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Chapters
- 00:05Title
- 01:55Equipment Set Up for Measurement of Oscillatory Lower Body Negative Pressure
- 05:04Measurement of Oscillatory Lower Body Negative Pressure
- 06:15Projection Pursuit Regression
- 08:05Results: Cerebral Autoregulation after Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
- 10:58Conclusion
Cerebral perfusion is maintained across a range of pressures via cerebral autoregulation. However, characterizing autoregulation requires prominent pressure fluctuations at regulated frequencies. The described protocol will show how oscillatory lower body negative pressure can generate pressure fluctuations to provide data for projection pursuit regression for quantification of the autoregulatory curve.
