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Journal / Bioengineering / 三维组织工程化排列的星形胶质细胞网络,…
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Bioengineering

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JoVE Journal Bioengineering
三维组织工程化排列的星形胶质细胞网络, 以概括发展机制和促进神经系统再生
 
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三维组织工程化排列的星形胶质细胞网络, 以概括发展机制和促进神经系统再生

Article DOI: 10.3791/55848-v • 08:56 min • January 10th, 2018
January 10th, 2018 •
*1,2,3, *1,2,4, 1,2,4, 1,2, 1,5, 1,5, 1,2,4, 1,2,5
1Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2Center for Neurotrauma, Neurodegeneration & Restoration, Michael J. Crescenz Veterans Affairs Medical Center, 3School of Biomedical Engineering, Drexel University, 4Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 5Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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我们展示了自组装的发展, 三维束纵向排列星胞和过程内的新型生物材料装箱。这些被设计的 "活脚手架", 显示微米尺度的直径, 但长度延长厘米, 可作为试验床研究神经发育机制或促进 neuroregeneration 通过引导神经元迁移和/或轴突寻.

Tags

生物工程 问题 131 神经组织工程 活支架 神经 neuroregeneration 细胞迁移 轴突寻 星形胶质细胞网络 神经干细胞
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