1Department of Neurosurgery,Duke University Medical Center, 2Department of Anesthesiology and Pain Management,University Texas Southwestern Medical School, 3Department of Neurobiology,Duke University Medical Center, 4Department of Biomedical Engineering,Duke University, 5Research and Surgery Services,Durham VA Medical Center
我们描述了一种评估颅外刺激剂量反应曲线的方案，包括脑电场测量和相关的生物标志物-脑血流。由于该方案涉及将侵入性电极植入大脑，因此需要全身麻醉，首选自主呼吸而不是控制呼吸。
