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Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
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Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

DOI:
10.3791/51041-v

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10:33 min

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February 03, 2014

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, , , , , , , , ,
1Cardiac Muscle Research Labratory, Cardiovascular Division, Brigham and Women’s Hospital,Harvard Medical School, 2Cardiovascular Department,Chang Gung Memorial Hospital

Chapters

  • 00:05Title
  • 01:39Surgical Procedure and Anesthesia
  • 02:42Echocardiographic Image Acquisition and Measurements
  • 07:06Data Calculation and Analysis
  • 08:16Results: Right Ventricular Structure and Function in Mice
  • 09:46Conclusion

Summary

자동 번역

자동 번역

Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.

Tags

Right Ventricular StructureRight Ventricular FunctionPulmonary Artery ConstrictionTransthoracic EchocardiographyMouse ModelCardiac PathologyPressure GradientVentricular DysfunctionPulmonary Artery HypertensionNoninvasive AssessmentEchocardiographic Measurements

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