Sven Hammerschmidt Department Genetics of Microorganisms, Interfaculty Institute for Genetics and Functional Genomics University of Greifswald Biography Publications Institution JoVE Articles Sven Hammerschmidt has not added a biography. If you are Sven Hammerschmidt and would like to personalize this page please email our Author Liaison for assistance. Publications Influence of Impaired Lipoprotein Biogenesis on Surface and Exoproteome of Streptococcus Pneumoniae Journal of Proteome Research. Feb, 2014 | Pubmed ID: 24387739 Repeating Structures of the Major Staphylococcal Autolysin Are Essential for the Interaction with Human Thrombospondin 1 and Vitronectin The Journal of Biological Chemistry. Feb, 2014 | Pubmed ID: 24371140 Molecular Architecture of Streptococcus Pneumoniae Surface Thioredoxin-fold Lipoproteins Crucial for Extracellular Oxidative Stress Resistance and Maintenance of Virulence EMBO Molecular Medicine. Dec, 2013 | Pubmed ID: 24136784 Exploitation of Physiology and Metabolomics to Identify Pneumococcal Vaccine Candidates Expert Review of Vaccines. Sep, 2013 | Pubmed ID: 24053399 The Interaction Between Bacterial Enolase and Plasminogen Promotes Adherence of Streptococcus Pneumoniae to Epithelial and Endothelial Cells International Journal of Medical Microbiology : IJMM. Dec, 2013 | Pubmed ID: 23906818 Lung Dendritic Cells Facilitate Extrapulmonary Bacterial Dissemination During Pneumococcal Pneumonia Frontiers in Cellular and Infection Microbiology. 2013 | Pubmed ID: 23802100 Structural Reevaluation of Streptococcus Pneumoniae Lipoteichoic Acid and New Insights into Its Immunostimulatory Potency The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23603911 The Choline-binding Protein PspC of Streptococcus Pneumoniae Interacts with the C-terminal Heparin-binding Domain of Vitronectin The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23603906 High Mobility Group Box 1 Prolongs Inflammation and Worsens Disease in Pneumococcal Meningitis Brain : a Journal of Neurology. Jun, 2013 | Pubmed ID: 23518713 TLR9- and Src-dependent Expression of Krueppel-like Factor 4 Controls Interleukin-10 Expression in Pneumonia The European Respiratory Journal. Feb, 2013 | Pubmed ID: 22653776 Platelet Factor 4 Binding to Lipid A of Gram-negative Bacteria Exposes PF4/heparin-like Epitopes Blood. Oct, 2012 | Pubmed ID: 22942185 Enolase of Streptococcus Pneumoniae Binds Human Complement Inhibitor C4b-binding Protein and Contributes to Complement Evasion Journal of Immunology (Baltimore, Md. : 1950). Oct, 2012 | Pubmed ID: 22925928 Tumor Necrosis Factor Alpha Modulates the Dynamics of the Plasminogen-mediated Early Interaction Between Bifidobacterium Animalis Subsp. Lactis and Human Enterocytes Applied and Environmental Microbiology. Apr, 2012 | Pubmed ID: 22287006 Heterologous Expression of Pneumococcal Virulence Factor PspC on the Surface of Lactococcus Lactis Confers Adhesive Properties Microbiology (Reading, England). Mar, 2012 | Pubmed ID: 22222496 Combat Pneumococcal Infections: Adhesins As Candidates for Protein-based Vaccine Development Current Drug Targets. Mar, 2012 | Pubmed ID: 22206255 Characterization of Central Carbon Metabolism of Streptococcus Pneumoniae by Isotopologue Profiling The Journal of Biological Chemistry. Feb, 2012 | Pubmed ID: 22167202 Streptococcus Pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-dependent Type I IFN Production in Macrophages, Which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs Journal of Immunology (Baltimore, Md. : 1950). Jan, 2012 | Pubmed ID: 22156592 Streptococcus Pneumoniae Induces Exocytosis of Weibel-Palade Bodies in Pulmonary Endothelial Cells Cellular Microbiology. Feb, 2012 | Pubmed ID: 21999205 The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and is Activated Through ATP-dependent Lysosomal Cathepsin B Release Journal of Immunology (Baltimore, Md. : 1950). Nov, 2011 | Pubmed ID: 22003197 Relevance of Bifidobacterium Animalis Subsp. Lactis Plasminogen Binding Activity in the Human Gastrointestinal Microenvironment Applied and Environmental Microbiology. Oct, 2011 | Pubmed ID: 21821753 Association of Natural Anti-platelet Factor 4/heparin Antibodies with Periodontal Disease Blood. Aug, 2011 | Pubmed ID: 21659541 Streptococcus Pneumoniae Infection of Host Epithelial Cells Via Polymeric Immunoglobulin Receptor Transiently Induces Calcium Release from Intracellular Stores The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454571 Mast Cells Increase Vascular Permeability by Heparin-initiated Bradykinin Formation In vivo Immunity. Feb, 2011 | Pubmed ID: 21349432 Genomic Organization, Structure, Regulation and Pathogenic Role of Pilus Constituents in Major Pathogenic Streptococci and Enterococci International Journal of Medical Microbiology : IJMM. Mar, 2011 | Pubmed ID: 21112248 Impact of Glutamine Transporters on Pneumococcal Fitness Under Infection-related Conditions Infection and Immunity. Jan, 2011 | Pubmed ID: 21078855 Platelet Factor 4 Binds to Bacteria, [corrected] Inducing Antibodies Cross-reacting with the Major Antigen in Heparin-induced Thrombocytopenia Blood. Jan, 2011 | Pubmed ID: 20959601 Polymeric Immunoglobulin Receptor-mediated Invasion of Streptococcus Pneumoniae into Host Cells Requires a Coordinate Signaling of SRC Family of Protein-tyrosine Kinases, ERK, and C-Jun N-terminal Kinase The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20829350 TLR2- and Nucleotide-binding Oligomerization Domain 2-dependent Krüppel-like Factor 2 Expression Downregulates NF-kappa B-related Gene Expression Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010 | Pubmed ID: 20525885 Complement Regulator Factor H Mediates a Two-step Uptake of Streptococcus Pneumoniae by Human Cells The Journal of Biological Chemistry. Jul, 2010 | Pubmed ID: 20504767 PavB is a Surface-exposed Adhesin of Streptococcus Pneumoniae Contributing to Nasopharyngeal Colonization and Airways Infections Molecular Microbiology. Jul, 2010 | Pubmed ID: 20444103 DnaK from Bifidobacterium Animalis Subsp. Lactis is a Surface-exposed Human Plasminogen Receptor Upregulated in Response to Bile Salts Microbiology (Reading, England). Jun, 2010 | Pubmed ID: 20167618 Toll-like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus Pneumoniae by Murine Microglia Infection and Immunity. Feb, 2010 | Pubmed ID: 19933834 Fibronectin Stimulates Escherichia Coli Phagocytosis by Microglial Cells Glia. Feb, 2010 | Pubmed ID: 19780198 Pneumococcal Association to Platelets is Mediated by Soluble Fibrin and Supported by Thrombospondin-1 Thrombosis and Haemostasis. Oct, 2009 | Pubmed ID: 19806260 Bifidobacterial Enolase, a Cell Surface Receptor for Human Plasminogen Involved in the Interaction with the Host Microbiology (Reading, England). Oct, 2009 | Pubmed ID: 19574304 Pneumococcal Interaction with Human Dendritic Cells: Phagocytosis, Survival, and Induced Adaptive Immune Response Are Manipulated by PavA Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19570831 Cdc42 and the Phosphatidylinositol 3-kinase-Akt Pathway Are Essential for PspC-mediated Internalization of Pneumococci by Respiratory Epithelial Cells The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19473971 Defining the Structural Basis of Human Plasminogen Binding by Streptococcal Surface Enolase The Journal of Biological Chemistry. Jun, 2009 | Pubmed ID: 19363026 Integrin-linked Kinase is Required for Vitronectin-mediated Internalization of Streptococcus Pneumoniae by Host Cells Journal of Cell Science. Jan, 2009 | Pubmed ID: 19118218 Surface-exposed Adherence Molecules of Streptococcus Pneumoniae Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19089373 Toll-like Receptor Prestimulation Increases Phagocytosis of Escherichia Coli DH5alpha and Escherichia Coli K1 Strains by Murine Microglial Cells Infection and Immunity. Jan, 2009 | Pubmed ID: 18981243 The Complement Fitness Factor H: Role in Human Diseases and for Immune Escape of Pathogens, Like Pneumococci Vaccine. Dec, 2008 | Pubmed ID: 19388168 Plasminogen-dependent Proteolytic Activity in Bifidobacterium Lactis Microbiology (Reading, England). Aug, 2008 | Pubmed ID: 18667578 The Surface-associated Elongation Factor Tu is Concealed for Antibody Binding on Viable Pneumococci and Meningococci FEMS Immunology and Medical Microbiology. Jul, 2008 | Pubmed ID: 18462389 Fibrinolysis and Host Response in Bacterial Infections Thrombosis and Haemostasis. Sep, 2007 | Pubmed ID: 17849039 Cell-specific Interleukin-15 and Interleukin-15 Receptor Subunit Expression and Regulation in Pneumococcal Pneumonia--comparison to Chlamydial Lung Infection Cytokine. May, 2007 | Pubmed ID: 17611121 Binding of Human Plasminogen to Bifidobacterium Journal of Bacteriology. Aug, 2007 | Pubmed ID: 17557824 Thrombospondin-1 Promotes Cellular Adherence of Gram-positive Pathogens Via Recognition of Peptidoglycan FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2007 | Pubmed ID: 17507668 The Host Immune Regulator Factor H Interacts Via Two Contact Sites with the PspC Protein of Streptococcus Pneumoniae and Mediates Adhesion to Host Epithelial Cells Journal of Immunology (Baltimore, Md. : 1950). May, 2007 | Pubmed ID: 17442969 Cytosolic Proteins Contribute to Surface Plasminogen Recruitment of Neisseria Meningitidis Journal of Bacteriology. Apr, 2007 | Pubmed ID: 17307854 Regulation of Production of Mucosal Antibody to Pneumococcal Protein Antigens by T-cell-derived Gamma Interferon and Interleukin-10 in Children Infection and Immunity. Aug, 2006 | Pubmed ID: 16861661 Streptococcus Pneumoniae Enolase is Important for Plasminogen Binding Despite Low Abundance of Enolase Protein on the Bacterial Cell Surface Microbiology (Reading, England). May, 2006 | Pubmed ID: 16622048 Versatility of Pneumococcal Surface Proteins Microbiology (Reading, England). Feb, 2006 | Pubmed ID: 16436417 Identification of a Polymeric Ig Receptor Binding Phage-displayed Peptide That Exploits Epithelial Transcytosis Without Dimeric IgA Competition The Journal of Biological Chemistry. Mar, 2006 | Pubmed ID: 16423833 Adherence Molecules of Pathogenic Pneumococci Current Opinion in Microbiology. Feb, 2006 | Pubmed ID: 16338163 Pneumococci Induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 Promoter in Lung Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2006 | Pubmed ID: 16299055 The Streptococcal Lipoprotein Rotamase A (SlrA) is a Functional Peptidyl-prolyl Isomerase Involved in Pneumococcal Colonization The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16260779 The Nine Residue Plasminogen-binding Motif of the Pneumococcal Enolase is the Major Cofactor of Plasmin-mediated Degradation of Extracellular Matrix, Dissolution of Fibrin and Transmigration Thrombosis and Haemostasis. Aug, 2005 | Pubmed ID: 16113819 Streptococcus Pneumoniae R6x Induced P38 MAPK and JNK-mediated Caspase-dependent Apoptosis in Human Endothelial Cells Thrombosis and Haemostasis. Aug, 2005 | Pubmed ID: 16113818 Threat of Infection: Microbes of High Pathogenic Potential--strategies for Detection, Control and Eradication International Journal of Medical Microbiology : IJMM. Jun, 2005 | Pubmed ID: 16044855 Illustration of Pneumococcal Polysaccharide Capsule During Adherence and Invasion of Epithelial Cells Infection and Immunity. Aug, 2005 | Pubmed ID: 16040978 Cloning, Characterization and DNA Immunization of an Onchocerca Volvulus Glyceraldehyde-3-phosphate Dehydrogenase (Ov-GAPDH) Biochimica Et Biophysica Acta. Jun, 2005 | Pubmed ID: 15955451 PavA of Streptococcus Pneumoniae Modulates Adherence, Invasion, and Meningeal Inflammation Infection and Immunity. May, 2005 | Pubmed ID: 15845469 Streptococcus Pneumoniae-induced P38 MAPK-dependent Phosphorylation of RelA at the Interleukin-8 Promotor The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485852 Plasmin(ogen)-binding Alpha-enolase from Streptococcus Pneumoniae: Crystal Structure and Evaluation of Plasmin(ogen)-binding Sites Journal of Molecular Biology. Oct, 2004 | Pubmed ID: 15476816 The Cell Wall Subproteome of Listeria Monocytogenes Proteomics. Oct, 2004 | Pubmed ID: 15378750 Streptococcus Pneumoniae-induced Caspase 6-dependent Apoptosis in Lung Epithelium Infection and Immunity. Sep, 2004 | Pubmed ID: 15321985 Characterization of the Interaction of the Pneumococcal Surface Protein SpsA with the Human Polymeric Immunoglobulin Receptor (hpIgR) The Indian Journal of Medical Research. May, 2004 | Pubmed ID: 15232164 Characterization of Plasmin(ogen) Binding to Streptococcus Pneumoniae The Indian Journal of Medical Research. May, 2004 | Pubmed ID: 15232158 Nucleotide-binding Oligomerization Domain Proteins Are Innate Immune Receptors for Internalized Streptococcus Pneumoniae The Journal of Biological Chemistry. Aug, 2004 | Pubmed ID: 15215247 Dual Roles of PspC, a Surface Protein of Streptococcus Pneumoniae, in Binding Human Secretory IgA and Factor H Journal of Immunology (Baltimore, Md. : 1950). Jul, 2004 | Pubmed ID: 15210807 Binding of Alpha2-macroglobulin to GRAB (Protein G-related Alpha2-macroglobulin-binding Protein), an Important Virulence Factor of Group A Streptococci, is Mediated by Two Charged Motifs in the DeltaA Region The Biochemical Journal. Aug, 2004 | Pubmed ID: 15113281 Glyceraldehyde-3-phosphate Dehydrogenase of Streptococcus Pneumoniae is a Surface-displayed Plasminogen-binding Protein Infection and Immunity. Apr, 2004 | Pubmed ID: 15039372 Ectodomains 3 and 4 of Human Polymeric Immunoglobulin Receptor (hpIgR) Mediate Invasion of Streptococcus Pneumoniae into the Epithelium The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14660617 Identification of a Novel Plasmin(ogen)-binding Motif in Surface Displayed Alpha-enolase of Streptococcus Pneumoniae Molecular Microbiology. Jul, 2003 | Pubmed ID: 12828639 Molecular Cloning of an Alpha-enolase from the Human Filarial Parasite Onchocerca Volvulus That Binds Human Plasminogen Biochimica Et Biophysica Acta. Jun, 2003 | Pubmed ID: 12818429 التالية في الوقت الحقيقي تأثير العوامل الالتهاب الرئوي الحاد الفوعة في نموذج الفأر الالتهاب الرئوي عن طريق البكتيريا للإضاءة الحيوية Malek Saleh1, Mohammed R. Abdullah1, Christian Schulz1, Thomas Kohler1, Thomas Pribyl1, Inga Jensch1, Sven Hammerschmidt1 1Department Genetics of Microorganisms, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald JoVE 51174 면역학 및 감염병학
التالية في الوقت الحقيقي تأثير العوامل الالتهاب الرئوي الحاد الفوعة في نموذج الفأر الالتهاب الرئوي عن طريق البكتيريا للإضاءة الحيوية Malek Saleh1, Mohammed R. Abdullah1, Christian Schulz1, Thomas Kohler1, Thomas Pribyl1, Inga Jensch1, Sven Hammerschmidt1 1Department Genetics of Microorganisms, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald JoVE 51174 면역학 및 감염병학
