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Immunology and Infection

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Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection
 

Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection

Article DOI: 10.3791/51668-v 11:49 min June 12th, 2014
June 12th, 2014

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요약

Human infection by Entamoeba histolytica leads to amoebiasis, a major cause of diarrhea in tropical countries. Infection is initiated by pathogen interactions with intestinal epithelial cells, provoking the opening of cell-cell contacts and consequently diarrhea, sometimes followed by liver infection. This article provides a model to assess the early host-pathogen interactions to improve our understanding of amoebiasis pathogenesis.

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Keywords: Entamoeba Histolytica Amoebiasis Epithelial Damage Tight Junctions EhCPADH112 Host-pathogen Interaction Epithelial Barrier Dysfunction Transepithelial Electrical Resistance Epithelial Surface Receptors Epithelial Junctional Markers Parasite Localization
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