Shaun W. Lee

Publications

• Novel Genomic Rearrangements Mediated by Multiple Genetic Elements in Streptococcus Pyogenes M23ND Confer Potentials for Evolutionary Persistence
  Microbiology (Reading, England). Jun, 2016  |   Pubmed ID: 27329479
• Genomic Characterization of a Pattern D Streptococcus Pyogenes Emm53 Isolate Reveals a Genetic Rationale for Invasive Skin Tropicity
  Journal of Bacteriology. Jun, 2016  |   Pubmed ID: 27044623
• Streptococcus Pyogenes Employs Strain-dependent Mechanisms of C3b Inactivation to Inhibit Phagocytosis and Killing of Bacteria
  The Journal of Biological Chemistry. Apr, 2016  |   Pubmed ID: 26945067
• A Large Scale Prediction of Bacteriocin Gene Blocks Suggests a Wide Functional Spectrum for Bacteriocins
  BMC Bioinformatics. 2015  |   Pubmed ID: 26558535
• Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes During Group A Streptococcus Infection
  Infection and Immunity. Oct, 2015  |   Pubmed ID: 26238711
• CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus Pyogenes Provides New Insights into Virulence Determinants
  Journal of Bacteriology. Oct, 2015  |   Pubmed ID: 26216843
• Design and Evaluation of a Peptide-based Immunotoxin for Breast Cancer Therapeutics
  FEBS Open Bio. 2015  |   Pubmed ID: 25853036
• A Multiparametric Computational Algorithm for Comprehensive Assessment of Genetic Mutations in Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome)
  PloS One. 2015  |   Pubmed ID: 25807448
• HIV Protease Inhibitors Block Streptolysin S Production
  ACS Chemical Biology. May, 2015  |   Pubmed ID: 25668590
• Unique Genomic Arrangements in an Invasive Serotype M23 Strain of Streptococcus Pyogenes Identify Genes That Induce Hypervirulence
  Journal of Bacteriology. Dec, 2014  |   Pubmed ID: 25225265
• The Wide World of Ribosomally Encoded Bacterial Peptides
  PLoS Pathogens. Jul, 2014  |   Pubmed ID: 25079075
• Mutations in the Control of Virulence Sensor Gene from Streptococcus Pyogenes After Infection in Mice Lead to Clonal Bacterial Variants with Altered Gene Regulatory Activity and Virulence
  PloS One. 2014  |   Pubmed ID: 24968349
• Knowing is Half the Battle: Targeting Virulence Factors of Group A Streptococcus for Vaccine and Therapeutics
  Current Drug Targets. Mar, 2012  |   Pubmed ID: 22206254
• An Escherichia Coli-based Bioengineering Strategy to Study Streptolysin S Biosynthesis
  Analytical Biochemistry. Jan, 2012  |   Pubmed ID: 22001374
• Clostridiolysin S, a Post-translationally Modified Biotoxin from Clostridium Botulinum
  The Journal of Biological Chemistry. Sep, 2010  |   Pubmed ID: 20581111
• Structural and Functional Dissection of the Heterocyclic Peptide Cytotoxin Streptolysin S
  The Journal of Biological Chemistry. May, 2009  |   Pubmed ID: 19286651
• Discovery of a Widely Distributed Toxin Biosynthetic Gene Cluster
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008  |   Pubmed ID: 18375757
• Dynamics of Neisseria Gonorrhoeae Attachment: Microcolony Development, Cortical Plaque Formation, and Cytoprotection
  Infection and Immunity. Oct, 2007  |   Pubmed ID: 17682045
• Monoclonal Antibody Detection of CD46 Clustering Beneath Neisseria Gonorrhoeae Microcolonies
  Infection and Immunity. Apr, 2006  |   Pubmed ID: 16552073
• PilT is Required for PI(3,4,5)P3-mediated Crosstalk Between Neisseria Gonorrhoeae and Epithelial Cells
  Cellular Microbiology. Sep, 2005  |   Pubmed ID: 16098215
• CD46 is Phosphorylated at Tyrosine 354 Upon Infection of Epithelial Cells by Neisseria Gonorrhoeae
  The Journal of Cell Biology. Mar, 2002  |   Pubmed ID: 11901164