Journal
/
/
מודלים וסימולציות של החדרת תרופות חוש ריח באמצעות בקרה פסיבית ואקטיבית של אירוסולים תרופות בשאיפת nasally
JoVE 신문
의학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 의학
Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
DOI:

15:04 min

May 20, 2016

,

Chapters

  • 00:05Title
  • 01:06Image-Based Nasal Airway Preparation
  • 04:32Passive Control of Particles: Intubation
  • 07:37Active Control of Particles: Magnetophoretic Guidance
  • 09:57Testing of 2D/3D Nose Models
  • 12:57Results: Alternative Nasal Devices Through Intubation and Magnetophoretic Guidance Prove Superior to Conventional Methods
  • 14:01Conclusion

Summary

자동 번역

This manuscript reviews the modeling and simulations of different protocols to deliver medications to the olfactory region in image-based nasal airway models. Multiple software modules are used to develop the anatomically accurate nose model, generate computational mesh, simulate nasal airflows, and predict particle deposition at the olfactory region.

Related Videos

Read Article