Tomas Falzone Facultad de Medicina, Departamento de Biología Celular, Histología, Embriología y Genética Universidad de Buenos Aires Biography Publications Institution JoVE Articles Tomas Falzone has not added a biography. If you are Tomas Falzone and would like to personalize this page please email our Author Liaison for assistance. Publications Tau Reduction with Artificial MicroRNAs Modulates Neuronal Physiology and Improves Tauopathy Phenotypes in Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2024 | Pubmed ID: 38310353 Mitochondrial Vulnerability to Oxidation in Human Brain Organoids Modelling Alzheimer's Disease Free Radical Biology & Medicine. Nov, 2023 | Pubmed ID: 37657763 Modeling Alzheimer's Disease Using Human Brain Organoids Methods in Molecular Biology (Clifton, N.J.). 2023 | Pubmed ID: 36399268 DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-derived Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2022 | Pubmed ID: 35803734 Differential Mitochondrial Roles for α-synuclein in DRP1-dependent Fission and PINK1/Parkin-mediated Oxidation Cell Death & Disease. Aug, 2021 | Pubmed ID: 34404758 Kinesin-1-mediated Axonal Transport of CB1 Receptors is Required for Cannabinoid-dependent Axonal Growth and Guidance Development (Cambridge, England). Apr, 2020 | Pubmed ID: 32265198 Neuronal KIF5b Deletion Induces Striatum-dependent Locomotor Impairments and Defects in Membrane Presentation of Dopamine D2 Receptors Journal of Neurochemistry. May, 2019 | Pubmed ID: 30664247 Proteasome Stress Leads to APP Axonal Transport Defects by Promoting Its Amyloidogenic Processing in Lysosomes Journal of Cell Science. Jun, 2018 | Pubmed ID: 29724915 Methods for Quantitative Analysis of Axonal Cargo Transport Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29222784 Mitochondrial Dynamics in Parkinson's Disease: a Role for α-synuclein? Disease Models & Mechanisms. Sep, 2017 | Pubmed ID: 28883016 αSynuclein Control of Mitochondrial Homeostasis in Human-derived Neurons is Disrupted by Mutations Associated with Parkinson's Disease Scientific Reports. Jul, 2017 | Pubmed ID: 28698628 Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2017 | Pubmed ID: 28053030 Hippocampal to Basal Forebrain Transport of Mn is Impaired by Deletion of KLC1, a Subunit of the Conventional Kinesin Microtubule-based Motor NeuroImage. Jan, 2017 | Pubmed ID: 27751944 Mouse Sperm Begin to Undergo Acrosomal Exocytosis in the Upper Isthmus of the Oviduct Developmental Biology. Mar, 2016 | Pubmed ID: 26872876 Fast Axonal Transport of the Proteasome Complex Depends on Membrane Interaction and Molecular Motor Function Journal of Cell Science. Apr, 2014 | Pubmed ID: 24522182 Absence of Dopamine D4 Receptors Results in Enhanced Reactivity to Unconditioned, but Not Conditioned, Fear The European Journal of Neuroscience. Jan, 2002 | Pubmed ID: 11860516 Dopamine D4 Receptor-deficient Mice Display Cortical Hyperexcitability The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2001 | Pubmed ID: 11356863 Authentic Cell-specific and Developmentally Regulated Expression of Pro-opiomelanocortin Genomic Fragments in Hypothalamic and Hindbrain Neurons of Transgenic Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 1998 | Pubmed ID: 9712635 Author Spotlight: Optimizing the Neurovascular Development of Human Brain Organoid in Chick Embryo Luciano Fiore1,2, Jan Arderiu3, Andrea Martí-Sarrias3,4, Isabel Turpín3,4, Ruth I. Pareja3,5, Arcadi Navarro5,6,7,8, Mariana Holubiec2,9, Julieta Bianchelli9, Tomas Falzone2,9, Gonzalo Spelzini1,2, Gabriel Scicolone1,2, Sandra Acosta3,4 1Instituto de Biología Celular y Neurociencias “Prof. E. De Robertis” (IBCN), CONICET - Universidad de Buenos Aires, 2Facultad de Medicina, Departamento de Biología Celular, Histología, Embriología y Genética, Universidad de Buenos Aires, 3Institute of Neurosciences, Pathology and Experimental Therapeutics Dept, University of Barcelona, 4Functional Neurogenomics Group, Neurodevelopmental Disorders, IDIBELL, L’Hospitalet de Llobregat, 5IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 6Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, 7Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 8BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation, 9Instituto de Investigación en Biomedicina (IBioBA) – CONICET – Instituto Partner de la Sociedad Max Planck JoVE 65710 발생학
Author Spotlight: Optimizing the Neurovascular Development of Human Brain Organoid in Chick Embryo Luciano Fiore1,2, Jan Arderiu3, Andrea Martí-Sarrias3,4, Isabel Turpín3,4, Ruth I. Pareja3,5, Arcadi Navarro5,6,7,8, Mariana Holubiec2,9, Julieta Bianchelli9, Tomas Falzone2,9, Gonzalo Spelzini1,2, Gabriel Scicolone1,2, Sandra Acosta3,4 1Instituto de Biología Celular y Neurociencias “Prof. E. De Robertis” (IBCN), CONICET - Universidad de Buenos Aires, 2Facultad de Medicina, Departamento de Biología Celular, Histología, Embriología y Genética, Universidad de Buenos Aires, 3Institute of Neurosciences, Pathology and Experimental Therapeutics Dept, University of Barcelona, 4Functional Neurogenomics Group, Neurodevelopmental Disorders, IDIBELL, L’Hospitalet de Llobregat, 5IBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, 6Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, 7Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 8BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation, 9Instituto de Investigación en Biomedicina (IBioBA) – CONICET – Instituto Partner de la Sociedad Max Planck JoVE 65710 발생학