Journal
/
/
Excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
JoVE 신문
의학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 의학
Excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
DOI:

07:00 min

February 04, 2014

, , ,

Chapters

  • 00:05Title
  • 01:08Preparation of Microslices
  • 02:27Equilibration of Microslices
  • 03:46Excitotoxic Stimulation
  • 05:26Results: Viability of Microslices
  • 06:41Conclusion

Summary

자동 번역

We have developed a brain slice model which can be used to examine molecular mechanisms involved in excitotoxicity-mediated brain injury. This technique generates viable mature brain tissue and reduces animal numbers required for experimentation, whilst keeping the neuronal circuitry, cellular interactions, and postsynaptic compartments partly intact.

Related Videos

Read Article