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דור של איברים ממוזגים מדיה ויישומים עבור לימוד השפעות איבר ספציפי על התנהגות סרטן שד גרורתי
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Generation of Organ-conditioned Media and Applications for Studying Organ-specific Influences on Breast Cancer Metastatic Behavior
DOI:

09:44 min

June 13, 2016

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Chapters

  • 00:05Title
  • 00:47Lymph Node (LN), Lung, Leg Bones, and Brain Isolation
  • 03:29Lung- or Brain-conditioned Medium Generation
  • 04:53Bone Marrow- or LN-conditioned Medium Generation
  • 06:58Results: Representative Organ-specific Influences on Breast Cancer Metastatic Behavior
  • 08:35Conclusion

Summary

자동 번역

This manuscript describes an ex vivo model system comprised of organ-conditioned media derived from the lymph node, bone, lung, and brain of mice. This model system can be used to identify and study organ-derived soluble factors and their effects on the organ tropism and metastatic behavior of cancer cells.

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