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Chapters
- 00:05Title
- 02:02Introduction
- 02:37Preparation of the Animal Model
- 02:59Nanoparticle Fabrication
- 06:07In Vivo Ultrasound to Perform Targeted Drug Delivery
- 07:12Nanoparticle Biodistribution
- 10:44Tumor Growth Rate
- 11:22Tumor Processing and Analysis
- 12:21Representative Results
- 13:24Conclusion
Insonation van microbellen is een veelbelovende strategie voor tumor ablatie op kortere gemiddelde akoestische bevoegdheden, alsmede voor de gerichte toediening van geneesmiddelen. Het doel van deze studie is het ontwikkelen van low duty cycle echografie pulserende strategieën en nanocarriers aan niet-thermische microvasculair ablatie en laadvermogen levering aan subcutane C6 glioma te maximaliseren.
Tags
Contrast UltrasoundTargeted TreatmentGliomasMiceDrug-bearing NanoparticlesMicrovascular AblationMinimally-invasiveContrast Agent MicrobubbleUltrasound Pulsing ParametersMalignant Brain TumorsDrug DeliveryComposite Delivery AgentsPoly(lactide-co-glycolide) NanoparticlesAlbumin Shelled MicrobubblesSubcutaneous C6 GliomasNanoparticle DeliveryMicrobubble-nanoparticle Composite Agents (MNCAs)Cancer ApplicationsTumor MicrocirculationTumor HypoxiaApoptosisNon-thermal Cavitation-induced Microvascular Ablation
