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通过中级过氧化物的抗病毒四氢咔唑衍生物的合成光化学和酸催化CH官能（筹）
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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
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通过中级过氧化物的抗病毒四氢咔唑衍生物的合成光化学和酸催化CH官能（筹）

DOI:
10.3791/51504-v

•

06:34 min

•

June 20, 2014

•

,
1Max-Planck-Institut fuer Kohlenforschung

Chapters

  • 00:05Title
  • 01:34Synthesis of Tetrahydrocarbazole Hydroperoxides
  • 02:45Coupling Reaction – Method A Using 10 mol% Trifluoroacetic Acid in Methanol
  • 04:03Coupling Reaction – Method B Using Acetic Acid
  • 04:52Results: Synthesis of Pharmaceutically Active Tetrahydrocarbazoles
  • 06:06Conclusion

Summary

자동 번역

자동 번역

A two-step procedure for the synthesis of pharmaceutically active indole-derivatives by C-H functionalization with anilines is described, using photo- and Brønsted acid catalysis.

Tags

Keywords: C-H FunctionalizationPhotochemistryOxidationPeroxidesTetrahydrocarbazolesAntiviral CompoundsGreen Chemistry

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