William J. Janssen Division of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine National Jewish Health Biography Publications Institution JoVE Articles William J. Janssen has not added a biography. If you are William J. Janssen and would like to personalize this page please email our Author Liaison for assistance. Publications Disulfide Disruption Reverses Mucus Dysfunction in Allergic Airway Disease Nature Communications. 01, 2021 | Pubmed ID: 33431872 Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes Cell Reports. Nov, 2020 | Pubmed ID: 33147458 Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults American Journal of Respiratory and Critical Care Medicine. Oct, 2020 | Pubmed ID: 33079572 Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation JCI Insight. 06, 2020 | Pubmed ID: 32343675 Localization of Macrophages in the Human Lung Via Design-based Stereology American Journal of Respiratory and Critical Care Medicine. 05, 2020 | Pubmed ID: 32197050 NF-κB Mediates Lipopolysaccharide-induced Alternative Pre-mRNA Splicing of in Mouse Macrophages The Journal of Biological Chemistry. 05, 2020 | Pubmed ID: 32179652 Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages G3 (Bethesda, Md.). 02, 2020 | Pubmed ID: 31810980 Interstitial Macrophage-derived Thrombospondin-1 Contributes to Hypoxia-induced Pulmonary Hypertension Cardiovascular Research. Oct, 2020 | Pubmed ID: 31710666 Inflammation Via Myeloid Differentiation Primary Response Gene 88 Signaling Mediates the Fibrotic Response to Implantable Synthetic Poly(ethylene Glycol) Hydrogels Acta Biomaterialia. 12, 2019 | Pubmed ID: 31568879 Redistribution of EC-SOD Resolves Bleomycin-induced Inflammation Increased Apoptosis of Recruited Alveolar Macrophages FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 12, 2019 | Pubmed ID: 31560857 Single Cell RNA Sequencing Identifies Unique Inflammatory Airspace Macrophage Subsets JCI Insight. 03, 2019 | Pubmed ID: 30721157 Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome The Journal of Allergy and Clinical Immunology. 01, 2019 | Pubmed ID: 30296525 Mucociliary Defense: Emerging Cellular, Molecular, and Animal Models Annals of the American Thoracic Society. 11, 2018 | Pubmed ID: 30431350 Mouse Models of Viral Infection Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29987803 Modulation of Myeloid Cell Function Using Conditional and Inducible Transgenic Approaches Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29987790 Recombinant IFN-β for Postseptic Acute Lung Injury-What's the Mechanism? American Journal of Respiratory Cell and Molecular Biology. 07, 2018 | Pubmed ID: 29957050 Rapid Clearance of Heavy Chain-modified Hyaluronan During Resolving Acute Lung Injury Respiratory Research. 05, 2018 | Pubmed ID: 29855321 Correction To: Dual RNA-seq Reveals Viral Infections in Asthmatic Children Without Respiratory Illness Which Are Associated with Changes in the Airway Transcriptome Genome Biology. 04, 2018 | Pubmed ID: 29636099 Phagocytosis of Microparticles by Alveolar Macrophages During Acute Lung Injury Requires MerTK American Journal of Physiology. Lung Cellular and Molecular Physiology. 01, 2018 | Pubmed ID: 28935638 Deletion of C-FLIP from CD11b Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis American Journal of Respiratory Cell and Molecular Biology. 01, 2018 | Pubmed ID: 28850249 Promoter Specificity and Efficacy in Conditional and Inducible Transgenic Targeting of Lung Macrophages Frontiers in Immunology. 2017 | Pubmed ID: 29225599 Neutrophil Transfer of to Lung Epithelial Cells Dampens Acute Lung Injury in Mice Science Translational Medicine. Sep, 2017 | Pubmed ID: 28931657 TGF-β Activation by Bone Marrow-derived Thrombospondin-1 Causes Schistosoma- and Hypoxia-induced Pulmonary Hypertension Nature Communications. 05, 2017 | Pubmed ID: 28555642 A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension Journal of Immunology (Baltimore, Md. : 1950). 06, 2017 | Pubmed ID: 28500078 High Resolution Computed Tomography Pattern of Usual Interstitial Pneumonia in Rheumatoid Arthritis-associated Interstitial Lung Disease: Relationship to Survival Respiratory Medicine. 05, 2017 | Pubmed ID: 28427540 Cell Origin Dictates Programming of Resident Versus Recruited Macrophages During Acute Lung Injury American Journal of Respiratory Cell and Molecular Biology. 09, 2017 | Pubmed ID: 28421818 Three Unique Interstitial Macrophages in the Murine Lung at Steady State American Journal of Respiratory Cell and Molecular Biology. 07, 2017 | Pubmed ID: 28257233 Power of Place: Intravascular Superoxide Dismutase for Prevention of Acute Respiratory Distress Syndrome American Journal of Respiratory Cell and Molecular Biology. 02, 2017 | Pubmed ID: 28145771 Dual RNA-seq Reveals Viral Infections in Asthmatic Children Without Respiratory Illness Which Are Associated with Changes in the Airway Transcriptome Genome Biology. 01, 2017 | Pubmed ID: 28103897 CD73 Regulates Anti-inflammatory Signaling Between Apoptotic Cells and Endotoxin-conditioned Tissue Macrophages Cell Death and Differentiation. 03, 2017 | Pubmed ID: 28060378 Scratching Below the Surface The New England Journal of Medicine. 12, 2016 | Pubmed ID: 27959764 Myeloid Cell Turnover and Clearance Microbiology Spectrum. 11, 2016 | Pubmed ID: 27837740 Control of Lung Defence by Mucins and Macrophages: Ancient Defence Mechanisms with Modern Functions The European Respiratory Journal. 10, 2016 | Pubmed ID: 27587549 Selective and Inducible Targeting of CD11b+ Mononuclear Phagocytes in the Murine Lung with HCD68-rtTA Transgenic Systems American Journal of Physiology. Lung Cellular and Molecular Physiology. 07, 2016 | Pubmed ID: 27190063 Mucins and Their Sugars. Critical Mediators of Hyperreactivity and Inflammation Annals of the American Thoracic Society. Mar, 2016 | Pubmed ID: 27027967 MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part Via SIRT1 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2016 | Pubmed ID: 26718338 Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes American Journal of Respiratory and Critical Care Medicine. Mar, 2016 | Pubmed ID: 26551758 The Causal Role of IL-4 and IL-13 in Schistosoma Mansoni Pulmonary Hypertension American Journal of Respiratory and Critical Care Medicine. Oct, 2015 | Pubmed ID: 26192556 Tracheal Dysplasia Precedes Bronchial Dysplasia in Mouse Model of N-nitroso Trischloroethylurea Induced Squamous Cell Lung Cancer PloS One. 2015 | Pubmed ID: 25860262 Conceptual Approaches to Lung Injury and Repair Annals of the American Thoracic Society. Mar, 2015 | Pubmed ID: 25830855 The Polymeric Mucin Muc5ac is Required for Allergic Airway Hyperreactivity Nature Communications. Feb, 2015 | Pubmed ID: 25687754 Endogenous Airway Mucins Carry Glycans That Bind Siglec-F and Induce Eosinophil Apoptosis The Journal of Allergy and Clinical Immunology. May, 2015 | Pubmed ID: 25497369 General Parity Between Trio and Pairwise Breeding of Laboratory Mice in Static Caging Journal of Immunology (Baltimore, Md. : 1950). Nov, 2014 | Pubmed ID: 25381356 Kinetics of the Angiogenic Response in Lung Endothelium Following Acute Inflammatory Injury with Bleomycin Experimental Lung Research. Oct, 2014 | Pubmed ID: 25153689 Dendritic Cell Subsets Require Cis-activation for Cytotoxic CD8 T-cell Induction Nature Communications. Aug, 2014 | Pubmed ID: 25135627 Fas Ligand-expressing Lymphocytes Enhance Alveolar Macrophage Apoptosis in the Resolution of Acute Pulmonary Inflammation American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2014 | Pubmed ID: 24838751 Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts Through TGF-β Responsiveness The American Journal of Pathology. May, 2014 | Pubmed ID: 24650563 Muc5b is Required for Airway Defence Nature. Jan, 2014 | Pubmed ID: 24317696 Circulating Hematopoietic Progenitor Cells Are Decreased in COPD COPD. Jun, 2014 | Pubmed ID: 24182349 The Fibroproliferative Response in Acute Respiratory Distress Syndrome: Mechanisms and Clinical Significance The European Respiratory Journal. Jan, 2014 | Pubmed ID: 23520315 Alveolar Macrophage Dysfunction and Chronic Alcohol Use. Time to Think About Zinc American Journal of Respiratory and Critical Care Medicine. Sep, 2013 | Pubmed ID: 24032380 Chest CT Features Are Associated with Poorer Quality of Life in Acute Lung Injury Survivors Critical Care Medicine. Feb, 2013 | Pubmed ID: 23263616 Defective Efferocytosis by Alveolar Macrophages in IPF Patients Respiratory Medicine. Dec, 2012 | Pubmed ID: 22999220 Apoptotic Cell Clearance and Fibrotic Lung Disease The European Respiratory Journal. Aug, 2012 | Pubmed ID: 22855466 The Pulmonary Endothelial Glycocalyx Regulates Neutrophil Adhesion and Lung Injury During Experimental Sepsis Nature Medicine. Jul, 2012 | Pubmed ID: 22820644 Increased Lymphatic Vessel Length is Associated with the Fibroblast Reticulum and Disease Severity in Usual Interstitial Pneumonia and Nonspecific Interstitial Pneumonia Chest. Dec, 2012 | Pubmed ID: 22797508 Nrf2 Protects Human Alveolar Epithelial Cells Against Injury Induced by Influenza A Virus Respiratory Research. Jun, 2012 | Pubmed ID: 22672594 Vascular Endothelial Growth Factor Enhances Macrophage Clearance of Apoptotic Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2012 | Pubmed ID: 22307908 Macrophages Mediate Lung Inflammation in a Mouse Model of Ischemic Acute Kidney Injury American Journal of Physiology. Renal Physiology. Feb, 2012 | Pubmed ID: 22114207 Cellular Regulation of the Inflammatory Response Toxicologic Pathology. 2012 | Pubmed ID: 22089838 Fas Determines Differential Fates of Resident and Recruited Macrophages During Resolution of Acute Lung Injury American Journal of Respiratory and Critical Care Medicine. Sep, 2011 | Pubmed ID: 21471090 Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease is Reversed by IFN-γ in a Nitric Oxide-dependent Manner Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20805415 Development and Characterization of a Lung-protective Method of Bone Marrow Transplantation in the Mouse Journal of Immunological Methods. May, 2010 | Pubmed ID: 20347833 TNFalpha Inhibits Apoptotic Cell Clearance in the Lung, Exacerbating Acute Inflammation American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2009 | Pubmed ID: 19648283 Cigarette Smoke Impairs Clearance of Apoptotic Cells Through Oxidant-dependent Activation of RhoA American Journal of Respiratory and Critical Care Medicine. Jun, 2009 | Pubmed ID: 19264974 CD38 Plays a Dual Role in Allergen-induced Airway Hyperresponsiveness American Journal of Respiratory Cell and Molecular Biology. Apr, 2009 | Pubmed ID: 18931329 Dyspnea, Chest Pain, and Altered Mental Status in a 33-year-old Carpenter Chest. Nov, 2008 | Pubmed ID: 18988783 Air-Inflation of Murine Lungs with Vascular Perfusion-Fixation Stacey M. Thomas1, Joseph Bednarek2, William J. Janssen1, Patrick S. Hume1 1Division of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine, National Jewish Health, 2Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Children's Hospital Colorado JoVE 62215 신경과학
Air-Inflation of Murine Lungs with Vascular Perfusion-Fixation Stacey M. Thomas1, Joseph Bednarek2, William J. Janssen1, Patrick S. Hume1 1Division of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine, National Jewish Health, 2Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Children's Hospital Colorado JoVE 62215 신경과학