Steven Goossens Department of Biomedical Molecular Biology Ghent University Biography Publications Institution JoVE Articles Steven Goossens has not added a biography. If you are Steven Goossens and would like to personalize this page please email our Author Liaison for assistance. Publications Oncogenic ZEB2 Activation Drives Sensitivity Toward KDM1A Inhibition in T-cell Acute Lymphoblastic Leukemia Blood. Feb, 2017 | Pubmed ID: 28069602 Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2017 | Pubmed ID: 27739137 The EMT Transcription Factor Zeb2 Controls Adult Murine Hematopoietic Differentiation by Regulating Cytokine Signaling Blood. Jan, 2017 | Pubmed ID: 27683414 Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia PLoS Medicine. Dec, 2016 | Pubmed ID: 27997538 Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations Using the Rosa26 Locus Journal of Neuromuscular Diseases. May, 2016 | Pubmed ID: 27854215 P120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification PLoS Genetics. Aug, 2016 | Pubmed ID: 27556156 LIN28B is Over-expressed in Specific Subtypes of Pediatric Leukemia and Regulates LncRNA H19 Haematologica. Jun, 2016 | Pubmed ID: 26969084 Transcriptional Repressor ZEB2 Promotes Terminal Differentiation of CD8+ Effector and Memory T Cell Populations During Infection The Journal of Experimental Medicine. Nov, 2015 | Pubmed ID: 26503445 Terminal NK Cell Maturation is Controlled by Concerted Actions of T-bet and Zeb2 and is Essential for Melanoma Rejection The Journal of Experimental Medicine. Nov, 2015 | Pubmed ID: 26503444 Novel Biological Insights in T-cell Acute Lymphoblastic Leukemia Experimental Hematology. Aug, 2015 | Pubmed ID: 26123366 Strategies to Rescue the Consequences of Inducible Arginase-1 Deficiency in Mice PloS One. 2015 | Pubmed ID: 25938595 ZEB2 Drives Immature T-cell Lymphoblastic Leukaemia Development Via Enhanced Tumour-initiating Potential and IL-7 Receptor Signalling Nature Communications. Jan, 2015 | Pubmed ID: 25565005 Alpha-catenins Control Cardiomyocyte Proliferation by Regulating Yap Activity Circulation Research. Jan, 2015 | Pubmed ID: 25305307 Controlling Pre-leukemic Thymocyte Self-renewal PLoS Genetics. Dec, 2014 | Pubmed ID: 25522333 ABT-199 Mediated Inhibition of BCL-2 As a Novel Therapeutic Strategy in T-cell Acute Lymphoblastic Leukemia Blood. Dec, 2014 | Pubmed ID: 25301704 MicroRNA-128-3p is a Novel OncomiR Targeting PHF6 in T-cell Acute Lymphoblastic Leukemia Haematologica. Aug, 2014 | Pubmed ID: 24895337 Loss of Autocrine Endothelial-derived VEGF Significantly Reduces Hemangiosarcoma Development in Conditional P53-deficient Mice Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 24626176 ZEB2-transgene Expression in the Epidermis Compromises the Integrity of the Epidermal Barrier Through the Repression of Different Tight Junction Proteins Cellular and Molecular Life Sciences : CMLS. Sep, 2014 | Pubmed ID: 24573695 Efficient ROSA26-based Conditional And/or Inducible Transgenesis Using RMCE-compatible F1 Hybrid Mouse Embryonic Stem Cells Stem Cell Reviews. Dec, 2013 | Pubmed ID: 23877658 Beta-Actin Is Involved in Modulating Erythropoiesis During Development by Fine-Tuning Gata2 Expression Levels PloS One. 2013 | Pubmed ID: 23840778 The P53 Family and VEGF Regulation: "It's Complicated" Cell Cycle (Georgetown, Tex.). May, 2013 | Pubmed ID: 23588071 The ROSA26-iPSC Mouse: a Conditional, Inducible, and Exchangeable Resource for Studying Cellular (De)differentiation Cell Reports. Feb, 2013 | Pubmed ID: 23395636 Directed Migration of Cortical Interneurons Depends on the Cell-autonomous Action of Sip1 Neuron. Jan, 2013 | Pubmed ID: 23312517 Loss of αT-catenin Alters the Hybrid Adhering Junctions in the Heart and Leads to Dilated Cardiomyopathy and Ventricular Arrhythmia Following Acute Ischemia Journal of Cell Science. Feb, 2012 | Pubmed ID: 22421363 A Vascular Niche and a VEGF-Nrp1 Loop Regulate the Initiation and Stemness of Skin Tumours Nature. Oct, 2011 | Pubmed ID: 22012397 Catalytic Production of Conjugated Fatty Acids and Oils ChemSusChem. Jun, 2011 | Pubmed ID: 21634014 Design of Ru-zeolites for Hydrogen-free Production of Conjugated Linoleic Acids ChemSusChem. Jun, 2011 | Pubmed ID: 21506286 The EMT Regulator Zeb2/Sip1 is Essential for Murine Embryonic Hematopoietic Stem/progenitor Cell Differentiation and Mobilization Blood. May, 2011 | Pubmed ID: 21355089 Vegf Regulates Embryonic Erythroid Development Through Gata1 Modulation Blood. Sep, 2010 | Pubmed ID: 20554972 Increased Skeletal VEGF Enhances Beta-catenin Activity and Results in Excessively Ossified Bones The EMBO Journal. Jan, 2010 | Pubmed ID: 20010698 Efficient Mouse Transgenesis Using Gateway-compatible ROSA26 Locus Targeting Vectors and F1 Hybrid ES Cells Nucleic Acids Research. Apr, 2009 | Pubmed ID: 19279185 Plakophilin-3-deficient Mice Develop Hair Coat Abnormalities and Are Prone to Cutaneous Inflammation The Journal of Investigative Dermatology. Jun, 2008 | Pubmed ID: 18079750 A Unique and Specific Interaction Between AlphaT-catenin and Plakophilin-2 in the Area Composita, the Mixed-type Junctional Structure of Cardiac Intercalated Discs Journal of Cell Science. Jun, 2007 | Pubmed ID: 17535849 Alpha-T-catenin (CTNNA3) Displays Tumour Specific Monoallelic Expression in Urothelial Carcinoma of the Bladder Genes, Chromosomes & Cancer. Jun, 2007 | Pubmed ID: 17366617 Truncated Isoform of Mouse AlphaT-catenin is Testis-restricted in Expression and Function FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2007 | Pubmed ID: 17185752 Cadherin-mediated Cell-cell Adhesion in the Testis Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2005 | Pubmed ID: 15574378 GATA-4 and MEF2C Transcription Factors Control the Tissue-specific Expression of the AlphaT-catenin Gene CTNNA3 Nucleic Acids Research. 2004 | Pubmed ID: 15302915 Alpha-T-catenin is Expressed in Human Brain and Interacts with the Wnt Signaling Pathway but is Not Responsible for Linkage to Chromosome 10 in Alzheimer's Disease Neuromolecular Medicine. 2004 | Pubmed ID: 15075440 Assessment of the CTNNA3 Gene Encoding Human Alpha T-catenin Regarding Its Involvement in Dilated Cardiomyopathy Human Genetics. Mar, 2003 | Pubmed ID: 12596047 Struktur og funktion Studier i embryonale stamceller fra mus Brug rekombinase-medieret Cassette Exchange Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 발생학
Struktur og funktion Studier i embryonale stamceller fra mus Brug rekombinase-medieret Cassette Exchange Tim Pieters1,2,3,4, Lieven Haenebalcke1,2, Kenneth Bruneel1,2,4, Niels Vandamme1,2,4, Tino Hochepied1,2, Jolanda van Hengel5, Dagmar Wirth6, Geert Berx1,2,4, Jody J. Haigh7, Frans van Roy1,2,4, Steven Goossens1,2,3,4 1Department of Biomedical Molecular Biology, Ghent University, 2Inflammation Research Center, VIB, 3Center for Medical Genetics, Ghent University Hospital, 4Cancer Research Institute Ghent (CRIG), 5Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, 6Helmholtz Center for Infection Research, 7Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre JoVE 55575 발생학