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Chapters
- 00:05Title
- 01:25Left Pulmonary Artery Ligation
- 02:36Right Lower Lobe Pulmonary Artery Embolization
- 03:39Hemodynamic Assessment and Echocardiogarphic Assessment of the Right Ventricle
- 04:37Pressure-Volume Loop Assessment and Endomycocardial Biopsy of the Right Ventricle
- 07:10Results: Representative Chronic Pulmonary Hypertension Model Analysis
- 08:55Conclusion
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
