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Evaluation of Cancer Stem Cell Migration Mit Abschottung Mikrofluidiksysteme und Live Cell Imaging
 
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Evaluation of Cancer Stem Cell Migration Mit Abschottung Mikrofluidiksysteme und Live Cell Imaging

Article DOI: 10.3791/3297-v • 09:37 min • December 23rd, 2011
December 23rd, 2011 •
*1,2, *3, 3, 1,2,3, 3,4
1Department of Biomedical Engineering, University of Wisconsin-Madison, 2Materials Science Program, University of Wisconsin-Madison, 3Department of Neurological Surgery, University of Wisconsin-Madison, 4Carbone Comprehensive Cancer Center and Center for Stem Cell and Regenerative Medicine, University of Wisconsin-Madison
* These authors contributed equally

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Eine Abschottung mikrofluidischen Vorrichtung zur Untersuchung von Krebsstammzellen Migration beschrieben. Diese neuartige Plattform schafft eine tragfähige zellulären Mikroumgebung und ermöglicht mikroskopische Visualisierung der lebenden Zelle Fortbewegung. Höchst beweglich Krebszellen isoliert sind, um molekularen Mechanismen von aggressiven Infiltration, was möglicherweise zur wirksameren zukünftige Therapien.

Tags

Medizin BTSC Tumor Krebsstammzellen Zellmigration Mikrofluidik Glioblastoma multiforme GBM Chemotaxis amoeboid mesenchymalen Haptotaxis PDMS
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