Zhao-lei Zeng State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Sun Yat-sen University Cancer Center Biography Publications Institution JoVE Articles Zhao-lei Zeng has not added a biography. If you are Zhao-lei Zeng and would like to personalize this page please email our Author Liaison for assistance. Publications The Prognostic Value of Aspartate Aminotransferase to Lymphocyte Ratio and Systemic Immune-inflammation Index for Overall Survival of Hepatocellular Carcinoma Patients Treated with Palliative Treatments Journal of Cancer. 2019 | Pubmed ID: 31258733 METTL3 Facilitates Tumor Progression Via an MA-IGF2BP2-dependent Mechanism in Colorectal Carcinoma Molecular Cancer. Jun, 2019 | Pubmed ID: 31230592 Suppression of Fumarate Hydratase Activity Increases the Efficacy of Cisplatin-mediated Chemotherapy in Gastric Cancer Cell Death & Disease. May, 2019 | Pubmed ID: 31138787 Eukaryotic Initiation Factor 4A2 Promotes Experimental Metastasis and Oxaliplatin Resistance in Colorectal Cancer Journal of Experimental & Clinical Cancer Research : CR. May, 2019 | Pubmed ID: 31088567 Genome-wide Profiling of Epstein-Barr Virus Integration by Targeted Sequencing in Epstein-Barr Virus Associated Malignancies Theranostics. 2019 | Pubmed ID: 30867819 Correlation Between Immune Signature and High-density Lipoprotein Cholesterol Level in Stage II/III Colorectal Cancer Cancer Medicine. Mar, 2019 | Pubmed ID: 30729718 A Two-microRNA-based Signature Predicts First-line Chemotherapy Outcomes in Advanced Colorectal Cancer Patients Cell Death Discovery. 2018 | Pubmed ID: 30588338 Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications Journal of the National Cancer Institute. Dec, 2018 | Pubmed ID: 30534944 The Clinical and Biomarker Association of Programmed Death Ligand 1 and Its Spatial Heterogeneous Expression in Colorectal Cancer Journal of Cancer. 2018 | Pubmed ID: 30519336 Phase II Clinical Trial of S-1 Plus Nanoparticle Albumin-bound Paclitaxel in Untreated Patients with Metastatic Gastric Cancer Cancer Science. Nov, 2018 | Pubmed ID: 30281875 Liquid Biopsies to Track Trastuzumab Resistance in Metastatic HER2-positive Gastric Cancer Gut. Sep, 2018 | Pubmed ID: 30269082 CPT1A-mediated Fatty Acid Oxidation Promotes Colorectal Cancer Cell Metastasis by Inhibiting Anoikis Oncogene. 11, 2018 | Pubmed ID: 29995871 ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis Cancer Research. 04, 2018 | Pubmed ID: 29654155 Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation Theranostics. 2018 | Pubmed ID: 29507622 Elevated Baseline Serum Lactate Dehydrogenase Indicates a Poor Prognosis in Primary Duodenum Adenocarcinoma Patients Journal of Cancer. 2018 | Pubmed ID: 29483956 Pharmacological Inhibition of DUSP6 Suppresses Gastric Cancer Growth and Metastasis and Overcomes Cisplatin Resistance Cancer Letters. 01, 2018 | Pubmed ID: 29050982 Long Non-coding RNA UICLM Promotes Colorectal Cancer Liver Metastasis by Acting As a CeRNA for MicroRNA-215 to Regulate ZEB2 Expression Theranostics. 2017 | Pubmed ID: 29187907 Long Noncoding RNA XIST Expedites Metastasis and Modulates Epithelial-mesenchymal Transition in Colorectal Cancer Cell Death & Disease. 08, 2017 | Pubmed ID: 28837144 Hepatitis B Virus Infection is Associated with Younger Median Age at Diagnosis and Death in Cancers International Journal of Cancer. 07, 2017 | Pubmed ID: 28369849 Phase II Trial of S-1 Plus Leucovorin in Patients with Advanced Gastric Cancer and Clinical Prediction by S-1 Pharmacogenetic Pathway Cancer Chemotherapy and Pharmacology. Jan, 2017 | Pubmed ID: 27913881 Melatonin Enhances Sensitivity to Fluorouracil in Oesophageal Squamous Cell Carcinoma Through Inhibition of Erk and Akt Pathway Cell Death & Disease. 10, 2016 | Pubmed ID: 27787516 Long Non-coding RNA XIST Regulates Gastric Cancer Progression by Acting As a Molecular Sponge of MiR-101 to Modulate EZH2 Expression Journal of Experimental & Clinical Cancer Research : CR. 09, 2016 | Pubmed ID: 27620004 Inhibition of the NF-κB Pathway by Nafamostat Mesilate Suppresses Colorectal Cancer Growth and Metastasis Cancer Letters. 09, 2016 | Pubmed ID: 27322737 Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications Theranostics. 2016 | Pubmed ID: 27279909 Comparison of KRAS Mutation Status Between Primary Tumor and Metastasis in Chinese Colorectal Cancer Patients Medical Oncology (Northwood, London, England). Jul, 2016 | Pubmed ID: 27270901 Effect of Raf Kinase Inhibitor Protein Expression on Malignant Biological Behavior and Progression of Colorectal Cancer Oncology Reports. Oct, 2015 | Pubmed ID: 26238523 Micro-RNA-155 is Induced by K-Ras Oncogenic Signal and Promotes ROS Stress in Pancreatic Cancer Oncotarget. Aug, 2015 | Pubmed ID: 26020803 MicroRNA-217 Inhibits Tumor Progression and Metastasis by Downregulating EZH2 and Predicts Favorable Prognosis in Gastric Cancer Oncotarget. May, 2015 | Pubmed ID: 25869101 Identification of NDUFAF1 in Mediating K-Ras Induced Mitochondrial Dysfunction by a Proteomic Screening Approach Oncotarget. Feb, 2015 | Pubmed ID: 25714130 Prognostic Significance and Therapeutic Implications of Peroxisome Proliferator-activated Receptor γ Overexpression in Human Pancreatic Carcinoma International Journal of Oncology. Jan, 2015 | Pubmed ID: 25333644 Clinicopathologic and Prognostic Relevance of ARID1A Protein Loss in Colorectal Cancer World Journal of Gastroenterology. Dec, 2014 | Pubmed ID: 25561809 Reduced Expression of P21-activated Protein Kinase 1 Correlates with Poor Histological Differentiation in Pancreatic Cancer BMC Cancer. Sep, 2014 | Pubmed ID: 25182632 Identification of MicroRNA-214 As a Negative Regulator of Colorectal Cancer Liver Metastasis by Way of Regulation of Fibroblast Growth Factor Receptor 1 Expression Hepatology (Baltimore, Md.). Aug, 2014 | Pubmed ID: 24616020 Increased Expression of EIF5A2, Via Hypoxia or Gene Amplification, Contributes to Metastasis and Angiogenesis of Esophageal Squamous Cell Carcinoma Gastroenterology. Jun, 2014 | Pubmed ID: 24561231 Prognostic Relevance of Period1 (Per1) and Period2 (Per2) Expression in Human Gastric Cancer International Journal of Clinical and Experimental Pathology. 2014 | Pubmed ID: 24551282 S-1-based Chemotherapy Versus Capecitabine-based Chemotherapy As First-line Treatment for Advanced Gastric Carcinoma: a Meta-analysis PloS One. 2013 | Pubmed ID: 24349363 Abnormal Expression of Paxillin Correlates with Tumor Progression and Poor Survival in Patients with Gastric Cancer Journal of Translational Medicine. Nov, 2013 | Pubmed ID: 24180516 L1cam Promotes Tumor Progression and Metastasis and is an Independent Unfavorable Prognostic Factor in Gastric Cancer Journal of Hematology & Oncology. Jun, 2013 | Pubmed ID: 23806079 CDC20 Overexpression Predicts a Poor Prognosis for Patients with Colorectal Cancer Journal of Translational Medicine. Jun, 2013 | Pubmed ID: 23758705 Targeting CDH17 Suppresses Tumor Progression in Gastric Cancer by Downregulating Wnt/β-catenin Signaling PloS One. 2013 | Pubmed ID: 23554857 Decreased Expression of the Mitochondrial Metabolic Enzyme Aconitase (ACO2) is Associated with Poor Prognosis in Gastric Cancer Medical Oncology (Northwood, London, England). Jun, 2013 | Pubmed ID: 23550275 Overexpression of Paxillin Induced by MiR-137 Suppression Promotes Tumor Progression and Metastasis in Colorectal Cancer Carcinogenesis. Apr, 2013 | Pubmed ID: 23275153 β-phenylethyl Isothiocyanate Reverses Platinum Resistance by a GSH-dependent Mechanism in Cancer Cells with Epithelial-mesenchymal Transition Phenotype Biochemical Pharmacology. Feb, 2013 | Pubmed ID: 23219523 Prognostic Relevance of Melanoma Antigen D1 Expression in Colorectal Carcinoma Journal of Translational Medicine. Aug, 2012 | Pubmed ID: 22935435 Copper-transporting P-type Adenosine Triphosphatase (ATP7A) is Associated with Platinum-resistance in Non-small Cell Lung Cancer (NSCLC) Journal of Translational Medicine. Feb, 2012 | Pubmed ID: 22304828 HBV Infection Decreases Risk of Liver Metastasis in Patients with Colorectal Cancer: A Cohort Study World Journal of Gastroenterology. Feb, 2011 | Pubmed ID: 21390153 DNA Polymerase η Protein Expression Predicts Treatment Response and Survival of Metastatic Gastric Adenocarcinoma Patients Treated with Oxaliplatin-based Chemotherapy Journal of Translational Medicine. Nov, 2010 | Pubmed ID: 21110884 Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines Jia-huan Lu*1, Yun Wang*1, Qi Meng*1, Zhao-lei Zeng1 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center JoVE 59871 암 연구학
Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines Jia-huan Lu*1, Yun Wang*1, Qi Meng*1, Zhao-lei Zeng1 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center JoVE 59871 암 연구학