Wade G. Regehr Department Name Harvard Medical School Biography Publications Institution JoVE Articles Wade G. Regehr has not added a biography. If you are Wade G. Regehr and would like to personalize this page please email our Author Liaison for assistance. Publications Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release Neuron. Feb, 2019 | Pubmed ID: 30733150 Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells Neuron. Nov, 2018 | Pubmed ID: 30293822 Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2018 | Pubmed ID: 29593071 Silk Fibroin Films Facilitate Single-Step Targeted Expression of Optogenetic Proteins Cell Reports. Mar, 2018 | Pubmed ID: 29562189 Synaptotagmin 7 Confers Frequency Invariance Onto Specialized Depressing Synapses Nature. 11, 2017 | Pubmed ID: 29088700 The Mechanisms and Functions of Synaptic Facilitation Neuron. May, 2017 | Pubmed ID: 28472650 The Readily Releasable Pool of Synaptic Vesicles Current Opinion in Neurobiology. 04, 2017 | Pubmed ID: 28103533 Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex Cell Reports. 12, 2016 | Pubmed ID: 28009294 Purkinje Cells Directly Inhibit Granule Cells in Specialized Regions of the Cerebellar Cortex Neuron. Sep, 2016 | Pubmed ID: 27593180 Purkinje Cell Collaterals Enable Output Signals from the Cerebellar Cortex to Feed Back to Purkinje Cells and Interneurons Neuron. 07, 2016 | Pubmed ID: 27346533 Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 06, 2016 | Pubmed ID: 27307229 Determining Synaptic Parameters Using High-frequency Activation Journal of Neuroscience Methods. May, 2016 | Pubmed ID: 26972952 The Calcium Sensor Synaptotagmin 7 is Required for Synaptic Facilitation Nature. Jan, 2016 | Pubmed ID: 26738595 Active Dendrites and Differential Distribution of Calcium Channels Enable Functional Compartmentalization of Golgi Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2015 | Pubmed ID: 26609148 Cell Type-specific Manipulation with GFP-dependent Cre Recombinase Nature Neuroscience. Sep, 2015 | Pubmed ID: 26258682 Protein Kinase C is a Calcium Sensor for Presynaptic Short-term Plasticity ELife. Aug, 2014 | Pubmed ID: 25097249 Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain Neuron. Jul, 2014 | Pubmed ID: 24991957 The Substantia Nigra Conveys Target-dependent Excitatory and Inhibitory Outputs from the Basal Ganglia to the Thalamus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2014 | Pubmed ID: 24899724 Achieving High-frequency Optical Control of Synaptic Transmission The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24872574 Calcium-dependent PKC Isoforms Have Specialized Roles in Short-term Synaptic Plasticity Neuron. May, 2014 | Pubmed ID: 24794094 Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release Annual Review of Physiology. Month, 2014 | Pubmed ID: 24274737 Normalization of Input Patterns in an Associative Network Journal of Neurophysiology. Feb, 2014 | Pubmed ID: 24225543 Hyperpolarization Induces a Long-term Increase in the Spontaneous Firing Rate of Cerebellar Golgi Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2013 | Pubmed ID: 23554471 Presynaptic Calcium Influx Controls Neurotransmitter Release in Part by Regulating the Effective Size of the Readily Releasable Pool The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2013 | Pubmed ID: 23486937 Metabotropic Glutamate Receptors Drive Global Persistent Inhibition in the Visual Thalamus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013 | Pubmed ID: 23392677 Calcium-dependent Isoforms of Protein Kinase C Mediate Glycine-induced Synaptic Enhancement at the Calyx of Held The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2012 | Pubmed ID: 23035091 Adaptive Regulation Maintains Posttetanic Potentiation at Cerebellar Granule Cell Synapses in the Absence of Calcium-dependent PKC The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2012 | Pubmed ID: 22993418 Autistic-like Behaviour and Cerebellar Dysfunction in Purkinje Cell Tsc1 Mutant Mice Nature. Aug, 2012 | Pubmed ID: 22763451 Short-term Presynaptic Plasticity Cold Spring Harbor Perspectives in Biology. Jul, 2012 | Pubmed ID: 22751149 Identification of an Inhibitory Circuit That Regulates Cerebellar Golgi Cell Activity Neuron. Jan, 2012 | Pubmed ID: 22243753 Calcium-dependent Isoforms of Protein Kinase C Mediate Posttetanic Potentiation at the Calyx of Held Neuron. Jun, 2011 | Pubmed ID: 21658591 Calcium Microdomains Near R-type Calcium Channels Control the Induction of Presynaptic Long-term Potentiation at Parallel Fiber to Purkinje Cell Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2011 | Pubmed ID: 21471358 Short-term Forms of Presynaptic Plasticity Current Opinion in Neurobiology. Apr, 2011 | Pubmed ID: 21353526 Presynaptic CB1 Receptors Regulate Synaptic Plasticity at Cerebellar Parallel Fiber Synapses Journal of Neurophysiology. Feb, 2011 | Pubmed ID: 21084685 Cholinergic Activation of M2 Receptors Leads to Context-dependent Modulation of Feedforward Inhibition in the Visual Thalamus PLoS Biology. Apr, 2010 | Pubmed ID: 20386723 Identification of the Synthetic Pathway Producing the Endocannabinoid That Mediates the Bulk of Retrograde Signaling in the Brain Neuron. Feb, 2010 | Pubmed ID: 20159441 Dynamics of Fast and Slow Inhibition from Cerebellar Golgi Cells Allow Flexible Control of Synaptic Integration Neuron. Sep, 2009 | Pubmed ID: 19778512 Linking Genetically Defined Neurons to Behavior Through a Broadly Applicable Silencing Allele Neuron. Aug, 2009 | Pubmed ID: 19679071 Activity-dependent Regulation of Synapses by Retrograde Messengers Neuron. Jul, 2009 | Pubmed ID: 19640475 Somatic Spikes Regulate Dendritic Signaling in Small Neurons in the Absence of Backpropagating Action Potentials The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2009 | Pubmed ID: 19535592 Inhibitory Regulation of Electrically Coupled Neurons in the Inferior Olive is Mediated by Asynchronous Release of GABA Neuron. May, 2009 | Pubmed ID: 19477156 Noradrenergic Control of Associative Synaptic Plasticity by Selective Modulation of Instructive Signals Neuron. Apr, 2009 | Pubmed ID: 19376071 Serotonin Evokes Endocannabinoid Release and Retrogradely Suppresses Excitatory Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18562622 Active Dendritic Conductances Dynamically Regulate GABA Release from Thalamic Interneurons Neuron. Feb, 2008 | Pubmed ID: 18255034 Timing Dependence of the Induction of Cerebellar LTD Neuropharmacology. Jan, 2008 | Pubmed ID: 17669443 Reliability and Heterogeneity of Calcium Signaling at Single Presynaptic Boutons of Cerebellar Granule Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2007 | Pubmed ID: 17652580 Differential Expression of Posttetanic Potentiation and Retrograde Signaling Mediate Target-dependent Short-term Synaptic Plasticity Neuron. Jun, 2007 | Pubmed ID: 17582334 Fast Vesicle Replenishment and Rapid Recovery from Desensitization at a Single Synaptic Release Site The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17507567 Local Interneurons Regulate Synaptic Strength by Retrograde Release of Endocannabinoids The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2006 | Pubmed ID: 17005857 Retrograde Endocannabinoid Signaling in the Cerebellar Cortex Cerebellum (London, England). Month, 2006 | Pubmed ID: 16818388 Brief Bursts of Parallel Fiber Activity Trigger Calcium Signals in Bergmann Glia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16807325 Sustained Elevation of Dendritic Calcium Evokes Widespread Endocannabinoid Release and Suppression of Synapses Onto Cerebellar Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16793891 The Influence of Multivesicular Release and Postsynaptic Receptor Saturation on Transmission at Granule Cell to Purkinje Cell Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2005 | Pubmed ID: 16354924 Endocannabinoids Control the Induction of Cerebellar LTD Neuron. Nov, 2005 | Pubmed ID: 16301180 Conventional Synapses for Unconventional Cells Neuron. Jun, 2005 | Pubmed ID: 15924854 Timing and Specificity of Feed-forward Inhibition Within the LGN Neuron. Mar, 2005 | Pubmed ID: 15797552 Associative Short-term Synaptic Plasticity Mediated by Endocannabinoids Neuron. Feb, 2005 | Pubmed ID: 15694328 Short-term Synaptic Plasticity: a Comparison of Two Synapses Nature Reviews. Neuroscience. Aug, 2004 | Pubmed ID: 15263893 Variance-mean Analysis in the Presence of a Rapid Antagonist Indicates Vesicle Depletion Underlies Depression at the Climbing Fiber Synapse Neuron. Jul, 2004 | Pubmed ID: 15233922 Presynaptic Calcium Measurements at Physiological Temperatures Using a New Class of Dextran-conjugated Indicators Journal of Neurophysiology. Jul, 2004 | Pubmed ID: 15212445 Endocannabinoids Inhibit Transmission at Granule Cell to Purkinje Cell Synapses by Modulating Three Types of Presynaptic Calcium Channels The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15201335 Structural Contributions to Short-term Synaptic Plasticity Physiological Reviews. Jan, 2004 | Pubmed ID: 14715911 Retinogeniculate Synaptic Properties Controlling Spike Number and Timing in Relay Neurons Journal of Neurophysiology. Oct, 2003 | Pubmed ID: 14534270 Brief Presynaptic Bursts Evoke Synapse-specific Retrograde Inhibition Mediated by Endogenous Cannabinoids Nature Neuroscience. Oct, 2003 | Pubmed ID: 14502290 "Resistant" Channels Reluctantly Reveal Their Roles Neuron. Jul, 2003 | Pubmed ID: 12895414 Calcium Dependence of Retrograde Inhibition by Endocannabinoids at Synapses Onto Purkinje Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12867523 Presynaptic Modulation of the Retinogeniculate Synapse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2003 | Pubmed ID: 12716920 Ultrastructural Contributions to Desensitization at Cerebellar Mossy Fiber to Granule Cell Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2003 | Pubmed ID: 12657677 Interaction of Postsynaptic Receptor Saturation with Presynaptic Mechanisms Produces a Reliable Synapse Neuron. Dec, 2002 | Pubmed ID: 12495626 Quantal Events Shape Cerebellar Interneuron Firing Nature Neuroscience. Dec, 2002 | Pubmed ID: 12411959 Inhibition of Interneuron Firing Extends the Spread of Endocannabinoid Signaling in the Cerebellum Neuron. May, 2002 | Pubmed ID: 12062024 Retrograde Signaling by Endocannabinoids Current Opinion in Neurobiology. Jun, 2002 | Pubmed ID: 12049940 Contributions of Receptor Desensitization and Saturation to Plasticity at the Retinogeniculate Synapse Neuron. Feb, 2002 | Pubmed ID: 11879654 Assessing the Role of Calcium-induced Calcium Release in Short-term Presynaptic Plasticity at Excitatory Central Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756484 Vivo Optogenetic proteinlerin ipek/AAV filmleri kullanarak hedeflenen ifade Skyler L. Jackman1, Christopher H. Chen2, Wade G. Regehr2 1Vollum Institute, Oregon Health and Science University, 2Harvard Medical School JoVE 58728 신경과학
Vivo Optogenetic proteinlerin ipek/AAV filmleri kullanarak hedeflenen ifade Skyler L. Jackman1, Christopher H. Chen2, Wade G. Regehr2 1Vollum Institute, Oregon Health and Science University, 2Harvard Medical School JoVE 58728 신경과학