Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Medicine

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
 

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Article DOI: 10.3791/56714-v 08:46 min December 28th, 2017
December 28th, 2017

챕터

요약

This study implemented whole genome sequencing for analysis of mutations in genes conferring antifungal drug resistance in Candida glabrata. C. glabrata isolates resistant to echinocandins, azoles and 5-flucytosine, were sequenced to illustrate the methodology. Susceptibility profiles of the isolates correlated with presence or absence of specific mutation patterns in genes.

Tags

Whole Genome Sequencing Candida Glabrata Antifungal Drug Resistance Mutations Diagnostic Laboratory Fungi Genome-wide Mutations Antifungal Agents Medically Important Fungi Outbreaks Fungal Disease Transmission Events Health Care Settings Emerging Fungal Species Clones Genomic DNA Samples
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter