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Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
 

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

Article DOI: 10.3791/53760-v 07:53 min April 26th, 2016
April 26th, 2016

챕터

요약

The most commonly used method for nanostructured lipid carrier (NLC) synthesis involves oil-in-water emulsion, homogenization and solidification. This was modified here by applying high shear dispersion after solidification to achieve a NLC with desirable size, improved drug encapsulation and drug loading efficiency as a potential carrier for dacarbazine delivery.

Tags

Keywords: Nanostructured Lipid Carrier Dacarbazine Cancer Therapeutic Agent Encapsulation Drug Dispersity Drug Release Control Emulsion Homogenization Dynamic Light Scattering Transmission Electron Microscopy
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