Sijie Chen Ming Wai Lau Centre for Reparative Medicine Karolinska Institutet Biography Publications Institution JoVE Articles Sijie Chen Sijie Chen obtained her PhD from Hong Kong University of Science and Technology in 2013. She received the Endeavour fellowship and worked as an Endeavour Fellow in University of Melbourne and a visiting scientist in Walter and Eliza Hall Institute of Medical Research (WEHI) in 2015. Thereafter, she joined Karolinksa Institutet (KI) in Sweden as a postdoctoral fellow. Dr. Chen was recruited as an Assistant Professor at Ming Wai Lau Centre for Reparative Medicine, KI, Hong Kong in 2017. Her current research interests focus on the development of new luminescent materials and techniques for biological research. Publications Imaging macrophage phagocytosis using AIE luminogen-labeled E. coli Chemistry - A Asian Journal. January,2019 | Pubmed ID: Fluorogenic detection and characterization of proteins by aggregation-induced emission methods Chemistry - A European Journal. January,2019 | Pubmed ID: Solution-controlled conformational switching of an Anchored wireframe DNA nanostructure Small. December,2018 | Pubmed ID: Fluorogenic Ag+-Tetrazolate Aggregation Enables Novel and Efficient Fluorescent Biological Silver Staining Angewandte Chemie International Edition. May,2018 | Pubmed ID: 29575702Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells Materials Horizons. July,2018 | Pubmed ID: AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications Molecules. February,2018 | Pubmed ID: 29443927Real-Time Imaging of Cell Behaviors in Living Organisms by a Mitochondria Targeting AIE Fluorogen Advanced Functional Materials. August,2016 | Pubmed ID: Fabrication of Fluorescent Nanoparticles Based on AIE Luminogens (AIE dots) and Their Applications in Bioimaging Materials Horizons. April,2016 | Pubmed ID: A red emittng mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity Chemical Communications. August,2015 | Pubmed ID: Mapping Live Cell Viscosity with an Aggregation-Induced Emission Fluorogen by Means of Two-Photon Fluorescence Lifetime Imaging Chemistry - A European Journal. February,2015 | Pubmed ID: Discrimination of homocysteine, cysteine and glutathione using an aggregation-induced-emission-active hemicyaninedye Journal of Materials Chemistry B. April,2014 | Pubmed ID: Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission-Active Two-Channel Ratiometric Fluorogen Journal of the American Chemical Society. March,2013 | Pubmed ID: Long-Term Fluorescent Cellular Tracing by the aggregates of AIE Bioconjugates Journal of the American Chemical Society. May,2013 | Pubmed ID: An AIEactive hemicyanine fluorogen with stimuli-responsive red/blue emission: extending the pH sensing range by "switch + knob" effect Chemical Science. March,2012 | Pubmed ID: Novel super-resolution capable mitochondrial probe, MitoRed AIE, enables assessment of real-time molecular mitochondrial dynamics Scientific Report. August,2016 | Pubmed ID: A Lysosome-Targeting AIEgen for Autophagy Visualization Advanced Healthcare Materials. February,2016 | Pubmed ID: 26688031ALuminogen with Aggregation-Induced Emission Characteristics for Wash-Free Bacterial Imaging, High-Throughput Antibiotics Screening and Bacterial Susceptibility Evaluation Advanced Materials. September,2015 | Pubmed ID: Light-Enhanced Bacterial Killing and Wash-Free Imaging Based on AIE Fluorogen ACS Applied Ma??erials& Interfaces. March,2015 | Pubmed ID: Real-time monitoring of the mitophagy process by a photostable fluorescent mitochondrion-specific bioprobe with AIE characteristics Chemical Communications. April,2015 | Pubmed ID: Photostable AIEfluorogens for accurate and sensitive detection of Sphase DNA synthesis and cell proliferation Journal of Materials Chemistry B. April,2015 | Pubmed ID: Detection of oligomers and fibrils of alpha-synuclein byAIEgen with strong fluorescence Chemical Communications. December,2014 | Pubmed ID: A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy Chemical Communications. September,2014 | Pubmed ID: Synthesis, Properties, and Applications of Poly(ethylene glycol)-Decorated Tetraphenylethenes Journal of Materials Chemistry. C. June,2014 | Pubmed ID: A Tetraphenylethene-based caged compound: synthesis, properties and applicationsChemical Communications. August,2014 | Pubmed ID: 24923580Highly Fluorescent and Photostable Probe for Long-Term Bacterial Viability Assay Based on Aggregation-Induced Emission Advanced Healthcare Materials. January,2014 | Pubmed ID: 23814037A Selective Glutathione Probe based on AIE Fluorogen and its Application in Enzymatic Activity Assay Scientific Reports. March,2014 | Pubmed ID: 24603274Superior Fluorescent Probe for Detection of Cardiolipin Analytical Chemistry. January,2014 | Pubmed ID: 24372165Detection of adenine-rich ssDNA based on thyminesubstituted tetraphenylethene with aggregation-induced emission characteristics RSC Advances. July,2014 | Pubmed ID: A Photostable AIELuminogen for Specific Mitochondrial Imaging and Tracking Journal of the American Chemical Society. December,2012 | Pubmed ID: Water-Soluble TetraphenyletheneDerivatives as Fluorescent 'Light-Up' Probes for Nucleic Acid Detection and Their Applications in Cell Imaging Chemistry - An Asian Journal. August,2013 | Pubmed ID: 23596133Ordered Honeycomb Structural Interfaces for Anticancer Cells Growth Langmuir. November,2013 | Pubmed ID: Thiol-Reactive Molecule with Dual-Emission-Enhancement Property for Specific Prestaining of Cysteine Containing Proteins in SDS-PAGE ACS Appl. Mater. Interfaces. May,2013 | Pubmed ID: Defect-sensitive crystals based on diaminomaleonitrile-functionalized Schiff base with aggregation-enhanced emission Journal of Materials Chemistry C. September,2013 | Pubmed ID: Fabrication of Chitosan Nanoparticles with Aggregation-Induced Emission Characteristics and Their Applications in Long-term Live Cell Imaging Macromolecular Rapid Communications. May,2013 | Pubmed ID: Biotin-decorated Fluorescent Silica Nanoparticles with Aggregation-Induced Emission Characteristics: Fabrication, Cytotoxicity and Biological Applications Journal of Materials Chemistry. B. November,2012 | Pubmed ID: Fluorescent pH sensor constructed from a heteroatomcontaining luminogen with tunable AIE and ICT characteristics Chemical Science. July,2013 | Pubmed ID: Patterned Honeycomb Structural Films with Fluorescent and Hydrophobic Properties Journal of Nanomaterials. September,2013 | Pubmed ID: Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogenwith Aggregation-Induced Emission Characteristics Journal of the American Chemical Society. December,2011 | Pubmed ID: Fabrication of small organic luminogens honeycomb-structured films with aggregation-induced emission features Journal of Materials Chemistry. June,2012 | Pubmed ID: Aggregation-induced red-NIR emission organic nanoparticles as effective and photostable fluorescent probes for bioimaging Journal of Materials Chemistry. May,2012 | Pubmed ID: Tetraphenylethenyl-modified perylene bisimide: aggregation-induced red emission, electrochemical properties and ordered microstructures Journal of Materials Chemistry. March,2012 | Pubmed ID: Benzothiazoliumfunctionalized tetraphenylethene: an AIE luminogen withtunable solid-state emission Chemical Communications. July,2012 | Pubmed ID: Synthesis, solvatochromism, aggregation-induced emission and cell imaging of tetraphenylethene-containing BODIPY derivatives with large Stokes shifts Chemical Communications. August,2012 | Pubmed ID: Cytophilic Fluorescent Bioprobes for Long-Term Cell Tracking Advanced Materials. August,2011 | Pubmed ID: 21671445Fluorogenic Zn(II) and Chromogenic Fe(II) Sensors Based on Terpyridine-SubstitutedTetraphenylethenes with Aggregation-Induced Emission Characteristics Applied Materials and Interfaces. September,2011 | Pubmed ID: 21834577Aggregation-Induced Emission and Biological Application of Tetraphenylethene Luminogens Australian Journal of Chemistry. July,2011 | Pubmed ID: Floresan gümüş Polyacrylamide jeller proteinlerin boyama Alex Y. H. Wong1, Sheng Xie1, Ben Zhong Tang2, Sijie Chen1 1Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, 2Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, State Key Laboratory of Neuroscience, Division of Biomedical Engineering, and Division of Life Science, Hong Kong University of Science and Technology JoVE 58669 생화학 Larva Zebra balığı Gonadal Doku Diseksiyon Xinjian Wang*1, Sijie Chen*1, Wei Zhang1, Yiyuan Ren1, Quan Zhang1, Gang Peng1 1Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science, Fudan University JoVE 55294 발생학
Floresan gümüş Polyacrylamide jeller proteinlerin boyama Alex Y. H. Wong1, Sheng Xie1, Ben Zhong Tang2, Sijie Chen1 1Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, 2Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, State Key Laboratory of Neuroscience, Division of Biomedical Engineering, and Division of Life Science, Hong Kong University of Science and Technology JoVE 58669 생화학
Larva Zebra balığı Gonadal Doku Diseksiyon Xinjian Wang*1, Sijie Chen*1, Wei Zhang1, Yiyuan Ren1, Quan Zhang1, Gang Peng1 1Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science, Fudan University JoVE 55294 발생학