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Bioengineering

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JoVE Journal Bioengineering
Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
 

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Article DOI: 10.3791/2545-v • 09:46 min • February 4th, 2011
February 4th, 2011 •
1,2, 1,2, 1,2, 2,3, 1,2,4
1Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, 2Micro and Nanotechnology Lab, University of Illinois at Urbana-Champaign, 3Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 4Bioengineering, University of Illinois at Urbana-Champaign

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요약
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Dielectrophoresis (DEP) is an effective method to manipulate cells. Printed circuit boards (PCB) can provide inexpensive, reusable and effective electrodes for contact-free cell manipulation within microfluidic devices. By combining PDMS-based microfluidic channels with coverslips on PCBs, we demonstrate bead and cell manipulation and separation within multichannel microfluidic devices.

Tags

Microfluidic Devices Cell Studies Fluidic Environment Manipulating Cells Sorting Cells Counting Cells Dielectrophoresis Laminar Flow Printed Circuit Boards (PCBs) Non-contact Manipulation Bead Manipulation Cell Manipulation Bioactuation Cell Separation Multichannel Microfluidic Devices DEP Electrodes
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