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JoVE Journal Neuroscience
Subpial Adeno-assoziiertes Virus 9 (AAV9) Vektorlieferung in erwachsenen Mäusen
 
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Subpial Adeno-assoziiertes Virus 9 (AAV9) Vektorlieferung in erwachsenen Mäusen

Article DOI: 10.3791/55770-v • 08:32 min • July 13th, 2017
July 13th, 2017 •
1, 1, 1, 1, 2, 2, 1, 1, 3, 3, 3, 4, 4, 1,4
1Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, 2Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 3Department of Neurosurgery, University of California, San Diego, 4Institute of Neurobiology, Slovak Academy of Sciences

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Das Ziel der vorliegenden Studie war es, die Potenz und Sicherheit der spinalen Adeno-assoziierten Virus 9 (AAV9) -vermittelten Genabgabe zu entwickeln und zu validieren, indem eine neuartige subpiale Genabgabetechnik bei erwachsenen Mäusen verwendet wurde.

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Neurowissenschaften Ausgabe 125 Maus subpiale spinale Genabgabe AAV9 GFP-Expression
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