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JoVE Journal
Bioengineering

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Construction and Characterization of a Novel Vocal Fold Bioreactor
 

Construction and Characterization of a Novel Vocal Fold Bioreactor

Article DOI: 10.3791/51594-v 11:11 min August 1st, 2014
August 1st, 2014

챕터

요약

A novel vocal fold bioreactor capable of delivering physiologically relevant, vibratory stimulation to cultured cells is constructed and characterized. This dynamic culture device, when combined with a fibrous poly(ε-caprolactone) scaffold, creates a vocal fold-mimetic environment that modulates the behaviors of mesenchymal stem cells.

Tags

Keywords: Vocal Fold Bioreactor In Vitro Tissue Engineering Vibration Stimulation Mechanotransduction Extracellular Matrix Mesenchymal Stem Cells
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