Vincent Poitout Montreal Diabetes Research Center CRCHUM Biography Publications Institution JoVE Articles Vincent Poitout has not added a biography. If you are Vincent Poitout and would like to personalize this page please email our Author Liaison for assistance. Publications Per-Arnt-Sim Kinase Regulates Pancreatic Duodenal Homeobox-1 Protein Stability Via Phosphorylation of Glycogen Synthase Kinase 3 Beta in Pancreatic Beta Cells The Journal of Biological Chemistry. Jul, 2013 | Pubmed ID: 23853095 Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells Diabetes. Aug, 2013 | Pubmed ID: 23656887 The Fatty Acid Receptor FFA1/GPR40 a Decade Later: How Much Do We Know? Trends in Endocrinology and Metabolism: TEM. Aug, 2013 | Pubmed ID: 23631851 Fatty Acid Receptor Gpr40 Mediates Neuromicrovascular Degeneration Induced by Transarachidonic Acids in Rodents Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2013 | Pubmed ID: 23520164 Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats Diabetes. Jun, 2013 | Pubmed ID: 23378607 The Free Fatty Acid Receptor G Protein-coupled Receptor 40 (GPR40) Protects from Bone Loss Through Inhibition of Osteoclast Differentiation The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23335512 Discovery of Novel Glucose-regulated Proteins in Isolated Human Pancreatic Islets Using LC-MS/MS-based Proteomics Journal of Proteome Research. Jul, 2012 | Pubmed ID: 22578083 Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans Via Toll-Like Receptor-4 and NF-κB Signalling PloS One. 2012 | Pubmed ID: 22558381 Glucose Activates Free Fatty Acid Receptor 1 Gene Transcription Via Phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of Pancreas-duodenum Homeobox-1 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308370 Menschliche Mutation Im Pro-Arnt-Sim (PAS)-Gebietsenthalten-Proteinkinase (PASK) Bewirkt, Dass Basal-Insulin-Hypersekretion The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22065581 Binding of Activating Transcription Factor 6 to the A5/Core of the Rat Insulin II Gene Promoter Does Not Mediate Its Transcriptional Repression Journal of Molecular Endocrinology. Dec, 2011 | Pubmed ID: 21821716 Lack of Preservation of Insulin Gene Expression by a Glucagon-like Peptide 1 Agonist or a Dipeptidyl Peptidase 4 Inhibitor in an in Vivo Model of Glucolipotoxicity Diabetes Research and Clinical Practice. Mar, 2010 | Pubmed ID: 20092903 Lack of TXNIP Protects Against Mitochondria-mediated Apoptosis but Not Against Fatty Acid-induced ER Stress-mediated Beta-cell Death Diabetes. Feb, 2010 | Pubmed ID: 19875615 Glucolipotoxicity of the Pancreatic Beta Cell Biochimica Et Biophysica Acta. Mar, 2010 | Pubmed ID: 19715772 Cystic Fibrosis-related Diabetes: from CFTR Dysfunction to Oxidative Stress The Clinical Biochemist. Reviews / Australian Association of Clinical Biochemists. Nov, 2009 | Pubmed ID: 20011209 Deletion of GPR40 Impairs Glucose-induced Insulin Secretion in Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets Diabetes. Nov, 2009 | Pubmed ID: 19720802 Involvement of Per-Arnt-Sim Kinase and Extracellular-regulated Kinases-1/2 in Palmitate Inhibition of Insulin Gene Expression in Pancreatic Beta-cells Diabetes. Sep, 2009 | Pubmed ID: 19502418 Pioglitazone Acutely Reduces Insulin Secretion and Causes Metabolic Deceleration of the Pancreatic Beta-cell at Submaximal Glucose Concentrations Endocrinology. Aug, 2009 | Pubmed ID: 19406947 GPR40: Good Cop, Bad Cop? Diabetes. May, 2009 | Pubmed ID: 19401432 Adipose Triglyceride Lipase is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion The Journal of Biological Chemistry. Jun, 2009 | Pubmed ID: 19389712 The Stability and Transactivation Potential of the Mammalian MafA Transcription Factor Are Regulated by Serine 65 Phosphorylation The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19004825 Glucolipotoxicity of the Pancreatic Beta-cell: Myth or Reality? Biochemical Society Transactions. Oct, 2008 | Pubmed ID: 18793158 The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion in Vivo After High-fat Feeding Diabetes. Sep, 2008 | Pubmed ID: 18559658 Glucolipotoxicity: Fuel Excess and Beta-cell Dysfunction Endocrine Reviews. May, 2008 | Pubmed ID: 18048763 Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets Diabetes. Feb, 2008 | Pubmed ID: 17991758 Phospholipid Hydrolysis and Insulin Secretion: a Step Toward Solving the Rubik's Cube American Journal of Physiology. Endocrinology and Metabolism. Feb, 2008 | Pubmed ID: 17925452 G Protein-coupled Receptors and Insulin Secretion: 119 and Counting Endocrinology. Jun, 2007 | Pubmed ID: 17507578 GPR40 is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion in Vivo Diabetes. Apr, 2007 | Pubmed ID: 17395749 Characterization of the Human Pancreatic Islet Proteome by Two-dimensional LC/MS/MS Journal of Proteome Research. Dec, 2006 | Pubmed ID: 17137336 Regulation of the Insulin Gene by Glucose and Fatty Acids The Journal of Nutrition. Apr, 2006 | Pubmed ID: 16549443 Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 15944145 Pancreatic Islet Response to Hyperglycemia is Dependent on Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) FEBS Letters. Apr, 2005 | Pubmed ID: 15848159 The Islet Beta Cell-enriched MafA Activator is a Key Regulator of Insulin Gene Transcription The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15665000 Elevated Glucose Attenuates Human Insulin Gene Promoter Activity in INS-1 Pancreatic Beta-cells Via Reduced Nuclear Factor Binding to the A5/core and Z Element Molecular Endocrinology (Baltimore, Md.). May, 2005 | Pubmed ID: 15650027 Evidence Against the Involvement of Oxidative Stress in Fatty Acid Inhibition of Insulin Secretion Diabetes. Oct, 2004 | Pubmed ID: 15448091 Beta-cell Lipotoxicity: Burning Fat into Heat? Endocrinology. Aug, 2004 | Pubmed ID: 15265823 A Role for the Malonyl-CoA/long-chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli Diabetes. Apr, 2004 | Pubmed ID: 15047616 Beta-cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes Diabetes. Feb, 2004 | Pubmed ID: 14749276 The Ins and Outs of Fatty Acids on the Pancreatic Beta Cell Trends in Endocrinology and Metabolism: TEM. Jul, 2003 | Pubmed ID: 12826323 Palmitate Inhibition of Insulin Gene Expression is Mediated at the Transcriptional Level Via Ceramide Synthesis The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12771145 Insulinsekretorischen Mangel Und Glucose-Intoleranz in Rab3A Null Mäusen The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12510060 Effect of the Two-layer (University of Wisconsin Solution-perfluorochemical Plus O2) Method of Pancreas Preservation on Human Islet Isolation, As Assessed by the Edmonton Isolation Protocol Transplantation. Nov, 2002 | Pubmed ID: 12451242 Increasing Triglyceride Synthesis Inhibits Glucose-induced Insulin Secretion in Isolated Rat Islets of Langerhans: a Study Using Adenoviral Expression of Diacylglycerol Acyltransferase Endocrinology. Sep, 2002 | Pubmed ID: 12193544 Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans from Hyperglycemic Versus Normoglycemic Rats Diabetes. Mar, 2002 | Pubmed ID: 11872664 Minireview: Secondary Beta-cell Failure in Type 2 Diabetes--a Convergence of Glucotoxicity and Lipotoxicity Endocrinology. Feb, 2002 | Pubmed ID: 11796484 Ein Modell der chronischen Nährstoff Infusion in der Ratte Grace Fergusson1, Mélanie Ethier1, Bader Zarrouki1,2, Ghislaine Fontés1, Vincent Poitout1,2 1Montreal Diabetes Research Center, CRCHUM, 2Department of Medicine, University of Montreal JoVE 50267 의학
Ein Modell der chronischen Nährstoff Infusion in der Ratte Grace Fergusson1, Mélanie Ethier1, Bader Zarrouki1,2, Ghislaine Fontés1, Vincent Poitout1,2 1Montreal Diabetes Research Center, CRCHUM, 2Department of Medicine, University of Montreal JoVE 50267 의학