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A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
 

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

Article DOI: 10.3791/54722-v 09:57 min December 23rd, 2016
December 23rd, 2016

챕터

요약

To deliver cancer drugs to tumor sites with high specificity and reduced side effects, new methods based on nanoparticles are required. Here, we describe disulfide cross-linked micelles that can be easily prepared by hydrogen peroxide-mediated oxidation and are able to dissociate efficiently under a reducing tumor environment to release payloads.

Tags

Keywords: Disulfide Cross-linked Micelles Drug Delivery Nano-formulations Polyethylene Glycol Cholic Acid N,N-Diisopropylethylamine DMF Centrifugation Ether Precipitation Polymer Synthesis
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