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שיבוש Reconsolidation של פחד זיכרון בבני אדם על ידי β-Blocker noradrenergic
JoVE 신문
행동분석학
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JoVE 신문 행동분석학
Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker
DOI:

08:32 min

December 18, 2014

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Chapters

  • 00:05Title
  • 00:59Fear Potentiated Startle and Shock Electrodes
  • 03:03Fear Acquisition – Day 1
  • 04:27Memory Reactivation – Day 2
  • 05:59Test – Day 3
  • 07:20Results: Disrupted Fear Memory after Propranolol Treatment
  • 08:08Conclusion

Summary

자동 번역

Disrupting reconsolidation is a promising approach to dampen the behavioral expression of fear memory in patients with anxiety disorders or posttraumatic stress disorder. In a series of human fear conditioning studies we showed that disrupting reconsolidation by the noradrenergic β-blocker propranolol is very effective in erasing conditioned fear responding.

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