Wayne Mitzner Bloomberg School of Public Health, Environmental Health Sciences Johns Hopkins University Biography Publications Institution JoVE Articles Wayne Mitzner has not added a biography. If you are Wayne Mitzner and would like to personalize this page please email our Author Liaison for assistance. Publications Experimental Progressive Emphysema in BALB/cJ Mice As a Model for Chronic Alveolar Destruction In Humans American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2015 | Pubmed ID: 26232300 Aberrant DNA Methylation of Phosphodiesterase 4D: Effect on Airway Smooth Muscle Cell Phenotypes American Journal of Respiratory Cell and Molecular Biology. Jul, 2015 | Pubmed ID: 26181301 Transgenically-expressed Secretoglobin 3A2 Accelerates Resolution of Bleomycin-induced Pulmonary Fibrosis in Mice BMC Pulmonary Medicine. 2015 | Pubmed ID: 26178733 Lung Density Changes with Growth and Inflation Chest. May, 2015 | Pubmed ID: 25996948 Telomere Dysfunction Causes Alveolar Stem Cell Failure Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25840590 Angiogenesis and Airway Reactivity in Asthmatic Brown Norway Rats Angiogenesis. Jan, 2015 | Pubmed ID: 25149641 Effect of Point Sampling Density in Quantifying Mouse Lung Emphysema Anatomical Record (Hoboken, N.J. : 2007). Nov, 2014 | Pubmed ID: 25371008 A Mouse Model of Chronic Idiopathic Pulmonary Fibrosis Physiological Reports. Feb, 2014 | Pubmed ID: 24744912 Pulmonary Delivery of Docosahexaenoic Acid Mitigates Bleomycin-induced Pulmonary Fibrosis BMC Pulmonary Medicine. 2014 | Pubmed ID: 24742272 Macrophage Migration Inhibitory Factor is a Novel Determinant of Cigarette Smoke-induced Lung Damage American Journal of Respiratory Cell and Molecular Biology. Jul, 2014 | Pubmed ID: 24490973 Alterations of the Lung Methylome in Allergic Airway Hyper-responsiveness Environmental and Molecular Mutagenesis. Apr, 2014 | Pubmed ID: 24446183 Effects of Lung Inflation on Airway Heterogeneity During Histaminergic Bronchoconstriction Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2013 | Pubmed ID: 23813528 Epigenetic Alterations by DNA Methylation in House Dust Mite-induced Airway Hyperresponsiveness American Journal of Respiratory Cell and Molecular Biology. Aug, 2013 | Pubmed ID: 23526225 TLR3 Deficiency Induces Chronic Inflammatory Cardiomyopathy in Resistant Mice Following Coxsackievirus B3 Infection: Role for IL-4 American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2013 | Pubmed ID: 23255589 Airway-parenchymal Interdependence Comprehensive Physiology. Jul, 2012 | Pubmed ID: 23723029 Last Word on Viewpoint: Unresolved Mysteries Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2012 | Pubmed ID: 23243297 In Memoriam Dr Solbert Permutt, 1925–2012 The European Respiratory Journal : Official Journal of the European Society for Clinical Respiratory Physiology. Oct, 2012 | Pubmed ID: 23193573 The Effects of Age and Carbon Black on Airway Resistance in Mice Inhalation Toxicology. Dec, 2012 | Pubmed ID: 23150990 Variation in Airway Responsiveness of Male C57BL/6 Mice from 5 Vendors Journal of the American Association for Laboratory Animal Science : JAALAS. Jul, 2012 | Pubmed ID: 23043804 Last Word on Counterpoint: Alterations in Airway Smooth Muscle Phenotype Do Not Cause Airway Hyperresponsiveness in Asthma Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2012 | Pubmed ID: 22942225 Counterpoint: Alterations in Airway Smooth Muscle Phenotype Do Not Cause Airway Hyperresponsiveness in Asthma Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2012 | Pubmed ID: 22942220 Viewpoint: Unresolved Mysteries Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2012 | Pubmed ID: 22797308 IL-33 Independently Induces Eosinophilic Pericarditis and Cardiac Dilation: ST2 Improves Cardiac Function Circulation. Heart Failure. May, 2012 | Pubmed ID: 22454393 Testosterone and Interleukin-1β Increase Cardiac Remodeling During Coxsackievirus B3 Myocarditis Via Serpin A 3n American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2012 | Pubmed ID: 22328081 Targeted Deletion of Jun/AP-1 in Alveolar Epithelial Cells Causes Progressive Emphysema and Worsens Cigarette Smoke-induced Lung Inflammation The American Journal of Pathology. Feb, 2012 | Pubmed ID: 22265050 Angiotensin Receptor Blockade Attenuates Cigarette Smoke-induced Lung Injury and Rescues Lung Architecture in Mice The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22182843 Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 Versus TRIF in Progression to Chronic Disease Clinical & Developmental Immunology. 2012 | Pubmed ID: 22013485 Mechanics of the Lung in the 20th Century Comprehensive Physiology. Oct, 2011 | Pubmed ID: 23733695 Useful Models of Asthma Need to Properly Phenotype Airway Narrowing American Journal of Respiratory Cell and Molecular Biology. Dec, 2011 | Pubmed ID: 22140201 Emphysema--a Disease of Small Airways or Lung Parenchyma? The New England Journal of Medicine. Oct, 2011 | Pubmed ID: 22029986 Telomere Length is a Determinant of Emphysema Susceptibility American Journal of Respiratory and Critical Care Medicine. Oct, 2011 | Pubmed ID: 21757622 Exposure to Neonatal Cigarette Smoke Causes Durable Lung Changes but Does Not Potentiate Cigarette Smoke-induced Chronic Obstructive Pulmonary Disease in Adult Mice Experimental Lung Research. Aug, 2011 | Pubmed ID: 21649527 Individual Canine Airway Response Variability to a Deep Inspiration Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine. 2011 | Pubmed ID: 21487453 Application of Carbon Monoxide Diffusing Capacity in the Mouse Lung Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2011 | Pubmed ID: 21310888 Neonatal Hyperoxia Contributes Additively to Cigarette Smoke-induced Chronic Obstructive Pulmonary Disease Changes in Adult Mice American Journal of Respiratory Cell and Molecular Biology. Sep, 2011 | Pubmed ID: 21239606 Lung and Vascular Function During Chronic Severe Pulmonary Ischemia Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2011 | Pubmed ID: 21148340 Chronic Intermittent Hypoxia Induces Lung Growth in Adult Mice American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2011 | Pubmed ID: 21131398 A Theoretical Model of the Application of RF Energy to the Airway Wall and Its Experimental Validation Biomedical Engineering Online. 2010 | Pubmed ID: 21110893 Effect of Parenchymal Stiffness on Canine Airway Size with Lung Inflation PloS One. 2010 | Pubmed ID: 20436667 Standards for Quantitative Assessment of Lung Structure Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2010 | Pubmed ID: 20395546 Animal Models of Airway Inflammation and Airway Smooth Muscle Remodelling in Asthma Pulmonary Pharmacology & Therapeutics. Oct, 2009 | Pubmed ID: 19393759 Cell Stiffness, Contractile Stress and the Role of Extracellular Matrix Biochemical and Biophysical Research Communications. May, 2009 | Pubmed ID: 19327344 An Improved Simple Method of Mouse Lung Intubation Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2009 | Pubmed ID: 19150857 Lack of Antibody Affinity Maturation Due to Poor Toll-like Receptor Stimulation Leads to Enhanced Respiratory Syncytial Virus Disease Nature Medicine. Jan, 2009 | Pubmed ID: 19079256 Assessment of Heterogeneous Airway Constriction in Dogs: a Structure-function Analysis Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2009 | Pubmed ID: 18927269 Selective Expression Rather Than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2008 | Pubmed ID: 18941202 Behavioral and Respiratory Characteristics During Sleep in Neonatal DBA/2J and A/J Mice Brain Research. Nov, 2008 | Pubmed ID: 18817755 Use of Mean Airspace Chord Length to Assess Emphysema Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2008 | Pubmed ID: 18719230 Anisotropic Nature of Mouse Lung Parenchyma Annals of Biomedical Engineering. Dec, 2008 | Pubmed ID: 18633711 Why Can't Mice Just Learn to Pant? Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2008 | Pubmed ID: 18535131 Effect of Severe Calorie Restriction on the Lung in Two Strains of Mice American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2008 | Pubmed ID: 18515406 Effects of Leptin Deficiency on Postnatal Lung Development in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2008 | Pubmed ID: 18467551 Exposure to Inhaled Particulate Matter Impairs Cardiac Function in Senescent Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2008 | Pubmed ID: 18448608 A Further Comment on Point:Counterpoint "Airway Smooth Muscle Is/is Not Useful" Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2008 | Pubmed ID: 18326879 Temporal Variability in the Responses of Individual Canine Airways to Methacholine Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2008 | Pubmed ID: 18309091 Different Mechanisms of Atelectasis Formation Require Different Treatment Strategies Experimental Lung Research. Mar, 2008 | Pubmed ID: 18307121 Effect of Bronchial Thermoplasty on Airway Closure Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine. Oct, 2007 | Pubmed ID: 19865588 Sex Differences in Mouse Models of Asthma Canadian Journal of Physiology and Pharmacology. Dec, 2007 | Pubmed ID: 18066124 Counterpoint: Lung Impedance Measurements Are Not More Useful Than Simpler Measurements of Lung Function in Animal Models of Pulmonary Disease Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2007 | Pubmed ID: 17965240 Genetic and Pharmacologic Evidence Links Oxidative Stress to Ventilator-induced Lung Injury in Mice American Journal of Respiratory and Critical Care Medicine. Dec, 2007 | Pubmed ID: 17901416 Invasive and Noninvasive Methods for Studying Pulmonary Function in Mice Respiratory Research. 2007 | Pubmed ID: 17868442 Global Expression Profiles from C57BL/6J and DBA/2J Mouse Lungs to Determine Aging-related Genes Physiological Genomics. Nov, 2007 | Pubmed ID: 17726092 Airway Responsiveness Should Be a Measurement of the Responsiveness of Airways American Journal of Respiratory and Critical Care Medicine. Jul, 2007 | Pubmed ID: 17617536 Comments on Point: Counterpoint: "airway Smooth Muscle Is/is Not Useful" Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2007 | Pubmed ID: 17469217 Effects of Pulmonary Ischemia on Lung Morphology American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2007 | Pubmed ID: 17449796 Variation in Senescent-dependent Lung Changes in Inbred Mouse Strains Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2007 | Pubmed ID: 17218422 Interpreting Lung Functional Changes American Journal of Respiratory and Critical Care Medicine. Jan, 2007 | Pubmed ID: 17179498 PEEP-induced Changes in Epithelial Permeability in Inbred Mouse Strains Respiratory Physiology & Neurobiology. Jun, 2007 | Pubmed ID: 17134945 Evaluation of Emphysema Severity and Progression in a Rabbit Model: Comparison of Hyperpolarized 3He and 129Xe Diffusion MRI with Lung Morphometry Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2007 | Pubmed ID: 17110518 C5 Modulates Airway Hyperreactivity and Pulmonary Eosinophilia During Enhanced Respiratory Syncytial Virus Disease by Decreasing C3a Receptor Expression Journal of Virology. Jan, 2007 | Pubmed ID: 17079327 Age-dependent Changes of Airway and Lung Parenchyma in C57BL/6J Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2007 | Pubmed ID: 16946023 The Classical Guyton View That Mean Systemic Pressure, Right Atrial Pressure, and Venous Resistance Govern Venous Return Is/is Not Correct Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2006 | Pubmed ID: 17094188 Bronchial Thermoplasty in Asthma Allergology International : Official Journal of the Japanese Society of Allergology. Sep, 2006 | Pubmed ID: 17075262 Comments on Point:Counterpoint Series "Active Venoconstriction Is/is Not Important in Maintaining or Raising End-diastolic Volume and Stoke Volume During Exercise and Orthostasis." Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2006 | Pubmed ID: 16973821 Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2006 | Pubmed ID: 16741256 Morphologic Quantification of Heterogeneous Parenchyma Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2006 | Pubmed ID: 16646137 Comparison of Postnatal Lung Growth and Development Between C3H/HeJ and C57BL/6J Mice Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2006 | Pubmed ID: 16282432 Pulmonary Ischemia Induces Lung Remodeling and Angiogenesis Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2006 | Pubmed ID: 16210444 Heritable and Pharmacological Influences on Pauses and Apneas in Inbred Mice During Anesthesia and Emergence Experimental Lung Research. Nov-Dec, 2005 | Pubmed ID: 16684716 Invasive Versus Noninvasive Measurement of Allergic and Cholinergic Airway Responsiveness in Mice Respiratory Research. 2005 | Pubmed ID: 16309547 Disruption of Nrf2 Enhances Susceptibility to Severe Airway Inflammation and Asthma in Mice The Journal of Experimental Medicine. Jul, 2005 | Pubmed ID: 15998787 Effects of Tidal Volume and Respiratory Frequency on Lung Lymph Flow Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2005 | Pubmed ID: 15790690 In Vivo Evaluation of the Effectiveness of Bronchial Thermoplasty with Computed Tomography Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2005 | Pubmed ID: 15718404 Stresses on Pulmonary Blood Vessels American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2005 | Pubmed ID: 15591038 On the Terminology for Describing the Length-force Relationship and Its Changes in Airway Smooth Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2004 | Pubmed ID: 15531570 Vascular Remodeling in the Circulations of the Lung Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2004 | Pubmed ID: 15475558 The Effect of Leptin on the Ventilatory Responseto Hyperoxia Experimental Lung Research. Oct-Nov, 2004 | Pubmed ID: 15371092 The Use and Misuse of Penh in Animal Models of Lung Disease American Journal of Respiratory Cell and Molecular Biology. Sep, 2004 | Pubmed ID: 15317683 Differences in Alveolar Size in Inbred Mouse Strains Respiratory Physiology & Neurobiology. Jun, 2004 | Pubmed ID: 15186789 Repetitive Measurements of Pulmonary Mechanics to Inhaled Cholinergic Challenge in Spontaneously Breathing Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2004 | Pubmed ID: 15121749 On Defining Total Lung Capacity in the Mouse Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2004 | Pubmed ID: 15075308 Dynamic Regulation of Alveolar Morphogenesis in Mature Lungs American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2004 | Pubmed ID: 15064236 Airway Smooth Muscle: the Appendix of the Lung American Journal of Respiratory and Critical Care Medicine. Apr, 2004 | Pubmed ID: 14742304 Effects of the Alpha2-adrenoceptor Agonist Dexmedetomidine on Bronchoconstriction in Dogs Anesthesiology. Feb, 2004 | Pubmed ID: 14739811 The Effect of Neonatal Hyperoxia on the Lung of P21Waf1/Cip1/Sdi1-deficient Mice American Journal of Respiratory Cell and Molecular Biology. May, 2004 | Pubmed ID: 14607813 Airway Distension with Lung Inflation Measured by HRCT Academic Radiology. Oct, 2003 | Pubmed ID: 14587628 Effects of Tamoxifen on Ischemia-induced Angiogenesis in the Mouse Lung Angiogenesis. 2003 | Pubmed ID: 14517406 Functional Imaging of Airway Narrowing Respiratory Physiology & Neurobiology. Sep, 2003 | Pubmed ID: 14516735 Understanding Airway Pathophysiology with Computed Tomograpy Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2003 | Pubmed ID: 12851424 Changes in Lung Permeability and Lung Mechanics Accompany Homeostatic Instability in Senescent Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Oct, 2003 | Pubmed ID: 12794030 Duration of Deep Inspiration and Subsequent Airway Constriction in Vivo The Journal of Asthma : Official Journal of the Association for the Care of Asthma. Apr, 2003 | Pubmed ID: 12765312 Identification of Genes Promoting Angiogenesis in Mouse Lung by Transcriptional Profiling American Journal of Respiratory Cell and Molecular Biology. Aug, 2003 | Pubmed ID: 12600816 Interpreting Penh in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2003 | Pubmed ID: 12531918 שיטות החדרה וקיבוע שימושיות בחקר סרטן ריאות עכבר Nathachit Limjunyawong1, Jason Mock2, Wayne Mitzner1 1Bloomberg School of Public Health, Environmental Health Sciences, Johns Hopkins University, 2Department of Medicine, Pulmonary Diseases and Critical Care Medicine, University of North Carolina School of Medicine JoVE 52964 의학 מדידה של עקומת לחץ-נפח ריאות עכבר Nathachit Limjunyawong1, Jonathan Fallica1, Maureen R. Horton1, Wayne Mitzner1 1Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University 의학 פונקצית phenotyping עכבר ריאתי Nathachit Limjunyawong1, Jonathan Fallica1, Amritha Ramakrishnan2, Kausik Datta3, Matthew Gabrielson1, Maureen Horton1, Wayne Mitzner1 1Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, 2Department of International Health, Johns Hopkins University Bloomberg School of Public Health, 3Department of Medicine, Johns Hopkins University School of Medicine 생물학 שיטה פשוטה של אינטובציה ריאות המאוסות Sandhya Das1, Kelvin MacDonald2, Herng-Yu Sucie Chang1, Wayne Mitzner1 1Department of Environmental Health Sciences, Program in Respiratory Biology and Lung Disease, Johns Hopkins Bloomberg School of Public Health, 2Department of Pediatrics, Oregon Health Sciences University JoVE 50318 의학
שיטות החדרה וקיבוע שימושיות בחקר סרטן ריאות עכבר Nathachit Limjunyawong1, Jason Mock2, Wayne Mitzner1 1Bloomberg School of Public Health, Environmental Health Sciences, Johns Hopkins University, 2Department of Medicine, Pulmonary Diseases and Critical Care Medicine, University of North Carolina School of Medicine JoVE 52964 의학
מדידה של עקומת לחץ-נפח ריאות עכבר Nathachit Limjunyawong1, Jonathan Fallica1, Maureen R. Horton1, Wayne Mitzner1 1Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University 의학
פונקצית phenotyping עכבר ריאתי Nathachit Limjunyawong1, Jonathan Fallica1, Amritha Ramakrishnan2, Kausik Datta3, Matthew Gabrielson1, Maureen Horton1, Wayne Mitzner1 1Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, 2Department of International Health, Johns Hopkins University Bloomberg School of Public Health, 3Department of Medicine, Johns Hopkins University School of Medicine 생물학
שיטה פשוטה של אינטובציה ריאות המאוסות Sandhya Das1, Kelvin MacDonald2, Herng-Yu Sucie Chang1, Wayne Mitzner1 1Department of Environmental Health Sciences, Program in Respiratory Biology and Lung Disease, Johns Hopkins Bloomberg School of Public Health, 2Department of Pediatrics, Oregon Health Sciences University JoVE 50318 의학