Ted J. Hofmann Division of Oncology, Department of Pediatrics Children’s Hospital of Philadelphia Biography Publications Institution JoVE Articles Ted J. Hofmann has not added a biography. If you are Ted J. Hofmann and would like to personalize this page please email our Author Liaison for assistance. Publications Purification of MRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response Human Gene Therapy. Feb, 2019 | Pubmed ID: 30024272 Extracellular Vesicles Released from Mesenchymal Stromal Cells Stimulate Bone Growth in Osteogenesis Imperfecta Cytotherapy. Jan, 2018 | Pubmed ID: 29107738 Monocyte Lineage-derived IL-6 Does Not Affect Chimeric Antigen Receptor T-cell Function Cytotherapy. 07, 2017 | Pubmed ID: 28506444 Hematopoietic Derived Cells Do Not Contribute to Osteogenesis As Osteoblasts Bone. Jan, 2017 | Pubmed ID: 27725318 Dual CD19 and CD123 Targeting Prevents Antigen-loss Relapses After CD19-directed Immunotherapies The Journal of Clinical Investigation. Aug, 2016 | Pubmed ID: 27571406 Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy Cancer Discovery. Dec, 2015 | Pubmed ID: 26516065 Genomic and Functional Comparison of Mesenchymal Stromal Cells Prepared Using Two Isolation Methods Cytotherapy. Mar, 2015 | Pubmed ID: 25659640 Tendon Progenitor Cells in Injured Tendons Have Strong Chondrogenic Potential: the CD105-negative Subpopulation Induces Chondrogenic Degeneration Stem Cells (Dayton, Ohio). Dec, 2014 | Pubmed ID: 25220576 Delayed Marrow Infusion in Mice Enhances Hematopoietic and Osteopoietic Engraftment by Facilitating Transient Expansion of the Osteoblastic Niche Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Nov, 2013 | Pubmed ID: 23916672 IGF-1-mediated Osteoblastic Niche Expansion Enhances Long-term Hematopoietic Stem Cell Engraftment After Murine Bone Marrow Transplantation Stem Cells (Dayton, Ohio). Oct, 2013 | Pubmed ID: 23818291 Megakaryocytes Promote Murine Osteoblastic HSC Niche Expansion and Stem Cell Engraftment After Radioablative Conditioning Blood. Jun, 2013 | Pubmed ID: 23667055 Transplanted Murine Long-term Repopulating Hematopoietic Cells Can Differentiate to Osteoblasts in the Marrow Stem Cell Niche Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2013 | Pubmed ID: 23587920 Improved Isolation and Expansion of Bone Marrow Mesenchymal Stromal Cells Using a Novel Marrow Filter Device Cytotherapy. Feb, 2013 | Pubmed ID: 23321326 Transplanted Bone Marrow Mononuclear Cells and MSCs Impart Clinical Benefit to Children with Osteogenesis Imperfecta Through Different Mechanisms Blood. Aug, 2012 | Pubmed ID: 22829629 Cytokine-induced Osteopoietic Differentiation of Transplanted Marrow Cells Blood. Aug, 2011 | Pubmed ID: 21715305 Osteopoietic Engraftment After Bone Marrow Transplantation: Effect of Inbred Strain of Mice Experimental Hematology. Sep, 2010 | Pubmed ID: 20447443 A Strategy for Single Nucleotide Polymorphism Analysis of Chimerism for Somatic Cell Therapy Cytotherapy. Dec, 2010 | Pubmed ID: 20429790 Restoration and Reversible Expansion of the Osteoblastic Hematopoietic Stem Cell Niche After Marrow Radioablation Blood. Sep, 2009 | Pubmed ID: 19433859 Donor Cell-derived Osteopoiesis Originates from a Self-renewing Stem Cell with a Limited Regenerative Contribution After Transplantation Blood. Apr, 2008 | Pubmed ID: 18182575 Transplantable Marrow Osteoprogenitors Engraft in Discrete Saturable Sites in the Marrow Microenvironment Experimental Hematology. Mar, 2008 | Pubmed ID: 18179857 Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 의학
Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 의학