Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Contractility Measurements of Human Uterine…
JoVE Journal
Medicine

이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.

JoVE Journal Medicine
Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
 

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development

Article DOI: 10.3791/56639-v • 07:56 min • January 26th, 2018
January 26th, 2018 •
*1, 2, 3,4, *2,5
1Harris-Wellbeing Preterm Birth Research Centre, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, 2School of Biomedical Sciences, The University of Queensland, 3Faculty of Chemistry, Institute of Biological Chemistry, University of Vienna, 4Institute for Molecular Bioscience, University of Queensland, 5Center for Physiology and Pharmacology, Medical University of Vienna
* These authors contributed equally

챕터

요약
Automatic Translation

This article describes experimental protocols to study ex vivo contractions of human myometrium and their application in drug discovery. This technique is used to improve the understanding of myometrial physiology and pathophysiology as well as to validate pharmacological data from novel research probes or drug leads.

Tags

Contractility Measurements Human Uterine Smooth Muscle Drug Development Agonists Antagonists Novel Agents Ex Vivo Myometrial Contractions Myometrial Physiology Pharmacological Data Preterm Birth Dysfunctional Labor Technique Functional Responses Peristaltic Feeder Tube Peristaltic Pump Head Physiological Saline PSS Pregnant Human Myometrium Biopsy Sample Dissection Dish Serosa Decidua Edges
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter