Xi-Lei Zeng

Publications

• Infant and Adult Human Intestinal Enteroids Are Morphologically and Functionally Distinct
  BioRxiv : the Preprint Server for Biology. Feb, 2024  |   Pubmed ID: 37292968
• Rotavirus-mediated DGAT1 Degradation: A Pathophysiological Mechanism of Viral-induced Malabsorptive Diarrhea
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2023  |   Pubmed ID: 38079544
• Human Intestinal Organoids from Cronkhite-Canada Syndrome Patients Reveal Link Between Serotonin and Proliferation
  The Journal of Clinical Investigation. Nov, 2023  |   Pubmed ID: 37909332
• Human Sapovirus Replication in Human Intestinal Enteroids
  Journal of Virology. Apr, 2023  |   Pubmed ID: 37039654
• Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater
  Emerging Infectious Diseases. Jul, 2022  |   Pubmed ID: 35731177
• Generation of CRISPR-Cas9-mediated Genetic Knockout Human Intestinal Tissue-derived Enteroid Lines by Lentivirus Transduction and Single-cell Cloning
  Nature Protocols. Apr, 2022  |   Pubmed ID: 35197604
• Drivers of Transcriptional Variance in Human Intestinal Epithelial Organoids
  Physiological Genomics. Nov, 2021  |   Pubmed ID: 34612061
• Use of Human Tissue Stem Cell-derived Organoid Cultures to Model Enterohepatic Circulation
  American Journal of Physiology. Gastrointestinal and Liver Physiology. 09, 2021  |   Pubmed ID: 34288725
• Culture and Differentiation of Rabbit Intestinal Organoids and Organoid-derived Cell Monolayers
  Scientific Reports. 03, 2021  |   Pubmed ID: 33686141
• New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids
  MSphere. 01, 2021  |   Pubmed ID: 33504663
• Protein-Functionalized Poly(ethylene Glycol) Hydrogels As Scaffolds for Monolayer Organoid Culture
  Tissue Engineering. Part C, Methods. 01, 2021  |   Pubmed ID: 33334213
• Enteropathogenic Escherichia Coli Infection in Cancer and Immunosuppressed Patients
  Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 05, 2021  |   Pubmed ID: 32930708
• Human Norovirus Exhibits Strain-specific Sensitivity to Host Interferon Pathways in Human Intestinal Enteroids
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2020  |   Pubmed ID: 32907944
• Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection
  MBio. 03, 2020  |   Pubmed ID: 32184242
• Bile Acids and Ceramide Overcome the Entry Restriction for GII.3 Human Norovirus Replication in Human Intestinal Enteroids
  Proceedings of the National Academy of Sciences of the United States of America. 01, 2020  |   Pubmed ID: 31896578
• Two- and Three-Dimensional Bioengineered Human Intestinal Tissue Models for Cryptosporidium
  Methods in Molecular Biology (Clifton, N.J.). 2020  |   Pubmed ID: 31452173
• Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges
  Viruses. Jul, 2019  |   Pubmed ID: 31336765
• Changes of Tight Junction and Interleukin-8 Expression Using a Human Gastroid Monolayer Model of Helicobacter Pylori Infection
  Helicobacter. Jun, 2019  |   Pubmed ID: 30950121
• Human Norovirus Replication in Human Intestinal Enteroids As Model to Evaluate Virus Inactivation
  Emerging Infectious Diseases. 08, 2018  |   Pubmed ID: 30014841
• Novel Segment- and Host-Specific Patterns of Enteroaggregative Adherence to Human Intestinal Enteroids
  MBio. 02, 2018  |   Pubmed ID: 29463660
• Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation
  Cell Reports. 01, 2018  |   Pubmed ID: 29386123
• Role for FimH in Extraintestinal Pathogenic Escherichia Coli Invasion and Translocation Through the Intestinal Epithelium
  Infection and Immunity. 11, 2017  |   Pubmed ID: 28808163
• Gastrointestinal Microphysiological Systems
  Experimental Biology and Medicine (Maywood, N.J.). 10, 2017  |   Pubmed ID: 28534432
• Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections
  Methods in Molecular Biology (Clifton, N.J.). Mar, 2017  |   Pubmed ID: 28361480
• A Paradox of Transcriptional and Functional Innate Interferon Responses of Human Intestinal Enteroids to Enteric Virus Infection
  Proceedings of the National Academy of Sciences of the United States of America. 01, 2017  |   Pubmed ID: 28069942
• Replication of Human Noroviruses in Stem Cell-derived Human Enteroids
  Science (New York, N.Y.). 09, 2016  |   Pubmed ID: 27562956
• Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology
  Journal of Virology. 01, 2016  |   Pubmed ID: 26446608
• Human Enteroids As an Ex-vivo Model of Host-pathogen Interactions in the Gastrointestinal Tract
  Experimental Biology and Medicine (Maywood, N.J.). Sep, 2014  |   Pubmed ID: 24719375
• Human Enteroids: Preclinical Models of Non-inflammatory Diarrhea
  Stem Cell Research & Therapy. 2013  |   Pubmed ID: 24564938
• A Time-resolved Immunoassay to Measure Serum Antibodies to the Rotavirus VP6 Capsid Protein
  Journal of Virological Methods. Apr, 2013  |   Pubmed ID: 23183143
• Stem Cell-derived Human Intestinal Organoids As an Infection Model for Rotaviruses
  MBio. 2012  |   Pubmed ID: 22761392