Shigeo Okabe Department of Cellular Neurobiology, Graduate School of Medicine and Faculty of Medicine The University of Tokyo Biography Publications Institution JoVE Articles Shigeo Okabe has not added a biography. If you are Shigeo Okabe and would like to personalize this page please email our Author Liaison for assistance. Publications The 70th Anniversary Issue: Preface Microscopy (Oxford, England). 02, 2022 | Pubmed ID: 35275184 Imaging Neural Circuit Pathology of Autism Spectrum Disorders: Autism-associated Genes, Animal Models and the Application of in Vivo Two-photon Imaging Microscopy (Oxford, England). Feb, 2022 | Pubmed ID: 35275183 Advanced Technologies for Local Neural Circuits in the Cerebral Cortex Frontiers in Neuroanatomy. 2021 | Pubmed ID: 34803616 Neuroscience20 (BRAIN20, SPINE20, and MENTAL20) Health Initiative: A Global Consortium Addressing the Human and Economic Burden of Brain, Spine, and Mental Disorders Through Neurotech Innovations and Policies Journal of Alzheimer's Disease : JAD. 2021 | Pubmed ID: 34487051 Genetic Dissection Identifies Necdin As a Driver Gene in a Mouse Model of Paternal 15q Duplications Nature Communications. 07, 2021 | Pubmed ID: 34210967 Canonical Versus Non-canonical Transsynaptic Signaling of Neuroligin 3 Tunes Development of Sociality in Mice Nature Communications. 03, 2021 | Pubmed ID: 33758193 The Role of Molecular Diffusion Within Dendritic Spines in Synaptic Function The Journal of General Physiology. 04, 2021 | Pubmed ID: 33720306 Imaging of Spine Synapses Using Super-resolution Microscopy Anatomical Science International. Jun, 2021 | Pubmed ID: 33459976 Geometry and the Organizational Principle of Spine Synapses Along a Dendrite ENeuro. Nov-Dec, 2020 | Pubmed ID: 33109633 Regulation of Actin Dynamics in Dendritic Spines: Nanostructure, Molecular Mobility, and Signaling Mechanisms Molecular and Cellular Neurosciences. 12, 2020 | Pubmed ID: 33096206 Recent Advances in Computational Methods for Measurement of Dendritic Spines Imaged by Light Microscopy Microscopy (Oxford, England). Jul, 2020 | Pubmed ID: 32244257 Vasodilator-stimulated Phosphoprotein (VASP) is Recruited into Dendritic Spines Via G-actin-dependent Mechanism and Contributes to Spine Enlargement and Stabilization The European Journal of Neuroscience. 02, 2020 | Pubmed ID: 31793065 Neonatal Social Isolation Increases the Proportion of the Immature Spines in the Layer 2/3 Pyramidal Neurons of the Somatosensory Cortex Neuroscience Research. May, 2020 | Pubmed ID: 31226269 Temporal Sequences of Synapse Disintegration Triggered by Afferent Axon Transection, Time-Lapse Imaging Study of Presynaptic and Postsynaptic Molecules ENeuro. Sep/Oct, 2019 | Pubmed ID: 31515235 Precise Temporal Regulation of Molecular Diffusion Within Dendritic Spines by Actin Polymers During Structural Plasticity Cell Reports. 04, 2019 | Pubmed ID: 31042476 Computational Geometry Analysis of Dendritic Spines by Structured Illumination Microscopy Nature Communications. 03, 2019 | Pubmed ID: 30894537 LAMP5 in Presynaptic Inhibitory Terminals in the Hindbrain and Spinal Cord: a Role in Startle Response and Auditory Processing Molecular Brain. 03, 2019 | Pubmed ID: 30867010 Neuroethical Issues of the Brain/MINDS Project of Japan Neuron. 02, 2019 | Pubmed ID: 30731063 Ultrastructural Observation of Glutamatergic Synapses by Focused Ion Beam Scanning Electron Microscopy (FIB/SEM) Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30707424 Cellular Cartography of the Organ of Corti Based on Optical Tissue Clearing and Machine Learning ELife. 01, 2019 | Pubmed ID: 30657453 Spatial Impact of Microglial Distribution on Dynamics of Dendritic Spines The European Journal of Neuroscience. 06, 2019 | Pubmed ID: 30585660 Red-Shifted Fluorogenic Substrate for Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution Angewandte Chemie (International Ed. in English). 11, 2018 | Pubmed ID: 30255610 Near-infrared Deep Brain Stimulation Via Upconversion Nanoparticle-mediated Optogenetics Science (New York, N.Y.). 02, 2018 | Pubmed ID: 29439241 Synapse Elimination Triggered by BMP4 Exocytosis and Presynaptic BMP Receptor Activation Cell Reports. 01, 2018 | Pubmed ID: 29386134 Developmental Stage-dependent Regulation of Spine Formation by Calcium-calmodulin-dependent Protein Kinase IIα and Rap1 Scientific Reports. 10, 2017 | Pubmed ID: 29042611 Fluorescence Imaging of Synapse Dynamics in Normal Circuit Maturation and in Developmental Disorders Proceedings of the Japan Academy. Series B, Physical and Biological Sciences. 2017 | Pubmed ID: 28769018 Quantification of Sympathetic Hyperinnervation and Denervation After Myocardial Infarction by Three-dimensional Assessment of the Cardiac Sympathetic Network in Cleared Transparent Murine Hearts PloS One. 2017 | Pubmed ID: 28753665 AMPA Glutamate Receptors Are Required for Sensory-organ Formation and Morphogenesis in the Basal Chordate Proceedings of the National Academy of Sciences of the United States of America. 04, 2017 | Pubmed ID: 28348228 Insights into Age-old Questions of New Dendritic Spines: From Form to Function Brain Research Bulletin. 03, 2017 | Pubmed ID: 27491624 Fast 3D Visualization of Endogenous Brain Signals with High-sensitivity Laser Scanning Photothermal Microscopy Biomedical Optics Express. May, 2016 | Pubmed ID: 27231615 Temporal Changes in the Response of SVZ Neural Stem Cells to Intraventricular Administration of Growth Factors Brain Research. Apr, 2016 | Pubmed ID: 26845459 High Affinity Receptor Labeling Based on Basic Leucine Zipper Domain Peptides Conjugated with PH-sensitive Fluorescent Dye: Visualization of AMPA-type Glutamate Receptor Endocytosis in Living Neurons Neuropharmacology. Jan, 2016 | Pubmed ID: 26220312 For Microscopy Special Feature on 'super Resolution Microscopy' Microscopy (Oxford, England). Aug, 2015 | Pubmed ID: 26169203 Brain/MINDS - a New Program for Comprehensive Analyses of the Brain Microscopy (Oxford, England). Feb, 2015 | Pubmed ID: 25652425 For Microscopy Special Issue on 'connectome' Microscopy (Oxford, England). Feb, 2015 | Pubmed ID: 25652424 Neuroprotection by JM-1232(-) Against Oxygen-glucose Deprivation-induced Injury in Rat Hippocampal Slice Culture Brain Research. Jan, 2015 | Pubmed ID: 25451121 Up-regulation of HP1γ Expression During Neuronal Maturation Promotes Axonal and Dendritic Development in Mouse Embryonic Neocortex Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Feb, 2015 | Pubmed ID: 25441120 Enhanced Synapse Remodelling As a Common Phenotype in Mouse Models of Autism Nature Communications. Aug, 2014 | Pubmed ID: 25144834 Structural Dynamics of Dendritic Spines: Molecular Composition, Geometry and Functional Regulation Biochimica Et Biophysica Acta. Oct, 2014 | Pubmed ID: 24915021 Life Science and Microscopy in 2014 Microscopy (Oxford, England). Feb, 2014 | Pubmed ID: 24520136 Dlx1 Transcription Factor Regulates Dendritic Growth and Postsynaptic Differentiation Through Inhibition of Neuropilin-2 and PAK3 Expression The European Journal of Neuroscience. Feb, 2014 | Pubmed ID: 24236816 Evaluation of Cranial Window Types for in Vivo Two-photon Imaging of Brain Microstructures Microscopy (Oxford, England). Feb, 2014 | Pubmed ID: 24212360 Fluorescence Imaging of Synapse Formation and Remodeling Microscopy (Oxford, England). Feb, 2013 | Pubmed ID: 23243097 Molecular Dynamics of the Excitatory Synapse Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22351054 [Molecular Mechanism Underlying the Formation and Maintenance of Excitatory Synapses] Brain and Nerve = Shinkei Kenkyu No Shinpo. Jan, 2011 | Pubmed ID: 21228448 [Dynamics of Neurons: Integrated Approaches from Molecules, Cells to Model Animals] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Feb, 2009 | Pubmed ID: 19205353 Regeneration of Hippocampal Pyramidal Neurons After Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors Cell. Aug, 2002 | Pubmed ID: 12202033 Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice Hisato Maruoka1, Ryosuke Kamei1, Shunsuke Mizutani1, Qingrui Liu1, Shigeo Okabe1 1Department of Cellular Neurobiology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo JoVE 64111 신경과학 In Vivo Chronic Two-Photon Imaging of Microglia in the Mouse Hippocampus Ryosuke Kamei1, Shinji Urata1, Hisato Maruoka1, Shigeo Okabe1 1Department of Cellular Neurobiology, Graduate School of Medicine, The University of Tokyo JoVE 64104 신경과학
Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice Hisato Maruoka1, Ryosuke Kamei1, Shunsuke Mizutani1, Qingrui Liu1, Shigeo Okabe1 1Department of Cellular Neurobiology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo JoVE 64111 신경과학
In Vivo Chronic Two-Photon Imaging of Microglia in the Mouse Hippocampus Ryosuke Kamei1, Shinji Urata1, Hisato Maruoka1, Shigeo Okabe1 1Department of Cellular Neurobiology, Graduate School of Medicine, The University of Tokyo JoVE 64104 신경과학