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JoVE Journal Neuroscience
In vivo billeddannelse af Optic Nerve Fiber Integritet ved kontrast-forstærket MRI i mus
 
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In vivo billeddannelse af Optic Nerve Fiber Integritet ved kontrast-forstærket MRI i mus

Article DOI: 10.3791/51274-v • 11:38 min • July 22nd, 2014
July 22nd, 2014 •
*1, *2, 3, 3, 1, 2, 1, 2
1Hans Berger Department of Neurology, Jena University Hospital, 2Immunology, Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group, Jena University Hospital
* These authors contributed equally

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Denne video illustrerer en metode, ved hjælp af en klinisk 3 T scanner til kontrast-forstærkede MR scanning af det naive mus visuel projektion og til gentagne og langsgående in vivo studier af synsnerven degeneration er forbundet med akut synsnerven crush skade og kronisk synsnerven degeneration i knock-out mus (p50 KO).

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Neuroscience mangan-forstærket MRI mus Retino-tectal projektion visuelle system neurodegeneration synsnerven skade NF-KB
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