Sven G. Meuth Department of Neurology, Medical Faculty Heinrich Heine University Duesseldorf Biography Publications Institution JoVE Articles Sven G. Meuth has not added a biography. If you are Sven G. Meuth and would like to personalize this page please email our Author Liaison for assistance. Publications Senescent Fibro-adipogenic Progenitors Are Potential Drivers of Pathology in Inclusion Body Myositis Acta Neuropathologica. Sep, 2023 | Pubmed ID: 37773216 Introducing Electronic Monitoring of Disease Activity in Patients with Chronic Inflammatory Demyelinating Polyneuropathy (EMDA CIDP): Trial Protocol of a Proof of Concept Study Neurological Research and Practice. Aug, 2023 | Pubmed ID: 37612774 Treatment of Autoimmunity: The Impact of Disease-modifying Therapies in Multiple Sclerosis and Comorbid Autoimmune Disorders Autoimmunity Reviews. May, 2023 | Pubmed ID: 36924922 Driving Time-based Identification of Gaps in Specialised Care Coverage: An Example of Neuroinflammatory Diseases in Germany Digital Health. 2023 | Pubmed ID: 36762020 Myositis in Germany: Epidemiological Insights over 15 years from 2005 to 2019 Neurological Research and Practice. Dec, 2022 | Pubmed ID: 36581896 Real-world Evidence on Siponimod Treatment in Patients with Secondary Progressive Multiple Sclerosis Neurological Research and Practice. Nov, 2022 | Pubmed ID: 36336685 Immunoadsorption Versus Double-dose Methylprednisolone in Refractory Multiple Sclerosis Relapses Journal of Neuroinflammation. Sep, 2022 | Pubmed ID: 36071461 Deficiency of the Two-Pore Potassium Channel KCNK9 Impairs Intestinal Epithelial Cell Survival and Aggravates Dextran Sodium Sulfate-Induced Colitis Cellular and Molecular Gastroenterology and Hepatology. 2022 | Pubmed ID: 35973573 Activation of Non-classical NMDA Receptors by Glycine Impairs Barrier Function of Brain Endothelial Cells Cellular and Molecular Life Sciences : CMLS. Aug, 2022 | Pubmed ID: 35951110 [Multiple Sclerosis: Interventions to Halt Disease : Which Patients Can Be Considered for Autologous Stem Cell Transplantation] Der Nervenarzt. Oct, 2022 | Pubmed ID: 35951049 Thinking Outside the Box: Non-canonical Targets in Multiple Sclerosis Nature Reviews. Drug Discovery. Aug, 2022 | Pubmed ID: 35668103 An Optimized and Validated Protocol for Inducing Chronic Experimental Autoimmune Encephalomyelitis in C57BL/6J Mice Journal of Neuroscience Methods. Feb, 2022 | Pubmed ID: 34920025 Mini-Review: Two Brothers in Crime - The Interplay of TRESK and TREK in Human Diseases Neuroscience Letters. Jan, 2022 | Pubmed ID: 34852287 Ocrelizumab Extended Interval Dosing in Multiple Sclerosis in Times of COVID-19 Neurology(R) Neuroimmunology & Neuroinflammation. Sep, 2021 | Pubmed ID: 34261812 Impact of Diverse Ion Channels on Regulatory T Cell Functions Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. May, 2021 | Pubmed ID: 34043301 Teriflunomide Treatment is Associated with Optic Nerve Recovery in Early Multiple Sclerosis Therapeutic Advances in Neurological Disorders. 2021 | Pubmed ID: 33747129 Neutrophil Granulocytes Promote Flow Stagnation Due to Dynamic Capillary Stalls Following Experimental Stroke Brain, Behavior, and Immunity. Mar, 2021 | Pubmed ID: 33486002 An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis Frontiers in Neurology. 2019 | Pubmed ID: 30881339 Specific T-cell Activation in Peripheral Blood and Cerebrospinal Fluid in Central Disorders of Hypersomnolence Sleep. Feb, 2019 | Pubmed ID: 30445542 TPP2 Mutation Associated with Sterile Brain Inflammation Mimicking MS Neurology. Genetics. Dec, 2018 | Pubmed ID: 30533531 In Vitro Analyses of Novel HCN4 Gene Mutations Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2018 | Pubmed ID: 30196304 Amygdala Enlargement and Emotional Responses in (autoimmune) Temporal Lobe Epilepsy Scientific Reports. Jun, 2018 | Pubmed ID: 29934574 An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function Frontiers in Neurology. 2017 | Pubmed ID: 29033890 Resistance to Renal Denervation Therapy - Identification of Underlying Mechanisms by Analysis of Differential DNA Methylation International Journal of Cardiology. Heart & Vasculature. Jun, 2016 | Pubmed ID: 28616530 Melanocortin-1 Receptor Activation is Neuroprotective in Mouse Models of Neuroinflammatory Disease Science Translational Medicine. Oct, 2016 | Pubmed ID: 27797962 Acute Cholecystitis During Treatment with Alemtuzumab in 3 Patients with RRMS Neurology. Nov, 2016 | Pubmed ID: 27794114 Prothrombin and Factor X Are Elevated in Multiple Sclerosis Patients Annals of Neurology. Oct, 2016 | Pubmed ID: 27774643 Alemtuzumab Treatment Alters Circulating Innate Immune Cells in Multiple Sclerosis Neurology(R) Neuroimmunology & Neuroinflammation. Dec, 2016 | Pubmed ID: 27766281 The Inflammatory Role of Platelets: Translational Insights from Experimental Studies of Autoimmune Disorders International Journal of Molecular Sciences. Oct, 2016 | Pubmed ID: 27754414 14-3-3 Proteins Regulate K2P 5.1 Surface Expression on T Lymphocytes Traffic (Copenhagen, Denmark). Oct, 2016 | Pubmed ID: 27743426 Dichoptic Metacontrast Masking Functions to Infer Transmission Delay in Optic Neuritis PloS One. 2016 | Pubmed ID: 27711139 B7-H1 Shapes T-cell-mediated Brain Endothelial Cell Dysfunction and Regional Encephalitogenicity in Spontaneous CNS Autoimmunity Proceedings of the National Academy of Sciences of the United States of America. Oct, 2016 | Pubmed ID: 27671636 Platelet Derived FasL Contributes to Apoptosis in Stroke Thrombosis and Haemostasis. Oct, 2016 | Pubmed ID: 27608763 Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2 Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2016 | Pubmed ID: 27607061 The Quality of Cortical Network Function Recovery Depends on Localization and Degree of Axonal Demyelination Brain, Behavior, and Immunity. Aug, 2016 | Pubmed ID: 27569659 The Potassium Channels TASK2 and TREK1 Regulate Functional Differentiation of Murine Skeletal Muscle Cells American Journal of Physiology. Cell Physiology. Oct, 2016 | Pubmed ID: 27488672 Distinct Pattern of Lesion Distribution in Multiple Sclerosis is Associated with Different Circulating T-helper and Helper-like Innate Lymphoid Cell Subsets Multiple Sclerosis (Houndmills, Basingstoke, England). Aug, 2016 | Pubmed ID: 27481205 Variations in Multiple Sclerosis Practice Within Europe - Is It Time for a New Treatment Guideline? Multiple Sclerosis and Related Disorders. Jul, 2016 | Pubmed ID: 27456872 General Control Non-derepressible 2 (GCN2) in T Cells Controls Disease Progression of Autoimmune Neuroinflammation Journal of Neuroimmunology. Aug, 2016 | Pubmed ID: 27397084 Novel Multiple Sclerosis Susceptibility Loci Implicated in Epigenetic Regulation Science Advances. Jun, 2016 | Pubmed ID: 27386562 The Farnesoid-X-receptor in Myeloid Cells Controls CNS Autoimmunity in an IL-10-dependent Fashion Acta Neuropathologica. Sep, 2016 | Pubmed ID: 27383204 Thalamocortical-auditory Network Alterations Following Cuprizone-induced Demyelination Journal of Neuroinflammation. Jun, 2016 | Pubmed ID: 27334140 Human T Cells in Silico: Modelling Their Electrophysiological Behaviour in Health and Disease Journal of Theoretical Biology. Sep, 2016 | Pubmed ID: 27288542 Increased Structural White and Grey Matter Network Connectivity Compensates for Functional Decline in Early Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). May, 2016 | Pubmed ID: 27246143 Evidence of a Pathogenic Role for CD8(+) T Cells in Anti-GABAB Receptor Limbic Encephalitis Neurology(R) Neuroimmunology & Neuroinflammation. Jun, 2016 | Pubmed ID: 27213174 Blood Coagulation Factor XII Drives Adaptive Immunity During Neuroinflammation Via CD87-mediated Modulation of Dendritic Cells Nature Communications. May, 2016 | Pubmed ID: 27188843 Impaired NK-mediated Regulation of T-cell Activity in Multiple Sclerosis is Reconstituted by IL-2 Receptor Modulation Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27162345 Failed, Interrupted and Inconclusive Trials on Relapsing Multiple Sclerosis Treatment: Update 2010-2015 Expert Review of Neurotherapeutics. Jun, 2016 | Pubmed ID: 27058174 Editorial: Limbic Encephalitis: Autoimmune Impact on Inhibitory GABAergic Neuronal Pathways in Temporal Lobe Epilepsy Frontiers in Neurology. 2016 | Pubmed ID: 27014186 Simultaneous Early-onset Immune Thrombocytopenia and Autoimmune Thyroid Disease Following Alemtuzumab Treatment in Relapsing-remitting Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Aug, 2016 | Pubmed ID: 26980848 ALAIN01--Alemtuzumab in Autoimmune Inflammatory Neurodegeneration: Mechanisms of Action and Neuroprotective Potential BMC Neurology. Mar, 2016 | Pubmed ID: 26966029 Early Silent Microstructural Degeneration and Atrophy of the Thalamocortical Network in Multiple Sclerosis Human Brain Mapping. May, 2016 | Pubmed ID: 26920497 Clinical Features, Pathogenesis, and Treatment of Myasthenia Gravis: a Supplement to the Guidelines of the German Neurological Society Journal of Neurology. Aug, 2016 | Pubmed ID: 26886206 CD4(+)HLA-G(+) Regulatory T Cells: Molecular Signature and Pathophysiological Relevance Human Immunology. Sep, 2016 | Pubmed ID: 26826445 Sodium Chloride Promotes Pro-inflammatory Macrophage Polarization Thereby Aggravating CNS Autoimmunity Journal of Autoimmunity. Feb, 2016 | Pubmed ID: 26584738 Changes in Different Parameters, Lymphocyte Proliferation and Hematopoietic Progenitor Colony Formation in EAE Mice Treated with Myelin Oligodendrocyte Glycoprotein Journal of Cellular and Molecular Medicine. Jan, 2016 | Pubmed ID: 26493273 PML Risk Stratification Using Anti-JCV Antibody Index and L-selectin Multiple Sclerosis (Houndmills, Basingstoke, England). Jul, 2016 | Pubmed ID: 26432858 Evidence for Early, Non-lesional Cerebellar Damage in Patients with Multiple Sclerosis: DTI Measures Correlate with Disability, Atrophy, and Disease Duration Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2016 | Pubmed ID: 25921041 Fingolimod (FTY720-P) Does Not Stabilize the Blood-Brain Barrier Under Inflammatory Conditions in an in Vitro Model International Journal of Molecular Sciences. 2015 | Pubmed ID: 26690412 The NKG2D-IL-15 Signaling Pathway Contributes to T-cell Mediated Pathology in Inflammatory Myopathies Oncotarget. Dec, 2015 | Pubmed ID: 26646698 An N-terminal Deletion Variant of HCN1 in the Epileptic WAG/Rij Strain Modulates HCN Current Densities Frontiers in Molecular Neuroscience. 2015 | Pubmed ID: 26578877 Case Report of Bilateral Relapsing-remitting Sciatic Nerve Palsy During Two Pregnancies BMC Research Notes. Nov, 2015 | Pubmed ID: 26545719 Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array Genetic Epidemiology. Dec, 2015 | Pubmed ID: 26497834 Effects of Diazoxide in Multiple Sclerosis: A Randomized, Double-blind Phase 2 Clinical Trial Neurology(R) Neuroimmunology & Neuroinflammation. Oct, 2015 | Pubmed ID: 26405686 Early and Degressive Putamen Atrophy in Multiple Sclerosis International Journal of Molecular Sciences. Sep, 2015 | Pubmed ID: 26404239 Neurocognitive Decline in HIV Patients is Associated with Ongoing T-cell Activation in the Cerebrospinal Fluid Annals of Clinical and Translational Neurology. Sep, 2015 | Pubmed ID: 26401512 Physiological Dynamics in Demyelinating Diseases: Unraveling Complex Relationships Through Computer Modeling International Journal of Molecular Sciences. Sep, 2015 | Pubmed ID: 26370960 The Role of Ion Channels in Malignant Brain Tumors Journal of Neuro-oncology. Nov, 2015 | Pubmed ID: 26334315 Limbic Encephalitis: Potential Impact of Adaptive Autoimmune Inflammation on Neuronal Circuits of the Amygdala Frontiers in Neurology. 2015 | Pubmed ID: 26284026 CD8(+) T Cell-Mediated Neuronal Dysfunction and Degeneration in Limbic Encephalitis Frontiers in Neurology. 2015 | Pubmed ID: 26236280 Platelets Induce Apoptosis Via Membrane-bound FasL Blood. Sep, 2015 | Pubmed ID: 26232171 Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation Due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms International Journal of Molecular Sciences. Jul, 2015 | Pubmed ID: 26213925 Alemtuzumab in Multiple Sclerosis: Mechanism of Action and Beyond International Journal of Molecular Sciences. Jul, 2015 | Pubmed ID: 26204829 Blood-brain Barrier Modeling: Challenges and Perspectives Neural Regeneration Research. Jun, 2015 | Pubmed ID: 26199600 Recovery of Thalamic Microstructural Damage After Shiga Toxin 2-associated Hemolytic-uremic Syndrome Journal of the Neurological Sciences. Sep, 2015 | Pubmed ID: 26189050 Effect of Sativex on Spasticity-associated Symptoms in Patients with Multiple Sclerosis Expert Review of Neurotherapeutics. 2015 | Pubmed ID: 26166264 Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein Stem Cell Reports. Jul, 2015 | Pubmed ID: 26143746 The Two-pore Domain K2 P Channel TASK2 Drives Human NK-cell Proliferation and Cytolytic Function European Journal of Immunology. Sep, 2015 | Pubmed ID: 26140335 Assessment of Immune Functions and MRI Disease Activity in Relapsing-remitting Multiple Sclerosis Patients Switching from Natalizumab to Fingolimod (ToFingo-Successor) BMC Neurology. Jun, 2015 | Pubmed ID: 26099927 A Case Report on Juvenile Neuromyelitis Optica: Early Onset, Long Remission Period, and Atypical Treatment Response Neuropediatrics. Aug, 2015 | Pubmed ID: 26058738 Pharmacological Approaches to Delaying Disability Progression in Patients with Multiple Sclerosis Drugs. Jun, 2015 | Pubmed ID: 26033077 Report on the 6th Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Motzen, Germany, Oct. 31th - Nov. 2nd, 2014 Experimental & Translational Stroke Medicine. 2015 | Pubmed ID: 25898363 Thalamic Kv 7 Channels: Pharmacological Properties and Activity Control During Noxious Signal Processing British Journal of Pharmacology. Jun, 2015 | Pubmed ID: 25684311 Blocking of Plasma Kallikrein Ameliorates Stroke by Reducing Thromboinflammation Annals of Neurology. Jan, 2015 | Pubmed ID: 25628066 A Human Post-mortem Brain Model for the Standardization of Multi-centre MRI Studies NeuroImage. Apr, 2015 | Pubmed ID: 25595502 Differential Phospholipase C-dependent Modulation of TASK and TREK Two-pore Domain K+ Channels in Rat Thalamocortical Relay Neurons The Journal of Physiology. Jan, 2015 | Pubmed ID: 25556792 The Role of Two-pore-domain Background K⁺ (K₂p) Channels in the Thalamus Pflugers Archiv : European Journal of Physiology. May, 2015 | Pubmed ID: 25346156 CD28 Superagonist-mediated Boost of Regulatory T Cells Increases Thrombo-inflammation and Ischemic Neurodegeneration During the Acute Phase of Experimental Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2015 | Pubmed ID: 25315859 Clinical Relevance of Specific T-cell Activation in the Blood and Cerebrospinal Fluid of Patients with Mild Alzheimer's Disease Neurobiology of Aging. Jan, 2015 | Pubmed ID: 25277040 Increased Cortical Curvature Reflects White Matter Atrophy in Individual Patients with Early Multiple Sclerosis NeuroImage. Clinical. 2014 | Pubmed ID: 25610761 Long-term Efficacy of Alemtuzumab in Polymyositis Rheumatology (Oxford, England). Dec, 2014 | Pubmed ID: 25552256 Effects of Blood Transportation on Human Peripheral Mononuclear Cell Yield, Phenotype and Function: Implications for Immune Cell Biobanking PloS One. 2014 | Pubmed ID: 25541968 The CNS Under Pathophysiologic Attack-examining the Role of K2P Channels Pflugers Archiv : European Journal of Physiology. Dec, 2014 | Pubmed ID: 25482672 The Two-pore Domain Potassium Channel KCNK5 Deteriorates Outcome in Ischemic Neurodegeneration Pflugers Archiv : European Journal of Physiology. Oct, 2014 | Pubmed ID: 25315980 Differential Phospholipase C-dependent Modulation of TASK and TREK Two-pore Domain K+ Channels in Rat Thalamocortical Relay Neurons The Journal of Physiology. Oct, 2014 | Pubmed ID: 25281730 C1-Inhibitor Protects from Focal Brain Trauma in a Cortical Cryolesion Mice Model by Reducing Thrombo-inflammation Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25249935 Transient Receptor Potential Melastatin Subfamily Member 2 Cation Channel Regulates Detrimental Immune Cell Invasion in Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Nov, 2014 | Pubmed ID: 25236871 Regionally Specific Expression of High-voltage-activated Calcium Channels in Thalamic Nuclei of Epileptic and Non-epileptic Rats Molecular and Cellular Neurosciences. Jul, 2014 | Pubmed ID: 24914823 Effects of Glatiramer Acetate in a Spontaneous Model of Autoimmune Neuroinflammation The American Journal of Pathology. Jul, 2014 | Pubmed ID: 24819960 Phospholipase D1 Mediates Lymphocyte Adhesion and Migration in Experimental Autoimmune Encephalomyelitis European Journal of Immunology. Aug, 2014 | Pubmed ID: 24811005 Ultraviolet B Light Attenuates the Systemic Immune Response in Central Nervous System Autoimmunity Annals of Neurology. May, 2014 | Pubmed ID: 24771567 Human CD4+ HLA-G+ Regulatory T Cells Are Potent Suppressors of Graft-versus-host Disease in Vivo FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2014 | Pubmed ID: 24744146 Blocking of α4 Integrin Does Not Protect from Acute Ischemic Stroke in Mice Stroke; a Journal of Cerebral Circulation. Jun, 2014 | Pubmed ID: 24743435 Early Detection of Widespread Progressive Brain Injury After Cardiac Arrest: A Single Case DTI and Post-Mortem Histology Study PloS One. 2014 | Pubmed ID: 24633135 Glatiramer Acetate Does Not Protect from Acute Ischemic Stroke in Mice Experimental & Translational Stroke Medicine. 2014 | Pubmed ID: 24576335 TREK-King the Blood-Brain-Barrier Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Feb, 2014 | Pubmed ID: 24557892 Ischemia-induced Cell Depolarization: Does the Hyperpolarization-activated Cation Channel HCN2 Affect the Outcome After Stroke in Mice? Experimental & Translational Stroke Medicine. 2013 | Pubmed ID: 24373160 Report on the 5'th Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013 Experimental & Translational Stroke Medicine. 2013 | Pubmed ID: 24330587 Evans Syndrome Associated with Sterile Inflammation of the Central Nervous System: a Case Report Journal of Medical Case Reports. 2013 | Pubmed ID: 24299473 CD4+NKG2D+ T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation PloS One. 2013 | Pubmed ID: 24282598 A Splice Variant of the Two-pore Domain Potassium Channel TREK-1 with Only One Pore Domain Reduces the Surface Expression of Full-length TREK-1 Channels Pflugers Archiv : European Journal of Physiology. Nov, 2013 | Pubmed ID: 24196565 DTI Detects Water Diffusion Abnormalities in the Thalamus That Correlate with an Extremity Pain Episode in a Patient with Multiple Sclerosis NeuroImage. Clinical. 2013 | Pubmed ID: 24179780 Excitotoxic Neuronal Cell Death During an Oligodendrocyte-directed CD8+ T Cell Attack in the CNS Gray Matter Journal of Neuroinflammation. 2013 | Pubmed ID: 24093512 FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-inflammation but Not by Direct Neuroprotection Stroke; a Journal of Cerebral Circulation. Nov, 2013 | Pubmed ID: 24029635 Targeting Ion Channels for the Treatment of Autoimmune Neuroinflammation Therapeutic Advances in Neurological Disorders. Sep, 2013 | Pubmed ID: 23997817 Protein Kinase Cβ As a Therapeutic Target Stabilizing Blood-brain Barrier Disruption in Experimental Autoimmune Encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. Sep, 2013 | Pubmed ID: 23959874 Endothelial TWIK-related Potassium Channel-1 (TREK1) Regulates Immune-cell Trafficking into the CNS Nature Medicine. Sep, 2013 | Pubmed ID: 23933981 L-Selectin is a Possible Biomarker for Individual PML Risk in Natalizumab-treated MS Patients Neurology. Aug, 2013 | Pubmed ID: 23925765 Rasmussen Encephalitis Treated with Natalizumab Neurology. Jul, 2013 | Pubmed ID: 23794679 4-Aminopyridine Ameliorates Mobility but Not Disease Course in an Animal Model of Multiple Sclerosis Experimental Neurology. Oct, 2013 | Pubmed ID: 23748135 The Phosphodiesterase-4 Inhibitor Rolipram Protects from Ischemic Stroke in Mice by Reducing Blood-brain-barrier Damage, Inflammation and Thrombosis Experimental Neurology. Sep, 2013 | Pubmed ID: 23570902 Thalamic Involvement in Patients with Neurologic Impairment Due to Shiga Toxin 2 Annals of Neurology. Mar, 2013 | Pubmed ID: 23424019 Correction: Two Pore Domain Potassium Channels in Cerebral Ischemia: a Focus on K2P9.1 (TASK3, KCNK9) Experimental & Translational Stroke Medicine. 2013 | Pubmed ID: 23374257 Ca(2+)-dependent Large Conductance K(+) Currents in Thalamocortical Relay Neurons of Different Rat Strains Pflügers Archiv : European Journal of Physiology. Apr, 2013 | Pubmed ID: 23207578 Regulatory T Cells Are Strong Promoters of Acute Ischemic Stroke in Mice by Inducing Dysfunction of the Cerebral Microvasculature Blood. Jan, 2013 | Pubmed ID: 23160472 Identification of Two-pore Domain Potassium Channels As Potent Modulators of Osmotic Volume Regulation in Human T Lymphocytes Biochimica Et Biophysica Acta. Feb, 2013 | Pubmed ID: 23041580 Paraneoplastic and Non-paraneoplastic Autoimmunity to Neurons in the Central Nervous System Journal of Neurology. May, 2013 | Pubmed ID: 22983427 Report on the 4'th Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012 Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 23174128 The TASK1 Channel Inhibitor A293 Shows Efficacy in a Mouse Model of Multiple Sclerosis Experimental Neurology. Dec, 2012 | Pubmed ID: 22960185 Kininogen Deficiency Protects from Ischemic Neurodegeneration in Mice by Reducing Thrombosis, Blood-brain Barrier Damage, and Inflammation Blood. Nov, 2012 | Pubmed ID: 22936662 Cytotoxic CD8+ T Cells and CD138+ Plasma Cells Prevail in Cerebrospinal Fluid in Non-paraneoplastic Cerebellar Ataxia with Contactin-associated Protein-2 Antibodies Journal of Neuroinflammation. 2012 | Pubmed ID: 22759321 C1-inhibitor Protects from Brain Ischemia-reperfusion Injury by Combined Antiinflammatory and Antithrombotic Mechanisms Stroke; a Journal of Cerebral Circulation. Sep, 2012 | Pubmed ID: 22744646 Immune Therapy of Multiple Sclerosis--future Strategies Current Pharmaceutical Design. 2012 | Pubmed ID: 22612746 Blocking of Bradykinin Receptor B1 Protects from Focal Closed Head Injury in Mice by Reducing Axonal Damage and Astroglia Activation Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2012 | Pubmed ID: 22569191 Adenylyl Cyclases: Expression in the Developing Rat Thalamus and Their Role in Absence Epilepsy Journal of Molecular Neuroscience : MN. Sep, 2012 | Pubmed ID: 22531884 Neuron-directed Autoimmunity in the Central Nervous System: Entities, Mechanisms, Diagnostic Clues, and Therapeutic Options Current Opinion in Neurology. Jun, 2012 | Pubmed ID: 22487567 Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis Circulation Research. Apr, 2012 | Pubmed ID: 22456181 CD4(+) CD25(+) FoxP3(+) Regulatory T Cells Suppress Cytotoxicity of CD8(+) Effector T Cells: Implications for Their Capacity to Limit Inflammatory Central Nervous System Damage at the Parenchymal Level Journal of Neuroinflammation. 2012 | Pubmed ID: 22373353 Report on the 3'rd Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011 Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 22360825 CD4(+) T Cells Predominate in Cerebrospinal Fluid and Leptomeningeal and Parenchymal Infiltrates in Cerebral Amyloid β-related Angiitis Archives of Neurology. Jun, 2012 | Pubmed ID: 22351850 Cytosolic RIG-I-like Helicases Act As Negative Regulators of Sterile Inflammation in the CNS Nature Neuroscience. Jan, 2012 | Pubmed ID: 22138643 Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 Integrin Mediates Interaction of Melanoma Cells with Platelets: A CONNECTION TO HEMATOGENOUS METASTASIS The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22102277 Identification of the Muscarinic Pathway Underlying Cessation of Sleep-related Burst Activity in Rat Thalamocortical Relay Neurons Pflügers Archiv : European Journal of Physiology. Jan, 2012 | Pubmed ID: 22083644 Immunological and Clinical Consequences of Treating a Patient with Natalizumab Multiple Sclerosis (Houndmills, Basingstoke, England). Mar, 2012 | Pubmed ID: 21908480 Immune Mechanisms of New Therapeutic Strategies in Multiple Sclerosis-A Focus on Alemtuzumab Clinical Immunology (Orlando, Fla.). Jan, 2012 | Pubmed ID: 21550857 Modulation of Calcium-dependent Inactivation of L-type Ca2+ Channels Via β-adrenergic Signaling in Thalamocortical Relay Neurons PloS One. 2011 | Pubmed ID: 22164209 Knock-out of the Potassium Channel TASK-1 Leads to a Prolonged QT Interval and a Disturbed QRS Complex Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2011 | Pubmed ID: 21865850 Volume Regulation of Murine T Lymphocytes Relies on Voltage-dependent and Two-pore Domain Potassium Channels Biochimica Et Biophysica Acta. Aug, 2011 | Pubmed ID: 21575593 Ion Channels in Autoimmune Neurodegeneration FEBS Letters. Dec, 2011 | Pubmed ID: 21501610 Report on the 2nd Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010 Experimental & Translational Stroke Medicine. 2011 | Pubmed ID: 21457546 A-type K+ Currents in Intralaminar Thalamocortical Relay Neurons Pflügers Archiv : European Journal of Physiology. May, 2011 | Pubmed ID: 21437601 Glucocorticoid Insensitivity at the Hypoxic Blood-brain Barrier Can Be Reversed by Inhibition of the Proteasome Stroke; a Journal of Cerebral Circulation. Apr, 2011 | Pubmed ID: 21330632 No Association Between Genetic Polymorphism at Codon 129 of the Prion Protein Gene and Primary Progressive Multiple Sclerosis Archives of Neurology. Feb, 2011 | Pubmed ID: 21320996 Expression of K2P5.1 Potassium Channels on CD4+ T Lymphocytes Correlates with Disease Activity in Rheumatoid Arthritis Patients Arthritis Research & Therapy. 2011 | Pubmed ID: 21314928 Blockade of the Kinin Receptor B1 Protects from Autoimmune CNS Disease by Reducing Leukocyte Trafficking Journal of Autoimmunity. Mar, 2011 | Pubmed ID: 21216565 Active Immunization with Proteolipid Protein (190-209) Induces Ascending Paralysing Experimental Autoimmune Encephalomyelitis in C3H/HeJ Mice Journal of Immunological Methods. Mar, 2011 | Pubmed ID: 21199659 Natalizumab Restores Evoked Potential Abnormalities in Patients with Relapsing-remitting Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2011 | Pubmed ID: 21135021 Activity Modes in Thalamocortical Relay Neurons Are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling Frontiers in Cellular Neuroscience. 2010 | Pubmed ID: 21267426 Temporal Pattern of ICAM-I Mediated Regulatory T Cell Recruitment to Sites of Inflammation in Adoptive Transfer Model of Multiple Sclerosis PloS One. 2010 | Pubmed ID: 21085578 Glatiramer Acetate Attenuates Pro-inflammatory T Cell Responses but Does Not Directly Protect Neurons from Inflammatory Cell Death The American Journal of Pathology. Dec, 2010 | Pubmed ID: 21037084 Post-stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration PLoS Biology. 2010 | Pubmed ID: 20877715 Therapeutic Approaches to Multiple Sclerosis: an Update on Failed, Interrupted, or Inconclusive Trials of Neuroprotective and Alternative Treatment Strategies BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. Oct, 2010 | Pubmed ID: 20795753 Two Pore Domain Potassium Channels in Cerebral Ischemia: a Focus on K2P9.1 (TASK3, KCNK9) Experimental & Translational Stroke Medicine. 2010 | Pubmed ID: 20646278 Therapeutic Approaches to Multiple Sclerosis: an Update on Failed, Interrupted, or Inconclusive Trials of Immunomodulatory Treatment Strategies BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. Aug, 2010 | Pubmed ID: 20623991 Upregulation of K2P5.1 Potassium Channels in Multiple Sclerosis Annals of Neurology. Jul, 2010 | Pubmed ID: 20582984 From the Background to the Spotlight: TASK Channels in Pathological Conditions Brain Pathology (Zurich, Switzerland). Nov, 2010 | Pubmed ID: 20529081 Report on the 1st Scientific Meeting of the "Verein Zur Förderung Des Wissenschaftlichen Nachwuchses in Der Neurologie" (NEUROWIND E.V.) Held in Mittenwalde/Motzen, Germany, Oct. 30th - Nov. 1st, 2009 Experimental & Translational Stroke Medicine. 2010 | Pubmed ID: 20356357 A Pure Cerebellar Syndrome with Corresponding Ponto-cerebellar Atrophy in Acquired Hepatocerebral Degeneration Journal of the Neurological Sciences. May, 2010 | Pubmed ID: 20233618 Inhibition of Bradykinin Receptor B1 Protects Mice from Focal Brain Injury by Reducing Blood-brain Barrier Leakage and Inflammation Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2010 | Pubmed ID: 20197781 Multifocal Motor Neuropathy: Update on Clinical Characteristics, Pathophysiological Concepts and Therapeutic Options European Neurology. 2010 | Pubmed ID: 20150737 Deficiency of the Negative Immune Regulator B7-H1 Enhances Inflammation and Neuropathic Pain After Chronic Constriction Injury of Mouse Sciatic Nerve Experimental Neurology. Mar, 2010 | Pubmed ID: 20051242 Stromal Interaction Molecules 1 and 2 Are Key Regulators of Autoreactive T Cell Activation in Murine Autoimmune Central Nervous System Inflammation Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20028655 Collateral Neuronal Apoptosis in CNS Gray Matter During an Oligodendrocyte-directed CD8(+) T Cell Attack Glia. Mar, 2010 | Pubmed ID: 19780193 Immunotherapy of Multiple Sclerosis Acta Neuropsychiatrica. Jun, 2009 | Pubmed ID: 25384864 Cytotoxic CD8+ T Cell-neuron Interactions: Perforin-dependent Electrical Silencing Precedes but is Not Causally Linked to Neuronal Cell Death The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2009 | Pubmed ID: 20007464 STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death Science Signaling. 2009 | Pubmed ID: 19843959 Comment on "Functional Consequences of Kv1.3 Ion Channel Rearrangement into the Immunological Synapse" Immunology Letters. Aug, 2009 | Pubmed ID: 19595706 TASK1 Modulates Inflammation and Neurodegeneration in Autoimmune Inflammation of the Central Nervous System Brain : a Journal of Neurology. Sep, 2009 | Pubmed ID: 19570851 CD8+ T Cells and Neuronal Damage: Direct and Collateral Mechanisms of Cytotoxicity and Impaired Electrical Excitability FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2009 | Pubmed ID: 19567369 Antigen-specific Blockade of Lethal CD8 T-cell Mediated Autoimmunity in a Mouse Model of Multiple Sclerosis Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19414812 Platelet Derived BFGF Mediates Vascular Integrative Mechanisms of Mesenchymal Stem Cells in Vitro Journal of Molecular and Cellular Cardiology. Aug, 2009 | Pubmed ID: 19328809 Intercellular Exchanges of Membrane Fragments (trogocytosis) Between Human Muscle Cells and Immune Cells: a Potential Mechanism for the Modulation of Muscular Immune Responses Journal of Neuroimmunology. Apr, 2009 | Pubmed ID: 19269695 Transient Widespread Blood-brain Barrier Alterations After Cerebral Photothrombosis As Revealed by Gadofluorine M-enhanced Magnetic Resonance Imaging Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2009 | Pubmed ID: 18957988 The Neuroprotective Impact of the Leak Potassium Channel TASK1 on Stroke Development in Mice Neurobiology of Disease. Jan, 2009 | Pubmed ID: 18930826 Mismatch and Conflict: Neurophysiological and Behavioral Evidence for Conflict Priming Journal of Cognitive Neuroscience. Nov, 2009 | Pubmed ID: 18855548 Recent Clinical Trials and Future Therapies Journal of Neurology. Dec, 2008 | Pubmed ID: 19300967 Altered Neuronal Expression of TASK1 and TASK3 Potassium Channels in Rodent and Human Autoimmune CNS Inflammation Neuroscience Letters. Dec, 2008 | Pubmed ID: 18824070 The Trials and Errors in MS Therapy International MS Journal / MS Forum. Sep, 2008 | Pubmed ID: 18808741 A Beta-lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis PloS One. 2008 | Pubmed ID: 18773080 Detrimental Contribution of the Immuno-inhibitor B7-H1 to Rabies Virus Encephalitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18490751 Reciprocal Modulation of I (h) and I (TASK) in Thalamocortical Relay Neurons by Halothane Pflügers Archiv : European Journal of Physiology. Sep, 2008 | Pubmed ID: 18478257 TWIK-related Acid-sensitive K+ Channel 1 (TASK1) and TASK3 Critically Influence T Lymphocyte Effector Functions The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18375952 Muscarinic ACh Receptor-mediated Control of Thalamic Activity Via G(q)/G (11)-family G-proteins Pflügers Archiv : European Journal of Physiology. Sep, 2008 | Pubmed ID: 18350314 The Two-pore Domain Potassium Channel TASK3 Functionally Impacts Glioma Cell Death Journal of Neuro-oncology. May, 2008 | Pubmed ID: 18217213 CNS Inflammation and Neuronal Degeneration is Aggravated by Impaired CD200-CD200R-mediated Macrophage Silencing Journal of Neuroimmunology. Feb, 2008 | Pubmed ID: 18164423 Multiple Sclerosis Therapy: an Update on Recently Finished Trials Journal of Neurology. Nov, 2007 | Pubmed ID: 18004638 Specific Expression of Low-voltage-activated Calcium Channel Isoforms and Splice Variants in Thalamic Local Circuit Interneurons Molecular and Cellular Neurosciences. Oct, 2007 | Pubmed ID: 17707654 T-current Related Effects of Antiepileptic Drugs and a Ca2+ Channel Antagonist on Thalamic Relay and Local Circuit Interneurons in a Rat Model of Absence Epilepsy Neuropharmacology. Sep, 2007 | Pubmed ID: 17675191 Membrane Resting Potential of Thalamocortical Relay Neurons is Shaped by the Interaction Among TASK3 and HCN2 Channels Journal of Neurophysiology. Sep, 2006 | Pubmed ID: 16760342 T Cell Infiltration After Chronic Constriction Injury of Mouse Sciatic Nerve is Associated with Interleukin-17 Expression Experimental Neurology. Aug, 2006 | Pubmed ID: 16674943 Effects of Divalent Cations and Spermine on the K+ Channel TASK-3 and on the Outward Current in Thalamic Neurons The Journal of Physiology. May, 2006 | Pubmed ID: 16513667 The Contribution of TWIK-related Acid-sensitive K+-containing Channels to the Function of Dorsal Lateral Geniculate Thalamocortical Relay Neurons Molecular Pharmacology. Apr, 2006 | Pubmed ID: 16424077 Get the Rhythm: Modeling Neuronal Activity Journal of Undergraduate Neuroscience Education : JUNE : a Publication of FUN, Faculty for Undergraduate Neuroscience. 2005 | Pubmed ID: 23493337 Influence of Ca2+-binding Proteins and the Cytoskeleton on Ca2+-dependent Inactivation of High-voltage Activated Ca2+ Currents in Thalamocortical Relay Neurons Pflügers Archiv : European Journal of Physiology. May, 2005 | Pubmed ID: 15647929 Modulation of Neuronal Activity by the Endogenous Pentapeptide QYNAD The European Journal of Neuroscience. Nov, 2003 | Pubmed ID: 14656318 Contribution of TWIK-related Acid-sensitive K+ Channel 1 (TASK1) and TASK3 Channels to the Control of Activity Modes in Thalamocortical Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12878686 Studying Neuroinflammatory Pathways Through Simultaneous Isolation of All Main CNS-Resident Cell Types (Video) | JoVE Christina B. Schroeter*1, Antonia Henes*1, Anna Vogelsang1, Alexander M. Herrmann1, Stefanie Lichtenberg1, Derya Cengiz1, Vera Dobelmann1, Niklas Huntemann1, Christopher Nelke1, Susann Eichler2, Philipp Albrecht1, Sven G. Meuth*1, Tobias Ruck1 1Department of Neurology, Medical Faculty, Heinrich Heine University Duesseldorf, 2Department of Neurology, Institute of Translational Neurology, University Hospital Muenster JoVE 65735 신경과학 Isolation of Primary Murine Skeletal Muscle Microvascular Endothelial Cells Thomas Müntefering*1, Alexander P.E. Michels*1, Steffen Pfeuffer1, Sven G. Meuth*1, Tobias Ruck*1 1Institute for Translational Neurology and Neurology Clinic, University of Muenster JoVE 58901 신경과학 An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction Ivan Kuzmanov1, Alexander M. Herrmann1, Hans-Joachim Galla2, Sven G. Meuth1, Heinz Wiendl*1, Luisa Klotz*1 1Department of Neurology, University Hospital Münster, 2Institute of Biochemistry, University of Münster JoVE 54592 면역학 및 감염병학 An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices Kerstin Göbel1, Stefan Bittner1,2, Manuela Cerina3, Alexander M. Herrmann1, Heinz Wiendl1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Germany and Interdisciplinary Center for Clinical Research (IZKF) Münster, 3Institute of Physiology I - Neuropathophysiology I, University of Münster JoVE 52205 면역학 및 감염병학 Isolation of Primary Murine Brain Microvascular Endothelial Cells Tobias Ruck1, Stefan Bittner1,2, Lisa Epping1, Alexander M. Herrmann1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF) Münster, 3Institute of Physiology I — Neuropathophysiology I, University of Münster JoVE 52204 신경과학 Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice Stefan Bittner1,2, Ali M. Afzali1, Heinz Wiendl1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster JoVE 51275 면역학 및 감염병학
Studying Neuroinflammatory Pathways Through Simultaneous Isolation of All Main CNS-Resident Cell Types (Video) | JoVE Christina B. Schroeter*1, Antonia Henes*1, Anna Vogelsang1, Alexander M. Herrmann1, Stefanie Lichtenberg1, Derya Cengiz1, Vera Dobelmann1, Niklas Huntemann1, Christopher Nelke1, Susann Eichler2, Philipp Albrecht1, Sven G. Meuth*1, Tobias Ruck1 1Department of Neurology, Medical Faculty, Heinrich Heine University Duesseldorf, 2Department of Neurology, Institute of Translational Neurology, University Hospital Muenster JoVE 65735 신경과학
Isolation of Primary Murine Skeletal Muscle Microvascular Endothelial Cells Thomas Müntefering*1, Alexander P.E. Michels*1, Steffen Pfeuffer1, Sven G. Meuth*1, Tobias Ruck*1 1Institute for Translational Neurology and Neurology Clinic, University of Muenster JoVE 58901 신경과학
An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction Ivan Kuzmanov1, Alexander M. Herrmann1, Hans-Joachim Galla2, Sven G. Meuth1, Heinz Wiendl*1, Luisa Klotz*1 1Department of Neurology, University Hospital Münster, 2Institute of Biochemistry, University of Münster JoVE 54592 면역학 및 감염병학
An Ex vivo Model of an Oligodendrocyte-directed T-Cell Attack in Acute Brain Slices Kerstin Göbel1, Stefan Bittner1,2, Manuela Cerina3, Alexander M. Herrmann1, Heinz Wiendl1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Germany and Interdisciplinary Center for Clinical Research (IZKF) Münster, 3Institute of Physiology I - Neuropathophysiology I, University of Münster JoVE 52205 면역학 및 감염병학
Isolation of Primary Murine Brain Microvascular Endothelial Cells Tobias Ruck1, Stefan Bittner1,2, Lisa Epping1, Alexander M. Herrmann1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF) Münster, 3Institute of Physiology I — Neuropathophysiology I, University of Münster JoVE 52204 신경과학
Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice Stefan Bittner1,2, Ali M. Afzali1, Heinz Wiendl1, Sven G. Meuth1,3 1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster JoVE 51275 면역학 및 감염병학