Lowers Glucose Production by Increasing SOGA The American Journal of Pathology. Oct, 2010 | Pubmed ID: 20813965 Immunogenic Versus Tolerogenic Dendritic Cells: a Matter of Maturation International Reviews of Immunology. Apr, 2010 | Pubmed ID: 20367138 Central Nervous System Destruction Mediated by Glutamic Acid Decarboxylase-specific CD4+ T Cells Journal of Immunology (Baltimore, Md. : 1950). May, 2010 | Pubmed ID: 20348424 Toxin-coupled MHC Class I Tetramers Can Specifically Ablate Autoreactive CD8+ T Cells and Delay Diabetes in Nonobese Diabetic Mice Journal of Immunology (Baltimore, Md. : 1950). Apr, 2010 | Pubmed ID: 20220085 Beta Cell-specific CD4+ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19917704 Islet Lymphocyte Subsets in Male and Female NOD Mice Are Qualitatively Similar but Quantitatively Distinct Autoimmunity. 2009 | Pubmed ID: 19886740 Suppression of Ongoing T Cell-mediated Autoimmunity by Peptide-MHC Class II Dimer Vaccination Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19752238 A Novel Role for C-Src and STAT3 in Apoptotic Cell-mediated MerTK-dependent Immunoregulation of Dendritic Cells Blood. Oct, 2009 | Pubmed ID: 19667404 CD8(+) T Cells Specific for Beta Cells Encounter Their Cognate Antigens in the Islets of NOD Mice European Journal of Immunology. Oct, 2009 | Pubmed ID: 19658094 Cellular Immune Response to Cryptic Epitopes During Therapeutic Gene Transfer Proceedings of the National Academy of Sciences of the United States of America. Jun, 2009 | Pubmed ID: 19541644 Cytotoxic-T-lymphocyte-mediated Elimination of Target Cells Transduced with Engineered Adeno-associated Virus Type 2 Vector in Vivo Journal of Virology. Jul, 2009 | Pubmed ID: 19369348 MerTK Regulates Thymic Selection of Autoreactive T Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19251650 Role of Plasmacytoid Dendritic Cells in Type 1 Diabetes: Friend or Foe? Diabetes. Jan, 2009 | Pubmed ID: 19114722 Parameters Influencing Antigen-specific Immunotherapy for Type 1 Diabetes Immunologic Research. 2008 | Pubmed ID: 19052699 Immunotherapy of Type 1 Diabetes Archivum Immunologiae Et Therapiae Experimentalis. Jul-Aug, 2008 | Pubmed ID: 18726144 Gene Gun-mediated DNA Vaccination Enhances Antigen-specific Immunotherapy at a Late Preclinical Stage of Type 1 Diabetes in Nonobese Diabetic Mice Clinical Immunology (Orlando, Fla.). Oct, 2008 | Pubmed ID: 18675592 ANCA Patients Have T Cells Responsive to Complementary PR-3 Antigen Kidney International. Nov, 2008 | Pubmed ID: 18596726 Parameters Influencing Antigen-specific Immunotherapy for Type 1 Diabetes Immunologic Research. 2008 | Pubmed ID: 18543112 T-cell Promiscuity in Autoimmune Diabetes Diabetes. Aug, 2008 | Pubmed ID: 18492786 On the Pathogenicity of Autoantigen-specific T-cell Receptors Diabetes. May, 2008 | Pubmed ID: 18299317 B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice Despite Isotype-specific Differences in Fc Gamma R Effector Functions Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18292508 MerTK is Required for Apoptotic Cell-induced T Cell Tolerance The Journal of Experimental Medicine. Jan, 2008 | Pubmed ID: 18195070 Therapeutic B Cell Depletion Impairs Adaptive and Autoreactive CD4+ T Cell Activation in Mice Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18093919 Alphaviral Vector-transduced Dendritic Cells Are Successful Therapeutic Vaccines Against Neu-overexpressing Tumors in Wild-type Mice Vaccine. Sep, 2007 | Pubmed ID: 17675184 The Type and Frequency of Immunoregulatory CD4+ T-cells Govern the Efficacy of Antigen-specific Immunotherapy in Nonobese Diabetic Mice Diabetes. May, 2007 | Pubmed ID: 17317763 Identical Beta Cell-specific CD8(+) T Cell Clonotypes Typically Reside in Both Peripheral Blood Lymphocyte and Pancreatic Islets Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007 | Pubmed ID: 17237386 Apoptotic Cells Induce Mer Tyrosine Kinase-dependent Blockade of NF-kappaB Activation in Dendritic Cells Blood. Jan, 2007 | Pubmed ID: 17008547 EBV Latent Membrane Protein 2A Induces Autoreactive B Cell Activation and TLR Hypersensitivity Journal of Immunology (Baltimore, Md. : 1950). Sep, 2006 | Pubmed ID: 16920914 Lymphopenia-driven CD8(+) T Cells Are Resistant to Antigen-induced Tolerance in NOD.scid Mice European Journal of Immunology. Aug, 2006 | Pubmed ID: 16821236 Early Autoimmune Destruction of Islet Grafts is Associated with a Restricted Repertoire of IGRP-specific CD8+ T Cells in Diabetic Nonobese Diabetic Mice Journal of Immunology (Baltimore, Md. : 1950). Feb, 2006 | Pubmed ID: 16424193 Low-avidity CD8lo T Cells Induced by Incomplete Antigen Stimulation in Vivo Regulate Naive Higher Avidity CD8hi T Cell Responses to the Same Antigen European Journal of Immunology. Feb, 2006 | Pubmed ID: 16402405 Immunotherapy for the Prevention and Treatment of Type 1 Diabetes International Reviews of Immunology. Sep-Dec, 2005 | Pubmed ID: 16318984 Immunoregulation of Dendritic Cells Clinical Medicine & Research. Aug, 2005 | Pubmed ID: 16160071 Single Cell Analysis Shows Decreasing FoxP3 and TGFbeta1 Coexpressing CD4+CD25+ Regulatory T Cells During Autoimmune Diabetes The Journal of Experimental Medicine. Apr, 2005 | Pubmed ID: 15837817 Immunoregulation of Dendritic Cells by IL-10 is Mediated Through Suppression of the PI3K/Akt Pathway and of IkappaB Kinase Activity Blood. Aug, 2004 | Pubmed ID: 15113757 Critical Roles of Tumor Necrosis Factor-related Apoptosis-inducing Ligand in Type 1 Diabetes Diabetes. Sep, 2003 | Pubmed ID: 12941766 More Stringent Conditions of Plasmid DNA Vaccination Are Required to Protect Grafted Versus Endogenous Islets in Nonobese Diabetic Mice Journal of Immunology (Baltimore, Md. : 1950). Jul, 2003 | Pubmed ID: 12817032 NF-kappa B Hyperactivation Has Differential Effects on the APC Function of Nonobese Diabetic Mouse Macrophages Journal of Immunology (Baltimore, Md. : 1950). Feb, 2003 | Pubmed ID: 12574341 The Preferential Ability of B Lymphocytes to Act As Diabetogenic APC in NOD Mice Depends on Expression of Self-antigen-specific Immunoglobulin Receptors European Journal of Immunology. Dec, 2002 | Pubmed ID: 12516557 L-selectin is Not Required for T Cell-mediated Autoimmune Diabetes Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002 | Pubmed ID: 11884430 Elevated NF-kappaB Activation in Nonobese Diabetic Mouse Dendritic Cells Results in Enhanced APC Function Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11751962 العزل وزرع مختلفة المسنين الفئران التوتة الطعوم. Y. Maurice Morillon II*1, Fatima Manzoor*1, Bo Wang1, Roland Tisch1 1Department of Microbiology and Immunology, University of North Carolina at Chapel Hill 면역학 및 감염병학
العزل وزرع مختلفة المسنين الفئران التوتة الطعوم. Y. Maurice Morillon II*1, Fatima Manzoor*1, Bo Wang1, Roland Tisch1 1Department of Microbiology and Immunology, University of North Carolina at Chapel Hill 면역학 및 감염병학